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DateTitreDurée
22 Apr 2022Celebrating Lab Week: Looking at the Past to Plan for the Future00:21:48

Timestamps:

00:00 Intro

01:30 Why is it important for us to look at our past when planning for our future?

05:37 Sometimes people struggle with celebrating and I think also, maybe some people get nervous about that--taking time to celebrate accomplishments that have been. What’s your take on that? 

07:01 What are one or two aspects of pathology and lab medicine’s past that you are thinking about celebrating this year? 

11:56 How do you see these aspects that you’re celebrating in forming kind of the future projections of success in our field?

14:18 Do you have thoughts for how we might approach this as a healthcare system--attracting bright students into medical laboratory science?

17:22 Is there something that we’ve done that we shouldn’t continue, that we need to change and discontinue--a certain process or way that our laboratory works? 

20:57 Outro

22 Nov 2024AI in Education00:22:01

In this episode of Lab Medicine Rounds, Justin Kreuter, M.D., speaks with career educator Elissa Hall, Ed.D., on the integration and impact of artificial intelligence in graduate medical education, exploring strategies for teaching AI, the importance of critical thinking, and the ethical considerations involved.

Timestamps
0:00 Intro

01:07 Graduate medical education and artificial intelligence

03:20 How to use AI to develop physician skills. 

05:00 Educational strategies for training in AI?

08:21 Training with AI look

12:22 How to be a critical thinker

14:24 Assessment with AI education

17:40 How to use AI in clinical practice 

21:25 Outro

05 Jan 2024Perspectives of a Teaching Assistant00:20:24

In this episode of “Lab Medicine Rounds,” host Justin Kreuter, M.D., engages in a compelling conversation with Lindsey Randall, a third-year medical student, as they discuss her experiences and insights in the role of a teaching assistant. 

00:00 Introduction
01:05 Why did you decide to get involved in teaching in the first place?
02:07 You’ve been teaching in this course, but how has your learning been from this experience of teaching?
05:45 Do you have any thoughts about what you’ve learned about chunking information and sequencing information?
08:01 Could you elaborate on your approach for writing those questions?
10:25 You don’t shy away from questions where there is clearly a “best answer.” Could you talk on why you’ve included those questions intentionally? 
13:14 How do you handle those moments when you don’t know an answer? 
15:45 What advice do you have for those listening who may be interested in developing their teaching skills?

07 Aug 2020COVID-19 Testing Update00:19:55

Time Stamps

00:00 Podcast Intro

00:50 Why does this landscape of COVID testing seem so dynamic? 

03:47 So it sounds like we have two sort of rapid tests that are on the market now. Can we dive into that so that we can appreciate a little bit of the compare and contrast between those two rapid assays?

07:17 What are these unique challenges with regards to sensitivity and specificity when it comes to these rapidly evolving tests?

11:08 Highlighting the connection between laboratory medicine and the clinical practice as it applies to COVID-19 testing.

12:49 What new struggles have emerged when it comes to testing for COVID?

15:15 What’s a thought process that you recommend for folks to think about when people are trying to think about what should I offer in my lab, or how should I offer COVID testing? 

17:25 Dr. Binnicker, if you were king for a day, what would you make happen for COVID testing?

19:09 Outro 

Resources:

Centers for Disease Control and Prevention (CDC)

U.S. Food and Drug Administration (FDA)

19 Mar 2021Toxicology testing for patient care00:23:06

00:00 Intro

00:40 Can you tell us how your roles in these different laboratories support testing for patient care?

03:13 What are the latest developments in your area of clinical laboratory medicine?

07:22 Can you elaborate a little bit about this new approach that you have developed is able to bring both sensitivity and specificity along?

10:55 Putting the interpretation on the form, you are probably experiencing quite a few phone calls with our clinical colleges. Can you talk to us about how those interactions go between the laboratory and clinical professionals?  

15:10 How have your clinical consultations changed, based on feedback you’ve gotten from previous conversations?

18:15 You also serve as Vice Chair for Supply Chain Management in the Department of Laboratory Medicine and Pathology. This has been talked about a lot related to the Sars-Cov-2 pandemic. Do you have any reflections about key lessons you have learned as you try to stay ahead of supply chair issues?

22:06 Can you tell us more about resiliency in relation to supply chain management?

24:42 Outro

14 Feb 2020The Littlest Things in Life - The Burning Sensations of Love: Let's Talk STDs (Part 2)00:12:28

Time Stamps

00:00 Podcast Intro 

00:31 Introduction of Matt Binnicker, Ph.D.

01:07 Can you talk about why it’s so important for people to discuss chlamydia and gonorrhea and why healthcare providers and the general public today need to have a good understanding of the causes of these STDs? 

02:32 So we just spoke to Dr. Rizza about how over the last five years, STDs have risen each year consecutively. Is there any reason why we have an increased incidence over this timeline with these infections?

03:31 How are these diagnosed in the laboratory? How do we actually figure out if you have this or not?

04:22 Those diagnostic processes, do you think those are going to change at all in the future or evolve, or do you think what we have is good?

06:28 So why is important then to have accurate and rapid laboratory test results for chlamydia and gonorrhea? 

07:17 So with regards to the disease itself, if a patient becomes infected how are they managed?

08:50 With drug resistant gonorrhea being in the news so often, the next real concern is how worried should we be about it?

09:58 What should be the big takeaway the audience should get from talking about gonorrhea and chlamydia?

11:45 Outro

15 Dec 2023Celebrating 100 Episodes00:24:43

In this episode of “Lab Medicine Rounds,” host Justin Kreuter, M.D., along with the Lab Medicine Rounds podcast team share their experience on starting an educational podcast and reflecting on past episodes.

Timestamps
00:00 Introduction
01:02 Rick: How did the podcast start up? What was the genesis, how did this all start?
03:05 Dr. Kreuter: How does this work around the podcast all come together? And what’s most surprising about it?
07:03 Rick to Dr. Kreuter: From your standpoint, what do you have to do to prepare for a podcast?
08:48 Rick: What was the overall goal or mission statement of the podcast when you started?
11:14 Rick: What are your takeaways, funny things, things that Dr. Kreuter does that annoys you, or what do you look forward to?
14:02 Dr. Kreuter to Rick: Can you share some of the pointers you give to presenters before we begin recording?
18:15 Rick: What do you think is different from when we started, the first one we did here in this studio, to the 99th one we just finished?
21:18 Rick to Dr. Kreuter: What does the future of the Lab Medicine Rounds podcast hold?
23:57 Outro

20 May 2022Special Episode for Students Who Matched Into Pathology00:54:04

Timestamps:
0:00 Intro

2:00 Coming off a relaxed 4th year, how do you recommend we get back into the study flow for training? 

6:45 Once residency starts and we are working all day and studying in the evenings, do you have recommendations on how to ease back into that? 

9:30 How do you recommend finding a mentor in residency training? How do you know if it’s a good fit or if you need to figure out how to find another mentor? 

13:35 How would you maximize your time on AP rotations? How is this approach different than CP rotations? 

21:22 How do you recommend getting involved in research and residency? If you do find a project you are interested in, how do you approach it if they are not doing a lot of research in that area at the time? 

28:18 How do you mentor your residents on balancing step 3 studying, with pathology studying, and working? 

29:15 What is the role of having research and research experiences and applying to fellowships (posters, etc.) Research Experiences and Fellowships

33:07 Entering residency with a strong idea of what we want to pursue a fellowship in, what advice can you offer to help secure this fellowship? And on the contrary, if you have no idea what you want to do how do you recommend people narrow it down? 

46:00 How do we navigate the type of career setting we want to be in? 

50:15 What conferences do you recommend residents attend?

55:00 How do you recommend maintaining work/life balance and experiencing burnout?

1:00:50 Outro

Resources:
·        Book: Getting Things Done by David Allen

·        Book: Make It Stick: The Science of Successful Learning by Peter Brown

·        Book: Peak by Anders Ericsson

04 Mar 2022The Laboratory’s Role in Health and Equity 00:20:03

Timestamps:

00:00 Intro

01:23 Why is health equity important for laboratory medicine and pathology?

03:13 What are we learning about how as a laboratory we may better advocate for health equity? 

05:27 What’s the nuance there that we need to grapple with, not just more testing but better testing?

08:30 Are there examples of how we can do this better from other professions that we can learn from? 

09:59 Is that something that you feel with your previous experience as a hematopathologist has prepared you for or are these additional skills you’ve picked up along the way?

12:10 What are two or three ways that we are trying to navigate this for increasing health care equity?

14:36 What kind of feedback can a pathologist provide that helps them build a better test?

20:20 What does the future of health equity look like, what does that laboratory support of health equity look like in the coming years?

21:27 Outro

Resources:

The COVID pandemic: Testing and disparities:

 https://chs.asu.edu/diagnostics-commons/blog/covid-pandemic-testing-and-disparities 

To hear more on this topic from Dr. Morice, register for the 2022 Phlebotomy Conference: https://news.mayocliniclabs.com/edu-conferences/phlebotomy-2022-performance-public-health-people-in-a-post-covid-world/ 

06 May 2022Integrating Molecular Information Into Your Anatomic Pathology Practice00:15:51

Timestamps:

00:00 Intro

01:04 Why is molecular information important for you in your practice to integrate into anatomic pathology? 

06:22 How did you recognize that molecular information was really a critical competency for you to develop as an anatomic pathologist? 

09:51 Do you find yourself going to different sessions when you go to conferences, or are you specifically paying attention to ones that have a molecular thread through them?

11:23 How do you recommend that we all continue to embrace new opportunities in clinical practice? 

13:01 We are talking about how molecular has come down the pike and been something new that’s been added on to your practice. Is this importance of channels of communication, how has it changed in recent years?

14:45 Outro

18 Jun 2021Hereditary oncology: Molecular testing for solid tumors 00:21:03

Timestamps:

00:00 Intro

00:45 Why is it important to perform molecular testing on solid tumors?

02:47 What is the significance of this testing for the patients and physicians?

07:18 Can you share with us, what are some recent examples that have blown this door open about hereditary oncology?

10:28 Can you talk a little bit about the challenge on how do we get the rapid rise in molecular knowledge and testing? What is your perspective?

15:25 Can you elaborate a little bit on how you interact with your clinical colleagues on how to keep people up to date, or how to explore what’s the right thing to bring on to that test menu? 

18:11 What’s your secret to leveraging those relationships?

20:00 What does the future of molecular tumor testing look like?

21:48 Outro 

22 Jan 2021Cellular therapy: Responding to COVID-1900:16:32

Timestamps:

00:00 Intro

00:58 How is cellular therapy contributing to the COVID effort?

