
Performance Around The Clock (Dr. Satchin Panda)
Explorez tous les épisodes de Performance Around The Clock
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12 Jun 2024 | Elisabeth Sage Epstein - cholesterol. Performance Around The Clock episode 9. | 00:53:54 | |
In episode 9 of Performance Around the Clock, we are delighted to talk to cardiologist, Dr. Elizabeth Sage Epstein again. Dr. Epstein and Dr. Panda discuss the role of cholesterol in cardiovascular disease risk. The conversation covers topics such as the absorption of fat and cholesterol in the body, the impact of LDL particles on plaque formation in coronary arteries, and the use of advanced cardiology techniques, such as NMR LipoProfile and calcium scoring, to assess cardiovascular health. Dr. Epstein emphasizes the importance of understanding cholesterol levels and how they contribute to the risk of cardiovascular disease, and also highlights the potential for lifestyle changes to reverse plaque development. Guest: Dr. Elizabeth Sage Epstein, Scripps Health, Integrative Cardiology Fellow X (formerly Twitter): @lizziesageMD https://twitter.com/lizziesageMD Author: A Beautiful Heart Cookbook: Heart-Healthy Recipes for a Long, Happy Life https://www.amazon.com/Beautiful-Heart-Cookbook-Heart-healthy-Recipes/dp/1982234164 Host: Dr. Satchin Panda X (formerly Twitter): @SatchinPanda https://twitter.com/satchinpanda Instagram: https://www.instagram.com/satchin.panda/ Links: Donations: https://panda.salk.edu/giving/ Research: https://www.salk.edu/scientist/satchidananda-panda/ More science: https://mycircadianclock.org/ | |||
19 Nov 2024 | Phyllis Zee - sleep, melatonin and circadian health clinics. Performance Around The Clock episode 25. | 00:39:20 | |
We continue our series from the Society for Research on Biology Rhythms (SRBR) biennial meeting in San Juan, Puerto Rico. In episode 25 of the Performance Around The Clock podcast, we have the pleasure of speaking with Dr. Phyllis Zee, one of the world’s experts on sleep. Dr. Zee is a Director of the Center of Circadian and Sleep Medicine at Feinberg School of Medicine at Northwestern University. She is also the Chief of Sleep Medicine in the Department of Neurology and Benjamin and Virginia T. Boshes Professor of Neurology. In this episode, she talks about sleep disorders, using melanopsin as a chronobiotic, the interesting connection between melatonin and glucose metabolism and the establishment of circadian health clinics. Thanks for listening. Guest: Dr. Phyllis Zee Director, Center for Circadian and Sleep Medicine Feinberg School of Medicine at Northwestern University Chief of Sleep Medicine in the Department of Neurology Benjamin and Virginia T. Boshes Professor of Neurology X (Twitter): @PhyllisZee https://x.com/phylliszee Profile: https://www.feinberg.northwestern.edu/faculty-profiles/az/profile.html?xid=13785 International Association of Circadian Health Clinics https://circadianhealthclinics.com/ Host: Dr. Satchin Panda X (Twitter): @SatchinPanda https://x.com/SatchinPanda Instagram: @satchin.panda https://www.instagram.com/satchin.panda/ Links: Donations: https://panda.salk.edu/giving/ Research: https://www.salk.edu/scientist/satchidananda-panda/ More science: https://mycircadianclock.org/ | |||
12 Jun 2024 | Amita Seghal - sleep and timeless gene. Performance Around The Clock episode 13. | 01:04:54 | |
Dr. Amita Sehgal, a Howard Hughes investigator studying circadian rhythms and sleep, joins episode 13 of the podcast this week to talk about her career including the discovery of the Drosophila TIM gene and her pivotal role in the development of Drosophila as a model for the study of sleep. Enjoy! Guest: Dr. Amita Sehgal John Herr Musser Professor in the neuroscience department at the Perelman School of Medicine at the University of Pennsylvania https://www.med.upenn.edu/sehgallab/ X (formerly Twitter): @amitaseh https://twitter.com/amitaseh Host: Dr. Satchin Panda X (formerly Twitter): @SatchinPanda https://twitter.com/SatchinPanda Instagram: @satchin.panda https://www.instagram.com/satchin.panda/ Links: Donations: https://panda.salk.edu/giving/ Research: https://www.salk.edu/scientist/satchidananda-panda/ More science: https://mycircadianclock.org/ | |||
11 Feb 2025 | Steven Austad - longevity and aging. Performance Around the Clock episode 29. | 01:38:36 | |
Episode 29 of the Performance Around the Clock Podcast is our second episode from the 2024 Gerontology Society of America (GSA) Annual Scientific Meeting in Seattle. We are privileged to host Dr. Steven Austad who is a leading expert in aging biology. Dr. Austad is a Distinguished Professor and Chair of Biology at the University of Alabama at Birmingham, Director of UAB's Nathan Shock Center of Excellence in the Basic Biology of Aging and Senior Scientific Director of the American Federation for Aging Research (AFAR). His varied career from large cat training, longevity field work with opposums, calculating the age of greenland sharks, to work with numerous other species gives Dr. Austad a unique view on longevity and aging. He developed the Longevity Quotient (LQ) which is simplified measure that enables normalized comparisons of various species' longevity. Learn all about his work on longevity and aging in this episode. If you like this episode, please like or follow/subscribe. Thank you for listening. In addition to authoring over 200 scientific articles and more than 150 newspaper columns on science. Dr. Austad has been a recipient of numerous awards such as: Fifth Nathan A. Shock Award Robert W. Kleemeier award Purdue University Outstanding Alumnus Award Irving S. Wright Award of