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DateTitreDurée
12 Apr 2023Ep 113 - Mad Scientist Midgley00:48:43

In today's episode, Harini introduces Megan to Thomas Midgley Jr., the inventor of leaded gasoline and freon, two of the most harmful industrial pollutants to captivate the world. To this day, local environments and the ozone are still on long journeys to recovery. 

In this episode:

Ep. 48 - One Rock to Rule Them All

Ep. 109 - Environmental Disaster Watch: The Norfolk Southern Derailment

See omnystudio.com/listener for privacy information.

12 Oct 2022Spooktober Special: Deathbed Visions and Terminal Lucidity01:02:00

For as long as humans have observed death, we still don't know a lot about what happens cognitively in our final days and hours. Anecdotes of dying loved ones seeing visions of deceased relatives or having moments of lucidity despite battling degenerative neurological diseases have been shared for centuries. What are deathbed visions and terminal (paradoxical) lucidity? Why do these phenomena occur as someone is about to pass? Is there a veil that opens between the human consciousness and a world beyond us? And if so, are these visions actually spirit guides, angels, ghosts, or something else? Megan talks about the empirical data that has been gathered so far about terminal lucidity and deathbed visions. But there are many questions that science has yet to answer...and, to us, that's pretty spooky. 

If you liked this episode please rate, review and subscribe!

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In this episode:

Episode Sources

 

See omnystudio.com/listener for privacy information.

22 Feb 2023E 108 - The Last of Us and Fungus Fever00:52:57

In today's episode, Megan addresses the recent uptick in public interest in fungi and fungal infections as a result of HBO's newest series, The Last of Us. When the series aired, frenzied netizens were quick to take to online forums - Reddit, TikTok - to draw parallels between the show/video game and real life. Zombifying fungi do exist in the real world and the rate of fungal infections have increased in the last six years (possibly due to an increase in global temperature). Scary! But how much stock should we really put into the science behind The Last of Us and frightening fungi? Megan has answers. 

See omnystudio.com/listener for privacy information.

19 Apr 2023Ep 114 - The Philadelphia Latex Spill with Arizona Milotich00:54:07

Yup, there was another latex spill and, yup, we're covering it! Happy Earth Day? In this episode, Harini and Megan chat with long-time friend and Philly resident, Arizona Milotich, about the latex spill in Philadelphia (Delware River) this past March. What happens when the sixth most populous city in the United States suddenly faces water insecurity and uncertainty? Tune in to find out. 

BONUS: Harini provides an update on the ongoing cleanup of East Palestine. 

See omnystudio.com/listener for privacy information.

09 Jun 2021Ep 28 - The Speckled Monster...00:54:30

In light of all the work that went into producing the the COVID-19 vaccine. Harini wanted to go back in time and take us back to the lovely, but slightly dirty 18th century to discuss the very FIRST vaccine ever created for eradicating smallpox! We're calling all milkmaids, surgeons, small children, and red cloth merchants for this episode. 

 

If you liked this episode please rate, review and subscribe!

Follow us on Instagram: @deadlydosepod

TikTok: @tilscience

Email us your homegrown poison stories at deadlydosepod@gmail.com

 

Episode Sources:

  • Image 1: Edward Jenner, the man who created the very first vaccine, inoculating a small child vs smallpox (via Getty Images)

  • Image 2: A graphic of how smallpox can ravage the body (via Medical Xpress)

  • https://www.nytimes.com/2020/05/25/well/family/covid-vaccine-smallpox-coronavirus.html

  • https://www.history.com/news/the-rise-and-fall-of-smallpox

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1200696/

  • https://www.frontiersin.org/articles/10.3389/fimmu.2011.00021/full

  • https://www.sciencemuseum.org.uk/objects-and-stories/medicine/smallpox-and-story-vaccination

See omnystudio.com/listener for privacy information.

02 Mar 2023Ep 109 - Environmental Disaster Watch: The Norfolk Southern Train Derailment00:41:29

We've been keeping a close eye on the Norfolk Southern train derailment in East Palestine, Ohio. It has been over three weeks since the 38-car freight train derailed and leaked toxic chemicals - most significantly, vinyl chloride and butyl acrylate - into the soil. In an effort towards containment, the EPA authorized a control burn of these chemicals which has led to widespread concern, locally and nationally, about dioxin pollution in the air. In addition, the derailment has re-ignited scrutiny towards negligence in the railroad industry. Nearly one month later, how has this disaster impacted the natural environment and civilian health since its occurrence? And what long lasting consequences will the residents of East Palestine and surrounding communities feel in the years to follow?

See omnystudio.com/listener for privacy information.

19 Jan 2022Ep 55 - It's Elementary My Dear (Part 2)01:26:04

Welcome back poison pals to the first episode of 2022. This is as current as it gets with this story of power, (misplaced) ambition, money, deceit, and, of course, blood.

Harini tells the final part of the Elizabeth Holmes story, the tech giant who fell from grace along with her once visionary company called Theranos. This isn't the story you heard so many times through the documentaries - we go deep to the root of what went down. Join us poison pals on this rollercoaster of a story.  

In this episode:

The Rice Krispie Guy: https://www.npr.org/2021/09/14/1036835868/elizabeth-holmes-trial-hotelier-bill-evans-goes-incognito

The Inventor (HBO Max)

Bad Blood: Secrets and Lies in a Silicon Valley Startup by John Carreyrou  

American Scandal Podcast on Theranos 

If you liked this episode please rate, review and subscribe!

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TikTok: @tilscience

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See omnystudio.com/listener for privacy information.

21 Apr 2021Ep 22 - Tough Titties Part I01:18:25

We teased this in the very first episode of The Deadly Dose and now it is finally coming to fruition. The infamous story of the Bhagwan Shree Rajneesh and the fanatic religious movement that resulted in a massive compound in Oregon (Rajneeshpuram), hundreds and thousands of followers, and poison. 

In this episode:

  • Wild Wild Country (series) on Netflix 

  • Bat Shit Valley by Documentary Now (a spoof on Wild Wild Country) on Netflix

 

If you liked this episode please rate, review and subscribe!

Follow us on Instagram: @deadlydosepod

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Email us your homegrown poison stories at deadlydosepod@gmail.com

 

Episode Sources:

  • Image 1: Ma Anand Sheela and Bhagwan Shree Rajneesh (via Netflix)

  • Image 2: Hordes of Rajneeshis in their infamous orange robes at the Rajneeshpuram compound in Oregon (via National Endowment for the Humanities)

  • Image 3: Bhagwan Shree Rajneesh (via PBS)

  • Netflix “Wild Wild Country”

 

See omnystudio.com/listener for privacy information.

07 Jun 2023Ep 118 - MegaSyn and the Greater Conversation Around AI in Healthcare01:02:12

"AI, so hot right now. AI." - Mugatu

In today's episode, Harini and Megan discuss the perceived implications of artificial intelligence (AI) in healthcare. MegaSyn, an AI drug discovery platform originally invented to develop drugs to combat orphan (rare) diseases, made waves in 2021 when it's creators discovered that a simple change of code would lead MegaSyn to generate thousands of known AND novel toxic molecules (for example, VX). Of course, this raised flags across the international healthcare community and posed the questions: what happens if AI falls into the wrong hands, and how can we prevent this from happening? 

See omnystudio.com/listener for privacy information.

19 Oct 2022Spooktober Special: Poisons, Potions, and Potter01:02:33

In today's episode, Harini takes us on a magical voyage through the Potterverse to study a handful of poisons and potions that have become iconic as world-building, plot devices in the series and franchise. Did you know that a majority of these enchanting elixirs and the lore behind them actually exist in the muggle world - our muggle world? Better pay close attention: the Potions Master is in and Professor Bhat does not take kindly to insubordinate witches and wizards.

If you liked this episode please rate, review and subscribe!

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Email us your homegrown poison stories at deadlydosepod@gmail.com

In this episode: Harry Potter (book and films)

Sources:

See omnystudio.com/listener for privacy information.

26 May 2021Ep 26 - 1918 Hot Tub Time Machine!01:15:47

Grab some gloves and a mask because Harini is taking us into her hot tub time machine back to the 1918 Flu Pandemic. Harini highlights three different character stories around the globe to paint us a picture of the Forgotten Flu! 

In this episode:

 

If you liked this episode please rate, review and subscribe!

Follow us on Instagram: @deadlydosepod

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Email us your homegrown poison stories at deadlydosepod@gmail.com

 

Episode Sources:

  • Image 1: A sign of the times not unlike our COVID-19 Pandemic (via Connecticut College)

  • Image 2: Women masked up while working (via The Market Watch)

  • The Times Machine (NYT)

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1997248/

  • https://virus.stanford.edu/uda/

  • https://www.smithsonianmag.com/smart-news/what-happened-when-woodrow-wilson-came-down-1918-flu-180975972/

  • https://www.cnn.com/2020/10/03/us/woodrow-wilson-coronavirus-trnd/index.html

See omnystudio.com/listener for privacy information.

06 Jul 2022Ep 78 - Devil's Snare00:44:51

Spoilers for the Sinner Season 2 ahead!