04:42 Can you give us a little bit of an introduction about what’s so important about the cell (mesenchymal stem cell) or where it comes from?

08:19 What sort of work are you and your lab doing for patient care?

11:14 Once you figure out a successful cellular therapy, is there then opportunity for that to get brought to scale for a given patient population, or does cellular therapy need to exist as a very individualized treatment?

13:48 For our listeners who might be students or other clinicians or laboratory medicine folks, how can they get involved in cellular therapy or how do you recommend those first steps to learn more about this field and how they might intersect with it?

15:50 Outro

Resources:

https://stemcellsjournals.onlinelibrary.wiley.com/doi/10.1002/sctm.20-0472 

https://www.medrxiv.org/content/10.1101/2020.10.15.20122523v2 

19 Apr 2024Exploring the Lab's Vital Role in Healthcare00:18:07

In this episode of “Lab Medicine Rounds,” host Justin Kreuter, M.D., speaks with Chancey Christenson, M.D., about the lab's important role in healthcare.
 
Timestamps:
0:00 Intro
01:00 Why is it important to highlight the extensive presence of the laboratory in current medical practice?
05:20 What’s the story of how you first came to appreciate the extensive role of the medical laboratory?
07:03 How do you and your team work together for efficient patient care?
10:15 Do you have any thoughts or advice for how to move through setbacks and creating that environment where people feel empowered to speak?
11:57 How do you see the role of the laboratory evolving in the coming years?
17:35 Closing

03 Sep 2021Rapid reference laboratory development00:14:29

Timestamps:
00:00 Intro

01:10 Why is reference laboratory testing important for physicians and laboratorians to understand?

02:00 No lab does all the testing in their own laboratory. Labs can’t really have a whole panel of laboratory tests; it just doesn’t make sense, right?

04:39 What have we learned in the last couple years about reference laboratories, how we can best support clinical practice?

06:10 Do you have an insight for how that communication goes? 

8:46 How might a hospital reach out and partner with their reference laboratory? 

11:06 What does the future of reference laboratories look like? What might be in store for us?

15:00 Outro

Register for Leveraging the Laboratory:
www.news.mayocliniclabs.com/2021levlab

01 Jul 2022Challenges of Saliva Testing 00:15:31

Timestamps:

0:00 Intro

00:53 Why is the medical field interested in saliva?

02:00 What sorts of information could be gleaned from saliva?

03:17 Are there certain limitations of what could come out of saliva testing?

04:56 Can you elaborate what you mean when you say “matrix?”

06:16 How do you approach navigating what could be interferences?

08:16 Would that be considered part of the matrix? Or is the matrix just the specimen itself?

9:29 Could you elaborate those preanalytic variables a clinician may have top of mind, or what might be in their sphere of control, influence, awareness?

11:41 What’s your advice to laboratory professionals about how we can detect when these kinds of things are going awry, or how do you keep your finger on the pulse of how your colleagues on the clinical side are using your tests?

13:34 What do you see as the future for saliva testing like?

14:54 Outro

Resources: 

https://www.aacc.org/cln/articles/2022/janfeb/saliva-in-the-spotlight 

https://news.mayocliniclabs.com/2022/04/07/darci-block-ph-d-discusses-saliva-testing-in-aaccs-clinical-laboratory-news/ 


17 Dec 2021The ultimate gift: Organ transplantation 00:18:02

Timestamps:

00:00 Intro

01:05 How did you first get interested in supporting organ transplantation? 

04:53 What are the organs that we can transplant?

06:00 When we are at the Department of Motor Vehicles, we can register as a donor and make our wishes known to our family, is that right?

07:03 If people are interesting in donating a kidney, for example, do they reach out to their local hospital and let them know they are interested in being a donor?

08:50 How does your work in the Histocompatability laboratory, how does it support transplantation? 

10:57 Can you give our audience kind of a flavor of how does this work to do this kind of dance to match donor and recipient and have a successful transplant? 

13:11 What’s on the horizon for HLA and histocompatibility in the next couple of years?

18:30 The ability for us to identify a patient, these patients who could not get a transplant are now able to get the transplant because of these improvements in the laboratory.

20:01 Outro

Resources: 

 

Successful pig to human transplant articles:


18 Aug 2023Coagulation Basics00:16:29

In this episode of “Lab Medicine Rounds,” guest host Ann Moyer, M.D., Ph.D., speaks with Justin Kreuter, M.D., transfusion medicine pathologist and assistant professor of pathology and laboratory medicine at Mayo Clinic, about common misunderstandings and practical ways to teach the basics of coagulation.
 

Timestamps:
0:00 Intro
00:48 Why is it important for physicians to understand the fundamentals of coagulation?
02:27 In your experience, what are a few of the common misunderstandings that people might have?
08:15 Do you have any thoughts on what we can do better to teach a complicated topic like coagulation?
13:57 Are there any sessions at the upcoming Bleeding and Thrombosing Diseases conference that you are looking forward to in particular?
15:31 Outro

02 Sep 2022Using Social Media in Your Practice00:18:20

Timestamps

0:00 Intro
01:10 Why is social media a tool that our lab medicine and pathology community should consider using?
04:01 How do you reassure or talk to a pathology resident or a medical laboratory technologist, who is just getting started on social media, when a patient reaches out with a question?
07:29 What is your advice about how to use your time wisely on social media?
09:57 How do you think about the social media landscape at this point, realizing things are dynamic and changing? How do you characterize and think about these different platforms?
12:10 How has your social media practice evolved over time? What has your journey been like and how has this affected you?
14:48 What skills do you think that you can walk away from this with, what skills have this been helping with for you?
16:44 What is next for you? What challenges do you want to throw out there for the experienced social media person?
17:42 Outro

16 Apr 2020COVID-19: What's Serology Got to Do with It?00:15:57

Time Stamps

 

00:00 Podcast Intro

 

00:50 Why is it important to have a serologic test for COVID-19 when there are already molecular PCR assays for diagnosis?

 

01:38 How are we going to b using the serologic test in clinical practice? 

 

03:02 When should and when shouldn’t we be ordering the serologic assay?

 

04:34 Can you elaborate on some of the limitations of this test?

 

06:05 Should we be listening to their local area is recommending related to COVID-19?

 

06:49 What are the challenges that you have to navigate with serologic testing for COVID-19?

 

09:32 This has really been a collaborative effort across the country to implement this test. Would you mind sharing what implementation of this serologic assay looked like? 

 

12:58 What are some lessons learned at this point that you think would be worth sharing to the lab professionals and students that listen to this podcast?

15 Jul 20223D Imaging Technology00:18:41

Timestamps:
0:00 Intro
00:46 Why is 3D imaging and printing important for patient care?
03:18 Can you help our audience understand when should we be using this? When is it not so good? 
09:38 How does that conversation go now differently? Now that somebody can hold this, how has that transformed the questions and the understanding that the patient has?
13:05 Can you help us get our arms around what is the value in the scan, what is the print value?
14:01 Technologies for scanning are improving and that’s resulting in better models for you to look at. Is printing of materials being used improving in such a way you can get the same textures?
15:22 How do you see this field really developing? 
17:55 Outro

03 May 2024Lab Excellence: Spotlight on Laboratory Professionals00:14:41

In this episode of “Lab Medicine Rounds,” host Justin Kreuter, M.D., interviews Eric Hsi, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic in Rochester, Minnesota, about the lab’s important role in healthcare.

Timestamps:
00:00 Intro
00:42 Importance of labs in current medical practice
02:41 Understanding & appreciating the role of lab medicine
05:30 Working as a team to affect patient care
08:14 What advice do you have for upcoming lab professionals to cultivate their leadership skills?
12:43 Where do you see the future of laboratory medicine?



11 Sep 2020Laboratory Detection of Opioids00:13:07

Time Stamps

00:00 Podcast Intro

00:40 Why is it important for a laboratory to detect or quantify opioids?

02:00 What are the challenges you have had to navigate in the laboratory specific to opioids?

04:47 Is it like a pregnancy test or is it important to quantify as well?

05:19 Can you help us understand how you collaborate with other health care professionals? 

07:07 In terms of new or illicit street drugs, are you having to constantly design new tests to detect these things?

07:53 Can you elaborate a little about that collaboration with law enforcement?

09:07 Are you also periodically going to testify in court on cases?

09:35 What do you think the future of opioid testing looks like?

12:25 Outro 

19 Nov 2021Pathologist's role in medical education00:26:42

Timestamps:

00:00 Intro

00:48 What’s your origin story? How did you get interested in medical school education?

06:18 What are we learning about better ways to educate? 

13:42 How can faculty make it a safe environment? How can we get students to give it a try?

16:25 How do you bring about and navigate curricular change?

20:15 Was there something that you did that prepared you for this role? Is there some advice for people who are interested in taking a leadership role in education at their institution? 

24:04 Could you share what you think the future of medical education will look like?

28:33 Outro

06 May 2020Understanding COVID-Associated Coagulopathy00:18:15

Time Stamps

 

00:00 Podcast Intro

 

00:40 What is COVID-associated coagulopathy and why is it important to recognize this?

 

02:45 How is this coagulopathy similar to or different from other coagulopathies that we commonly see in clinical practice?

 

04:30 Is there recommended testing for COVID-associated coagulopathy?

 

06:30 Can you explain what the soluble fibrin monomer test is?

 

08:09 How is COVID-associated coagulopathy managed in terms on prophylactic anticoagulation, therapeutic anticoagulation, and prophylactic transfusion?

 

14:23 What are a few lessons that you have learned during this pandemic so far?

 

Resources:

1.       F.A. Klok, M.J.H.A. Kruip, N.J.M. van der Meer, et al., Incidence of thrombotic complications in critically ill ICU patients with COVID-19,Thrombosis Research (2020), https://doi.org/10.1016/j.thromres.2020.04.013  

 

2.       doi:10.1111/JTH.14810 

06 Oct 2023Cardiac Troponins and Checkpoint Inhibitors00:22:16

In this episode of “Lab Medicine Rounds,” host Justin Kreuter, M.D., speaks with Allan Jaffe, M.D., a consultant in the Department of Laboratory Medicine and Pathology at Mayo Clinic, about cardiac troponins and checkpoint inhibitors. Dr. Jaffe is also the Wayne and Kathryn Preisel Professor of Cardiovascular Disease Research, professor of laboratory medicine and pathology, and professor of medicine in the Mayo Clinic College of Medicine and Science.

 
Discussion includes:

00:47 Introductory background on checkpoint inhibitors and cardiac troponins.

15:12  Challenges with recognizing immune checkpoint inhibitor-associated myocarditis.
19:28  Key takeaways for how laboratory professionals can support these patients.

