Neurology® Podcast (American Academy of Neurology)

Dr. Stacey Clardy talks with Dr. P. James B. Dyck about his paper on the incidence of lumbrosacral radiculoplexus neuropathy and association with diabetes mellitus.

Dr. Jeff Ratliff talks with Dr. Raúl Martínez-Fernández about the long-term outcome of unilateral FUS-STN treatment for Parkinson disease.

Read the related article in Neurology.

Disclosures can be found at Neurology.org.

In the first part of the podcast, Dr. Jason Crowell discusses the business of Alzheimer disease and how to approach teaching patients about aducanumab with Dr. Jason Karlawish. In the second segment, Dr. Jennifer Bickel talks with Dr. Eric Kaiser about the contribution of melanopsin and cone signals to light-induced reflexive eye closure in migraine.

The October Neurology Recall highlights Dr. Justin Abbatemarco’s four-part series on autoimmune encephalitis from August 2023. The episode begins with Dr. Josep Dalmau discussing relevant updates and ongoing/upcoming research around autoimmune encephalitis. The next episode discusses the practical approach to testing for auto antibodies in autoimmune encephalitis with Drs. Drs. Sarosh Irani and John Soltys. The episode continues with Drs. Eoin Flanagan and Grace Gombolay helping expand the differential diagnosis in autoimmune encephalitis cases. The October Recall concludes with Dr. Maarten Titulaer talking about the importance of longitudinal care for patients with autoimmune encephalitis.

Related Links: 

Autoimmune Encephalitis Series: Advancing the Science Trials in ALS - https://directory.libsyn.com/episode/index/id/27682701 Autoimmune Encephalitis Series: A Rationale Approach to Diagnostics and Interpretation - https://directory.libsyn.com/episode/index/id/27712707 Autoimmune Encephalitis Series: Expanding the Differential - https://directory.libsyn.com/episode/index/id/27747390 Autoimmune Encephalitis Series: The Importance of Longitudinal Care - https://directory.libsyn.com/episode/index/id/27901296

Dr. Tesha Monteith talks with Dr. Michel Ferrari about the lessons from the first gene to novel targets and mechanisms of migraines.

Read the related article in PubMed.

Disclosures can be found at Neurology.org.

Dr. Stacey Clardy talks with Aaron Baldwin about how access to genetic testing may vary based on various factors such as race, ethnicity, sex, socioeconomic status, and insurance status.

Read the related article in Neurology. 

Disclosures can be found at Neurology.org.

Dr. Derek Stitt talks with Dr. Adam de Havenon about the burden of neurologic health care and incident neurologic diagnoses in the year after COVID-19 vs influenza.

Read the related article in Neurology. 

This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information.

Disclosures can be found at Neurology.org.

Dr. Halley Alexander talks with Dr. Valérie van Hezik-Wester about whether people living with severe medically refractory epilepsy (PSRE) benefit from a seizure dog.

Read the related article in Neurology. 

Disclosures can be found at Neurology.org. 

Dr. Jeff Ratliff talks with Dr. Wilson Abdo about prolonged unconsciousness in COVID-19.

Dr. Stacey Clardy talks with Dr. W. Oliver Tobin about histiocytic diseases affecting the CNS. 

This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information.

Dr. Farrah Mateen talks with Dr. Deanna Saylor about proposed competencies that can serve as a basis for global neurology training programs.

Read the related article in Neurology.

Disclosures can be found at Neurology.org.

In the first segment, Dr. Noah Kolb talks with Dr. Amanda Guidon about her paper on varied phenotypes and management of immune checkpoint inhibitor associated neuropathies. In the second part of the podcast, Dr. Stacey Clardy focuses her discussion with Dr. Mike R. Wilson on clinical metagenomic sequencing for diagnosis of meningitis and encephalitis. Read the full NEJM article here: https://www.nejm.org/doi/full/10.1056/NEJMoa1803396.

Disclosures can be found at Neurology.org.

CME Opportunity: Listen to this week’s Neurology Podcast and earn 0.5 AMA PRA Category 1 CME Credits™ by answering the multiple-choice questions in the online Podcast quiz.

In the concluding segment of this two-part series, Dr. Justin Abbatemarco talks with Dr. Jennifer L. Orthmann-Murphy about genetic leukodystrophies and the increasing recognition of these disorders in adult neurology, the importance of genetic testing, and the evolving treatment landscape. 

Read the related articles in Neurology and CHS Perspectives. 

Disclosures can be found at Neurology.org.

In this first episode of our three-part series, Prof. Jon Stone talks with Drs. Selma Aybek, David Perez, and Sarah Lidstone about FND diagnosis and exploring new phenotypes.