In this episode, Megan debunks the portrayal of jimson weed in The Sinner Season 2. Though a small feature in the season, it leaves a lasting impression, violently incapacitating and killing two grown adults within minutes in the first episode. While the reality of this nightshade’s toxicity is a lot less frightening than the show would like you to believe, it remains an incredibly compelling plant. Tune in to find out more about this prolific, gorgeous weed that can simultaneously cure and intoxicate.

If you liked this episode please rate, review and subscribe!

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In this episode

  • The Sinner, Season 2 Episode 1
  • Phantom Thread (Movie)
  • Power of the Dog (Movie) 

 

Episode Sources:

·  https://en.wikipedia.org/wiki/Flying_ointment

See omnystudio.com/listener for privacy information.

21 Jul 2021Ep 34 - The Mystery at Loch Maree!01:18:02

You're on vacation in the Scottish Highlands in a picturesque castle-turned-inn with a view of the rolling green hills and many lochs that hold many a secret beneath its surface. But, the biggest secret of 1920s Scotland happened at the hotel Loch Maree. One by one...they all fell sick...one by one...until there were none. The culprit of this story is: botulinum 

In this episode:

  • Sherlock (Netflix) 

 

If you liked this episode please rate, review and subscribe!

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Email us your homegrown poison stories at deadlydosepod@gmail.com

 

Episode Sources:

  • Image 1: Hotel Loch Maree in Scotland (via Atlas Obscura)

  • Image 2: The effect of botulism that can come from canned goods (via The Vintage News)

  • https://www.atlasobscura.com/articles/first-botulism-case

  • https://www.pressandjournal.co.uk/fp/past-times/3906333/loch-maree-botulism/

  • https://www.thevintagenews.com/2018/07/12/botulism-in-1922/

  • https://www.who.int/news-room/fact-sheets/detail/botulism

  • https://en.wikipedia.org/wiki/Botulism

See omnystudio.com/listener for privacy information.

25 May 2022Ep 73 - The Afrin Affair01:21:52

You're getting double the dose of Harini this week. This story is the infamous Afrin Affair of 1991. An esteemed scientist, Dr. Barry Van Winkle, is on the verge of skyrocketing his career when he gets mysteriously targeted, but by who and why? The stakes are so high in the science world, and The University of Houston is no exception. This story is a real whodunnit and nothing is off the lab table. 

In this episode:

  • Texas Monthly article written by the illustrious Skip Hollingsworth

If you liked this episode please rate, review and subscribe!

Follow us on Instagram: @deadlydosepod

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Email us your homegrown poison stories at deadlydosepod@gmail.com

 

 

 

See omnystudio.com/listener for privacy information.

29 Jun 2022Ep 77 - Drops of Knowledge00:49:32

In the late summer of 1976, a mysterious disease swept through the Bellevue-Stratford Hotel in Philadelphia, Pennsylvania. Hundreds of members of the American Legion, which was holding its annual convention within the Bellevue-Stratford, and several unaffiliated civilians fell ill. The disease took 29 lives. The outbreak was an epidemiological mystery that stumped the CDC for months. What was causing these illnesses and where in the hotel was it coming from? Join us in Epidemiology 101 as Harini details the discovery of Legionnaire’s Disease. 

If you liked this episode please rate, review and subscribe!

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Email us your homegrown poison stories at deadlydosepod@gmail.com

 

Episode Sources:

  • Image 1: From left to right - The Bellvue Stratford Hotel, Legionella bacteria, CDC toxicology team investigating the outbreak (via PhillyMag) 
  • Image 2: A Chest X-Ray of a patient with Legionnaire’s Disease with lungs like a “brillo pad” (via Special Pathogens Lab)
  • Image 3: A veteran in the hospital with a mysterious disease (via The Washington Post)
  • Forensic Files Season 1 Episode 7 
  • https://www.osha.gov/legionnaires-disease
  • https://www.ncbi.nlm.nih.gov/books/NBK7619/
  • Medical Microbiology 4th Edition - Chapter 40 on Legionella 

See omnystudio.com/listener for privacy information.

08 Mar 2023Ep 110 - Chemotherapy: A Life-Saving Treatment Born from a WWII Conspiracy00:42:51

Happy International Women's Day! If you're looking to learn about a rockstar woman scientist, check out Episode 40 - The Mirror Image Disaster. In it, we talk about Dr. Frances Oldhem Kelsey, the FDA scientist who single-handedly fought to keep Thalidomide off the market and out of our medicine cabinets.

In today's episode, Harini teaches Megan about how one of the biggest Allied cover-ups in WWII history led to the discovery and development of chemotherapy. During WWII, German bombers devastated the port of Bari, Italy where Allied personnel were stationed. Soldiers who were launched into the harbor, but survived the bombing, began to experience severe blistering and heightened internal temperatures. American doctor and chemical warfare expert, Stewart Francis Alexander, believed that all symptoms pointed to mustard gas. But when his report to Allied leaders was met with indifference and exasperation, he knew he had stumbled upon a possible conspiracy. Why were they denying the presence of mustard gas in the bay? Why was this form of gas causing these specific symptoms? Tune in to find out.

See omnystudio.com/listener for privacy information.

15 Jun 2022Ep 75 - Dropping like Flies00:47:00

Amid the latest technology and scientific innovations in the modern world that allow us to swiftly catch and convict criminals - there is one seemingly archaic methodology that clearly still remains supreme. With only about a dozen specialists in the United States, forensic entomology is still a relatively new field of forensic science, but it is damn useful. Dropping like flies is an ironic phrase when in reality, flies are bringing new life to cold cases & solving what both machines & humans couldn’t. 

 

If you liked this episode please rate, review and subscribe!

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See omnystudio.com/listener for privacy information.

15 Dec 2021Ep 52 - Street Cleaning01:04:04

It's street cleaning day poison pals and the darkest kind of street cleaning. We're talking all about the 2018 Fentanyl overdosing cases in San Diego. This story hits close to home, so we're bringing out all the PSA's on this one. We answer all questions on the San Diego drug party scene - what's fact, what's fiction, and what isn't widely known.

If you liked this episode please rate, review and subscribe!
Follow us on Instagram: @thatshitispoison

Email us your homegrown poison stories at thatshitispoison@gmail.com

Follow us on Twitter: @thatshitspoison

Follow us on Tiktok: @thatshitispoison 

See omnystudio.com/listener for privacy information.

15 Mar 2023Ep 111 - Mushroom Minisode: Death Cap for Cutie00:26:25

In today's episode, Megan gives a quick mycology lesson on the most poisonous mushroom in the world: the DEATH CAP. Equipped with a toxin that inhibits DNA transcription, and whose only antidote (in extreme cases) is a liver transplant, this mushy is truly as metal as it's name. 

See omnystudio.com/listener for privacy information.

09 Feb 2023Ep 106 - Mystery Meat: An FDA Origin Story01:05:19

This is the epic story of Dr. Harvey Washington Wiley, an American chemist who pulled back the curtain on the unregulated, U.S. food industry of the late 1800s. With the assistance of his "Poison Squad" - a group of test subjects who willingly volunteered to eat food preserved with toxic substances such as formaldehyde and borax - and the indirect help of Upton Sinclair's sensational The Jungle, Harvey was finally able to influence the passing of the Meat Inspection Act and the Pure Food and Drug Act of 1906. Try not to listen on an empty stomach, because you may not have an appetite by the end. 

See omnystudio.com/listener for privacy information.

23 Mar 2022Ep 64 - OxyCoffin Part 301:24:58

Who would ever think that a beautiful red flower could lead to a global epidemic that kills people every minute of every day? Harini dives deep with a three-part series on the history of opium, the start of the modern epidemic with Oxycontin, Purdue Pharma, and the Sackler family. Everything you ever wanted to know about opioids and the epidemic is going to be told to you right now. 

In this episode:

Dopesick (TV series on Hulu)

Crime of the Century (Docuseries on HBO Max) 

If you liked this episode please rate, review and subscribe!

Follow us on Instagram: @deadlydosepod

TikTok: @tilscience

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See omnystudio.com/listener for privacy information.

14 Dec 2022The Deadly Dose Celebrates 100 Episodes!00:56:35

Today we are celebrating our 100th episode! Join us as we reminisce on our favorite episodes and test each other's knowledge in a game of Deadly Dose trivia! We want to give a big, BIG "thank you" to all of the Poison Pals out there who have inspired us to keep creating and sharing these crazy, wonderful stories about science and poison. We could not have done it without you. Cheers to 100!

See omnystudio.com/listener for privacy information.

20 Jan 2023Ep 103 - (Don't) Take Your Vitamins!01:04:18

In this episode, Harini gives us a rundown of the history of vitamins and supplements. An unexpected byproduct of post-WWII, high-yield agricultural practices and the development of genetically modified, disease-resistant grains, supplements and supplemental vitamins quickly became a household staple to accommodate for nutrient-poor food. In less than a century, the world of "vits" and "sups" has evolved into a multi-billion dollar, unregulated industry. The FDA has no jurisdiction here. While the chance of supplement-poisoning is exceedingly rare, listeners will walk away from this episode raising eyebrows every time someone says, "Take your vitamins!".

See omnystudio.com/listener for privacy information.