19:28 Considerations of questions that are top of mind when tackling these issues.

08 Nov 2024Attending Medical Conferences & AABB Debrief00:20:30

In this episode of “Lab Medicine Rounds,” Justin Kreuter, M.D., interviews John Sherbeck, M.D., Laboratory Medical Director of Trinity Health IHA Medical Group, about how to plan your time at medical conferences. He also briefly discusses this year’s takeaways from AABB’s national conference.

Timestamps:
0:00 Intro
00:45 Why are medical conferences important to attend?
03:10 Engaging in debate
05:11 Prepping your team to present at a national conference
06:40 Take aways from the AABB annual meeting?
09:57 When you attend a conference, how do you go about planning out your time?
12:57 How do you approach networking?
15:05 What is your current practice for approaching vendors?
17:18 How do you capture your conference learning?
19:50 Outro

16 Feb 2024Charting the Course: The Journey to Becoming a Physician-Scientist00:24:04

In this episode of “Lab Medicine Rounds,” host Justin Kreuter, M.D., speaks with Alfredo Quinones-Hinojosa, M.D., a neurosurgeon and scientist at Mayo Clinic. From humble beginnings as a migrant worker, his story is one of resilience, determination, and a relentless pursuit of knowledge.

Timestamps:
0:00 Introduction
1:54 Importance for physicians to play a role in science
5:28 Setting yourself up for success
9:48 Inquisitive mind
14:00 Mentoring
22:00 Looking ahead
23:55 Outro

07 Jan 2022Responding With Grace While Under Pressure00:17:45

Timestamps:

00:00 Intro

02:00 Why is it important to respond with grace while we’re under pressure?

03:36 How do you think you develop this ability to project poise when in stressful situations?

05:33 Was there a mentor, situation, or experience where it gave you pause and made you think, “Wow, that’s somebody that really showed grace under pressure and leadership abilities.” Is there anybody in your life who comes to mind? 

07:15 Did you find yourself having some of these mental conversations? How did that go for you?  

08:36 Are those two questions (1. Does this make sense? 2. What could possibly go wrong?) that you’ve been using for a number of years, or is this something that has been more recent for you?

10:57 I’m curious about how do you recognize in your own self, how do you notice when you’re getting challenged and keep it on the rails?

14:28 What’s your feedback to the young professionals in our community to collect themselves in their thoughts?

15:45 How do you continue to grow in your professionalism in your ability to be a more effective leader more broadly?

16:29 What does that well mean to you? What does that look like?

19:54 Outro


Resources:

https://domorestories.com/profile.php?handle=jane-hata 

08 Jan 2021COVID-19 vaccinations and laboratory testing00:12:21

00:00 Intro

00:45 Can you let our listeners know what we know about the vaccines at this point (December 2020)?

02:00 With using the mRNA approach, do these vaccines have similar performance characteristics?

03:00 What does this mean for people after they get vaccinated? Hearing this high numbers of efficacy that is protecting me from the virus, what does this mean for how I should be behaving after I get vaccinated?

04:25 What are your thoughts on if there should be post-vaccination serology testing?

07:10 From your standpoint in the laboratory, has the laboratory developed all the tests that are needed? With the vaccines coming out, is laboratory medicine’s job done regarding COVID-19? Or do the folks in research and development still have some things they need to get done in lab medicine?

10:15 Is the fact that we have a couple of variations out there a testament that this was testing that needed to be brought up in the moment, which is why there are a couple of different strategies, and maybe over time we will see a convergence towards one over the other? Or, is there a reason to continue keeping these assays up because it really needs to be a battery in order to be accurate?

11:35 Outro

27 Aug 2021Perspectives from a visiting medical student: Path to success00:19:40

Timestamps:

00:00 Intro

01:15 Why are external rotations in pathology important from the student perspective?

03:51 Do you get to understand the particulars of a program or maybe what kind of questions you might be asking when you later interview because you do a rotation? 

05:03 What is unique from an international perspective? 

07:53 Can you compare and contrast the in-person pathology elective, with some of the virtual resources that are available at this point and time?

11:02 Are there any additional resources that you want to point out that are available now in 2021?

12:34 Can you kind of dive in and provide advice for people that are following in your shoes who might be doing later electives this year or in the near future who are looking at applying to pathology in the next cycle?  

13:41 Can you dive in and elaborate on what are some of the helpful things when students get onsite for one of these rotations?

17:26 Can you help us understand how you go about cultivating those relationships? 

19:36 Are there any kind of parting words of wisdom that you want to leave with future applicants that are checking out this podcast episode?

20:47 Outro 

 

 

 

07 Feb 2020Proficiency Testing Referral: What You Don't Know Can Hurt You (a Lot)00:29:50

Time Stamps

00:00 Podcast Intro 

01:25 What is proficiency testing?

04:10 Proficiency testing insures my lab is actually getting the accurate results? 

05:26 What is proficiency testing referral and why is it important for laboratory medical directors, administrators, supervisors and staff to be aware of PT referral rules? 

07:54 Why would laboratories refer proficiency testing to another external lab?

12:05 What’s happening at working to reduce this risk for me? Taking Essential Steps for Testing (TEST) Act of 2012

15:23 These are “near-miss” events and definitely something to learn from, discussing how the holes lined up, what occurred, and now here’s your opportunity to patch that hole?

17:04 What new trends in laboratory medicine have increased the risk of sanctions for proficiency testing referral?

19:55 What are the most effective strategies to prevent proficiency testing referral?


22:26 Are there good resources for this education? Or is every lab on their own to create content?


23:17 In your experience, being on committees and doing inspections at hospitals, what has surprised you most about this issue of PT and referral?


26:17 How do you approach training pathology residents and fellows in understanding proficiency testing, what they are responsible for, how do they trouble shoot a proficiency failure? I imagine it’s difficult to introduce that topic.


28:10 Outro

 

Additional Resources:

CMS Brochure on PT Referrals @ cms.gov

03 Mar 2023No Excuses00:15:16

In this episode of “Lab Medicine Rounds,” Justin Kreuter, M.D., speaks with Beshoi Nashed, a visiting medical student from the Medical University of the Americas in Saint Kitts and Nevis, about his personal perspective on life that has helped him succeed where many others are challenged.
 

Timestamps:
0:00 Intro
01:08 Where were you first introduced to this no excuses philosophy perspective, and what is it?
03:09 What’s the perspective they had that they really imparted on you, what did it look like? 
06:44 What do you think is important for our listeners to understand about, what is it that allows you to be successful with this no excuses approach?
10:22 How has your practice changed, if at all, over that time?
12:35 Where do you recommend our listeners get their own start?
14:22 Outro

01 Dec 2023Nurturing Our Laboratories00:15:40

In this episode of “Lab Medicine Rounds,” host Justin Kreuter, M.D., speaks with Alex Klobassa, assistant supervisor for transfusion medicine in the Department of Laboratory Medicine and Pathology at Mayo Clinic, to discuss nurturing our laboratories. 

03:38 Challenges to nurturing laboratory teams.

02:39 Takeaways from nurturing laboratory teams.

07:42 Creating programs to support laboratory staff.

14:21 Ways to improve our laboratories.

04 Nov 2022The ABCs of CBD00:17:32

Timestamps:
0:00
Introduction
1:18 What is the difference between marijuana, hemp, THC, and CBD?
2:58 So, is CBD legal in the United States?
4:08 What are the common products you can find CBD in?
4:25 How can CBD impact our health? Especially since it is not regulated.
5:28 You run our drugs of abuse and forensics lab, is this having any effect on the testing you do there?
10:45 For our laboratory medicine colleagues, what's important for them to understand about CBD and marijuana drug testing?
13:55 What about different industries? How does it affect athletes in recovery for example?
16:50 Are there any other takeaways you want the audience to appreciate from this?
18:31 Outro

04 Jun 2021Frozen sections: Value & challenges 00:25:16

Timestamps:

00:00 Intro

01:11 What are frozen sections, and why are they an important part of patient care?

04:50 What are some of the challenges of actually performing a frozen section diagnosis?

07:03 How has frozen section changed in recent years, or over the course of practice? Has it been practiced similarly over the years, and are there differences in frozen section practice in different hospitals?

14:37 Given this uptick in the complexity of cases, how do you mentor people who are trying to find their way, i.e., the students and trainees?

19:14 As a practicing Pathologist, where do you solicit your feedback from, and maybe an example of how you use that feedback to get better? 

24:32 Looking at the future in pathology and surgical pathology, there’s so much interest in artificial intelligence and informatics; is that thought to play a role in the future of the frozen section practice?

27:51 Outro 

07 Mar 2025The Future of Basic Science in Medical Curriculum00:19:50

On this episode of “Lab Medicine Rounds,” Justin Kreuter, M.D., speaks with senior associate dean of academic affairs for Mayo Clinic Alix School of Medicine, Joseph Maleszewski, M.D., on the future of basic sciences in medical education.

Discussion includes:

·       Challenges of basic science in medical education.

·       Differing perspectives about basic science in medical education.

·       Ideas of exploration for the future.

06 Dec 2019The Flu: Nothing to Sneeze About!00:30:15

Time Stamps

00:00 Podcast Intro

01:00 How is influenza different from other respiratory infections, such as the common cold?

02:02 Why is influenza such a big deal? Many people think about influenza for different reasons, but how can we hit this home for the everyday person?

04:43 Can we unpack the idea of getting vaccinations, specifically getting vaccinations every year?

06:36 Can you address some of the common misperceptions when it comes to getting the flu vaccine? 

11:02 Who should see their doctor when they exhibit flu-like symptoms?

12:36 How is the influenza test changing?

14:45 The idea of point-of-care testing that bridges the patient/clinical practice and the laboratory supporting that practice caring for that patient. Can you discuss what some of the logistics and challenges are that come in to point-of-care testing?

16:02 What does it mean in regards to treatment of influenza with having a more sensitive test that is rapidly available?

 17:55 How are we spreading this knowledge to all of our physicians so they can understand how to make the decision of who needs be treated and why?

19:23 Are there any questions or feedback that either of you have gotten from other physicians or nurses on this topic that surprised you?

21:25 Is there a future state on the horizon where you think we may not need to be getting the influenza shot every year?

23:57 This podcast is really centered on building bridges between the clinical world and the lab world. Would you mind sharing a story that highlights where this collaboration has really helped the patient? 

26:47 I’m curious, for the trainees in your program, how are they trained/mentored on crossing the boundaries between the clinical and laboratory?

28:59 Is there anything you would like to add that we haven’t talked about so far?