Distinction Fondation IPSEN Longevity Prize Caroline P. and Charles W. Ireland Prize for Scholarly Distinction. He is also a fellow of the Gerontological Society of America (GSA) and the American Association for the Advancement of Science (AAAS). In 2021, he was appointed Protective Life Endowed Chair of Health Aging Research at the University of Alabama at Birmingham. Guest: Dr. Steven Austad's X (formerly Twitter): @StevenAustad UAB Faculty Page https://www.uab.edu/cas/biology/people/faculty/steven-n-austad Books: “Why We Age” https://www.amazon.com/Why-We-Age-Science-Discovering/dp/0471148032/ "Methuselah's Zoo." https://www.amazon.com/Methuselahs-Zoo-Nature-Living-Healthier/dp/B0CL5D1SY7/ Host: Dr. Satchin Panda X (Twitter): @SatchinPanda https://x.com/SatchinPanda Instagram: @satchin.panda https://www.instagram.com/satchin.panda/ Links: Donations:https://panda.salk.edu/giving/ Research:https://www.salk.edu/scientist/satchidananda-panda/ More science:https://mycircadianclock.org/ | |||
21 Aug 2024 | Christoph Scheiermann - circadian immune system. Performance Around The Clock episode 20. | 00:33:42 | |
Performance Around the Clock episode 20 comes from the 2024 Society for Research on Biology Rhythms (SRBR) biennial meeting in San Juan, Puerto Rico. We have the pleasure to talk with Dr. Christoph Scheiermann who studies the role of circadian rhythms in immune response and how this impacts health and disease. In particular, he’s known for his research on the recruitment and localization of leukocytes which is under circadian control. This process plays a crucial role in immune response which can be leveraged to improve cancer immunotherapy and vaccination efficacy. Learn more about his impactful research in this episode. Thanks for listening. Guest: Dr. Christoph Scheiermann Full Professor Department of Pathology and Immunology Centre Medical Universitaire (CMU) X (formerly Twitter): @ScheiermannLab https://twitter.com/ScheiermannLab Lab webpage: http://scheiermannlab.de/ Host: Dr. Satchin Panda @SatchinPanda https://x.com/SatchinPanda Instagram: @satchin.panda https://www.instagram.com/satchin.panda/ | |||
12 Jun 2024 | Amber Mueller - life as science editor and exercise metabolism. Performance Around The Clock episode 15. | 00:53:21 | |
This week’s episode of the Performance Around the Clock podcast (episode 15) comes from the Cell Symposium on Exercise Metabolism in Lisbon, Portugal. Dr. Amber Mueller, scientific editor at Cell Metabolism and co-organizer of the symposium talks to us about life as a scientific editor and about the field of exercise metabolism. Enjoy! Guest: Dr. Amber Mueller Scientific Editor at Cell Metabolism X (formerly Twitter): @AmberMuellerPhD https://twitter.com/AmberMuellerPhD Host: Dr. Satchin Panda X (formerly Twitter): @SatchinPanda https://twitter.com/SatchinPanda Instagram: @satchin.panda https://www.instagram.com/satchin.panda/ Links: Donations: https://panda.salk.edu/giving/ Research: hhttps://www.salk.edu/scientist/satchidananda-panda/ More science: https://mycircadianclock.org/ | |||
12 Jun 2024 | Tinh-Hai Collet - diabetes and time-restricted eating. Performance Around The Clock episode 4. | 01:17:10 | |
In episode 4 of the podcast, Dr. Tinh-Hai Collet, a physician and principal investigator at Geneva University Hospital, discusses with Dr. Satchin Panda his experience combining lifestyle interventions like meal timing and circadian rhythms with medicine to manage chronic conditions in patients. We discuss Dr. Collet's research on time-restricted eating, including a 6-month randomized controlled trial in Switzerland. We also discuss implementing lifestyle changes like intermittent fasting under medical supervision, potential side effects, impacts on conditions like diabetes and hypertension, and the importance of spreading circadian health knowledge among more physicians. Overall, this conversation highlights the potential for optimizing meal timing and circadian rhythms, alongside medication when needed, to improve health outcomes. Guest: Dr. Tinh-Hai Collet Diabetes Center of the Geneva University Hospital (HUG) https://www.unige.ch/medecine/diabetescentre/membres/dr-tinh-hai-collet Host: Dr. Satchin Panda X (formerly Twitter): @SatchinPanda https://twitter.com/SatchinPanda https://www.instagram.com/satchin.panda/ Links: Donations: https://panda.salk.edu/giving/ Research: https://www.salk.edu/scientist/satchidananda-panda/ More science: https://mycircadianclock.org/ | |||
12 Jun 2024 | Horacio de la Iglesia - high school and ancestral start times. Performance Around The Clock episode 6. | 01:35:03 | |
In episode 6 of Performance Around the Clock, host Professor Satchin Panda interviews Dr. Horacio de la Iglesia, a sleep and circadian expert from the University of Washington. We discuss how circadian rhythms affect nearly every aspect of human physiology and behavior, from hormone levels to sleep-wake cycles. Dr. De la Iglesia shares insights from his research on ancestral populations like the Toba who live without electricity, as well as modern teenagers and the impact of light exposure, sleep deprivation, and delayed school start times. We discuss the need to educate the public and medical community about circadian health. The episode highlights how circadian biology can inform public policy and simple lifestyle changes we can make, like increasing natural daylight exposure, to improve health. Guest: Dr. Horacio de la Iglesia Professor, University of Washington X (formerly Twitter): @horacioIglesia Host: Dr. Satchin Panda X (formerly Twitter): @SatchinPanda https://twitter.com/SatchinPanda https://www.instagram.com/satchin.panda/ Links: Donations: https://panda.salk.edu/giving/ Research: https://www.salk.edu/scientist/satchidananda-panda/ More science: https://mycircadianclock.org/ | |||