22 Sep 2021Ep 42 - The Radioactive Russian01:08:36

Picture this, it's 2006, Chris Brown is playing on your iPod nano, and across the pond, in London, England a Russian man is being assassinated with the deadliest element on the periodic table. It's Harini's turn this week to story it up and it is a toxin that was used once and was never used again. This is the assassination of Alexander Litvinenko poison pals. 

In this episode:

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See omnystudio.com/listener for privacy information.

07 Jul 2021Ep 32 - The Three Rotor Problem01:02:15

Codebreaking, computers, and chemicals are what this episode is all about. In honor of Pride month (episode recorded in June), Harini tells the story of the genius mathematician and brilliant cryptologist, Alan Turing, who effectively helped end WWII. Unfortunately, at the time, being gay was a criminal offense with a very toxic punishment. For the vast majority of our lives, the stories of the LGBTQ+ community have been quieted or silenced altogether. Let's do our part to shout their stories from the rooftops now.

 

In this episode:

  • The Imitation Game (movie)

  • Bletchley Circle (TV show) on Netflix

 

If you liked this episode please rate, review and subscribe!

Follow us on Instagram: @deadlydosepod

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Email us your homegrown poison stories at deadlydosepod@gmail.com

 

Episode Sources:

  • Image 1: Alan Turing, a brilliant mathematician, and cryptologist, AND gay during a time when that was absolutely forbidden (via Britannica)

  • Image 2: Alan Turing working on the “Turing Machine” which cracked the Nazi U-submarine codes to effectively end the war (via Phys.org)

  • Image 3: The Turing Machine a.k.a the first computer (via Sutori)

  • https://en.wikipedia.org/wiki/Alan_Turing

  • https://www.nytimes.com/2019/06/05/obituaries/alan-turing-overlooked.html

  • https://www.pbs.org/newshour/science/8-things-didnt-know-alan-turing

  • https://www.turing.org.uk/

  • https://www.iwm.org.uk/history/how-alan-turing-cracked-the-enigma-code

  • https://www.bbc.com/news/technology-18419691

See omnystudio.com/listener for privacy information.

26 Oct 2022Spooktober Special: Bloody Mary00:52:49

We wish this episode was about the best breakfast cocktail ever, but alas, it is not. In our final installment of our Spooktober Series, Megan talks about the origins of the most infamous urban legend that plagues slumber parties and tween girls everywhere. Who is Bloody Mary and why is the act of summoning her of particular fascination to children? Is this spooky folktale a bizarre euphemism for puberty or is it just paranormal fun and games? If you stick around long enough, you'll get to witness Megan perform the ritual herself. WARNING: panic definitely ensues. 

If you liked this episode please rate, review and subscribe!

Follow us on Instagram: @deadlydosepod

TikTok: @tilscience

Email us your homegrown poison stories at deadlydosepod@gmail.com

See omnystudio.com/listener for privacy information.

26 Jan 2022Ep 56 - Beware the Ice Man01:32:36

Do you know the Ice Man? Rumored to have killed over 100 people for the sheer thrill of it, with varying methods, which made him hard to catch. He was the mixed-media of serial killers if you will (excuse the poor humor). This story is anything but straightforward, so Megan is going to walk you through it step by step. But, grab your blankets and huddle in close to listen because the Ice Man is coming...

In this episode:

The Ice Man Series on HBO 

If you liked this episode please rate, review and subscribe!

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22 Dec 2021Ep 53 - The Red Queen Hypothesis01:21:25

Poison pals it's the LAST episode of the year and we're ending on a banger. We are SO delighted to have Dillon Jones aka @dillonthebiologist on IG. He is San Diego's finest frog enthusiast and science communication expert on all things reptiles and amphibians. Dillon talks to us about poison dart frogs, how they evolved their jewel-toned colors and the psychedelic toads of the world. This was truly one of the most fun recordings we've done to date, so don't miss out on our conversation with Dillon Jones the Biologist. We'll see you in 2022 poison pals! 

In this episode:

Dillon Jones on IG @dillonthebiologist 

Website: https://withkoji.com/@DillonTheBiologist

 

If you liked this episode please rate, review and subscribe!

Follow us on Instagram: @deadlydosepod

TikTok: @tilscience

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See omnystudio.com/listener for privacy information.

19 May 2021Ep 25 - Barber in the Streets, Poisoner in the Sheets!01:37:24

What do 19th century Victorian-era London, barbers & surgeons, Jack the Ripper, and a lot of booze have in common? THIS EPISODE. Come one, come all poison pals! Sit yourself down with your finest cuppa Earl Grey, nan's biscuits, and gather by the hearth for warmth as this is a cold-blooded trifecta of poison. Megan tells the three-part tale of George Chapman - the serial poisoner of the 19th century.

In this episode:

  • The Elements of Murder: A History of Poison by John Emsley

 

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Episode Sources:

  • Image 1: George Chapman (birth name Seweryn Klosowski) circa 1880s

  • Elements of Murder: A History of Poison by John Emsley (2005)

See omnystudio.com/listener for privacy information.

16 Feb 2022Ep 59 - Justice Delayed is Justice Denied01:24:48

We're getting straight to the point today. Today is a joint effort to tell the tragic story of Lauren Smith-Fields. If you know who Gabby Petito is, then you need to know who Lauren Smith-Fields is as well. But, this story goes even deeper - we talk about the historical and societal reasons why people of color are consistently given inadequate and disparate treatment by the law and law enforcement going all the way back to the birth of the United States. This is a heavy one poison pals, but it is a MUST listen. 

In this episode:

@_lyneezy on Instagram: https://www.instagram.com/tv/CZSZL2bjIw4/?utm_source=ig_web_copy_link

Naloxone Resources: https://www.samhsa.gov/medication-assisted-treatment/medications-counseling-related-conditions/naloxone

Beforeigners (TV series) on HBO Max 

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01 Dec 2021Ep 50 - Behind Closed Doors...01:27:52

Hello listener, in today's episode, you'll be asked to participate. The facts will be relayed to you in this whodunnit case and YOU are juror #12. Can you provide a fair and balanced verdict?

This case is about neighbors. How well do you know them or think you know them? Clearly not well enough. 

In this episode:

  • Rear Window (film) 
  • Texas Monthly - Killer Next door (article) 

If you liked this episode please rate, review and subscribe!

Follow us on Instagram: @deadlydosepod

TikTok: @tilscience

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See omnystudio.com/listener for privacy information.

13 Jul 2023Ep 120 - The Freedom House Ambulance Service00:57:21

In today's episode, Harini shares the incredible story of The Freedom House Ambulance Service. Freedom House was the first emergency medical service in the United States to provide training beyond first aid and other amazing things, such as being the first emergency service to supply Narcan in overdose cases! Freedom House, staffed entirely by black paramedics, was the blueprint for paramedic training and emergency medical services today (although back then, a ride in the ambulance was entirely free *sigh*).

Further Reading: "American Sirens" by Kevin Hazzard. 

See omnystudio.com/listener for privacy information.

13 Jul 2022Ep 79 - Don't Drink the Kool-Aid!00:58:55

REWIND: in honor of our new chapter as The Deadly Dose, we are re-recording some of our old, but gold episodes starting with our original Ep. 2. Harini takes you back in time with her and to Jonestown, Guyana to share the infamous tale of Reverend Jim Jones and The People's Temple cult. You can listen, but whatever you do, just don't drink the Kool-Aid!

 

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In this episode

  • The Secret (book) 
  • The Unexplained (Netflix series) 

Episode Sources:

  • Kansas City Public Library
  • Britannica article by Alison Eldridge
  • Wikipedia
  • The Legacy of Jonestown by Eric Banks from the Wall Street Journal
  • PBS article the American Experience
  • FBI.gov on Jonestown
  • The Unexplained show on Netflix

See omnystudio.com/listener for privacy information.

16 Feb 2023Ep 107 - The Toxic Lady01:02:42

In Riverside, CA, 1994, a young woman by the name of Gloria Cecilia Ramirez was admitted to the emergency department of Riverside General Hospital for tachycardia and abnormal respiratory patterns. As emergency staff proceeded with defribillation, it was observed that Gloria's body was covered in an oily sheen and was emitting a garlicky-fruity smell. As a nurse drew blood, the smell of ammonia filled the room. Several hospital workers in proximity to Gloria became nauseaus and collapsed. What was happening in that hospital room? Had Gloria's body become a biomedical hazard? And, if so, how? This is the story of The Toxic Lady. 

See omnystudio.com/listener for privacy information.

11 Aug 2021Ep 37 - The Lethal Lassi00:55:18

Remember that one time you ordered from your favorite Indian joint down the road and you got a creamy, delicious, mango lassi? Well, this story is exactly like that. Except it takes place in Pakistan, there’s an arranged marriage, and the lassi is spiked with poison. In honor of Harini’s upcoming wedding, Megan tells the story of a defiant bride whose plot to poison her betrothed goes drastically awry when the whole wedding party falls ill due to a tampered batch of lassi.

 

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Episode Sources:

  • Image 1: A tray of lassi, similar to the batch that Aasia Bibi laced with rat poison before her arranged wedding to her cousin.

  • Image 2: Aasia Bibi and her alleged boyfriend Muhammad Shahid (in the black hood) after their arrest.