Additional resources:
https://www.cdc.gov/flu/index.htm

18 Oct 2019My Mouth Is Not Watering: The Perplexing World of Salivary Gland Pathology00:14:14

Time Stamps

00:00 Podcast Intro

00:37 Introduction of Joaquin Garcia, Vice Chair of Laboratories in the Division of Anatomic Pathology and Medical Director of the Histology Laboratory at Mayo Clinic.

00:57 Can you give us a little background as to how you came in to this world of anatomic pathology and also where did this interest of salivary gland tumors come from?

02:09 What are the things that come to your attention when people are asking about salivary gland tumors?

03:13 When you talk about getting a small biopsy, are we talking about getting a punch biopsy for skin or are we talking about a fine needle aspirate where your just getting cytology? 

04:11 Can you get in to a little bit on where this challenge comes from, whether something is benign, malignant, kind of predicting that behavior?

05:46 How do you train up pathologists to make these calls and recognize malignant from benign?

07:04 Can you elaborate on some of the additional testing you’re talking about (immunohistochemical staining and liquid kind of samples)?

08:48 So, in a more targeted way you are able to make a diagnosis. Is that also true for how we are treating these cancers? Are we able to do targeted therapy based on the pathology that we are getting?

09:54 You’ve just recently completed a book “The Atlas of Salivary Gland Pathology.” What surprised you most about what it took to put together this atlas?

10:35 Is it true that head and neck pathology is the most challenging sub-specialty within all of anatomic pathology?

11:02 What sort of things should be features that are concerning, so that when you hear this in the history you really want to do a thorough exam of the patients mouth, face, and neck features?  

13:35 Outro

Resources: 
Atlas of Salivary Gland Pathology, 2019, Springer Publishing (JJ Garcia)

18 Nov 2022Lifelong Learning00:22:10

Timestamps:
0:00 Introduction

0:40 Non-traditional education for pathologists

11:17 Getting involved

13:41 Self-learning

16:19 Becoming an expert

18:46 Other interests in practice or life

22:05 Importance of completing projects

23:59 Outro 

21 Aug 2020Addressing Diversity & Inclusion in Pathology00:17:21

Timestamps
00:00 Podcast Intro

00:45 Why is it important for laboratory medicine and pathology to be deliberate about diversity and inclusion? 

03:11 How do you recommend we transform the question “will they fit?” or “do I fit?” so that it invites diversity?

05:33 So, it’s not so much of transforming the question but putting it ahead of the interview and thinking about what you are trying to recruit for? 

06:22 What information have we recently learned about diversity and inclusion in the newer findings? 

10:35 How is it easier and/or harder to move the needle on diversity and inclusion in the laboratory?

13:35 In 5 years, where will Laboratory Medicine and Pathology be with respect to diversity and inclusion?

16:05 Outro 

14 Feb 2020The Littlest Things in Life - The Burning Sensations of Love: Let's Talk STDs (Part 1)00:28:17

Time Stamps

00:00 Podcast Intro 

01:08 Introduction of Stacey Rizza, M.D.

01:50 What is the natural course of HIV if left untreated, and what effects would it have on the body? 

03:41 So given those numbers then, who should be tested for HIV?

04:32 How should HIV be treated?

05:29 Do people living with HIV then when they are on therapy need any additional, special kind of care?

06:44 So if someone who’s living with HIV is actually receiving the treatment and doing everything they should be doing, will the disease naturally shorten their life?

07:28 Now given that we’re talking about sexually transmitted diseases, is it safe for a person with HIV to have unprotected sex?

09:57 Given those conversations, is that usually how it goes when people ask how HIV can be prevented, or is there more to it?

11:59 Another thing that’s coming out every month or so we hear about the new technological advances towards a cure for HIV, so how are we doing on that? Is HIV curable? 

13:35  So one of the things that comes up fairly frequently every few years is the Delta 32 mutation, which is a mutation that it’s my understanding intrinsically confers some level of resistance against HIV infection?

15:50 HIV is a very large global burden and as a result there has been a lot of outreach around the world from many different organizations. Here in American in 2003, President George W. Bush signed PEPFAR, The President's Emergency Plan For AIDS Relief.  What are your thoughts on how well it’s been doing?

17:48 To shift gears here, we’re going to shift from viruses to bacteria. One in particular with a tumultuous history is syphilis. What is syphilis and what effects does it have on the body?

21:08 So that being said, with it having an asymptomatic period where it doesn’t look like you have it at all, who should be tested for syphilis?  

21:57 How is syphilis treated?

22:36 So if someone is treated for syphilis, can it reoccur? 

23:30 What about prevention? Can syphilitic infection be prevented?

24:14 According to the CDC congenital syphilis cases has risen consecutively over the last five years, is there anything we should be doing for increased surveillance?

25:42 What does congenital syphilis look like?

26:23 Is there a vaccine for syphilis?

27:39 Outro

01 Jul 2020Our opportunity: Helping patients understand laboratory testing00:34:40

Time Stamps

00:00 Podcast Intro

01:05 Why is it important to explain the laboratory to patients? How important it is to have open/honest communication with patients?

07:05 With your experience in talking with children and their families is your focus on the child and the parents picks up on your efforts? Or are you addressing the child separately from their parents?  

11:10 What tips would you have for pathologists as they approach certain situations (approaching the bedside, engaging with patients, answering questions regarding lab tests or biopsies, etc.)

16:26 What are your tips for clinicians on explaining the laboratory to patients?

 20:22 For our student listeners, what has been your most impactful lesson learned?

23:17 You started to create a video to show kids and their families what is happening in the lab behind the scenes, where does their samples go, etc. How are you approaching this? 

27:00 Do you envision that material will be geared towards grades K-5 and then different content for teenagers? How differentiated does the education get?

06 Sep 2019Tick Talk00:12:55

Time Stamps

00:00 Podcast Intro

00:39 Introduction of Bobbi Pritt, M.D. 

00:56 What are ticks?

1:42 What diseases can be transmitted by ticks?

2:03 Background on ticks

2:46 What should we be suspicious of for the diseases ticks carry? (Location)

4:03 When should I be really concerned about tick borne disease? (Timing)

4:56 Laboratory Testing 

6:15 Links to Resources (Algorithm & CDC website):

 https://www.mayocliniclabs.com/it-mmfiles/Acute_Tick-Borne_Disease_Testing_Algorithm.pdf

https://www.cdc.gov/ticks/index.html

6:44 When should I not test?

8:30 How can we protect ourselves from these tick borne diseases?

9:23 ABC’s of Tick Bite Prevention: https://news.mayocliniclabs.com/ticks 

11:03 Key Takeaways 

12:10 Outro

07 Jul 2023Discovering Online Pathology Resources00:20:13

In this episode of “Lab Medicine Rounds,” Justin Kreuter, M.D., sits down with Clarissa Jordan, M.D., chief resident in anatomic and clinical pathology for the Department of Laboratory Medicine and Pathology at Mayo Clinic, to discuss online pathology resources. 

Resources:

  1. AACC  Learning Lab: https://www.aacc.org/education/learning-lab 
  2. Kurt’s Notes: https://schaberg.faculty.ucdavis.edu/
  3. Surgical Pathology Reimagined (textbooks): https://www.acemypath.com/books
  4. https://www.pathcejmd.com


19 Aug 2022Patient-Scientists: A Valuable Perspective in Medical Research 00:13:17

Timestamps:

0:00 Intro

01:01 What is a patient-scientist? 

01:36 What’s the perspective of value they can bring to the table?

03:57 What has surprised you the most about this experience of being a patient-scientist?

08:05 Since you have shared this, what has been your experience interacting with the research community?

08:57 What are your reflections about how the medical community should understand about developing these relationships, seeking out or welcoming patient scientists in their research, interest or questions?

10:46 What’s been your own experience when you go to patient or research conferences, what is your experience like in those situations given you’re on both sides? 

12:34 Outro

Resources:

TEDx: Researching Your Own Disease

Society of Patient Scientists

24 Jan 2025Embracing Diversity, Equity, and Inclusion in Every Identity00:22:03

In this month's episode of Lab Medicine Rounds, Justin Kreuter, M.D., speaks with Monica Ibarra about the essential role of diversity, equity, and inclusion in healthcare and beyond. 

Timestamps:
0:00 Introduction
0:43 Why conversations about diversity are important
3:56 Common challenges that arise during discussions
6:11 Approaching conversations in different environments
11:17 Leaders navigating challenging DEI conversations
20:00 Diversity reflection questions to ask yourself

06 Sep 2019One Small Bite, Deadly for Mankind00:22:07

Time Stamps

00:00 Podcast Intro

00:48 Introduction of Elitza Theel, Ph.D.  

1:03 What is the deadliest creature in the world?

2:30 How many types of mosquitoes are there?

3:50 Why do mosquitoes bite us?

4:54 What types of infections do they cause?

6:33 What advice do you give students and learners regarding this topic? 

7:37 How does somebody make the diagnosis?

7:54 How can you use lab testing to keep on the right track?

10:49 What are some of the frequent calls received as a Laboratory Director?

13:26  Are these mosquito borne diseases treatable?

13:53 Where do you figure out the species?

14:59 What about treatment for mosquito borne viruses?

15:17 What about vaccines for mosquito born viruses?

16:27 What do you see as the future trends in the world of mosquito borne disease?

18:13 What are your recommendations for protecting against mosquitoes? 

19:33 Fun fact on how spreading infections may occur 

21:31 Outro

Additional Resources:

https://www.cdc.gov/ncezid/dvbd/index.html 

03 Dec 2021Valley fever testing: Right test, right time, right patient 00:20:11

Timestamps:

00:00 Intro

01:24 Why does clinical context matter for what test clinicians order?

08:41 What determines what kind of test to order?

13:07 How does the communication happen between the lab and the clinician? How should it happen to provide best care for the patient?

18:21 What do you think about for the future of ordering laboratory tests? 

21:59 Outro

02 Aug 2024Reflections on Residency00:18:09

In this month’s episode of “Lab Medicine Rounds,” Justin Kreuter, M.D., interviews Isabella Holmes, D.O., a PGY-3 resident and assistant co-chief pathology resident at the University of Michigan, to discuss her reflections on residency. 

Timestamps:
0:00 Intro

01:20 Reflections on past year

02:45 Being comfortable as a resident

05:00 Taking on leadership roles

07:51 Identifying what to focus on

11:06 Becoming better mentors

13:01 Being respectfully direct

14:17 New academic year

16:06 Balancing work and personal well-being

17:26 Outro

19 May 2023Leading through Uncertanity00:16:15

In this episode of “Lab Medicine Rounds,” Justin Kreuter, M.D., sits down with Matthew Binnicker, Ph.D., Director of Clinical Virology and Vice Chair of Practice in the Department of Laboratory Medicine and Pathology a Mayo Clinic, to talk about working and leading through uncertainty.