Related Links:

• FND Society at fndsociety.org
• FND guide for patients at neurosymptoms.org
• FND Hope at fndhope.org

Visit NPUb.org/Podcast for associated article links.

This episode was sponsored by the ExTINGUISH Trial for NMDAR Encephalitis: Call 844-4BRAIN5 to refer patients.

Dr. Neha Dangayach talks with Drs. Susanne Muehlschlegel and Adeline Goss about characterizing the prognostic language clinicians use in critical neurologic illness.

Read the related article in Neurology.

Visit NPUb.org/Podcast for associated article links.

In this month's replay of past episodes, we cover treatment and management of status epilepticus, featuring discussion between Dr. Halley Alexander and Dr. Michael Sperling. For discussion questions for your next journal club talk, go here. 

In the first segment, Dr. Jason Crowell talks with Dr. Daniel Claassen about his Neurology: Genetics paper on genotyping single nucleotide polymorphisms for allele-selective therapy in Huntington disease. In the second part of the podcast, Dr. Jeffrey Ratliff focuses his discussion with Dr. Roseanne Dobkin on telephone-based CBT for depression in patients with Parkinson disease.

Disclosures can be found at Neurology.org.

No CME this week: Interviews based on articles from Neurology: Clinical Practice®, Neurology® Genetics, and Neurology® Neuroimmunology & Neuroinflammation are excluded from the CME program.

Dr. Halley Alexander talks with Dr. Genevieve Rayner and Eliza Honybun about the relationship between prenatal antiseizure medication exposure and adverse postnatal neurodevelopmental outcomes. 

Read the related article in Neurology.

Disclosures can be found at Neurology.org.

Dr. Jeff Ratliff talks with Prof. Andrew Siderowf about the assessment of heterogeneity among participants in the Parkinson progression markers initiative cohort using α-synuclein seed amplification.

Read the related article in The Lancet Neurology.

Disclosures can be found at Neurology.org.

Dr. Jason Crowell talks with Dr. Christopher Gibbons about the need for accurate diagnostic and prognostic biomarkers for MSA and its differentiation from other synucleinopathies.

Read the related article in Neurology.

Disclosures can be found at Neurology.org.

In the first segment, Dr. Jeff Burns talks with Dr. Yvette Sheline about her paper on the Effect of escitalopram on CSF Aβ. In the second part of the podcast, Dr. Stacey Clardy speaks with Dr. Elizabeth Finger about her article on the neural effects of oxytocin on frontotemporal dementia, also from this week’s issue.   

Disclosures can be found at Neurology.org.

CME Opportunity: Listen to this week’s Neurology Podcast and earn 0.5 AMA PRA Category 1 CME Credits™ by completing the online Podcast quiz.

Dr. Stacey Clardy receives an update from Dr. Pushpa Narayanaswami on the management of myasthenia gravis.

Celebrate the 70th Anniversary of Neurology® with Part II of a series of interviews on the history of the journal featuring editors-in-chief Drs. José Merino, Robert Gross, John Noseworthy, and Robert Griggs as well as Podcast Editors Drs. Ted Burns and Stacey Clardy.

Dr. Jason Crowell talks with Dr. Karlo Lizarraga and Dr. Angela Hewitt about neurophysiological biomarkers to optimize deep brain stimulation in movement disorders. 

This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information.

Dr. Justin Abbatemarco talks with Dr. Géraldine Androdias about the impact of immune checkpoint inhibitors on the course of multiple sclerosis.

Read the related article in Neurology: Neuroimmunology and Neuroinflammation. 

Disclosures can be found at Neurology.org.

In this episode, dedicated to the memory of the 35th president of the AAN, Dr. Ralph Sacco, Dr. Tesha Monteith talks with Dr. Mitch Elkind and Dr. Orly Avitzur, as they talk about the life, legacy, and incredible achievements of Dr. Ralph Sacco for all that he touched and for those left to be inspired. 

Read Dr. Sacco's In Memoriam article.

Disclosures can be found at Neurology.org.

Prof. Jon Stone talks with Dr. Laura Strom and Meagan Watson about changes in total emergency department and inpatient visits and costs before and after referral to a specialized, comprehensive functional seizure treatment clinic.

Read the related article with Neurology^® Clinical Practice.

Disclosures can be found at Neurology.org. 

Dr. Jeff Ratliff talks with Dr. Chris Gibbons about the use of skin biopsies to detect phosphorylated α-synuclein in individuals with synucleinopathies such as Parkinson disease, multiple system atrophy, dementia with Lewy bodies, and pure autonomic failure.