07 Sep 2024 | Achim Kramer - BodyTime and circadian medicine. Performance Around The Clock episode 21. | 01:09:19 | |
Episode 21 of the Performance Around the Clock podcast comes from the 2024 Society for Research on Biology Rhythms (SRBR) biennial meeting in San Juan, Puerto Rico. This week’s guest is Dr. Achim Kramer who developed an assay (BodyTime) to determine internal circadian time. He talks about the development of the assay and how it can be used in circadian medicine. Dr. Kramer is Head of Chronobiology at Charité – Universitätsmedizin Berlin, the largest research hospital in Europe. Thank you for listening. Guest: Dr. Achim Kramer Head of Chronobiology at Charité – Universitätsmedizin Berlin Lab website: https://www.achim-kramer-lab.de/ Body clock test: BodyTime High-accuracy determination of internal circadian time from a single blood sample https://pubmed.ncbi.nlm.nih.gov/29953415/ Host: Dr. Satchin Panda @SatchinPanda https://x.com/SatchinPanda Instagram: @satchin.panda https://www.instagram.com/satchin.panda/ Links: Donations: https://panda.salk.edu/giving/ Research: https://www.salk.edu/scientist/satchidananda-panda/ More science: https://mycircadianclock.org/ | |||
28 Nov 2024 | Jamie Justice - gerontology, biomarkers and XPRIZE Healthspan. Performance Around The Clock episode 26. | 01:23:22 | |
Episode 26 of the Performance Around The Clock podcast comes from the GSA (Gerontological Society of America) meeting in Seattle. We are delighted to host, Dr. Jamie Justice, who is the Executive Vice President of the Health Domain at XPRIZE Foundation and adjunct professor in Gerontology and Geriatric Medicine at the Wake Forest University School of Medicine. We talk about her career in gerontology, expertise with biomarkers and XPRIZE Healthspan. Join us for an enlightening conversation about aging and learn about the big XPRIZE Healthspan initiative. Thank you for listening. Guest: Dr. Jamie Justice Executive Vice President of the Health Domain at XPRIZE Foundation Adjunct Professor in Internal Medicine Section on Gerontology and Geriatric Medicine, and Sticht Center on Healthy Aging and Alzheimer’s Prevention at Wake Forest University School of Medicine (WFUSM) - Jarrahi Research Scholars Fund in Geroscience Innovation - 2022 Vincent Cristofalo Rising Star in Aging Research - 2022 NIA Nathan W Shock Awardee XPRIXE profile: https://www.xprize.org/about/people/jamie-justice-ph-d XPRIZE Healthspan: https://www.xprize.org/prizes/healthspan TAME study: https://pubmed.ncbi.nlm.nih.gov/30151729/ Host: Dr. Satchin Panda X (Twitter): @SatchinPanda https://x.com/SatchinPanda Instagram: @satchin.panda https://www.instagram.com/satchin.panda/ Links: Donations: https://panda.salk.edu/giving/ Research: https://www.salk.edu/scientist/satchidananda-panda/ More science: https://mycircadianclock.org/
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12 Jun 2024 | Juleen Zierath - exercise and metabolic disease. Performance Around The Clock episode 2. | 00:56:08 | |
Episode 2 of Performance Around the Clock features Dr. Juleen Zierath who is a Professor of Physiology at the Karolinska Institutet and the University of Copenhagen. We discuss with Dr. Zierath about using exercise as medicine for metabolic diseases like obesity, diabetes, and cardiovascular disease. This includes how exercise affects multiple organs and systems in the body, improving insulin sensitivity, bone density, cognition, and more. Dr. Zierath shares research on optimal timing of exercise for blood sugar control, showing benefits from afternoon exercise over morning for diabetics. We also cover personalized exercise prescriptions, prenatal and preconception exercise impacts, and the importance of societal support and public policy in enabling exercise. The episode provides some scientific evidence and advice for using exercise to boost health. Guest: Dr. Juleen Zierath Professor of Physiology at Karolinska Institutet and the University of Copenhagen. X (formerly Twitter): @JuleenRZierath Host: Dr. Satchin Panda X (formerly Twitter): @SatchinPanda https://twitter.com/SatchinPanda Instagram: https://www.instagram.com/satchin.panda/ Links: Donations: https://panda.salk.edu/giving/ Research: https://www.salk.edu/scientist/satchidananda-panda/ More science: https://mycircadianclock.org/ | |||
12 Jun 2024 | Michael Lam - sleep and the immune system. Performance Around The Clock episode 7. | 01:36:11 | |
In episode 7 of the Performance Around the Clock podcast, Dr. Panda talks with Dr. Michael Lam who is a pulmonologist and assistant professor at the UCSD in the Department of Medicine and in the Division of Pulmonary, Critical Care, and Sleep Medicine. They explore the science of the immune system and link with circadian rhythms, delving into the impact of sleep, light, and even meal timing on the body's immune system. They also discuss challenges faced in the ICU and strategies for improving recovery. Guest: Dr. Michael T Lam, (MD/PhD) Assistant Professor Division of Pulmonary, Critical Care, and Sleep Medicine Department of Medicine University of California, San Diego https://profiles.ucsd.edu/michael.lam Host: Dr. Satchin Panda X (formerly Twitter): @SatchinPanda https://twitter.com/SatchinPanda https://www.instagram.com/satchin.panda/ Links: Donations: https://panda.salk.edu/giving/ Research: https://www.salk.edu/scientist/satchidananda-panda/ More science: https://mycircadianclock.org/ | |||