Timestamps:
0:00 Intro
01:22 Why is working with uncertainty an important skill for us to cultivate?
03:13 What are ways to keep grounded when navigating uncertainty?
06:17 When you are not in a crisis moment, when it’s not an ambiguous time, how do you behave in a way that further cultivates this idea that you are a leader?
08:22 How could we help our colleagues who are struggling with uncertainty?
10:12 How can we help people with a fixed mindset as opposed to a growth mindset move from seeing negative feedback as uncomfortable, how can we help them see the growth and opportunity in front of them?
12:09 I’m curious if you could share with our listeners a story of how uncertainty has surprised you most?
15:35 Outro

05 Mar 2021Transfusion support of ECMO patients00:17:43

Timestamps:

00:00 Intro

01:07 Why is transfusion support an especially important component of patient care for patients that are on ECMO support?

03:24 Are there some principles that we can think about that will help us better understand transfusion decisions in these patients?

05:52 Can you take us through some specific situations that might help our listeners get our hands around (DO2 and VO2) from a practical standpoint? 

10:31 How can laboratory professionals add value to the clinical care of these patients?

12:35 How can we improve that interaction (between the clinical side and the laboratory side)? 

16:41 What are the different devices we need to keep in mind?

17:11 Outro

02 Apr 2021Cultivating quality in the clinical practice 00:24:19

Timestamps:

00:00 Intro

01:29 Why is it really important for leaders in our practice to really understand quality for clinical practice?

03:13 What are the latest developments in your area of clinical laboratory medicine?

06:01 In recent years, what have we learned about quality and how we do quality in the hospital?

11:19 How do we actually implement this in clinical practice for success, for sustainability? You talked about putting together an interdisciplinary team. What’s the secret sauce for putting that together?  

15:36 You talk about recognition for these project successes. How do we do that when maybe the project is a failure, but still keep that motivation high in our community, make sure it’s normalized as sometimes it doesn’t work out, but not something we don’t talk about anymore?

18:12 What have you kind of learned from your experiences for what are ways to make projects successful and sustainable?

20:28 Can we kind of closeout with thoughts on where the future of quality improvement in medicine is headed? What are your thoughts on that?

 23:35 Outro

05 Feb 2021Let's talk cellular therapy00:16:05

00:00 Intro

01:15 From your perspective, why is cellular therapy an important topic for our listeners?

02:55 What is your origin story into this world of cellular therapy? 

06:20 Working in such a fast-paced area, what has been a unique challenge you have had to navigate and how have you done that?  

08:05 Keeping up with the literature can be a challenge, and once you are out of training you don’t have those deadlines of “have you read your recent articles for the month.” How have you approached keeping up with the literature?

11:53 There is so much potential with cellular therapy. What is one direction you see this field moving towards over the next 5 years? 

15:34 Outro

20 Jan 2023Workforce Stability and Strategies for Retention 00:21:41

Timestamps

0:00 Intro

00:45 Why is workforce stability such an important topic for health care right now?

04:25 What are a couple of the current challenges? Maybe a few with hiring, and then a few with retaining some of these quality employees.

07:17 What are your thoughts about how do you keep your fingers on the pulse of the current needs and interest of the workforce? What’s the way to be a constantly evolving organization?

09:04 Is this something that is a regular topic of discussion with management meeting about what we are hearing from our employees, or is this something that is more informal that you’re meeting with leadership for your group, reflecting on what you’re hearing from your employees and meetings? What does that look like?

09:23 How does the laboratory and histocompatibility support organ transplantation? What kind of work happens behind the scene that enables this transplant to be as successful as possible?

11:32 How do you handle and manage that in a positive way, when employees are making these great suggestions, but like you said you just can’t just on a dime change the work hours in many cases?

14:27 What are some of your top recruitment strategies?

16:40 How do you assess which strategies are more effective?

18:38 Can you speak to some potential educational opportunities where listeners can learn more about this?

20:39 Outro

03 Feb 2023Challenges of Patient Education: Helping Patients Understand Relevant Medical Information00:23:03

0:00 Intro

01:04 What is your origin story? How did you come to work in this unique health setting of educating patients?

05:19 What are some of the common ways that you see healthcare really fail to successfully educate patients?

09:59 How do you navigate the complexity of what you’re talking about? 

16:12 How do you navigate those situations where the patient doesn’t seem to be understanding the information?

18:05 What does the future of patient education look like to you?

22:12 Outro

06 Dec 2024Global Surgery Hackathon: Lessons in Healthcare Systems00:35:47

In this episode of “Lab Medicine Rounds,” Justin Kreuter, M.D., speaks with medical students on the importance of understanding healthcare systems, their experiences from a global surgery hackathon, and how maintaining curiosity and continuous learning can enhance their medical practice.

Timestamps:
0:00 Introductions
0:49 Importance of Understanding Healthcare Systems
1:33 Fundamentals of Healthcare Systems
3:03 Complexity of Healthcare Systems
5:13 Selective vs Curriculum
6:08 Systems and Inequalities
7:18 Billing and Economics in Healthcare
8:17 Balancing Medical Training and System Knowledge
9:01 Curiosity and Continuous Learning
10:02 Learning Opportunities
13:02 Slowing Down in Critical Phases
16:41 Revising Healthcare Systems
18:02 Capturing Learning
22:03 Maintaining Curiosity
24:01 Advice for Developing Skills in Healthcare Systems

17 Nov 2023Pre-analytical Variables for Coagulation Testing00:17:15

In this episode of “Lab Medicine Rounds,” host Justin Kreuter, M.D., speaks with Jansen Seheult, M.B., B.Ch., B.A.O., M.D., assistant professor of laboratory medicine and pathology in the Division of Hematopathology, to discuss heterophile antibodies and HIL, which are considered by some to be analytical errors and by others to reflect patient-related pre-analytical variables.

Timestamps:
00:00 Introduction
00:40 Role of pre-analytical variables for coagulation testing
03:25 Common pre-analytical variables to be aware of
07:49 Medical community collaboration to mitigate patient-related issues
11:51  Share about an intervention that was tried and how that worked out
14:10 Future of coagulation testing
16:34 Outro

05 May 2023The Modern Parasitology Lab00:14:36

In this episode of “Lab Medicine Rounds,” Justin Kreuter, M.D., sits down with Bobbi Pritt, M.D., professor and interim chair for the Department of Laboratory Medicine and Pathology at Mayo Clinic in Rochester, Minnesota, to discuss the modern parasitology laboratory. 

Parasitology
0:00 Intro
01:03 Why did you decide to pursue parasitology?
02:19 What does the modern-day parasitology lab look like?
03:02 How are conventional and molecular techniques integrated to support the clinical practice?
05:04 Is this something that is easy to train up into using and integrating, or has this been an easy lift to get people used to working in this way?
06:45 Can you elaborate a little bit about the molecular aspects of how that might be integrated? Is this also a newer aspect for parasitology? 
08:57 How has this impacted your training for clinical fellows if maybe some things might be controversial right now? How do you prepare them to navigate the future ahead?
10:23 Have you heard feedback from ordering providers about the ability to have the syndromic panel and then the laboratory can chase it, has that been positively received? Are there challenges that come up with that style of ordering?
12:04 I’m curious if you can elaborate and share, what are a couple of the hot topics in the field for parasitology in 2023?
14:10 Outro

16 Dec 2022The Gift of Organ Donation 00:17:13

Timestamps:

0:00 Intro

01:54 How did you get started in the field of histocompatibility?

03:44 Was that a mentor that helped you find this new role and pathway, or was there a particular patient that you took care of that opened your eyes to these other possibilities in lab medicine?

05:28 What are a few things that you think healthcare professionals in general should understand about organ transplantation?

07:51 Maybe for you, as someone who was practicing first in orthopedic surgery, and then making this transition to systems thinking, what has that been like and how do you navigate that now?

09:23 How does the laboratory and histocompatibility support organ transplantation? What kind of work happens behind the scene that enables this transplant to be as successful as possible?

11:53 Is the laboratory involved with the care of the transplant patient beyond the acute transplant? What does that look like?

13:09 What do you predict is on the horizon for histocompatibility?

14:50 How could somebody support organ transplantation?

16:47 Outro

01 May 2020Convalescent Plasma: Why, How, and Lessons Learned00:23:30

Time Stamps

 

00:00 Podcast Intro

 

00:39 What is they ‘why’ behind starting up a convalescent plasma program?

 

04:00 If physicians are taking care of a patient and wanting to get this product how do they go about it?  

 

11:23 With the Expanded Access Protocol and Emergency IND, how many products does that get for the given patient?

 

13:00 Where should we direct people who are interested in being a donor?

 

14:51 Can you give us an idea on who would be eligible to donate convalescent plasma?

 

17:16 What are some lessons learned from your perspective as you have navigated through COVID-19 and the dynamic situation? 

 

Resources:


06 Jan 2023What Every Pathologist Needs to Know About the Legal System00:19:23

Timestamps:

0:00 Introduction

0:46 Why is it important for pathologists to know a thing or two about the legal system?

3:49 Quality practices are something we are all involved in. Can you unpack those a little bit so listeners can think about how they’re engaging in that?

5:05 High probability a physician or pathologist will eventually be involved in a legal proceeding. Tips for if/when that happens to you.

7:05 Importance of SOPs and Quality Plans

9:19 What does malpractice entail?

14:11 What do you recommend for people who want to take more of an active or deliberate role in keeping up with legal practices? 

20:32 International Surgical Pathology Symposium 2023 in London

21:18 Outro

02 Dec 2022Understanding Multiple Myeloma Testing00:17:20

Timestamps:

0:00 Introduction

0:37 Why is it important to update multiple myeloma testing?

1:51 Lab testing driving treatment that is being done

3:30 Explanation about multiple myeloma, how testing started, and how it has evolved

6:02 Needing more sensitivity to detect it

7:47 Driving treatment decisions

9:02 What does this look like in practice?

10:57 Minimal residual disease

12:41 Outside of the box thinking, how has this impacted your practice today?

17:41 Outro

17 May 2024Breathing Easier: Immunotherapies for Asthma and Allergy00:18:56

In this episode of “Lab Medicine Rounds,” host Justin Kreuter, M.D., interviews Douglas McMahon, M.D., from the Allergy and Asthma Center of Minnesota, to discuss how the lab supports asthma and allergy medical practice. 

02 Feb 2024Recruiting for Careers in Laboratory Medicine00:18:05

In this episode of “Lab Medicine Rounds,” host Justin Kreuter, M.D., speaks with placement coordinator Jamie Herget to discuss recruitment initiatives within the laboratory profession.