Read the related article in JAMA. 

Disclosures can be found at Neurology.org.

Dr. Jason Crowell talks with Dr. Manu Sharma about the genome-wide association of age-at-onset in Parkinson disease. Read the full article in Neurology.

This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information.

In the first part of our two-part series on neurodegeneration in professional football players, Dr. Shuvro Roy talks with Dr. Ann McKee about the high incidence and mortality rates of amyotrophic lateral sclerosis (ALS) in NFL athletes.

For more information on the VA-BU-CLF Brain Bank at the Boston University CTE Center, including brain donation inquiries, click here.

The December 2021 replay of past episodes showcases a selection of interviews regarding the diagnosis and management of stroke. This episode features Dr. Andy Southerland and Will Rondeau in conversation with Drs. Seemant Chaturvedi, Lee Schwamm, Jyri Virta, and Sidsel Hastrup, offering listeners a review across the field of vascular neurology.

Dr. Justin Abbatemarco talks with Drs. Michael R. Wilson and John Pluvinage about their discovery of anti-CD320 antibodies in patients with neurologic manifestations of B12 deficiency and discuss the potential implications for diagnosis and treatment. 

Read the related article in Science. 

Disclosures can be found at Neurology.org.

Dr. Gordon Smith talks with Dr. Haya Bishara about the association between GBS and both SARS-CoV-2 infection and the COVID-19 vaccine.

Read the related article in Neurology.

Disclosures can be found at Neurology.org.

Dr. Jessica Ailani talks with Dr. Aaron Kesselheim and Leigh Sharpless about the endpoints used in trials supporting the US FDA approval of medications treating migraines. 

Read the related article in Neurology.

This episode was sponsored by the ExTINGUISH Trial for NMDAR Encephalitis: Call 844-4BRAIN5 to refer patients.

Dr. Jeff Ratliff talks with Dr. Eduardo De Pablo-Fernández about the strengths of DAT imaging in diagnosing patients with Parkinsonian disorders.

Read the related article in Neurology. 

Disclosures can be found at Neurology.org.

In the second part of a 2-part interview, Dr. Bob Gross discusses changes to the journal and publishing as well as some controversies and challenges as Editor-in-Chief of Neurology.

Dr. Halley Alexander talks with Dr. Wyatt Bensken about the difference in antiseizure medications between racial and ethnic groups among people with epilepsy.

Read the related article in Neurology: Clinical Practice. 

Disclosures can be found at Neurology.org.

Dr. Jason Crowell talks with Prof. Bastiaan Bloem about the latest developments in biomarkers and treatments for movement disorders, which have been described in numerous research papers from 2022. 

Read the related article in The Lancet.

Disclosures can be found at Neurology.org.

Dr. Andy Southerland talks with Dr. Seemant Chaturvedi about recent trials presented at the European Stroke Organization Conference.

Show references: 

Tenecteplase for Ischemic Stroke at 4.5 to 24 Hours without Thrombectomy 

Rationale and Design of Tenecteplase Reperfusion Therapy in Acute Ischaemic Cerebrovascular Events III (TRACE III)

Colchicine for Prevention of Vascular Inflammation in Non-CardioEmbolic Stroke (CONVINCE)

Intensive Ambulance-Delivered Blood- Pressure Reduction in Hyperacute Stroke

This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information.

Disclosures can be found at Neurology.org.

Dr. Jeff Burns discusses the amyloid hypothesis and the challenges clinicians face in navigating discussions on the use of aducanumab for Alzheimer disease with Dr. Erik Musiek.

Dr. Gordon Smith talks with Drs. Shahar Shelly and Teerin Liewluck about the correlation between CMAP duration and myosin loss and their effect on mortality by comparing between patients with CIM with and without myosin loss.

Read the related article in Neurology. 

Disclosures can be found at Neurology.org.

Dr. Jason Crowell continues his discussion with Dr. Sonia Vallabh on a profile of prion disease, in the second part of a 2-part interview. 

Dr. Andy Southerland talks with Dr. Jonathan Coutinho about the accuracy of using EEG in the detection of large vessel occlusion stroke in prehospital settings. 

Read the related article in Neurology.

Disclosures can be found at Neurology.org 

Dr. Tesha Monteith talks with Drs. Messoud Ashina and Andrea Cipriani about all licensed drug interventions as oral monotherapy for the acute treatment of migraine episodes in adults.

Read the related article in the BMJ.

Disclosures can be found at Neurology.org.

Dr. Justin Abbatemarco talks with Dr. Aurora Pujol about diagnosing genetic white matter disorders by singleton whole-exome and whole-genome sequencing using interactome-driven prioritization. Read the full article in Neurology.