12 Jun 2024 | Laura van Rosmalen - seasonal rhythms, activity & energy balance, REDS. Performance Around The Clock episode 14. | 01:05:09 | |
In episode 14 of the Performance Around the Clock podcast, Dr. Laura van Rosmalen, a WuTsai scholar and postdoctoral researcher at the Salk Institute joins us to talk about her work with voles and seasonal rhythms, diurnality, nocturnality and energy balance, and a surprising connection with RED-S (Relative Energy Deficiency in Sport). Enjoy! Guest: Dr. Laura van Rosmalen WuTsai scholar Salk Institute for Biological Studies X (formerly Twitter): @RosmalenLaura https://twitter.com/RosmalenLaura Host: Dr. Satchin Panda X (formerly Twitter): @SatchinPanda https://twitter.com/SatchinPanda Instagram: @satchin.panda https://www.instagram.com/satchin.panda/ Links: Donations: https://panda.salk.edu/giving/ Research: https://www.salk.edu/scientist/satchidananda-panda/ More science: https://mycircadianclock.org/ | |||
22 Oct 2024 | Annie Curtis - circadian immunology. Performance Around The Clock episode 24. | 00:47:48 | |
Welcome to episode 24 of the Performance Around The Clock podcast. We resume our series from the Society for Research on Biology Rhythms (SRBR) biennial meeting in San Juan, Puerto Rico. In this episode, we are joined by Dr. Annie Curtis, a professor at the Royal College of Surgeons in Ireland (RCSI), who studies the intersection between circadian rhythms and the immune system. We talk about how the timing of infection affects the immune response and the implications for vaccinations. In addition, we hear about the intriguing role of mitochondria in this immune response. Thanks for listening. Guest: Dr. Annie Curtis Associate Professor Royal College of Surgeons in Ireland (RCSI) School of Pharmacy and Biomolecular Sciences Principal Investigator of the Tissue Engineering Research Group (TERG) Executive Committee for the Irish Society for Immunology between 2016-2020 L’Oreal Women in Science Fellowship in 2017 SFI Career Development Award in 2017 Irish Research Council Laureate Award in 2018 President of the Irish Society for Immunology 2020-2022 SFI Frontiers Award in 2021 Host: Dr. Satchin Panda @SatchinPanda https://x.com/SatchinPanda Instagram: @satchin.panda https://www.instagram.com/satchin.panda/ Links: Donations: https://panda.salk.edu/giving/ Research: https://www.salk.edu/scientist/satchidananda-panda/ More science: https://mycircadianclock.org/ | |||
12 Jun 2024 | Hiroki Ueda - Circadian Rhythms. Performance Around The Clock episode 1. | 01:39:22 | |
In this episode of Performance Around the Clock, host professor Satchin Panda interviews Dr. Hiroki Ueda, a circadian rhythm researcher at the University of Tokyo medical school and the RIKEN research institute in Japan. We discuss Dr. Ueda's pioneering work using genomics and imaging techniques to study how genes that regulate circadian rhythms turn on and off at different times of day in various tissues and organs. This research helps explain how disrupted circadian rhythms negatively impact human health and performance. Dr. Ueda also describes his development of novel genetic tools and microscopic imaging methods to analyze sleep/wake cycles and diseases in animal models. He emphasizes the importance of sleep for optimal brain function and shares new approaches his team is taking to make sleep measurements more practical and scalable for clinical use. Overall, the episode highlights Dr. Ueda's groundbreaking research expanding our understanding of circadian biology and sleep to improve human health. Guest: Dr. Hiroki Ueda Graduate School of Medicine, University of Tokyo Team Leader, Riken BDR Twitter/X: @hiroking1975 Host: Dr. Satchin Panda X (formerly Twitter): @SatchinPanda https://twitter.com/SatchinPanda Instagram: https://www.instagram.com/satchin.panda/ Links: Donations: https://panda.salk.edu/giving/ Research: https://www.salk.edu/scientist/satchidananda-panda/ More science: https://mycircadianclock.org/ | |||
03 Jan 2025 | Till Roenneberg - chronotypes and social jetlag. Performance Around The Clock episode 27. | 00:48:16 | |
Happy 2025! Episode 27 of the Performance Around The Clock podcast is our last from the Society for Research on Biological Rhythms (SRBR) meeting in San Juan, Puerto Rico. We are excited to have Dr. Till Roenneberg on the podcast. Dr. Roenneberg is emeritus professor of chronobiology at the Institute of Medical Psychology at Ludwig-Maximilian University (LMU) in Munich, Germany. He has dedicated most of his career to investigating the effects of light on circadian clocks, sleep, and health and is known for his seminal work with chronotypes and social jetlag. Hear all about his work on chronotypes and social jetlag in this episode. Thank you for listening. If you enjoy this episode or podcast, please like, subscribe or comment. Thank you. Guest: Dr. Till Roenneberg Prizes and Awards: 1987 Harvard-Hoops Prize for Excellence in Teaching 1993 Honma Prize "Outstanding contributions to the field of chronobiology” 1998 "Aschoff's Ruler" Research Prize 2004 Silver Medal (University of Munich) 2011 Professional Lighting Design Recognition Award for Research and Education 2012-2015 President European Biological Rhythms Society 2013 Science Book Award of the British Medical Association Board 2016 Galileo Award Italian Science Book Prize 2018 Innovation in Academia Award (University of Kent) 2019 Ambassador of Sleep (German Sleep Foundation) 2024 Daylight Award for Daylight Research Profile: https://www.mcn.uni-muenchen.de/members/regular/roenneberg/index.html Host: Dr. Satchin Panda X (Twitter): @SatchinPanda https://x.com/SatchinPanda Instagram: @satchin.panda https://www.instagram.com/satchin.panda/ Links: Donations: https://panda.salk.edu/giving/ Research: https://www.salk.edu/scientist/satchidananda-panda/ More science:https://mycircadianclock.org/ | |||