  • https://www.washingtonpost.com/news/morning-mix/wp/2017/11/02/pakistani-bride-kills-17-people-with-poison-milk-to-escape-arranged-marriage/

  • https://www.npr.org/sections/thetwo-way/2017/11/02/561589498/pakistani-bride-charged-with-poisoning-husbands-milk-inadvertently-killing-17

  • https://www.nytimes.com/2017/11/03/world/asia/pakistan-newlywed-poison.html

  • https://www.bbc.com/news/world-asia-41816049

  • https://apnews.com/article/pakistan-middle-east-international-news-asia-pacific-arrests-62ed09dce0744f7380b0ef61c28fa0b3

See omnystudio.com/listener for privacy information.

23 Feb 2022Ep 60 - Down by the Minamata Bay (Part 1)00:52:02

Cat dancing fever, big corporation, Japan, and, of course, poisoning are the big themes of today's episode. A decades-long pollution poisoning went unnoticed for so long in Minamata, Japan, but Megan is here to give you the full story. Megan is making pod history by doing her first 2 parter - so DON'T miss out!

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21 Jul 2022(Encore) Ep 80 - Sweet Dorothea01:03:02

In this episode, Megan pays homage to her home city of Sacramento, CA by detailing the life and crimes of the serial poisoner, Dorothea Puente. Puente came to notoriety in the late 1980s when a welfare check-up on a missing tenant led to the discovery of seven bodies in her yard, thus christening her home as the infamous Murder House in Sacramento. How did this “feeble old woman” (as the media would have you believe) commit such sinister misdeeds? Tune in to find out!

 

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Episode Sources:

See omnystudio.com/listener for privacy information.

18 May 2022Ep 72 - Jim v. Rattlesnake01:04:17

With summer on the horizon, all of us are coming out of the woodwork to bask in the sun, including rattlesnakes. In this episode, Harini retells an episode of "I Survived" where a man in the foothills of the Smoky Mountains is picking blueberries under a warm spring sun when he encounters an unwanted surprise... Keep your wits about you when listening to this episode!

In this episode:

  • I Survived S5E23 

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15 Jun 2021Ep 29 - A Doctor a Day...01:19:25

In this episode, Megan talks about the death of five-year-old Garnett Spears whose mother, Lacey Spears, incrementally poisoned him with table salt. We warn that this episode is mildly graphic and extremely uncomfortable as it details the ongoing torture of a young child, typical of similar cases that involve Factitious Disorder Imposed on Another (formerly known as Munchausen syndrome by proxy).

 

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Episode Sources:

  • Image 1: An infant Garnett smiling with his mother, Lacey.

  • Image 2: Lacey and Garnett cuddling together.

  • Image 3: A still image of Garnett and Lacey in the ICU after a mysterious bout of intense illness and seizures.

  • Image 4: A still image of the last recorded video of Garnett in the ICU moments before Lacey administers a final, lethal dose of salt into his G tube.

  • Image 5: Lacey on trial for the murder of her son in 2015.

  • https://www.washingtonpost.com/news/morning-mix/wp/2014/06/18/woman-pleads-not-guilty-to-poisoning-her-5-year-old-son-to-death/

  • https://truecrimedaily.com/2016/12/08/mom-caught-on-camera-poisoning-young-son-to-death-in-hospital/

  • https://www.usatoday.com/story/news/nation/2015/04/08/lacey-spears-to-be-sentenced-today-in-sons-death/25446521/

  • https://www.lohud.com/story/news/investigations/2014/06/17/lacey-spears-murder-charges-garnett-spears/10665173/

  • https://www.lohud.com/story/news/local/rockland/2014/03/24/garnett-spears-feeding-tube-life/6855849/

  • https://www.lohud.com/story/news/investigations/2014/06/18/lacey-spears-investigated-abuse/10750237/

  • https://www.mdpi.com/2072-6643/9/7/648

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915702/#:~:text=Factitious%20Disorder%20Imposed%20on%20Another,make%20her%20child%20appear%20sick.

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537768/

  • https://www.sciencedirect.com/science/article/abs/pii/S037907380300358X

See omnystudio.com/listener for privacy information.

12 May 2021Ep 24 - The Slender Woody Climber (In Defense of Plants Crossover)00:47:48

Calling all plant people, this episode is for you! We are doing our very FIRST crossover episode with the evergreen Matt Candeis of the In Defense of Plants podcast, blog, and now BOOK! We couldn't be more excited to put our minds together to bring you an episode all about the deadliest plant in the world - Abrus precatorius, also known as, the Rosary Pea. Praying with your rosary beads isn't going to save you this time! 

In this episode:

  • Matt Candeis of In Defense of Plants podcast 

  • @indefenseofplants on Instagram

  • Blog: https://www.indefenseofplants.com/

  • Book: In Defense of Plants: An Exploration into the Wonder of Plants

  • Matt's antidote of the week: the incredible findings by the lovely Cariad Williams, Ph.D. student at the University of Illinois, on the flight mechanism of Pterosaurs. Check it out below!

  • https://www.nytimes.com/2021/04/14/science/pterosaurs-necks-azhdarchids.html?smid=url-share

 

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Episode Sources:

  • Image 1: Rosary Pea (via The Survival Gardener)

  • https://www.poison.org/articles/are-rosary-peas-poisonous-194#:~:text=The%20entire%20plant%20is%20toxic,%2C%20abdominal%20pain%2C%20and%20diarrhea.

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672262/

  • https://missouripoisoncenter.org/is-this-a-poison/rosary-peas/

See omnystudio.com/listener for privacy information.

30 Jun 2021Ep 31 - Come Hell or High Water!01:11:13

Do you know what's in the water you're drinking? The ocean you just swam in and perhaps took an accidental big gulp of water from? The lake that your dog just drank out of? Most people don't, so that's why environmental toxicologist and PhD candidate, Allie Folcik, is going to give us the filtered tea! This was one of our favorite episodes to record, you don't want to miss it, poison pals!

In this episode:

  • Check out Allie's highly successful science & fashion blog called The Pretty PhD: https://prettyphdblog.com/

  • Follow her on Instagram @theprettyphd and on TikTok with the same handle!

  • Troubled Water (2012 Documentary) - YouTube

  • The Bobby Bones Show

 

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Episode Sources:

  • Image 1: The extremely old lead pipes that are the majority of the US’s water pipes (via Materials Science)

  • Image 2: The water in Flint Michigan vs typically treated water (via Blackbottom Archives)

See omnystudio.com/listener for privacy information.

03 Nov 2021Ep 47 - Door Locking Freaks01:21:45

Our Spooktober series is officially coming to an end with our fourth and final installment. Do you believe in premonitions, in intuition, in angels or spirit guides? Have you ever followed a strong gut feeling that turned out to be right? This episode is all about near-death experiences and near misses. 

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24 Nov 2022Ep 98 - The Stingray Shuffle Hustle01:22:22

In this episode, Megan takes us on an underwater adventure to swim alongside the magnificent and often misunderstood stingray! Megan even shares her own personal experience of being stung by one of these silly water pancakes, the traumatic event that inspired this episode! So don't hit that shuffle button just yet. The only shuffling we're doing today is the Stingray Shuffle. 

In today's episode, Harini provides a play-by-play of The Good Nurse, Netflix's recent true-crime biopic that details the harrowing story of nurse Amy Loughren who became a confidential informant for the New Jersey Police Department in their efforts to catch serial killer Charles Cullen. Cullen was a nurse who moved discreetly within the healthcare industry for 16 years before being caught for poisoning and murdering patients. As Part I, this episode will cover the film adaptation of this incredible story. Stay tuned for Part II which will shed more light on the events that occurred in real life. 

Sources:

 

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12 Jan 2023Ep 102 - Permafrost: What Lies Beneath?00:35:07

In this episode, Harini explains the importance of permafrost and how this frozen slurry of soil, rocks, and sand is the guardian of millennia-old bacteria, fungi, and viruses! Permafrost has become a greater topic of public interest as concerns around climate change and the reduction of our greater carbon footprint have intensified within the last decade. Is the permafrost melting and, if so, how fast? And what mysteries of the deep are finally coming to surface?

See omnystudio.com/listener for privacy information.

06 Oct 2021Ep 44 - Saved by the Bell!01:08:11

IT'S SPOOKY SEASON! Harini is kicking off our Spootkober series with a dead ringer this week. What if your last breath was only an illusion? What if your family, your friends, the coroner even, all thought you were dead, so they bury you...alive. Your only hope now is to be saved by the bell.

In this episode:

  • Westworld (TV series)
  • Master & Commander (film)
  • Motherland (TV series)

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09 Nov 2022Ep 96 - Waves of Pain00:46:51
05 Apr 2023Ep 112 - Lizard Lips and Sunken Cheeks: Demystifying Ozempic00:59:24

In today's episode, Harini and Megan discuss the recent pop-culture fascination in weight loss drugs. Specifically Ozempic, Wegovy, and generic semaglutide. What are these drugs, what do they do, and why have they (allegedly) taken the celebrity world by storm? Are these drugs legitimately controversial or has the online zeitgeist created artificial contention? We have answers. 

See omnystudio.com/listener for privacy information.

13 Apr 2022Ep 67 - Cannaba Cannadioid00:54:18

Weed gummy bears, brownies, and candy bars come in the most beautiful, colorful packaging - so appealing that more toddlers than ever are getting into their parents' weed stash. Megan discusses the rise in cannabis intoxication in children. 