Timestamps:
0:00 Introduction
0:59 Importance of recruitment
2:57 What roles are being recruited?
5:31 Effective strategies for recruitment
9:28 Ineffective strategies for recruitment
15:01 Trends & Collaborations

Resources:
www.jobs.mayoclinic.org
Clinical Laboratory Technologist/Scientist - CLT/CLS/MLS at Mayo Clinic 

15 Mar 2024The Bullet Catch and Other Deadly Illusions!00:17:47

In this episode of “Lab Medicine Rounds,” host Justin Kreuter, M.D., speaks with Reade Quinton, M.D., assistant professor of laboratory medicine and pathology, to discuss a popular topic at this year’s 9th Annual Forensic Science Symposium, the bullet catch and other deadly illusions. 
 
Timestamps:
0:00 Introduction

0:45 Forensic Science Symposium discussion
3:30 Historical conference topics
5:50 Story of the bullet catch illusion 
10:00 Approach to storytelling
12:45 Developing presentation skills
16:30 Outro

01 Sep 2023How to Create Strong Professional Presentations00:20:47

In this episode of “Lab Medicine Rounds,” guest host Ann Moyer, M.D., Ph.D., speaks with Justin Kreuter, M.D., transfusion medicine pathologist and assistant professor of laboratory medicine and pathology at Mayo Clinic, about the importance of creating and practicing professional presentations.

 

Discussion Topics:

00:00 Introduction
01:03 Importance of practicing your presentation.

03:13 Common missteps in professional presentations.

07:52 Tips for putting together a strong presentation.

13:32 Tips for learners when presenting to experts in the field.

Resources:
https://pubmed.ncbi.nlm.nih.gov/15980086/

19 Jul 2024Advice to Trainees00:24:51

In this month’s episode of Lab Medicine Rounds, Justin Kreuter, M.D., interviews Nidhi Kataria, M.B.B.S., and Thane Kubik, M.D., M.S., for a deep dive into optimizing the residency experience. 

07 Feb 2025Building Your Ideal Rank List00:18:14

On this episode of “Lab Medicine Rounds,” Just Kreuter, M.D., chats with Jennifer Boland Froemming, M.D., about creating the perfect rank list for training programs. Dr. Boland Froemming shares her insights and tips to help you make informed decisions.

Discussion Includes:

00:36 How rank lists work.

03:45 What to consider when making a rank list.

06:20 Recommendations for individuals applying to training programs.

20 Aug 2021COVID-19 laboratory innovations: Sequencing and diagnostics 00:14:32

Timestamps:

00:00 Intro

00:44 With this latest outbreak of the Delta variant with COVID-19, are laboratorians still working on new innovations for COVID?

02:23 Could you go into more detail, elaborate for us about this COVID-19 innovation around sequencing? 

04:25 Could you help us understand a little bit on what work is being done in those areas? 

07:47 Could you help our audience understand what have these conversation been like now that we’re into this pandemic this far, and the way that laboratory medicine testing is moving? I imagine you’re having more conversations with some of your Infectious Disease colleagues and you’re having more conversations with public health these days?

09:35 How do you answer that question?

11:18 Are there one or two COVID-related challenges that have really been running around in your mind the past week?

13:25 How is the Delta variant impacting what we’re thinking about for starting school?

14:38 Outro

Resources:
American Academy of Pediatrics

20 Dec 2024Being a Lifelong Learner00:22:04

In this episode of Lab Medicine Rounds, Justin Kreuter, M.D., speaks with education specialist Bob Jackson on the challenges and importance of being a lifelong learner.

Timestamps:
00:00 Introduction
00:31 Importance of lifelong learning
02:03 Challenges of lifelong learning
06:07 Adapting to change
10:58 Teaching and learning
13:39 Embracing uncertainty
17:00 Encouraging lifelong learning
24:00 New Year's resolutions

20 Sep 2024Trailblazing New Connections in Medicine00:17:40

In this episode of “Lab Medicine Rounds,” Justin Kreuter, M.D., interviews Shannon Strader, D.O., a resident in cellular therapy at Mayo Clinic in Rochester, Minnesota, to discuss trailblazing new connections in medicine.

Timestamps: 
0:00 Intro

00:56 Can you share your story with our listeners of how you connected the dots between physical medicine and rehab (PM&R) and cellular therapy?

04:54 What’s been those challenges and joys of working in the lab medicine world now?

08:38 You’re talking about your creativity, is that something that you’ve been able to tap into throughout your life during PM&R training, etc.?

10:24 What’s been your experience for the level of knowledge of cellular therapy in the physical medicine and rehab world? Is this something that people are aware of?

13:35 In what ways can laboratory professionals reach out and relationships with clinical colleagues?

15:31 What does the future of PM&R look like with cellular therapies in the toolbox?

17:13 Outro

07 Oct 2022Monkeypox: A Laboratory Medicine Perspective00:13:05

Timestamps:

0:00 Intro

00:45 Can you start us off by giving an overview of this latest outbreak of Monkeypox? And also if you could contrast that against Covid-19? 

03:25 What do you think this increase means for our hospital laboratories?

05:44 How can we provide the greatest value to our clinical colleagues and to our patients? 

08:17 I know we sometimes do culture a virus and look at viruses. Is it that testing that some of us have in our laboratories that’s not specific enough, it looks like other viruses, is that why we have other tests that we’re using?

10:00 Do you think that Monkeypox would be similar to Covid-19 where we have home test kits for the virus? 

12:21 Outro

25 Oct 2024The Art of Asking Questions00:21:07

In this episode of “Lab Medicine Rounds,” Justin Kreuter, M.D., interviews Timothy Long, M.D., about the importance of asking good questions in healthcare settings, such as when you’re with patients, as an educator, or at a conference or presentation. 

Timestamps:

00:00 Introduction
01:58 Developing the skill of asking good questions
06:37 Characteristics of effective questions
11:45 Effectively using questioning techniques as an educator
15:33 Considerations for asking questions in large group settings

24 Sep 2021Cytopathology: Cases, challenges, and advancements00:22:51
In this episode of Lab Medicine Rounds, Chris Hartley, M.D., Assistant Professor of Laboratory Medicine and Pathology at Mayo Clinic, discusses the topic of cytopathology, and what some of the challenges and advancements are.
07 Jun 2024The Science Behind Scleroderma00:19:05

In this episode of #LabMedicineRounds, Justin Kreuter, M.D., interviews Ashima Makol, M.B.B.S., for National Scleroderma Awareness Month, including a discussion about lab medicine's important role in diagnosis. 
 
Timestamps:
0:00 Intro
0:53 Why is it important for healthcare professionals to be aware of scleroderma? 
2:34 What are some important things for laboratory professionals to understand about scleroderma?
6:22 Rule in/rule out this rare diagnosis and help you understand where it fits within the scleroderma spectrum.
8:44 Is there something you would like to highlight about scleroderma?
11:58 Therapeutic or prognostic role in testing for scleroderma?
13:56 Can you give our audience a sense for how dynamic can this disease be?
16:05 What’s on the horizon for people diagnosed with scleroderma?
18:21 Outro

18 Feb 2022The Value of Pathology Interest Groups00:25:02

Timestamps:

00:00 Intro

01:32 From your points of view, why do you think it’s important to start a pathology interest group?

07:24 What are some important elements that you think are important for a successful interest group in your experience?

11:24 Is there one or two activities that really stands out that’s been perceived as the most valuable and best experiences so far?

13:18 Has there been any challenge with some faculty being able to explain or demonstrate their work, or is there any way to coach faculty during a session so they can truly show what is the work that they’re doing?

19:25 Has the pandemic had an impact on how you approached the pathology interest group?

23:07 What are your thoughts for how are you planning to be iterative and try next year, things that you didn’t try this year? What are ways that you’re interested in moving this forward?

26:20 Outro

03 Jan 2020New Year, New You, Same Genes!00:23:40

Time Stamps

00:00 Podcast Intro

00:42 When is a genetic test useful?

02:15 What situations would genetic testing not be helpful for?

03:15 Since pharmacogenomic testing isn’t useful for every drug, how do we know when it is useful? 

05:15 I’ve seen commercials for genetic testing. Can you talk about these?  

05:55 So, you’re saying that a private citizen could get some genetic testing performed?  

06:32 I imagine you have gotten a couple of phone calls from people asking what do to with their results? Do people sometimes call you about this?

07:44 Can you talk about the differences between what you are going to do in your lab when you’re doing pharmacogenomic testing and what might be available to a patient as a direct-to-consumer?

09:32 That makes me curious, does that mean that some of these direct-to-consumer tests are including alleles that are only for the white population? Or, are they including ones that are relevant to Latino, African-American, Asian communities too?

11:00 Is there genetic testing that can talk about what type of diet I should follow and what type of exercise I should be doing? 

12:45 Will everyone have their genomes sequences in a few years? 

15:18 Can you explain what you mean when you say the test is getting better overtime?

18:00 What is the role of the laboratory in performing a genetic test?

22:58 Outro

Additional Resources:
·  CPIC webpage http://cpicgx.org to see guidelines for pharmacogenomics

·  Genetic Testing Registry https://www.ncvi.nlm.nih.gov/gtr/ 

 

 

06 Sep 2024Clinical Updates on Thrombotic Thrombocytopenic Purpura (TTP)00:21:35

In this episode of “Lab Medicine Rounds,” Justin Kreuter, M.D., interviews Ewa Wysokinska, M.D., an assistant professor of medicine and consultant in the Division of Hematology and Medical Oncology at Mayo Clinic in Florida, to talk about clinical updates in thrombotic thrombocytopenic purpura.

06 Aug 2021Addressing the national blood shortage: Why blood inventory is so important00:21:56

Timestamps:

00:00 Intro

01:05 From your perspective, why is the blood inventory important to a hospital?

04:17 What have you learned about managing a hospital’s blood inventory these past 18 months or so?

08:09 I was wondering if you could give us a specific example on how are they trying to bridge that gap? 

08:55 Can you explain who the Dream Team is?

12:34 How does PVM look different on the hospital side? How is that being worked?

16:33 How might physicians, non-pathologists, help their hospital’s blood inventory? What are the practical things that is within their sphere of control that they can help?

20:52 What do you hope that our learners take away from these blood shortage challenges that we’re navigating right now?

23:20 Outro 

31 Jan 20202019 Novel Coronavirus (2019-nCoV): What You Need to Know00:18:27

Time Stamps

00:00 Podcast Intro

00:41 What do we know so far about the novel coronavirus? 

02:35 How does this novel coronavirus stack up to influenza?