06 Aug 2024 | Joseph Takahashi - discovery of Clock gene, circadian alignment, CR and longevity. Performance Around The Clock episode 19. | 01:11:45 | |
Episode 19 of the Performance Around the Clock podcast comes from the 2024 Society for Research on Biological Rhythms (SRBR) biennial meeting in San Juan, Puerto Rico. We have the honor to talk with one of the pillars of the circadian field - Dr. Joseph Takahashi. Dr. Takahashi pioneered the use of forward genetics and positional cloning in mouse as a tool to discover genes that underlie neurobiology and behavior. His discovery of clock genes led to a description of a conserved circadian clock mechanism in animals. In this podcast, we hear about how his lab discovered and cloned the mouse circadianClock gene. In addition, we find out how circadian alignment of feeding, daily fasting and caloric restriction can combine to increase longevity. Dr. Takahashi has authored more than 300+ scientific publications and the recipient of many awards and distinctions including: The Honma Prize in Biological Rhythms Research NSF Presidential Young Investigator Award Searle Scholars Award Bristol-Myers Squibb Unrestricted Grant in Neuroscience, and the C. U. Ariens Kappers Medal. W. Alden Spencer Award in Neuroscience from Columbia University Fellow of the American Academy of Arts and Sciences Member of the National Academy of Sciences Member of the National Academy of Medicine Gruber Neuroscience Prize at the Society for Neuroscience Guest: Dr. Joseph Takahashi Chair of the Department of Neuroscience at UT Southwestern Medical Center Loyd B. Sands Distinguished Chair in Neuroscience X (formerly Twitter): @CircadianClocks https://twitter.com/circadianclocks UT Southwestern profile: https://profiles.utsouthwestern.edu/profile/105885/joseph-takahashi.html Lab webpage: https://labs.utsouthwestern.edu/takahashi-lab Host: Dr. Satchin Panda @SatchinPanda https://x.com/SatchinPanda Instagram: @satchin.panda https://www.instagram.com/satchin.panda/ Links: Donations: https://panda.salk.edu/giving/ Research: https://www.salk.edu/scientist/satchidananda-panda/ More science: https://mycircadianclock.org/ | |||
25 Mar 2025 | Nathan LaBrasseur - senescence and aging. Performance Around the Clock episode 31. | 01:11:38 | |
Coming from the 2024 Gerontology Society of America (GSA) Annual Scientific Meeting in Seattle, we are excited to welcome Dr. Nathan LaBrasseur for the 31st episode of the Performance Around the Clock podcast. Dr. LaBrasseur is the director of the Robert and Arlene Kogod Center on Aging at the Mayo Clinic and an expert on senescence and aging. He's an author of the book "Mayo Clinic on Healthy Aging: An Easy and Comprehensive Guide to Keeping Your Body Young, Your Mind Sharp and Your Spirit Fulfilled" an updated guide on healthy aging. In this episode, learn about the latest in aging and senescence particularly therapeutics for senescent cells - senotherapeutics. Senotherapeutics can be broken down into senolytics which selectively kill senescent cells and senomorphics which suppress senescence-associated secretory phenotype (SASP) to reduce the negative effects of senescence. Thank you for watching. If you like this episode, please like, comment or subscribe. Guest: Dr. Nathan LaBrasseur Director of the Robert and Arlene Kogod Center on Aging @MayoClinic X (Twitter): @NKLeBRASSEUR https://x.com/nklebrasseur Profile: https://www.mayo.edu/research/faculty/lebrasseur-nathan-k-ph-d-m-s/bio-00055041 Mayo Clinic on Healthy Aging: An Easy and Comprehensive Guide to Keeping Your Body Young, Your Mind Sharp and Your Spirit Fulfilled https://www.amazon.com/Mayo-Clinic-Healthy-Aging-Comprehensive/dp/B0BQYKS8ND Host: Dr. Satchin PandaX (Twitter): @SatchinPanda https://x.com/SatchinPanda Instagram: @satchin.panda https://www.instagram.com/satchin.panda/ Links: Donations: https://panda.salk.edu/giving/ Research: https://www.salk.edu/scientist/satchidananda-panda/ More science: https://mycircadianclock.org/ | |||
12 Jun 2024 | Greg Lemke - a distinguished scientific career. Performance Around The Clock episode 10. | 01:41:02 | |
In this special, 10th episode of the Performance Around the Clock podcast, we have the honor of speaking with Professor Greg Lemke of the Salk Institute. We discuss his distinguished scientific career from the early beginnings to the discovery of TAM receptor tyrosine kinases. Enjoy. Guest: Dr. Greg Lemke Françoise Gilot-Salk Chair and professor in the Molecular Neurobiology Laboratory Salk Institute for Biological Studies Laboratory: https://www.lemkelab.org/ Salk page: https://www.salk.edu/scientist/greg-lemke/ Host: Dr. Satchin Panda X (formerly Twitter): @SatchinPanda https://twitter.com/SatchinPanda Instagram: https://www.instagram.com/satchin.panda/ Links: Donations: https://panda.salk.edu/giving/ Research: https://www.salk.edu/scientist/satchidananda-panda/ More science: https://mycircadianclock.org/ | |||
17 Jun 2024 | Mark Febbraio - exercise, inflammation and disease. Performance Around The Clock episode 16. | 00:36:29 | |