In this episode:

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16 Mar 2022Ep 63 - OxyCoffin Part 201:04:16

Who would ever think that a beautiful red flower could lead to a global epidemic that kills people every minute of every day? Harini dives deep with a three part series on the history of opium, the start of the modern epidemic with Oxycontin, Purdue Pharma, and the Sackler family. Everything you ever wanted to know about opioids and the epidemic is going to be told to you right now. 

In this episode:

Dopesick (TV series on Hulu)

Crime of the Century (Docuseries on HBO Max) 

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05 May 2021Ep 23 - Tough Titties Part II01:08:36

We teased this in the first episode of The Deadly Dose and now it is finally coming to fruition. This episode contains fanatic Indian religious groups, Oregon, beer, sex, a villainous, but BOSS businesswoman, and poison. What more could you want in a story? Join us as Harini takes on the behemoth tale of the Bhagwan Shree Rajneesh and Rajneeshpuram. Pro tip: burn all your maroon clothing before listening. 

In this episode:

  • Searching for Sheela (2021 series) on Netflix

  • Wild Wild Country (series) on Netflix

  • Bat Shit Valley by Documentary Now (a spoof on Wild Wild Country) on Netflix

 

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Episode Sources:

  • Image 1: Sheela displaying her simultaneous sharp business acumen and ruthlessness (via Netflix)

  • Image 2: Bhagwan addressing his countless followers (via Hindustani Times)

  • https://www.theatlantic.com/politics/archive/2014/06/a-strange-but-true-tale-of-voter-fraud-and-bioterrorism/372445/

  • https://www.cdc.gov/phlp/docs/forensic_epidemiology/Additional%20Materials/Articles/Torok%20et%20al.pdf

  • https://www.latimes.com/archives/la-xpm-1985-11-01-mn-825-story.html

  • https://www.ncbi.nlm.nih.gov/books/NBK482160/

  • https://pubchem.ncbi.nlm.nih.gov/compound/Epinephrine

  • CDC

See omnystudio.com/listener for privacy information.

21 Sep 2022Ep 89 - Jordan Peterson and Benzos01:18:20

In the last six years, Jordan Peterson has become one of the most polarizing public intellectuals to grace mainstream news outlets. At the peak of his ascent to sociopolitical celebrity, he fell off the face of the Earth. After a year of silence, he returned to his Youtube fanbase (with the help of his daughter) to share his story of battling benzodiazepine addiction and withdrawals. His recollection of his year-long rehabilitation and choices in detox treatments have been deemed controversial by drug experts and healthcare practitioners. All in all, we figured his story would be a great introduction to benzos, and what someone should be aware of when seeking a benzo prescription. 

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Episode Sources:

 

 

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25 Aug 2021Ep 39 - The Poisoner's Poison01:20:17

There’s one poison out there that is so idyllic and covert in its mechanism of action that it has been deemed “the poisoner’s poison”. It is colorless, odorless, tasteless, and takes weeks for a victim to become symptomatic, giving the culprit ample time to distance themselves from the scene of the crime. Even then, its effects mimic countless diseases and even other poisons. Its name? Thallium. And the best way to introduce this notorious poison is by way of Graham Young, aka the Teacup Poisoner, whose secret ingredient for every cuppa he served was just a dash of this insidious heavy metal.

 

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Episode Sources:

  • Image 1: mugshot of Graham Young after his final arrest for murdering two colleagues and poisoning many more.

  • Image 2: A teenaged Graham Young being escorted to Broadmoor Hospital.

  • The Elements of Murder: A History of Poison by John Emsley.

See omnystudio.com/listener for privacy information.

17 Nov 2021Ep 49 - We Didn't Start the Fire01:04:36

If there is an episode we would hope you listened to, it's this one. Veteran's Day just passed and how often do we say, "Thank you for your service!"

After today's episode, I hope we all think about that phrase in a different light and start or continue to do our part to advocate for our Veterans. So, today we're talking about burn pits. You probably haven't heard of burn pits and that's not on accident.  Megan raises awareness about the horrors of burn pits and the silence that has surrounded burn pits for almost 20 years. 

 

In this episode:

Non-Profit Veteran Advocacy Group

VA Burn Pit Registry

Resources to Understand and Track Senate Bill 952- Presumptive Benefits for War Fighters Exposed to Burn Pits and Other Toxins Act

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28 Jul 2021Ep 35 - A Silly Bet on an Ugly Beetle!01:00:34

In this episode, Megan debunks the mythologies surrounding a very sultry poison. Beloved as an innuendo in sitcoms and raunchy comedies, cantharidin, aka Spanish Fly, has gained a reputation as an aphrodisiac/love potion. Be warned: Spanish Fly, a misnomer, is actually derived from the blister beetle. Can you guess why it’s called the blister beetle? Let’s just say that using Spanish Fly as an aphrodisiac has a low chance of spicing up your love life, but a very high chance of spicing up your insides…to the point of internal organ damage. Mutilated genitals anyone?

In this episode:

Spanish Fly Cocktail Recipe:

  • 1 oz tequila (Jose Cuerva)
  • 1 oz rum (Bacardi 151)
  • 1 oz Kahula 
  • Rich black coffee (as much as your heart desires)
  • Whipped cream (as much as your heart desires)
  • Cherry on top! 

 

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Episode Sources:

  • Image 1: Blister beetles are beetles of the family Meloidae, so called for their defensive secretion of a blistering agent, cantharidin.

  • Image 2: An advertisement for Spanish Fly as an aphrodisiac.

  • Image 3: A fresco depicting Greek fertility god, Priapus, the inspiration for the medical term “priapism”. If you’d like to see the un-blurred version, search “Priapism” on wikipedia.

  • https://jamanetwork.com/journals/jamadermatology/fullarticle/478535

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432444/

  • Whitman, D. et al. (2019) Antiparasitic Properties of Cantharidin and the Blister Beetle Berberomeloe majalis (Coleoptera: Meloidae). Toxins

See omnystudio.com/listener for privacy information.

06 Apr 2022Ep 66 - A Dance with Death00:53:30

POV: you are a young woman in the Victorian era and you just bought the most beautiful green dress for the masquerade ball this Friday. Very Bridgerton vibes.

Throw away those rose-colored glasses, and put on your green-colored glasses. Actually, you have no choice in the matter because you have arsenic poisoning from the dress you're wearing. Your skin is green, your fluids are green, and all you see is green. 

 

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02 Jun 2021Ep 27 - To Kambo or Not To Kambo00:59:09

DISCLAIMER

All discussions in this episode are our own opinions and not facts outside of the science and background presented. 

In this episode, Megan talks about the practice of Kambo, an ancient South American tradition of cleansing/purging the body with toxic secretions derived from the Giant Leaf frog. Having found its way into Silicon Valley as the next trending homeopathic medicine (move aside micro-dosing) we ask the question: how appropriate is it to use these culturally sacred practices outside of the tribes from which they originated?

In this episode:

  • Alone: Orphaned on the Ocean by Tere Fassbender and Richard D. Logan

  • My Next Guest with David Letterman (Lizzo episode) on Netflix

  • Grantchester (TV series) on Acorn TV

 

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Episode Sources:

  • Image 1: Phyllomedusa bicolor aka the giant leaf frog contains the toxic secretion used in Kambo ceremonies. The secretions carry unique opioid peptides called deltorphins (which do not occur naturally in any other species) and demorphin.

  • Image 2: Secretions being collected from a live giant leaf frog. It’s legs are bound in order to induce the release of Kambo from it’s skin - a reaction that occurs only when the giant leaf frog feels stressed or threatened.

  • Image 3: An indigenous Matses healer prepares to place Kambo onto a participant.

  • Image 4: Kambo mucous being scraped onto a medicine stick.

  • Image 5: Burn marks on a patient’s arm shaped in a line 4-5 burns deep, typical of a Kambo cleansing ritual.

  • https://amazonexplorer.com/culture-of-indigenous-matses-people-the-frog-medicine-kambo/

  • https://www.tandfonline.com/doi/abs/10.1080/15563650.2018.1457153

  • https://onlinelibrary.wiley.com/doi/abs/10.1111/1556-4029.13641

  • https://www.sciencedirect.com/science/article/pii/S2214750022000865

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284396/

  • https://clinmedjournals.org/articles/iacp/international-archives-of-clinical-pharmacology-iacp-4-017.php?jid=iacp

  • https://www.insider.com/silicon-valley-elites-are-poisoning-themselves-with-kambo-frog-mucus-2021-1

  • https://shamanicsnuff.com/shop/kambo/kambo-sticks/

  • https://www.vice.com/en/article/gqkxa9/kambo-ceremony-alcoholism-purging-uk

  • https://www.nytimes.com/2021/01/01/style/self-care/kambo-tree-frog-detox.html?referringSource=articleShare

See omnystudio.com/listener for privacy information.

30 Mar 2022Ep 65 - Recap (Burn Pits, Lauren-Smith Fields, Sunny Balwani)00:34:23

With 66 episodes and counting, we thought it was time for an update on past episodes that may not have been fully fleshed out or resolved at the time we recorded them. Megan takes us through 3 past stories and gives us an update on what's happened and what's to come. 