04:35 Is there still value in getting your flu shot now (this year) if you haven’t gotten it yet?

05:08 Where should people go to get the latest and best information related to the novel coronavirus?

06:36 What should the health care provider be looking for related to the novel coronavirus?

08:18 I’m glad you mentioned the incubation period, is that something we know with this novel coronavirus?

 09:15 What do the laboratorians need to have in mind and what does this mean for the hospital clinical labs?

10:50 So, people can test positive for the coronavirus without having this specific novel coronavirus strain?

 12:02 So if somebody sent a sample down to a clinical lab, and I was truly positive for the novel coronavirus, I could have a negative result?

12:45 Can you elaborate on when a physician should pick up the phone relative to the new novel coronavirus outbreak?

14:43 Is there a risk to laboratory personnel for the infection to spread when they are handling the samples?

15:20 When should we be suspecting this novel coronavirus?

16:03 What should someone do if they suspect their patient has novel coronavirus?

16:33 As this is an evolving outbreak, where should folks go for the latest information?


Additional Resources:

·         Center for Disease Control (CDC)

·         World Health Organization (WHO)

29 Aug 2019Trailer: Lab Medicine Rounds Podcast 00:01:00

Coming Soon: Lab Medicine Rounds, a podcast to help you connect lab medicine and the clinical practice through insightful conversations. 

22 Oct 2021Lessons learned: Navigating the COVID-19 pandemic00:18:43

Timestamps:

00:00 Intro

01:22 Why is it important for labs to learn from their COVID-19 experiences?

05:34 Did you have any other lessons learned from this experience?

8:31 How are these meetings focused on maintaining a high quality? How did you manage the rest of your workload (developing new tests, etc.)?

12:51 Have some of those lessons from the experience of how those meetings were run, is there anything that you’re taking forward that you hadn’t been doing before COVID?

14:43 What do you think about those relationships between the laboratory and physicians, what have you heard from your clinical colleagues about what they’ve come to appreciate or something that they’ve learned about the laboratory that they are now taking forward in their practice?

18:25 Through this pandemic, what’s been your joy, how have you kept your heart full so that you can continue to work as hard as you have through this pandemic?

20:47 Outro

15 Nov 2019Advancements in Microbiology Diagnostics and the 16S Ribosomal RNA Gene00:17:18

Time Stamps

00:00 Podcast Intro

00:30 Introduction of Robin Patel, M.D. the Division Chair of Clinical Microbiology at Mayo Clinic 

00:42 What is the 16S Ribosomal RNA gene?

1:28  How is it detected and sequenced in clinical microbiology?

2:33 What does this mean for physicians and their patients now that this is something that can be done in the microbiology lab?

4:23 How has the testing for this gene changed?

5:58 Can you take us through an interesting case you have come across?

9:47 What are the limitations when you’re talking about this kind of testing?

11:15 Where is this headed? Are we headed towards next-gen sequencing for 16S?

11:51 So, that will be helpful when you’re talking about using it directly on a patient sample vs. a pure colony that you’re using the testing on?

12:29 What’s the turnaround time for this kind of test? 

14:08 Where does this 16S Ribosomal RNA gene testing fit in the toolbox of who should be ordering this?

15:21 What is it that you wish the medical community knew about the microbiology lab?

16:34 Outro

Resources:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652441/
https://jcm.asm.org/content/55/9/2599 

18 Mar 2022Wellness: What's Your Why?00:21:32

00:00 Intro

00:58 Why are wellness efforts a need-to-have, rather than a want-to-have?

04:18 What are we learning about wellness that is important for our audience to understand?


07:44 What are those first steps that our listeners can take and initiate for their own local practice, what would their initial support look like?


14:23 Are there classic struggles with improving wellness that you can help our listeners navigate if there are some pearls to share in that regard?


22:01 What do you think is in store for us in the future?


23:52 Outro

08 Oct 2021Being a professional on social media: Challenges and opportunities 00:18:00

Timestamps:

00:00 Intro

01:02 What are a few of the potential risks and benefits of using social media as a professional? Why should I be doing this and thinking about it?

03:31 People can adjust their privacy settings on social media, so why is it important for healthcare professionals and students to behave professionally on social media? 

06:08 Some might say that there are several shades of gray when it comes to professionalism. So, what do we need to understand about professionalism on social media?

08:44 I understand that you have some things you’ve helped students and faculty navigate social media, can you share a few of those significant challenges with us?

13:15 What are a few tips for people just getting started?

17:38 What’s your view of professional use of social media?

19:58 Outro

20 Apr 2020The People Behind the Lab Bench00:25:57

00:00 Podcast Intro 

00:56  On a lot of T.V. shows that I’ve watched over the years, I see the surgeons and emergency medicine docs after they see the patient pop back in the lab and perform those critical tests. In reality, is that really what’s going on? 

01:42 Myself as a pathologist, I understand for a lot of physicians I’m probably one degree removed from the bedside, so one degree outside of their mind, and  maybe the medical technologist is another degree. So for our physicians and clinicians listening to this podcast, can you maybe share some of the biggest misconceptions about laboratory technologists and the value that they are actually contributing behind the scenes to that patient care?

03:05 I know in our day to day we kind of think about those patients or situations where we’ve really been challenged and made a difference for the patient. Can you share one of those stories about where you specifically really played a role behind the scenes that made a difference for patient care?

04:39 It sounds like you guys really are the both the first and last line of defense on making sure that the information that is coming out of the laboratory is as accurate as possible?

05:25 You know that front end is really something to highlight for our listeners about, we all got used to ordering tests based on how we were trained and what was available at the time we are training, and as with all things, medical science continues to advance. I think that’s a critical point to make. That Medical Technologist is really up to date on what is an older test, or what test is best to answer that question the physician has?

06:46 If you could elaborate a little bit for students who are just starting to consider this field and maybe even, are there some thoughts for some people who are just starting in laboratory medicine about what the best path might be for them?

8:05 So you’re saying that if I’m somebody that likes variety in my day, there’s a place for me in laboratory medical science, and if I like being an expert in something, there’s ALSO a place for me in laboratory medical science?

08:35 You’ve had a really interesting and valuable career and you’ve kind of seen this profession from a couple of different angles. I was wondering if you have any words of wisdom for someone who is maybe just getting started in laboratory medical science in those first 3-5 years of practice? Do you have any advice for them as to what should they be focusing on and thinking about from a coaching perspective?

13:43 Are there any plans for sharing laboratory pride this year (for Lab Week)?

14:29 Do you have any kind of messages for how pathologists can work best with their laboratory technologists?

16:38 Can you share how you found this field of laboratory science?

21:26 What qualities make for a good lab tech?

25:00 Outro 

 

Resources:
Career Exploration: https://ascls.org/

21 Apr 2023Shared Experience: Participating on a Laboratory Inspection Team00:16:07

In this episode of “Lab Medicine Rounds,” Justin Kreuter, M.D., sits down with Emily Shaffer, D.O., a resident physician in pathology and laboratory medicine for Northwell Health in Roslyn, New York, to talk about her experience participating on a laboratory inspection team.

Timestamps:

0:00 Intro

00:53 What is your origin story for becoming a pathologist?

02:06 What was your experience like participating in a laboratory inspection?

03:18 Was there any kind of prep beforehand that you did, or what was the actual inspection day(s) like? How did that unfold?

05:34 Were there people at your home laboratory that were taking you through what that might look like, or questions you might ask?

07:03 Was the lab you inspected a bit similar to your home laboratory? What was that like?

08:20 Was this a one-day inspection, or did it lead into two days?

09:12 I’m kind of curious about that mentorship that happened; was that something the site leader discussed with you ahead of time?

10:56 What is your reflection on what you took away from this experience? 

12:54 Do you have any reflections on having gone through this experience now, is there one or two ways you think the listeners who are educators might think about improving the way we teach quality and regulatory in our programs?

14:17 Can you mention the steps on approaching the College of American Pathologists (CAP) to do an inspection for those who are interested?

15:24 Outro

04 Feb 2022Six Questions00:08:15

We appreciate any feedback you have time to provide, in order to inform the future of the "Lab Medicine Rounds" podcast. No questions are required. Please take the short, anonymous, six question survey here: https://surveys.mayoclinic.org/jfe/form/SV_di0Wjubj6GAce10 

24 Jul 2020Being Deliberate when Starting Your Career in Pathology00:28:30

Time Stamps

00:00 Podcast Intro

00:51 This is a nice time of year for the academic calendar with new trainees starting residency, and new faculty starting their jobs, and people still in their first couple of years of being an academic pathologist. Why is it important for these individuals to be deliberate about how they begin their career?

04:18 When somebody is in training, there is a lot that is decided for them and things are predetermined. In residency that opens up quite a bit. Can you give us some insight into these goals you are talking about? On a smaller scale, how do you set yourself up so you can be consistent in making progress?

07:55 Are you pretty deliberate about revisiting where you are with your goals? How do you check yourself?

10:30 Your success as a resident and as an attending, what advice works in both roles and what advice is good for a resident versus the attending?

13:53 When evaluating trainees there is a component regarding delegating work. The skill is critical to have when coming on staff either in an academic or nonacademic setting. Is there a way that you prepare trainees to develop their skills in delegating?

17:05 Sometimes things take you by surprise, which is a great learning opportunity. You have really navigated the system quiet well. I’m curious, what has been easy about this process and what has really been a challenge?

19:55 If you could do it all over again, what would you do differently this time?

25:22 Getting feedback and developing relationship the way you can be, is that a lost opportunity?

11 Oct 2024Interview Tips for Pathology Residents00:21:17

In this episode of “Lab Medicine Rounds,” Justin Kreuter, M.D., interviews Reade Quinton, M.D., an associate professor of laboratory medicine and pathology and anatomic pathologist at Mayo Clinic, to discuss interview tips for future pathology residents. 

Timestamps:
0:00 Introduction
0:45 Interviewer assessment
7:07 Communication style & personality
10:25 Asking questions to help with rank lists
17:45 Follow-up after interview
22:09 Outro

09 Jul 2021Understanding medical ethics00:26:16

Timestamps:

00:00 Intro

01:19 Could you help us understand, why should I consider getting an ethics consult? What value could this bring to my clinical practice?

07:49 What should our audience understand in order to really work better with our local med ethics team?

13:58 Could you help us understand about organizational ethics? How does that compare and contrast with that hospital ethics committee that you said everybody has and are most used to turning to?

22:24 What would be your recommendation for how to reach out to who is doing organizational ethics at our institution?  

25:00 I was wondering if you would be willing to share one or two predictions for the future of medical ethics to open our mind up to what are the main issues and questions, and how is your field evolving? 