Dr. Andy Southerland talks with Dr. Adam Rodman about the implications of large language models in clinical reasoning and diagnostics.

Read the related article on arXiv. 

Disclosures can be found at Neurology.org.

Dr. Farrah Mateen talks with Dr. Richard Benson about the NINDS health equity efforts and the implications of the new strategic plan for research.

Read the related supplement in Neurology. 

Visit NPUb.org/Podcast for associated article links.

In the first segment, Dr. Jeffrey Ratliff talks with Dr. Elizabeth Matthews about her paper on super-refractory status epilepticus. In the second part of the podcast, Dr. Jason Crowell speaks with Matthew Futterman about hit New York Times article on neurologic sequela in sledding athletes. Read the NYT article here: https://nyti.ms/3mNBlhE. 

Disclosures can be found at Neurology.org.

CME Opportunity: Listen to this week’s Neurology Podcast and earn 0.5 AMA PRA Category 1 CME Credits™ by completing the online Podcast quiz.

Dr. Kathryn Nevel talks with Dr. Linda Liau about the use of autologous tumor lysate-loaded dendritic cell vaccination for the treatment of newly diagnosed and recurrent glioblastoma.

Read the related article in JAMA Oncology.

Disclosures can be found at Neurology.org.

Dr. Jeff Ratliff talks with Dr. Maureen Leehey about the short-term efficacy and tolerability of high-CBD/low-THC cannabis extract on the motor symptoms in patients with Parkinson disease. 

Read the related article in the International Parkinson and Movement Disorder Society. 

This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information.

Disclosures can be found at Neurology.org.

Dr. Amy Gelfand talks with Dr. Matthew Bender about the possible association between glymphatic outflow and extent of transverse sinus stenosis in patients with intracranial hypertension.

Read the related article in Neurology.

Disclosures can be found at Neurology.org.

In the final part of this three-part series, Dr. Stacey Clardy talks with Drs. Elisabeth Bik and Matthew Schrag about the challenges posed by AI in generating fraudulent research, the importance of cultural solutions to uphold scientific integrity, and the need for modernized data management practices in research.

Read the related article in Undark. 

Disclosures can be found at Neurology.org.

Dr. Halley Alexander talks with Dr. Emanuele Cerulli Irelli about the research on seizure recurrence in women with idiopathic generalized epilepsy who switch from valproate to another medication.

Read the related article in Neurology.

This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information.

Disclosures can be found at Neurology.org.

Dr. Avindra Nath provides a special report on what clinicians need to know about neurologic symptoms and complications of COVID-19.

For a clearing house of neurology related information on the coronavirus go to AAN.com/COVID19 to stay up-to-date.

The April 2023 replay of past episodes showcases our November 2022 headache series hosted by Dr. Tesha Monteith. The first episode features a conversation with Dr. Peter Goadsby about the value offered by headache classifications, followed by an interview with Drs. Simona Sacco and Jessica Ailani about an update on migraine guidelines. Next in the episode, Dr. Lars Edvinsson discusses CGRP and the role of sex hormones. The April recall closes out with an interview with Dr. Rebecca Burch about hot topics in headache medicine.

Related Podcast Links:

November Headache Series: Increasing the Value of Neurology Through Headache Classifications: http://directory.libsyn.com/episode/index/id/24894771

November Headache Series: Update on Migraine Guidelines: https://directory.libsyn.com/episode/index/id/25083906 

November Headache Series: CGRP and Role of Sex Hormones: https://directory.libsyn.com/episode/index/id/24967986 

November Headache Series: Hot Topics in Headache Medicine: https://directory.libsyn.com/episode/index/id/25042293 

Disclosures can be found at Neurology.org

Dr. Tesha Monteith talks with Dr. Elizabeth Loder about her editorial on the gender pay gap in academic neurology and its impact on women neurologists as well as the field at large. Read the full article in Neurology.

This month’s Delayed Recall highlights episodes on developments and scandals related to genetic testing and technology in neurology. Dr. Jason Crowell and Dr. Josephine Johnston of the Hastings Center start the show discussing the ethical and philosophical implications of gene editing., which first aired on December 18th, 2018. The next segment, also from December 18th, has Dr. Stacey Clardy and Dr. Stefan Pulst focusing on the scientific and societal impact of the recent first reported gene editing using the CRISPR technology. Following this segment is one from December 3rd and finds Dr. Jeff Waugh talking with Dr. Saadet Andrews about her paper on the genetic landscape of pediatric movement disorders and management implications. This episode continues with an interview on a Neurology: Genetics on the long journey to diagnosis for patients with mitochondrial disease between Dr. Jason Crowell and Drs. John L.P. Thompson and Michio Hirano from April 3rd, 2018. The episode wraps up with a talk between Dr. Jeffrey Ratliff and Dr. Thomas Bird from March 20th, 2018, on Dr. Bird’s Neurology: Clinical Practice paper on the benefits and limitations of exome sequencing to identify hereditary ataxias.