In this episode:

Burn Pits:

https://www.militarytimes.com/news/burn-pits/2022/03/08/biden-vows-action-not-waiting-for-veterans-suffering-from-burn-pit-illnesses/

Brenda Lee Rawls:

https://www.ctpost.com/news/article/Bridgeport-police-release-cause-of-death-for-16938935.php

Sunny Balwani Trial:

https://www.nytimes.com/2022/03/22/technology/theranos-trial-balwani.html

 

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17 Aug 2022(Encore) Ep 84 - MK-Ultra Part II, Would You Like Some Cointreau With That LSD?00:53:43

It’s a Deadly Dose re-release, Part II! We’re bringing back Harini’s coverage of MK-Ultra and all the questionable, unsanctioned sh*t that occurred under this infamous CIA mind-control program. One conspiracy of significance that came of MK-Ultra was the untimely and mysterious death of American bacteriologist, Frank Olson. Pour yourself some Cointreau (sans LSD - unless, you know, that's your thing) and settle into this mid-century thriller of espionage, conspiracy, murder and drugs. 

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In this episode:

  • Wormwood on Netflix (a docuseries about Frank Olson's death and MK Ultra)

Sources:

See omnystudio.com/listener for privacy information.

20 Oct 2021Ep 46 - Don't Look Up.01:00:20

It's the third installment in the Spooktober series and it's back to Harini to tell us a spooky tale. This episode features a very special guest, Harini's husband, Dev, and his firsthand encounter with a ghost in India. That's right, this episode is all about ghosts, demons, and folklore from South Asia. Listen at night if you dare, but whatever you do...don't.look.up. 

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02 Feb 2023Ep 105 - Yokkaichi Asthma00:45:24

We're rounding out the Four Big Pollution Disasters/Diseases of Japan with Yokkaichi asthma. Yokkaichi asthma was the name given to a breadth of respiratory ailments that the people of Yokkaichi, Japan suffered due to negligent industrial plant practices between 1960-1970. Sodium dioxide and sodium trioxide (in the form of acid mist) filled the skies above Yokkaichi and left a lasting impact on the city. Similar to Minamata and Itai Itai disease, Yokkaichi asthma was a result of a rapidly industrializing country that was laser focused on its chemical exports, sadly, to the detriment of its environment and its people.  

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06 Oct 2022Spooktober Special: Vampyres!00:56:52

Spooktober is officially here! In our first installment of our annual Spooktober series, we're talking all about Vampyres. To this day, we still celebrate the seductive, undying, Euro-centric interpretation of vampires in our media, literature, and costumes despite being a centuries-old trope. What is the history and science behind the mythology that we love? Were vampires ever real or was there a misunderstood virus involved at the root of vampire lore? Take a bite of this episode to find out!

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01 Jun 2022Ep 74 - Glamping Gone Wrong00:50:45

POV: the sun is radiating down on you, warming your skin while you trek through a large expanse of meadow. To your right is the majestic monolith of El Capitan and overhead you hear the birds singing their morning songs to one another. At the end of the evening, you come home to the luxury of your glamping site and snuggle into bed with the warmth of blankets around you and a soft pillow to rest your head. But, little do you know that something sinister lurks beneath the wooden floorboards of your glamping tent, ready to feast on its new prey...

In this episode:

  • Ted Lasso (Apple TV)
  • Better Call Saul (Netflix Series) 

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12 Jan 2022Ep 54 - It's Elementary My Dear (Part 1)01:14:20

Welcome back poison pals to the first episode of 2022. This is as current as it gets with this story of power, (misplaced) ambition, money, deceit, and, of course, blood.

Harini tells the story of Elizabeth Holmes, the tech giant who fell from grace along with her once visionary company called Theranos. This isn't the story you heard so many times through the documentaries - we go deep to the root of what went down. Join us poison pals on this rollercoaster of a story.  

In this episode:

The Inventor (HBO Max)

Bad Blood: Secrets and Lies in a Silicon Valley Startup by John Carreyrou  

American Scandal Podcast on Theranos 

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26 Jan 2023Ep 104 - Itai Itai00:37:52

Harini is launching a YouTube channel! Today I Learned Science by Dr. Harini Bhat goes live on Thursday, January 26th at 12pm PST. Click the link below and subscribe for additional, riveting science content that goes beyond the world of toxicology and poison. 

https://youtube.com/@tilscience

In this episode, we discuss Itai Itai disease -  one of the Four Big Pollution Diseases of Japan. Similar to Minamata disease, this excruciating bone and kidney disease was the outcome of mass, toxic metal poisoning through polluted waterways. It disproportionately impacted women and the elderly. Those who became sick were known to weep the phrase "Itai Itai!", meaning "It hurts! It hurts!".

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22 Aug 2022(Encore) Ep 85 - The Ultimate Prank01:14:22

We're back with another Deadly Dose re-release! In this episode, Megan talks about the most incredible poisoning/assassination event to have occurred in the 21st century: the assassination of Kim Jong-nam, half-brother of Supreme Leader of North Korea Kim Jong-un. What starts as an investigation into two women accused as assassins, develops into an unbelievable plot of geopolitical intrigue, an elaborate network of North Korean agents, a deadly nerve toxin, months of orchestration, and two unsuspecting women manipulated by the promise of stardom. 

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In this episode:

  • Assassins - a documentary on Kim Jong Nam's assassination by Ryan White 
  • Harini's current book - Entangled Life: How Fungi Make Our Worlds, Change Our Minds and Shape Our Futures by Melvin Sheldrake 

Episode Sources:

  • GQ: The Untold Story of Kim Jong-nam’s Assassination by Doug Bock Clark (photography by Jesse Chehak)
  • WSJ Video: The Moment Kim Jong am Was attacked: CCTV Footage
  • NPR Asia: North Korean Leader’s Slain Brother was Reportedly Working with the CIA by Scott Neuman
  • WSJ: North Korean Leader’s Slain Half Brother Was a CIA Source by Warren P Strobel

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18 Aug 2021Ep 38 - Mystery of the Mormons01:33:09

Mormons, murder, forensic analysis, forgery, and an art heist are all wrapped up in this one gripping story. Harini tells the story of Mark Hoffman, an expert forger whose increasing ambitions and heightened schemes lead to the murders of two of his fellow Latter Day Saints members. What does this have to do with science? Mark Hoffman's M.O. was explosives and there is a surprising medical history behind dynamite. 

Episode Sources:

  • Image 1: The bombing of Mark Hoffman’s car and what tipped off this entire investigation (via Murderpedia)

  • Image 2: Mark Hoffman and one of his “rare books” (via Oxygen)

  • Murder among the Mormons (Netflix)

  • https://www.nobelprize.org/alfred-nobel/nitroglycerine-and-dynamite/#:~:text=Nitroglycerine%20is%20an%20explosive%20liquid,of%20nitric%20and%20sulphuric%20acid.

  • https://en.wikipedia.org/wiki/Dynamite

  • https://www.heartandstroke.ca/heart-disease/treatments/medications/nitroglycerin

 

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24 May 2023Ep 116 - Golden Geese and Horseshoe Crabs00:39:28

We're back(!)... with a continuation of Harini's coverage of significant Golden Goose Recipients. In today's episode, Harini talks about 2019 Golden Goose awardees, Dr. Jack Levin and Dr. Frederik Bang, who pioneered the Limulus Amebocyte Lysate (LAL) Test by identifying the sterilizing potential of horseshoe crab blood. To this day, the blood of horseshoe crabs is used in pharmaceutical testing to ensure safety during drug development. Harini and Megan talk about these fascinating, living fossils and the potential for synthetic alternatives. 

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09 Mar 2022Ep 62 - Oxycoffin (Part 1)01:25:51

Who would ever think that a beautiful red flower could lead to a global epidemic that kills people every minute of every day? Harini dives deep with a three part series on the history of opium, the start of the modern epidemic with Oxycontin, Purdue Pharma, and the Sackler family. Everything you ever wanted to know about opioids and the epidemic is going to be told to you right now. 

In this episode:

Dopesick (TV series on Hulu)

Crime of the Century (Docuseries on HBO Max) 

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14 Jul 2021Ep 33 - Pied Piper Mouse Seed01:16:43

In this episode, Megan takes us back to the 1800s where literally anything goes, for example, lots and lots of murder by poison! (Is the 1800s the metaphorical equivalent of the 70’s?) Megan tells us the suspiciously sweet story of Christiana Edmunds, aka the Chocolate Cream Poisoner. This episode is a friendly reminder that you should always vet a mysterious box of sweet treats before digging in. If there’s no sender, you might just be biting into a strychnine ganache.

 

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Episode Sources:

  • Image 1: A courtroom sketch of Christiana Edmunds captioned “At the Bar of the Old Bailey, convicted of Poisoning at Brighton.”