Episode 16 of the Performance Around the Clock podcast comes from the Cell Symposium on Exercise Metabolism in Lisbon, Portugal and features Dr. Mark Febbraio who is the head of Cellular and Molecular Metabolism Laboratory at Monash Institute of Pharmaceutical Sciences. His research focuses on understanding mechanisms associated with exercise, obesity, type 2 diabetes and cancer with an aim towards developing novel drugs to treat lifestyle related diseases. In this episode, we hear about how he transitioned from a triathlete into a researcher in exercise science. We also learn about the link between exercise and inflammation and leveraging this knowledge to treat disease. Enjoy! Guest: Dr. Mark Febbraio Professor, Drug Discovery Biology Cellular and Molecular Metabolism Laboratory Monash Institute of Pharmaceutical Sciences X (formerly Twitter): @FebbraioMark https://twitter.com/FebbraioMark Host: Dr. Satchin Panda X (formerly Twitter): @SatchinPanda https://twitter.com/SatchinPanda Instagram: @satchin.panda https://www.instagram.com/satchin.panda/ Links: Donations: https://panda.salk.edu/giving/ Research: https://www.salk.edu/scientist/satchidananda-panda/ More science: https://mycircadianclock.org/ | |||
12 Jun 2024 | Kazuo Tsubota - eye health. Performance Around The Clock episode 5. | 00:56:51 | |
In episode 5 of the PATC podcast, ophthalmology expert Dr. Kajuha Shubota discusses key research on how light affects vision and overall health with host Dr. Satchin Panda. He explains how lack of time outdoors and violet light exposure is increasing myopia rates in children, and eyeglasses may exacerbate the issue. He shares how dry eye is linked to stress and lifestyle factors. For presbyopia, he discusses potential drug and lens replacement solutions to improve near vision. Throughout, Dr. Shubota emphasizes how the eye offers valuable insights into aging and diseases like Alzheimer’s, as improving ocular blood flow with light may boost brain function. He remains optimistic that innovations in glasses design and lighting can profoundly improve vision and wellbeing across all life stages. Guest: Dr. Kazuo Tsubota Professor, Department of Ophthalmology, Graduate School of Medicine, Keio University Profile: http://tsubota.ne.jp/en/profile/profile.html Lab page: https://tsubota-lab.com/en/ Host: X (formerly Twitter): @SatchinPanda https://twitter.com/SatchinPanda https://www.instagram.com/satchin.panda/ Links: Donations: https://panda.salk.edu/giving/ Research: https://www.salk.edu/scientist/satchidananda-panda/ More science: https://mycircadianclock.org/ | |||
24 Sep 2024 | Charlotte Förster - perseverance in science and lunar rhythms. Performance Around The Clock episode 22. | 01:09:43 | |
Episode 22 of the Performance Around the Clock podcast is another episode from the 2024 Society for Research on Biology Rhythms (SRBR) biennial meeting in San Juan, Puerto Rico. We are honored to host this week’s guest, Dr. Charlotte Förster, who epitomizes perseverance in her long scientific career studying circadian rhythms We’ll talk about her work to understand the circadian clock at the molecular and neuronal level, how the clock synchronizes with the day/night cycles and how the clock controls behavior. You’ll also hear about her fascinating research on the synchronization of menstrual cycles with lunar cycles and its implications. Dr. Förster is a professor in Neurobiology and Genetics at the University of Würzburg. Thank you for listening. Guest: Dr. Charlotte Forster Chronobiology Professor, Neurobiology and Genetics, University of Würzburg Lab website: https://www.biozentrum.uni-wuerzburg.de/en/neurogenetics/research/wg-foerster/charlotte-foerster/ Host: Dr. Satchin Panda @SatchinPanda https://x.com/SatchinPanda Instagram: @satchin.panda https://www.instagram.com/satchin.panda/ Links: Donations: https://panda.salk.edu/giving/ Research: https://www.salk.edu/scientist/satchidananda-panda/ More science: https://mycircadianclock.org/ | |||
12 Jun 2024 | John Hogenesch - circadian medicine. Performance Around The Clock episode 11. | 01:06:10 | |
In episode 11 of the Performance Around the Clock podcast, we have the privilege of speaking with Professor John Hogenesch - a neuroscientist/genome biologist/chronobiologist at UC Department of Pediatrics at the Cincinnati Children’s Hospital Medical Center. Dr. Hogenesch talks about applying the “principles of circadian biology to hospital medicine”. Enjoy! Guest: Dr. John Hogenesch Professor, UC Department of Pediatrics Cincinnati Children’s Hospital Medical Center https://www.cincinnatichildrens.org/bio/h/john-hogenesch X (formerly Twitter): @jbhclock https://twitter.com/jbhclock Host: Dr. Satchin Panda X (formerly Twitter): @SatchinPanda https://twitter.com/SatchinPanda Instagram: @satchin.panda https://www.instagram.com/satchin.panda/ Links: Donations: https://panda.salk.edu/giving/ Research: https://www.salk.edu/scientist/satchidananda-panda/ More science: https://mycircadianclock.org/ | |||
01 Mar 2025 | Courtney Peterson - intermittent fasting and TRE. Performance Around the Clock episode 30. | 00:52:32 | |
We continue our series from the 2024 Gerontology Society of America (GSA) Annual Scientific Meeting in Seattle. Episode 30 of the Performance Around the Clock Podcast, features Dr. Courtney Peterson, a leading researcher in the field of intermittent fasting and time-restricted eating (TRE). Dr. Peterson is an Associate Professor at the University of Alabama at Birmingham where she was notably the first to test early time-restricted eating (eTRE) in humans. Dr. Peterson is the principal investigator of numerous clinical trials on TRE, including the largest randomized controlled trial of intermittent fasting in individuals with type 2 diabetes. Her research combines chronobiology, nutrition, and metabolism and aims to develop dietary interventions to combat cardiometabolic diseases. Learn all about her research in this episode. If you like this episode, please like, comment or subscribe. Thank you for listening.