This month’s replay of past episodes showcases a selection of interviews concerning the FDA approval of aducanumab for the treatment of Alzheimer disease from clinical, political, and economic perspectives. The selected interviews feature conversations between Dr. Gregg Day and Pam Belluck, Dr. Jeff Burns and Dr. Ron Peterson, Dr. Jason Crowell and Dr. Steve Pearson, and Dr. Jeff Burns and Dr. Daniel Gibbs.

Dr. Justin Abbatemarco talks with Dr. Ahmad Nehme about the complexities of diagnosing and differentiating between cerebral amyloid angiopathy-related inflammation and biopsy-positive primary angiitis of the central nervous system.

Read the related article in Neurology.

Disclosures can be found at Neurology.org.

Dr. Gregg Day talks with Dr. Avi Nath, Clinical Director of the National Institute of Neurological Disorders and Stroke (NINDS), about COVID brain fog and other cognitive syndromes. Read the full article referenced in this podcast in the Washington Post.

In the October 2024 replay features four episodes on approaches to clinical diagnosis of parkinsonism. The episode starts off with Dr. Colin Hoy discuss the concept of prodromal Parkinson disease and the ethical considerations surrounding its diagnosis. The episode leads into a conversation with Dr. Chris Gibbons discussing skin biopsies to detect phosphorylated α-synuclein. In the third episode Drs. Michiko K. Bruno and Lawrence Golbe about a practical diagnostic algorithm for atypical parkinsonian disorders Drs. Michiko K. Bruno and Lawrence Golbe discuss a practical diagnostic algorithm for atypical parkinsonian disorders. The episode concludes with Dr. Eduardo De Pablo-Fernández talking about the strengths of DAT imaging in diagnosing patients with Parkinsonian disorders.

Previous Podcasts:

The Ethical Landscape of Prodromal Parkinson Disease

Skin Biopsy Detection of Phosphorylated α-Synuclein

General Neurologist's Practical Diagnostic Algorithm for Atypical Parkinsonian Disorders

Interpreting DAT Imaging Results in the Clinical Context

Article Links:

The Ethical Landscape of Prodromal Parkinson Disease 

Skin Biopsy Detection of Phosphorylated α-Synuclein in Patients With Synucleinopathies

A General Neurologist's Practical Diagnostic Algorithm for Atypical Parkinsonian Disorders 

Neuropathologic Validation and Diagnostic Accuracy of Presynaptic Dopaminergic Imaging in the Diagnosis of Parkinsonism

Disclosures can be found at Neurology.org.

Dr. Derek Stitt talks with Dr. Miranda M. Wan about improving training and public awareness to optimize palliative care for patients with neurologic conditions.

Read the related article in Neurology: Clinical Practice.

Disclosures can be found at Neurology.org.

In the second episode of our three-part series, Prof. Jon Stone talks with Drs. Selma Aybek, David Perez, and Sarah Lidstone about how and why FND occurs.

Related Links:

• FND Society at fndsociety.org
• FND guide for patients at neurosymptoms.org
• FND Hope at fndhope.org

Visit NPUb.org/Podcast for associated article links.

Disclosures can be found at Neurology.org.

Dr. Tesha Monteith talks with Prof. Rigmor Højland Jensen about psychiatric co-morbidities in patients with idiopathic intracranial hypertension. Read the full article in Neurology.

Dr. Andy Southerland talks with Dr. Seemant Chaturvedi about the latest findings from the International Stroke Conference, focusing on advancements in stroke treatment and recovery.

Read more about the ESCAPE-MeVO trial.  

Read more about the Distal trial.

Read more about the ANGEL-TNK trial.

Read more about the PRESTIAGE-AF trial. 

Read more about the TRANSPORT2 trial.

Disclosures can be found at Neurology.org.

Dr. Jeffrey Ratliff talks with Dr. Anneleen Berende about her paper on the effect of prolonged antibiotic treatment on cognitive performance in patients with Lyme borreliosis. Dr. Andrew Southerland focuses his interview with Dr. Stephen Klasko on hospitals of the future, following a panel at the World Economic Forum in Davos, Switzerland. The article can be found here: https://www.statnews.com/2019/01/26/dispatch-from-davos-future-hospitals/.