30:35 Outro 

05 Apr 2024Drawing the Line: The Rationale Behind Blood Tube Collection Order00:20:13

In this episode of “Lab Medicine Rounds,” host Justin Kreuter, M.D., speaks with Brooke Katzman, Ph.D., to discuss the blood tube collection order.

Show Notes:
0:00 Intro
0:41 Rational of blood tube order
3:15 Direct and indirect contamination
4:58 Draw order
8:11 Serum vs. Plasma
10:23 Testing for specific analytes
12:39 Interferences
14:38 Teaching order of draw
17:22 Best practices
20:41 Closing

06 Sep 2019Top Five Things Every Medical Professional Should Know about Lab Medicine00:18:14

Time Stamps

00:00 Podcast Intro

00:32 Introduction of Ann Moyer, M.D., Ph.D.  

00:49 How did you decide to go into Molecular Genetic Pathology?

2:33 What do you do all day (as a pathologist)?

4:25 Can you take one test and talk us through how you look at a case?

7:32 What’s your favorite part about being a pathologist?

8:28 What’s the worst aspect?

9:18 Is it true that a lot of the tests that are run in your lab didn’t exist five years ago?

10:20 What have you learned on the job that you weren’t exposed to in your training?

11:36 How can clinicians build that bridge of collaboration with their pathologist?

13:11  What would you tell medical students as to why they should consider pathology?

14:39 What are the top five things that medical professionals should know about laboratory medicine?

17:39 Outro

04 Apr 2025Leading up to Lab Week: Recognizing the Role of Laboratory Professionals00:10:05

As we approach Lab Week, this episode of “Lab Medicine Rounds” includes a compilation of interviews from previous episodes highlighting the pivotal role laboratory professionals play in healthcare. Featured interviews include Dr. Eric Hsi, Dr. Curt Hanson, and Jane Hermansen, all from Mayo Clinic in Rochester, Minnesota.

Discussion includes:

·       The importance of highlighting the laboratory presence in current medical practice.

·       How laboratory medicine is informing the future successes of the field.

·       Wishes for the future of laboratory medicine and pathology.

Timestamps:


00:30: Interview w/Dr. Hsi

·       Why is it important to highlight the presence of the laboratory in current medical practice?

·       What would be your advice for clinicians who haven’t thought about the role the laboratory plays, and how to bring it more explicitly into their practice?

·       Where is the laboratory headed? 

·       What do you think might be the biggest challenge in stepping forward into more of the clinical domain?

05:32: Interview w/Dr. Hanson

·       Why is it important in lab medicine to look at the past when planning for the future?

·       How do you see certain aspects of laboratory medicine informing the future successes of the field?

·       How do we as laboratory professionals, shift from being service-oriented to being colleagues/equals with other health care professionals?

07:45: Interview w/Jane Hermansen

·       What do you wish for the future of laboratory medicine and pathology?

07 May 2021Sustainable bridges: Lab medicine & cardiology00:19:10

Timestamps:

00:00 Intro

01:00 Can you give us the lay of the land and explain how does the cardiovascular laboratory provide patient care?

03:24 Can you elaborate for us what it looks like when you have clinical chemists, cardiologists, and other professionals with different backgrounds working together?

05:56 Can you talk about bringing these people into the laboratory and developing a test that provides a lot of value to patients? How is that blended and what’s the output?

07:31 Talking about meetings that you guys do -- how is this meeting not some hierarchy of people who come together? How do these meetings work as an interprofessional utopia?   

11:21 How do you keep your clinical colleagues educated about laboratory science?

14:25 Are other laboratories adopting this leadership model?

15:42 What have you learned about establishing the culture and getting them to understand what the plan is?

17:59 Turning to medical laboratory scientists, what’s your pitch for why they should go into clinical chemistry?

 

20:12 Outro 

21 May 2021Cardiovascular laboratory: Biomarkers, testing, & clinical implications 00:18:42

Timestamps:

00:00 Intro

01:00 How does the cardiovascular laboratory support patient care?

01:47 Can you tell us a bit about ceramides? What are they?

04:14 When should ceramides be tested? 

06:04 Can you modify someone’s ceramides such that the test can be repeated and monitored, or is it once in a lifetime because ceramides or more static?

08:05 What is the controversary around ceramides? 

09:52 Could you give our listeners an introduction to Lipoprotein(a)?

11:45 Who should be tested for Lipoprotein(a)?

13:59 How do we treat elevated Lipoprotein(a)? 

17:20 How did your interests in laboratory medicine develop? How has this brought meaning for you in your career professionally? 

19:23 Outro

Resources:
1.  Ceramides and Ceramide Scores: Clinical Applications for Cardiometabolic Risk Stratification. Hilvo M, Vasile VC, Donato LJ, Hurme R, Laaksonen R. Front Endocrinol (Lausanne). 2020 Sep 29;11:570628. doi: 10.3389/fendo.2020.570628. eCollection 2020. PMID: 33133018 Free PMC article. Review.

2.  Measuring the contribution of Lp(a) cholesterol towards LDL-C interpretation. Fatica EM, Meeusen JW, Vasile VC, Jaffe AS, Donato LJ. Clin Biochem. 2020 Dec;86:45-51. doi: 10.1016/j.clinbiochem.2020.09.007. Epub 2020 Sep 28. PMID: 32997972

3.  Ceramides improve atherosclerotic cardiovascular disease risk assessment beyond standard risk factors. Meeusen JW, Donato LJ, Kopecky SL, Vasile VC, Jaffe AS, Laaksonen R. Clin Chim Acta. 2020 Dec;511:138-142. doi: 10.1016/j.cca.2020.10.005. Epub 2020 Oct 12. PMID: 33058843

4.  Ceramide Scores Predict Cardiovascular Risk in the Community. Vasile VC, Meeusen JW, Medina Inojosa JR, Donato LJ, Scott CG, Hyun MS, Vinciguerra M, Rodeheffer RR, Lopez-Jimenez F, Jaffe AS. Arterioscler Thromb Vasc Biol. 2021 Apr;41(4):1558-1569. doi: 10.1161/ATVBAHA.120.315530. Epub 2021 Feb 18. PMID: 33596665

5.  High-Sensitivity Cardiac Troponin for the Diagnosis of Patients with Acute Coronary Syndromes. Vasile VC, Jaffe AS. Curr Cardiol Rep. 2017 Aug 24;19(10):92. doi: 10.1007/s11886-017-0904-4. PMID: 28840515 Review.

6.  Natriuretic Peptides and Analytical Barriers. Vasile VC, Jaffe AS. Clin Chem. 2017 Jan;63(1):50-58. doi: 10.1373/clinchem.2016.254714. Epub 2016 Oct 10. PMID: 28062611 Review.

7.  Diseased skeletal muscle: a noncardiac source of increased circulating concentrations of cardiac troponin T. Jaffe AS, Vasile VC, Milone M, Saenger AK, Olson KN, Apple FS. J Am Coll Cardiol. 2011 Oct 18;58(17):1819-24. doi: 10.1016/j.jacc.2011.08.026. Epub 2011 Sep 29. PMID: 21962825

8.  Elevated cardiac troponin T levels in critically ill patients with sepsis. Vasile VC, Chai HS, Abdeldayem D, Afessa B, Jaffe AS. Am J Med. 2013 Dec;126(12):1114-21. doi: 10.1016/j.amjmed.2013.06.029. Epub 2013 Sep 28. PMID: 24083646

16 Apr 2021Forensic pathology 10100:21:23

00:00 Intro

01:15 What’s your origin story? How did you become a forensic pathologist?

03:53 What are some of the misconceptions about forensic pathology?

06:15 Is there a big public health component to forensic pathology?

07:29 Covid is a nice example on how you have partnered with public health, can you elaborate more on that?  

10:15 What other types of physicians are you interacting with periodically and what are those conversations about?

13:10 Do you approach autopsies differently depending on the case at hand?

17:30 In what ways is the field of forensic pathology continuing to evolve and grow?

20:50 Outro 

02 Oct 2020Update: Convalescent Plasma00:24:31

Time Stamps

00:00 Podcast Intro

00:35 Now that the EAP is closed, how are doctors getting convalescent plasma for their patients?

 

08:50 What new information have we learned about convalescent plasma in recent months?

 

13:28 If we are in a period of shortage and there is only low titer available, is it ideal to transfer two units of convalescent plasma in that context?

15:30 What remaining questions about convalescent plasma are you most curious about?

18:52 How can study design enable or inhibit certain questions to be asked and answered?

21:00 Are there any additional transfusion therapies on the horizon?

23:50 Outro 

03 Nov 2023What's New in CAR-T?00:18:42

In this episode of “Lab Medicine Rounds,” host Justin Kreuter, M.D., speaks with Timothy Wiltshire, Ph.D., assistant professor of laboratory medicine and pathology in the Division of Transfusion Medicine, to discuss what’s new with CAR-T cells.
 
Timestamps:
0:00 Introduction
0:49 Why is CAR-T important for healthcare folks to appreciate in 2023?
3:05 What should healthcare professionals understand about CAR-T?
4:55 Is it true to say that we’ve seen success specifically in the hematologic cancers like leukemias, but not necessarily like the solid tumors, like breast cancer or prostate cancer?
7:27 Are there a few things that you look for when you read an article that’s reporting about CAR-T cells?
10:24 Can you explain what off-target effects are? 
11:46 What are some of the new things that have come out recently?
13:24 What’s involved with creating your typical CAR-T?
14:58 What are your thoughts on the future for the field?
16:22 Is this a more equitable product or are there still some struggles with getting equity for different populations with CAR-T?
17:25 Is the promise of an off-the-shelf not just for an emergency, but could that be a cheaper option?
18:00 Outro 

 

01 Nov 2019Clinical Decision Support: Making It Easy to Do the Right Thing00:27:56

Time Stamps

00:00 Podcast Intro

00:58 What is clinical decision support? How does that fit in to patient blood management?

02:37 Can you tell us how clinical decision support is similar to education and how it is a little different than straight forward education?

04:53 How do you make clinical decision support successful? 

07:11 Can you share how the collaboration between you and IT has gone? How have you navigated to make sure you can come out with the best and most meaningful clinical support?

10:14 What are some of the pitfalls from implementing clinical decision support? 

13:55 Will you share your thoughts on evaluating a clinical decision support program?

16:33 It sounds like there is a lot of quantitative measurements, how about qualitative measurements?

17:45 What has surprised you most about patient blood management? 

19:39 What does the future look like regarding clinical decision support?

21:33 As a bedside physician, what do you wish the laboratory understood about your practice?

25:01 Can you share a personal story on how reaching out to the lab has made a difference for one of your patients?

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