Guest: Dr. Courtney Peterson Associate Professor University of Alabama Birmingham X (Twitter): @CourtneyP_PhD Profile: https://scholars.uab.edu/3393-courtney-peterson Early Time-Restricted Feeding Improves Insulin Sensitivity, Blood Pressure, and Oxidative Stress Even without Weight Loss in Men with Prediabetes https://pubmed.ncbi.nlm.nih.gov/29754952/ Host: Dr. Satchin Panda X (Twitter): @SatchinPanda https://x.com/SatchinPanda Instagram: @satchin.panda https://www.instagram.com/satchin.panda/ Links: Donations: https://panda.salk.edu/giving/ Research: https://www.salk.edu/scientist/satchidananda-panda/ More science: https://mycircadianclock.org/ | |||
16 Jul 2024 | Bret Goodpaster - muscles and exercise. Performance Around The Clock episode 18. | 00:37:05 | |
Episode 18, the final episode from the Cell Symposia meeting on Exercise Metabolism in Lisbon, features Dr. Bret Goodpaster. As the Scientific Director at AdventHealth's Translational Research Institute, Dr. Goodpaster is a leading expert in exercise physiology and metabolism. In this episode, he shares his insights on exercise, muscle, aging, and the athlete’s paradox. We also delve into two major scientific projects - HealthABC (Health, Aging Body and Composition) and MoTrPAC (Molecular Transducers of Physical Activity Consortium). HealthABC explores risk factors for functional decline in older adults, including muscle aging. MoTrPAC is a large consortium created to understand the molecular mechanisms of physical activity on health benefits. We hope you will find this episode intellectually stimulating. Thank you for listening. Guest:Dr. Bret Goodpaster Scientific Director at Advent Health’s Translational Research Institute https://www.adventhealthresearchinstitute.com/team/bret-goodpaster Host:Dr. Satchin Panda X (formerly Twitter): @SatchinPanda https://x.com/SatchinPanda Instagram: @satchin.panda https://www.instagram.com/satchin.panda/ Links: Donations: https://panda.salk.edu/giving/ Research: https://www.salk.edu/scientist/satchidananda-panda/ More science: https://mycircadianclock.org/ | |||
12 Jun 2024 | Elizabeth Sage Epstein - cardiac health. Performance Around The Clock episode 8. | 01:08:34 | |
In episode 8 of the Performance Around the Clock podcast, Dr. Satchin Panda has an enlightening conversation with Dr. Elizabeth Sage Epstein, a cardiologist and author. They discuss the importance of the heart and impact on overall health, preventive measures for chronic diseases, the cardiovascular system and the importance of cardiac health in young, active individuals. Guest: Dr. Elizabeth Sage Epstein, Scripps Health, Integrative Cardiology Fellow X (formerly Twitter): @lizziesageMD https://twitter.com/lizziesageMD Author: A Beautiful Heart Cookbook: Heart-Healthy Recipes for a Long, Happy Life https://www.amazon.com/Beautiful-Heart-Cookbook-Heart-healthy-Recipes/dp/1982234164 Host: Dr. Satchin Panda X (formerly Twitter): @SatchinPanda https://twitter.com/SatchinPanda Instagram: https://www.instagram.com/satchin.panda/ Links: Donations: https://panda.salk.edu/giving/ Research: https://www.salk.edu/scientist/satchidananda-panda/ More science: https://mycircadianclock.org/ | |||
12 Jun 2024 | Michael McCarthy - psychiatry and circadian rhythms. Performance Around The Clock episode 12. | 01:20:15 | |
In this episode of the Performance Around the Clock podcast, we welcome Dr. Michael McCarthy, a biological psychiatrist at UCSD and the Veterans Medical Research Foundation. We talk about the latest in psychiatry and how circadian rhythms may be involved. Enjoy. Guest: Dr. Michael McCarthy Profiles: UCSD: https://profiles.ucsd.edu/michael.mccarthy VA: https://www.vmrf.org/copy-of-pi-chitra-mandyam-1 Host: Dr. Satchin Panda X (formerly Twitter): @SatchinPanda https://twitter.com/SatchinPanda Instagram: @satchin.panda https://www.instagram.com/satchin.panda/ Links: Donations: https://panda.salk.edu/giving/ Research: https://www.salk.edu/scientist/satchidananda-panda/ More science: https://mycircadianclock.org/ | |||
01 Oct 2024 | Emily Manoogian - Time-Restricted Eating (TRE). Performance Around The Clock episode 23. | 01:37:49 | |