The March 2025 replay features four previously released episodes focused on peripheral neuropathy and radiculopathy. The episode begins with Dr. Anne Oaklander discussing the association between long COVID and the development of polyneuropathy affecting small-fiber axons. This is followed by another interview with Dr. Oaklander, where she shares key takeaways for clinicians regarding the management of small-fiber neuropathy. The third segment features Drs. Raymond Price and Brian Callaghan discussing practice guidelines for painful diabetic neuropathy. The episode concludes with Dr. Carmel Armon addressing the efficacy of epidural steroid injections in treating cervical and lumbar spinal stenosis and radiculopathies.

Podcast Links:

Peripheral Neuropathy and Prolonged COVID 

Relapsing-Remitting Immunotherapy Responsive SFN 

Practice Guidelines for Painful Diabetic Neuropathy

Epidural Steroids for Cervical and Lumbar Radicular Pain and Spinal Stenosis

Article Links: 

Peripheral Neuropathy Evaluations of Patients With Prolonged Long COVID 

Relapsing-Remitting Immunotherapy Responsive Small-Fiber Neuropathy 

Epidural Steroids for Cervical and Lumbar Radicular Pain and Spinal Stenosis Systematic Review Summary 

Disclosures can be found at Neurology.org.

Dr. Gregg Day talks with Prof. Ronald Postuma about the conflicting evidence regarding the association between seasonal changes and daylight-saving time and sleep disorders. Read the related article in Neurology.

For links to articles and previous podcast episodes, please visit NPUb.org/Podcast.

This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information.

In the first segment, Dr. Stacey Clardy talks with Dr. Mathias Buron about his paper addressing the comparative effectiveness of teriflunomide and dimethyl fumarate. In the second part of the podcast, Dr. Jason Crowell focuses his interview with Dr. Joanna Hellmuth on the rise of pseudomedicine for dementia and brain health.

The first segment features Dr. Stacey Clardy in conversation with 2021 Ted Burns Humanism in Neurology Award recipient Dr. John Quinlan. In the second part of the podcast, Dr. Andy Southerland discusses the risk of readmission following inpatient admission for reversible cerebral vasoconstriction syndrome with Dr. Santiago Ortega-Gutierrez.

The January 2022 replay of past episodes showcases a selection of interviews regarding the diagnosis and effects of traumatic encephalopathy syndrome (TES) and concussions. This episode features Dr. Alex Menze in conversation with Dr. Robert Stern, Dr. Nathan Churchill, and Prof. Antonio Belli, offering listeners a comprehensive understanding of the diagnosis and management of head trauma.

Dr. Jeff Ratliff talks with Dr. Vikas Kotagal about how neighborhood socioeconomic factors vary among individuals with different types of clinical movement disorders. 

Read the related article in Neurology: Clinical Practice.

Disclosures can be found at Neurology.org.

Dr. Tesha Monteith talks with Dr. Cecilia Hvitfeldt Fuglsang about the effects of migraine and PIH on the risk of stroke and myocardial infarction.

Read the related article in Neurology.

Disclosures can be found at Neurology.org.

In the first segment, Dr. Kristen Heinan talks with Dr. Barbara Weissman about her Neurology: Clinical Practice paper on recommendations for neurologists on the CDC’s Guideline on Pediatric Mild Traumatic Brain Injury. In the second part of the podcast, Dr. Will Rondeau focuses his discussion with Dr. Geoffrey Donnan on his NEJM paper on thrombolysis guided by perfusion Imaging up to 9 hours after onset of stroke. You can read the paper here: https://www.nejm.org/doi/pdf/10.1056/NEJMoa1813046.  

Dr. Teshamae Monteith talks with Dr. Ralph Sacco about health disparities and inequities in light of COVID-19. 

Dr. Scott Mintzer talks with Dr. Adithya Sivaraju about predicting outcomes among patients undergoing intracranial EEG. Read the full article in Neurology.

This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information.

The September 2021 replay of past episodes showcases a selection of interviews focused on the management of myasthenia gravis. The selected interviews feature Dr. Ted Burns and Dr. Stacey Clardy in conversation with Drs. Gil Wolfe, Joseph Shrager, and Pushpa Narayanaswami before closing with before closing with notes from Dr. Ted Burns on MuSK myasthenia gravis.

Dr. Gregg Day talks with Dr. Niklas Mattsson-Carlgren about the correlation of cerebrospinal fluid biomarkers with autopsy-confirmed Alzheimer disease and frontotemporal lobar degeneration. Read the full article in Neurology.