  • https://murderpedia.org/female.E/e/edmunds-christiana.htm

  • https://inchem.org/documents/pims/chemical/pim507.htm

  • https://emergency.cdc.gov/agent/strychnine/basics/facts.asp

  • https://www.cdc.gov/niosh/ershdb/emergencyresponsecard_29750018.html

  • https://journals.lww.com/jfmpc/Fulltext/2017/06030/A_rare_case_report_of_Strychnos_nux_vomica.42.aspx

  • https://womenshistorynetwork.org/the-case-of-the-chocolate-cream-killer-the-poisonous-passion-of-christiana-edmunds/

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13 Oct 2021Ep 45 - Sleep Tight Don't Let the Demons Bite01:22:08

You're in bed, tucked snug underneath the covers, and you slip into a dreamless slumber, when all of a sudden you hear a rustle in the corner. Your eyes fly awake and you see something crawling towards your bed...closer...closer...but no matter how hard you try, you can't move your body. The figure is on your bed now, and right when you think it is all over, you wake up. This episode is all about the horrors and science of sleep paralysis. Brace yourselves, poison pals, it's going to be a sleepless night. 

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27 Apr 2022Ep 69 - Unhilled and Unhinged!00:59:04

We just *might* ruin your favorite food on today's episode. When you think of the one vegetable that is a staple in the majority of diets culturally around the world, what vegetable do you think of? The one we gobble up voraciously during Thanksgiving, that forms soft pillows under pasta sauce or douse with ketchup at our local bar? The very humble potato just got a little more sinister...

In this episode:

 

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23 Jun 2021Ep 30 - Father Knows Best!00:29:53

You guys definitely didn't ask for it, but we're thrusting it upon you anyways...

In honor of Father's Day, we thought what better way to celebrate than to have Harini's dad, Papa B, on the pod! We're keeping it short and sweet, but chock full of deadly poison per usual. The category is: Bongkrekic Acid...

 

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Episode Sources:

  • Image 1: Bongkrekic acid is often found in fermented noodles (via Poison Control)

  • Image 2: Bongkrekic acid is also found in tempeh (via Nature’s Poison)

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09 Feb 2022Ep 58 - Always Spaghetti in Philadelphia00:35:28

Let's (mentally) go back to the Depression Era Philadelphia. You're an Italian immigrant who has an ailing husband and you need an elixir to cure your husband. You seek out said elixir from your local apothecary, but your husband isn't cured - he's dead. This is the story of the Philadelphia Poison Ring. 

 

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04 Jan 2023Ep 101 - The Hand of Wetterhahn00:41:09

In our first episode of 2023, Harini introduces us to Dartmouth professor and chemist Karen Wetterhahn, who specialized in toxic metal exposure. In the 1990s, Dr. Wetterhahn was a tour de force in the world of toxic metal research and greatly influenced an increased interest among women to pursue science majors through Dartmouth College's Women in Science Project (WISP). In a cruel twist of fate (or cosmic anomaly), Wetterhahn's career and life ended early doing exactly the thing she loved the most. 

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31 Aug 2022(Encore) Ep 86 - What's Inside Room 239?01:05:57

As the Russia-Ukraine war continues, and global outcry against the Russian Federation's invasion loses it's intensity, we wanted to bring back our coverage of the assassination attempt on Russian opposition leader and anti-corruption activist, Alexei Navalny.

In 2020, Navalny was poisoned with a nerve agent called Novichok. During his recovery, he organized a private investigation unit to uncover his assailants. The investigation implicated FSB agents and Putin himself.

In this encore presentation, we've added additional commentary on Navalny's current status as a prisoner of the Kremlin. 

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 Sources:

See omnystudio.com/listener for privacy information.

22 Jun 2022Ep. 76 – Go to Sleep, Count Some Sheep…01:01:18

Melatonin has become an increasingly popular supplement used by both adults and children. For some children, the ingestion of melatonin is completely accidental. And according to a recent report published by the CDC, accidental pediatric ingestions of melatonin have increased by over 500% in the last decade. In this episode, Megan provides an overview of the CDC’s concerns and the US’s relationship with the extremely popular endogenous hormone/ sleep aid, melatonin.

 

In this episode:

 

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Episode Sources:

See omnystudio.com/listener for privacy information.

11 May 2022Ep 71 - The Eagle has Landed00:37:20

When you are out in the wild, one of the rare pleasures in life is to see an animal in its natural habitat. Especially when that animal is our national bird, the bald eagle. Bald eagles are making the front page and not in a good way, unfortunately. More than 50% of the bald eagle population is poisoned with lead and we're diving deep into how and why.

In this episode:

 

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16 Nov 2022Ep 97 - The Good Nurse Part I00:57:55

In today's episode, Harini provides a play-by-play of The Good Nurse, Netflix's recent true-crime biopic that details the harrowing story of nurse Amy Loughren who became a confidential informant for the New Jersey Police Department in their efforts to catch serial killer Charles Cullen. Cullen was a nurse who moved discreetly within the healthcare industry for 16 years before being caught for poisoning and murdering patients. As Part I, this episode will cover the film adaptation of this incredible story. Stay tuned for Part II which will shed more light on the events that occurred in real life. 

Sources:

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31 May 2023Ep 117 - Snail Slime and Skincare00:38:14

In today's episode, Megan talks about the slime-tastic world of snail mucin and how, in the past 10 years, it has gained a foothold in the beauty/skincare industry. Is slime mucin simply a gimmicky ingredient advertised to coerce the curious (or desperate) to shell out more money on skincare products? Or does it actually have scientifically-backed qualities that benefit human skin? Megan has the answers. 

Also mentioned...Harini is a Telly Award Winner! Check out her winning videos below: 

Where the Heck do Eels Come From?  (Silver Award 44th Annual Telly Awards)

Are F1 Drivers Athletes? (Bronze Award 44th Annual Telly Awards)

 

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02 Nov 2022Ep 95 - River on Fire: The Environmental Oopsie that Changed America00:45:35

In 1969, a river in the midwest caught on fire for 24 minutes. Despite its minimal damage and zero death-toll, this short-lived fire had a lasting impact on the United States. Its legacy includes the Environmental Protection Agency (EPA), the Clean Water Act, and Earth Day. How did this pitiful fire become a raging beacon in the battle against environmental pollution? Megan explains. 

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04 Aug 2021Ep 36 - The 100 ml Race!01:12:09

The Olympics are happening at the time of this recording, so of course we found you, poison pals, an Olympic poisoning. Yea, you heard that right. Jump in the water with us, because we're diving straight into this episode. Harini takes us back to the 1932 Olympics in Los Angeles, California, where a young Olympic swimmer, Zus Braun, gets mysteriously ill during her qualifying race. She feels a sharp prick on her leg and when she gets out of the water, she sees two American men exit the stadium. What or who is the culprit? Oh, we can't give it all away so fast! Listen in poison pals - on your marks, get set, GO.

 

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Episode Sources:

  • Image 1 Zus Braun, Gold medal Olympic Swimmer from the 1930s (via Wikipedia)

  • https://www.sbnation.com/secret-base/22291303/zus-braun-eleanor-holm-1932-olympic-swimming

  • http://isoh.org/wp-content/uploads/2015/04/90.pdf

  • https://www.olympedia.org/athletes/49375

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07 Sep 2022(Encore) Ep 87 - The Headache From Hell00:52:41

We're bringing you an encore presentation of the story that inspired this podcast (plus bonus commentary!). Harini talks about the Chicago Tylenol Murders (or Tylenol Murders) of 1982 and how this terrorizing event completely changed the pharmaceutical industry's drug-packaging practices. It also influenced stricter Federal anti-tampering legislation. Although copycat attempts of drug tampering and poisoning threatened the nation immediately following the Chicago murders, the case remains open to this day with no true leads. 

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In this episode:

  • McMillions documentary on HBO 
  • Avenue Beat (music) @avenuebeat

Sources:

See omnystudio.com/listener for privacy information.

26 Apr 2023Ep 115 - Golden Geese and Cone Snails00:37:41

In today's episode, Harini regales us with the origin story of the Golden Goose Awards (formerly Golden Fleece Awards) - a designation given to impactful research projects that, from the outset, may not seem potentially beneficial to society, but end up being so. One such project involved an obsession with cone snails and their ability to paralyze fish with a unique peptide cocktail hidden in their lethal stingers. Tune in to find out more! 

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10 Nov 2021Ep 48 - One Rock to Rule Them All01:20:30

We are BACK to our regularly scheduled content of deliciously poisonous, forensic, true crime episodes! Harini brings us back with a bang to discuss the most famous scientist you never heard of, Dr. Clair Patterson. This episode starts out with one story and ends up in an entirely different story.  The only hint as to what the story is about: it's elementary my dear Watson.

 

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27 Jul 2022(Encore ) Ep 81 - Terrifyingly Toxic Glow00:44:27

We're back with another re-record! In this episode, Harini illuminates (see what we did there?) the once deadly fad of Radium-226. This enchanting, glowing isotope became a worldwide obsession and was literally the most fashionable commodity in the 1920s. It was used in food, makeup, clothes, decor, medicine, you name it! Even having a paid occupation in Radium-226 manufacturing was extremely coveted (eg. Radium Girls). Tune in to find out how this naive obsession bred painful, and sometimes deadly, results. 

 

In this episode:

  • 'Radioactive' (film) on Amazon Prime
  • 'The Radium Girls' (film) starring Joey King

 

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Episode Sources: 

  • Radium Girls from the Wired written by Deborah Blum
  • CNN article titled "Girls: the dark times of luminous watches" by Jacopo Prisco
  • NPR article titled May Keane, One of the last ‘Radium Girls’ Died at 107 by Rebecca Hersher
  • How We Realized Putting Radium in Everything Was Not the Answer from the Atlantic by Taylor Orci
  • Mentalfloss
  • Wikipedia  
  • https://www.mskcc.org/news/hot-times-radium-hospital-history-radium-therapy-msk

See omnystudio.com/listener for privacy information.