Welcome to the Performance Around the Clock podcast. In episode 23, we are joined by Dr. Emily Manoogian, one of the foremost experts on Time-Restricted Eating (TRE), to discuss her latest research on TRE in adults with metabolic syndrome. We will explore how to implement TRE and its various benefits. Dr. Manoogian will also share insights on using the myCircadianClock app in her clinical trials to track TRE and other circadian metrics. For more information, you can visit the myCircadianClock website at www.mycircadianclock.org. If you are interested in participating in a Type 2 Diabetes and TRE study, please get in touch with Dr. Manoogian at preventivecvresearch@health.ucsd.edu. Her latest study was published in the Annals of Internal Medicine: (https://pubmed.ncbi.nlm.nih.gov/39348690/). Thank you for tuning in. Time-Restricted Eating in Adults with Metabolic Syndrome: A Randomized Control Trial https://www.acpjournals.org/doi/10.7326/M24-0859 Guest: Dr. Emily Manoogian Hillblom Fellow, Staff Scientist at the Salk Institute for Biological Studies X (Twitter): @EmilyManoogian Clinical Trials with Dr. Pam Taub: https://cardiology.ucsd.edu/research/labs/taub/research/clinical-trials.html#TRE-x-T2D-Study myCircadianClock website: Participate in a Type 2 Diabetes Study by emailing: preventivecvresearch@health.ucsd.edu Host: Dr. Satchin Panda X (Twitter): @SatchinPanda https://x.com/SatchinPanda Instagram: @satchin.panda https://www.instagram.com/satchin.panda/ Links: Donations: https://panda.salk.edu/giving/ Research: https://www.salk.edu/scientist/satchidananda-panda/ More science: https://mycircadianclock.org/ | |||
02 Jul 2024 | Bente Klarlund Pedersen. "Exercise as medicine." Performance Around The Clock episode 17 | 00:35:44 | |
Episode 17 of the Performance Around The Clock podcast comes from the Cell Symposia meeting on Exercise Metabolism in Lisbon. We were honored to host Dr. Bente Klarlund Pedersen and to talk about her brilliant career from her seminal research on myokines to "exercise as medicine". Dr. Pedersen also tells us about how she uses her knowledge of exercise to educate the public and effect policy changes.Guest:Dr. Bente Klarlund PedersenDirector of Centre for Physical Activity Research (CFAS)https://www.inflammation-metabolism.dk/X (formerly Twitter): @benteklarlundphttps://x.com/benteklarlundpHost:Dr. Satchin PandaX (formerly Twitter): @SatchinPandahttps://x.com/SatchinPandaInstagram: @satchin.pandahttps://www.instagram.com/satchin.panda/Links:Donations: https://panda.salk.edu/giving/Research: https://www.salk.edu/scientist/satchidananda-panda/More science: https://mycircadianclock.org/ | |||
12 Jun 2024 | Frank Scheer - sleep. Performance Around The Clock episode 3. | 01:39:14 | |
In episode 3 of this podcast, sleep and circadian rhythm expert, professor Frank Scheer discusses how our internal body clocks regulate physiology and behaviors in a 24-hour cycle. He explains how measures like dim light melatonin onset and cortisol rhythms provide insights into circadian timing. The discussion covers how factors like light exposure, meal timing, and sleep impact circadian rhythms and health. Dr. Scheer shares research on misaligning behaviors and physiology through social jet lag, night shifts, and mistimed eating. He suggests strategies like optimizing meal timing and light exposure to realign circadian rhythms. Overall, the discussion highlights how adjusting daily behaviors can improve circadian alignment, metabolism, mood, and wellbeing. Enjoy. Guest: Dr. Frank Scheer Professor of Medicine, Brigham and Women's Hospital Division of Sleep and Circadian Disorders at Harvard X (formerly Twitter): @harvardsleepmed Host: Dr. Satchin Panda X (formerly Twitter): @SatchinPanda https://twitter.com/SatchinPanda Instagram: https://www.instagram.com/satchin.panda/ Links: Donations: https://panda.salk.edu/giving/ Research: https://www.salk.edu/scientist/satchidananda-panda/ More science: https://mycircadianclock.org/ | |||
17 Jan 2025 | Mukesh Bansal - digital commerce, wellness and technology. Performance Around the Clock episode 28. | 00:44:23 | |
The Performance Around the Clock podcast episode 28 features special guest Mukesh Bansal. Bansal is a visionary entrepreneur in the fields of digital commerce, wellness and technology. An IIT Kanpur graduate, Bansal's journey began with Myntra, an online fashion retailer that revolutionized apparel shopping in India. His vision extended beyond e-commerce, leading him to co-found Cure.fit, a health and wellness platform. Bansal's impact is further amplified through his venture studio, MerakiLabs, where he supports innovative startups including notable companies like Skyroot Aerospace and Groww. As an avid learner and reader, he put his insights to paper with books like "No Limits," and “Hacking Health”. Join us for an enlightening conversion with Bansal on his career and insights into wellness. If you like this episode, please like, follow or subscribe. Thank you for listening. Guest: Mukesh Bansal X (Twitter): https://x.com/mukeshbansal06 Sparx podcast: https://www.youtube.com/@sparxbymukeshbansal No Limits: https://www.amazon.com/No-Limits-Science-High-Performance-ebook/dp/B0B5LCRC8D Hacking Health: https://www.amazon.com/Hacking-Health-Only-Youll-Healthiest/dp/0670097136 Host: Dr. Satchin Panda X (Twitter): @SatchinPanda https://x.com/SatchinPanda Instagram: @satchin.panda https://www.instagram.com/satchin.panda/ Links: Donations:https://panda.salk.edu/giving/ Research:https://www.salk.edu/scientist/satchidananda-panda/ More science:https://mycircadianclock.org/ |