Call to Action for Neurologists. On this week's episode, Dr. Tesha Monteith talks with Dr. Peter Goadsby about headache classifications as part of the November Headache Series.

This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information.

Disclosures can be found at Neurology.org.

Dr. Stacey Clardy talks with Dr. Geoff Ling about his thoughts on rapid-fire mortar shooting and more broadly, how he goes about identifying what veterans have been exposed to and treating veterans in the clinic.

They also discussed a little bit about a recently published article in the New York Times titled, "A Secret War, Strange New Wounds, and Silence from the Pentagon." 

Disclosures can be found at Neurology.org.

Dr. Halley Alexander talks with Dr. Vineet Punia about factors influencing the decision to continue or discontinue anti-seizure medications at discharge for patients hospitalized with acute symptomatic seizures. 

Read the related article in JAMA.  

Disclosures can be found at Neurology.org.

Dr. Maisha Robinson talks with Dr. Monica Lemmon about a framework to guide clinicians in communicating information about neurologic prognosis.

Read the related article in Neurology. 

Disclosures can be found at Neurology.org.

You'll hear the second part of an interview on migraine between Dr. Jason Crowell and Dr. David Watson, focusing on special patient populations in management of migraine.

The June 2023 replay of past episodes showcases a selection of interviews regarding the biomarker discovery in Parkinson disease. This episode begins with an overview of the latest in Parkinson’s research, including biomarker development with Dr. Bas Bloom. The episode continues with an interview with Dr. Lucilla Parnetti about the clinical application of α-synuclein seed amplification, leading into an interview with Prof. Andrew Siderowf about seed amplification in PD in the PPMI cohort. The June Neurology Recall concludes with an interview with Dr. Christopher Gibbons on skin α-synuclein in MSA and PD.

Related Podcast Links:

Biomarker and Treatment Development in Movement Disorders: https://directory.libsyn.com/episode/index/id/26775207

Alpha-synuclein Amplification for Disease Diagnosis: https://directory.libsyn.com/episode/index/id/23923047

α-Synuclein Seed Amplification in a Large Parkinson Cohort: https://directory.libsyn.com/episode/index/id/26961315

Skin α-Synuclein In MSA and PD: https://directory.libsyn.com/episode/index/id/26499948

Related Article Links: 

Research in Movement Disorders in 2022: A New Era of Biomarker and Treatment Development: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(22)00494-X/fulltex

Synuclein Seed Amplification Assays for Diagnosing Synucleinopathies: The Way Forward: https://n.neurology.org/content/99/5/195

Assessment of Heterogeneity Among Participants in the Parkinson's Progression Markers Initiative Cohort Using _-Synuclein Seed Amplification: A Cross-Sectional Study: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(23)00109-6/fulltext

Cutaneous _-Synuclein Signatures in Patients With Multiple System Atrophy and Parkinson Disease: https://n.neurology.org/content/100/15/e1529

Disclosures can be found at Neurology.org

In the first segment, Dr. Stacey Clardy talks with Dr. Caterina Lapucci about her paper addressing how much periventricular lesions assist in distinguishing migraine with aura from CIS. In the second part of the podcast, Dr. Jason Crowell focuses his interview with Sarah Karlin-Smith and Sarah Owermohle from Politico on drug pricing.

Dr. Tesha Monteith talks with Drs. Simona Sacco and Jessica Ailani about migraine guidelines as part of the November Headache Series.

This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information.

Disclosures can be found at Neurology.org.

Dr. Vikram Karnik talks with Dr. Kate Wyman-Chick about distinguishing prodromal dementia with Lewy bodies from prodromal Alzheimer disease, the importance of early diagnosis, and the implications for clinical practice.

Read the related article in Neurology: Clinical Practice.

Disclosures can be found at Neurology.org.

Dr. Deanna Saylor talks with Prof. Mayowa Owolabi about reducing the global burden of stroke.

Read the related article in Lancet Neurology. 

Dr. Tesha Monteith talks with Dr. Barbara Decker about maternal obstetric complications and non-elective postpartum readmissions in women with prior stroke, migraine, multiple sclerosis, and myasthenia gravis. Read the full article in Neurology.

Dr. Stacey Clardy discusses the prognostic factors and efficacy of immunosuppressive treatments for spinal cord sarcoidosis with Dr. Antoine Gavoille. Read the full article in Neurology.

Dr. Andy Southerland talks with Dr. Cheryl Bushnell about the significance of these guidelines, essential messages for clinicians, lifestyle factors influencing stroke risk, unique considerations for women’s health, and the necessity to bridge knowledge gaps in stroke prevention.