04 May 2022Ep 70 - The Martha Mitchell Effect01:01:13

Today's episode is about a woman you've probably never heard of, but absolutely should. Her story involves glamour, kidnapping, drugs, a perilous secret, and even the President of the United States. Let us tell you about Martha Mitchell and how her name became synonymous with a term in a psychology book.

In this episode:

  • Gaslit (TV series on Starz) 

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28 Sep 2022Milk of the Poppy: Poisons in Game of Thrones01:03:48

House of the Dragon on HBO Max has been out for over a month now and fans of the original Game of Thrones are having a field-day comparing the two storylines, ourselves included! In this episode, we wanted to talk about notable drugs and poisons that play a large role in the Song of Ice and Fire universe. Moon tea, anyone?

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Episode Sources:

See omnystudio.com/listener for privacy information.

14 Sep 2022*SPECIAL ANNOUNCEMENT*00:04:57

The Deadly Dose is now on Patreon! Through the Deadly Dose Podcast Patreon (aka the DDPP... or should it be D2P2?) we'll be dropping exclusive content from bonus episodes to reaction videos to merchandise. Click the direct link below to see subscription options and what each membership-tier has to offer. OR sit back, relax, hit play, and we'll tell you all about it. 

Patreon

Official Website

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30 Nov 2022Ep 99 - The Good Nurse Part 201:06:30

In today's episode, Harini reviews the new Netflix documentary Capturing the Killer Nurse, a supplement to the streaming platform's recently released The Good Nurse. Both films depict the actions and eventual capture of serial killer Charles Cullen, and how the self-interest of healthcare employers and prioritization of hospital reputations ultimately prolonged his arrest and put patients at risk. Harini provides a play-by-play of how the documentary compares to the dramatized version of this tragic story. 

In today's episode, Harini provides a play-by-play of The Good Nurse, Netflix's recent true-crime biopic that details the harrowing story of nurse Amy Loughren who became a confidential informant for the New Jersey Police Department in their efforts to catch serial killer Charles Cullen. Cullen was a nurse who moved discreetly within the healthcare industry for 16 years before being caught for poisoning and murdering patients. As Part I, this episode will cover the film adaptation of this incredible story. Stay tuned for Part II which will shed more light on the events that occurred in real life. 

Sources:

If you liked this episode please rate, review and subscribe!

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10 Aug 2022(Encore) Ep 83 - MK Ultra Part I, Candy Skies & Kaleidoscope Eyes00:55:28

It’s a Deadly Dose re-release! We’re bringing back Harini’s coverage of MK Ultra and all the questionable, unsanctioned sh*t that occurred under this infamous CIA mind-control program.  LSD and other drug experiments (read: torture?) ran rampant from the 1950s to 1970s in a bid to beat the Communists. Hold onto your bell bottoms and rose-colored glasses because it's going to be a TRIP! 

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In this episode:

  • The Great British Bake Off

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03 Aug 2022(Encore) Ep 82 - That Sandwich is Poison00:54:49

It's a Deadly Dose re-release! With the recent Italian grinder sandwich trending across the internet, we wanted to bring back this incredible story of a serial sandwich poisoner in Germany. We've added bonus commentary reflecting on how far we've come in the last two years. We hope you enjoy! Just like how you'd enjoy a delicious sandwich.

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In this episode:

  • Where the Crawdad's Sing by Delia Owens
  • Arthur from PBS Kids 
  • The Bridge or Bron/Broen 2011 TV Series 
  • Fake or Fortune from BBC One, now streaming on Amazon Prime

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20 Apr 2022Ep 68 - Rhymes with Beth01:03:44

We're cutting to the chase. This story is the real life Breaking Bad. Two professors work together to make meth in their chem lab. But, it's so much more than that...

In this episode:

  • Breaking Bad (TV series) 

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15 Sep 2021Ep 41 - Just Horsing Around!01:03:33

This is the Mythbusters edition of TSIP because we are debunking a hot topic that is trending around the world: Ivermectin! Is it a horse medication? Can you use it for COVID-19? Does it turn you into a horse? Megan gives us all our A's to our Q's. 

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05 Jul 2023Ep 119 - Ozempic: No Longer Hot Right Now01:24:12

In today's episode, Megan provides a step-by-step update on her compounded semaglutide journey. She and Harini also contemplate the quick but quiet death of the Ozempic craze (at least by frenzied-netizen-discourse standards). Why were we all so passionately opiniated about Ozempic for five months, and now can barely get DailyMail to cover it? And what has the FDA had to say since the Ozempic name has become passé? Tune in to find out!

NOTE: Since the recording of this episode, the American Diabetes Association has released new data on a wide-array of novel GLP-1 agonists ("obesity drugs") that truly make semaglutide old news. Read about it here: https://www.theatlantic.com/health/archive/2023/06/ozempic-pills-obesity-drugs-semaglutide/674541/

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02 Mar 2022Ep 61 - Down by the Minamata Bay (Part 2)00:49:04

Megan finishes out her two-part series on the Minamata Bay disaster. How does a massive environmental disaster in Minamata Japan end up manifesting in the same way for THREE generations, halfway across the world in Canada? Your guess is as good as ours. 

In this episode:

https://www.cbc.ca/news2/interactives/children-of-the-poisoned-river-mercury-poisoning-grassy-narrows-first-nation/

Minamata (Film 2020) feat. Johnny Depp 

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08 Dec 2021Ep 51 - Re: Burn Pits (our editor's personal story)00:50:17

Two episodes ago, we talked about burn pits. In that episode, we called on our listeners to email us if they knew anyone that was around or had been exposed to burn pits. We had no idea we were about to get an email so close to home. Today we have Braydon Griffith, our podcast editor, and co-producer, sharing his personal story of how he lost his father to cancer due to exposure to burn pits. Please listen to this episode and share Braydon's story with as many people as you can. Thank you, poison pals.

In this episode:

Kamp Kesem UCSD

Non-Profit Veteran Advocacy Group

VA Burn Pit Registry

Resources to Understand and Track Senate Bill 952- Presumptive Benefits for War Fighters Exposed to Burn Pits and Other Toxins Act

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29 Sep 2021Ep 43 - Fact or Fodder?01:00:17

Step inside this real-life Assassin's Creed episode as Megan takes us all back to the 15th c Italian Renaissance. Wine is sloshing around in your chalice, the bard is singing in the square, and the artist is painting his newest commissioned work by the powerful Borgia family. And all of the above is surrounded by a lifestyle of poisoning one's enemies to reach the top, but are the Borgias really as notorious for poisoning as the world wants us to think?

In this episode:

  • The Borgias (Netflix)
  • Sex Education (S3 on Netflix)
  • A Banquet of Consequences by Elizabeth George (Detective Novel)

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08 Sep 2021Ep 40 - The Mirror Image Disaster01:21:56

An epidemic of neonatal deformities swept across the globe throughout the ‘50s and ‘60s. Virtually healthy mothers were scratching their heads and begging for answers. Was it genetic? No. Environmental? No. It was something else - a miracle drug that promised expecting mothers a cure for every discomfort that could be experienced during their pregnancy. That drug was called Thalidomide and it was one of the biggest disasters in pharmaceutical history.

 

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Episode Sources:

  • Image 1: Children from the thalidomide tragedy (via ABC News)

  • Image 2: The R and S enantiomer structures of thalidomide that produce wildly different responses (via Wikipedia)

  • https://pubmed.ncbi.nlm.nih.gov/21507989/

  • https://www.understandinganimalresearch.org.uk/news/sixty-years-on-the-history-of-the-thalidomide-tragedy

  • https://www.dana-farber.org/newsroom/news-releases/2018/after-60-years--scientists-uncover-how-thalidomide-produced-birth-defects/

  • https://www.theguardian.com/society/2012/sep/01/thalidomide-scandal-timeline

  • https://www.nytimes.com/2020/03/23/health/thalidomide-survivors-usa.html

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14 Sep 2022(Encore) Ep 88 - The Devil's Nightcap00:56:57

We've brought you an encore presentation of "The Devil's Nightcap" with added commentary and an update on a recent discovery in the ongoing investigation into Shastri's death. 

In 1966, the second Prime Minister of India, Lal Bahadur Shastri, died under mysterious circumstances in Tashkent, Uzbekistan a day after signing the Tashkent Agreement (a peace treaty to end the Indo-Pakistan War). Family and followers believed he was poisoned. To this day, the Indian Government keeps Shastri's post-mortem results sealed and confidential to the public. Did he die of natural causes, or is a geopolitical conspiracy afoot?

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Episode Sources:

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02 Feb 2022Ep 57 - The Red Herring01:19:20

This is a story that isn't as straightforward upon first glance. Two loving parents rush their very sick baby to the hospital and one of them goes home, but the other goes to jail. All the clues point to anti-freeze poisoning, time and time again. But, is that all just a red herring...? In today's episode, Harini discusses the Patty Stallings case. 

In this episode:

Unsolved Mysteries Episode 3.28 (Aired May 9, 1991) 

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