Read the 2024 Guideline for the Primary Prevention of Stroke.

Disclosures can be found at Neurology.org.

In the first segment, Dr. Jeffrey Ratliff talks with Dr. Tamara Milka Pringsheim about her practice guideline recommendations summary paper on the treatment of tics in people with Tourette syndrome and chronic tic disorders. In the What's Trending segment, you'll hear the second part of an interview between Dr. Jason Crowell and New York Times staff writer Pam Belluck on CRISPR and gene editing.

The November 2023 replay of past episodes showcases five interviews on topics in stroke. The episode begins with an interview with Dr. Imogene Scott on prehospital telestroke vs paramedic scores to accurately identify stroke reperfusion candidates. The episode continues with an interview with Dr. David Seiffge on the use of oral anticoagulants on ischemic stroke. The next interview is with Dr. Alejandro Rabinstein and Hassan Kobeissi on comparing outcomes between CTP and NCCT for endovascular therapy selection in the late therapeutic window. The fourth interview is with Dr. Thanh Nguyen discussing whether dual antiplatelet therapy is non-inferior to intravenous thrombolysis among patients with minor non-disabling acute ischemic stroke. The November Recall concludes with Dr. Seemant Chaturvedi discussing this year's European Stroke Organization Conference and pivotal trials that were presented during the conference.

Related Podcast Links:

Pre-Hospital Evaluation of Acute Stroke: EMS vs Telemed: https://directory.libsyn.com/episode/index/id/24928863

Intravenous Thrombolysis in Patients With Ischemic Stroke and Recent Ingestion of Direct Oral Anticoagulants: https://directory.libsyn.com/episode/index/id/25736865 

CT Perfusion vs CT for Late Window Stroke Thrombectomy: https://directory.libsyn.com/episode/index/id/26673237

Dual Antiplatelet Therapy vs Alteplase for Patients With Acute Ischemic Stroke:  https://directory.libsyn.com/episode/index/id/27455412

Pivotal Stroke Trials Presented at this Year’s ESOC: https://directory.libsyn.com/episode/index/id/27279144

Related Article Links:

Prehospital Telestroke vs Paramedic Scores to Accurately Identify Stroke Reperfusion Candidates: A Cluster Randomized Controlled Trial: https://n.neurology.org/content/99/19/e2125

Intravenous Thrombolysis in Patients With Ischemic Stroke and Recent Ingestion of Direct Oral Anticoagulants: https://jamanetwork.com/journals/jamaneurology/fullarticle/2799622

CT Perfusion vs Noncontrast CT for Late Window Stroke Thrombectomy: A Systematic Review and Meta-analysis: https://n.neurology.org/content/100/22/e2304

Dual Antiplatelet Therapy vs Alteplase for Patients With Minor Nondisabling Acute Ischemic Stroke: The ARAMIS Randomized Clinical Trial: https://jamanetwork.com/journals/jama/article-abstract/2806532

ESOC Plenary: https://2023.eso-conference.org/programme/plenary-highlights/

Disclosures can be found at Neurology.org

Dr. Elizabeth Coon talks with Dr. Valeria Iodice about diagnosing pre-motor multiple system atrophy.

Read the full article in Neurology.

This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information.

Disclosures can be found at Neurology.org.

This month’s Delayed Recall highlights 6 interviews on encephalopathies from the March and April 2013 Delayed Recall episodes. You’ll hear about encephalopathies caused by endocrine disorders, by electrolyte disorders, by liver and kidney failure, and by other organ failure. The other interviews cover encephalopathies caused by systemic disease, such as encephalopathies caused by drugs or miscellaneous causes, including vitamin deficiencies and autoimmune disorders.

This second installment in our two-part series features Dr. Stacey Clardy in conversation with Mary Post, CEO of the American Academy of Neurology.

Our 2023 November Headache series wraps up with Dr. Tesha Monteith talking with Dr. Stewart Tepper about rapid developments in neuromodulation. 

Disclosures can be found at Neurology.org

Dr. Halley Alexander talks with Dr. Ingo Helbig about the use of ketamine for management of neonatal and pediatric refractory status epilepticus.

Read the full article in Neurology.

This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information.

Disclosures can be found at Neurology.org.

In the first segment, Dr. Michelle Mauermann talks with Dr. Bart Jacobs about his paper on current treatment practice of Guillain-Barré syndrome. In the second part of the podcast, Dr. Matthew Harms focuses his discussion with Dr. Guy Rouleau on his Neurology: Genetics paper looking at how somatic expansion of the C9orf72 Hexanucleotide Repeat does not occur in ALS spinal cord tissues.