Dr. GPCR Podcast (Dr. Yamina Berchiche)

Watch the video version of this podcast episode 

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Become a #DrGPCR Ecosystem Member 

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For more details, visit the #DrGPCR Podcast Episode #86 page

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Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• Individuals
• Organizations

-------------------------------------------

Are you a #GPCR professional?

• Subscribe to #DrGPCR Monthly Newsletter
• Listen and subscribe to #DrGPCR Podcasts
• Listen and watch GPCR focused scientific talks at #VirtualCafe

Have you had moments that defined your scientific tastes? For Dr. J Silvio Gutkind, a class on oncogenes and his interests for GPCRs helped shape his scientific interests. These took him from the University of Buenos Aires in Argentina to UC San Diego and through the National Institutes of Health in Bethesda, Maryland. In this episode, Silvio discusses G protein signaling in the context of cancer, immunotherapies, and combination therapies that could help improve patients’ lives.

For more details, visit #DrGPCR Podcast Episode #64 page

https://www.drgpcr.com/episode-64-with-dr-dylan-eiger/

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About Dylan Eiger

Dylan Eiger is currently an MD/Ph.D. student at Duke University School of Medicine. He received his B.S. in Chemistry from Duke University in 2016 where he worked in the lab of Dr. Stephen Craig and studied polymer chemistry and material science.

He is currently finishing his Ph.D. in the lab of Dr. Sudarshan Rajagopal, a former postdoctoral fellow of Dr. Robert J. Lefkowitz. Dylan's graduate research focuses on the mechanisms underlying biased signaling at GPCRs, specifically, the role of differential receptor phosphorylation (phosphorylation barcodes) and subcellular GPCR signaling in directing functionally selective responses. He primarily studies the chemokine receptor CXCR3 as it has three naturally occurring ligands and thus serves as an endogenous example of biased agonism.

After finishing his MD/Ph.D., Dylan plans to complete his residency training in Internal Medicine and subsequently pursue fellowship training in Cardiology. He hopes to continue his research on biased agonism at GPCRs with a particular focus on the treatment of cardiovascular disease.

Dylan Eiger on the web

• LinkedIn
• Twitter
• PubMed
• Website

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We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

Fill out the Ecosystem waitlist form today to be the first to explore our brand new and improved space!

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

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Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

-   Watch recorded #DRGPCR Virtual Cafe presentations:

https://www.youtube.com/channel/UCJvKL3smMEEXBulKdgT_yCw

-   Share your feedback with us:

http://www.drgpcr.com/audience-survey/

⁠Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠

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⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

⁠⁠Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠

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⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

Dr. Pluznick discovered that olfactory receptors in mice are also expressed in their kidneys and blood vessels. Her research is focused on the role of chemosensory GPCRs in regulating renal and cardiovascular function, and identifying renal/cardiovascular olfactory receptor ligands, and relating them to whole-animal physiology. This work contributes to a better understanding of how the kidney helps maintain homeostasis in humans.

Jennifer is currently an assistant professor of physiology at the Johns Hopkins School of Medicine. She received her undergraduate degree in biology from Truman State University and earned her Ph.D. in renal physiology from the University of Nebraska Medical Center. She then spent five years training as a postdoctoral fellow in the laboratory of Michael Caplan at Yale University, where she studied both renal physiology and sensory biology systems and focused on olfaction.

It was December 14th, 2020, 1:50 pm, when I turned on my laptop and signed into Zoom for my chat with Bob.

Bob, who, you might ask?

Well, it’s the one and only Robert J. Lefkowitz, M.D., 2012 Nobel Prize in Chemistry, which he shared with Dr. Brian Kobilka. Bob doesn’t really need an introduction since his reputation precedes him. Before we pressed record, I asked if I could call him Bob, and he answered that only his mom used to call him Robert, especially when she was upset with him. I then pressed record, and we chatted for almost 2h about Bob’s career, discoveries, difficulties (yes, he’s had some too), Nobel week, and his memoir that he just published in collaboration with Dr. Randy Hall.

Bob is James B. Duke Professor of Medicine and Professor of Biochemistry, Chemistry, and Pathology at the Duke University Medical Center. He began his career in the late 1960s and has been an Investigator of the Howard Hughes Medical Institute since 1976. His legacy lies in the numerous discoveries he and his team made in the GPCR field and in all those who trained in his laboratory and went on to pursue stellar scientific careers.

I very much enjoyed chatting with Bob, and I hope you’ll enjoy learning more about him as well.

http://www.drgpcr.com/episode-27-dr.-robert-j-lefkowitz/

Dr. Kathryn E Livingston is currently a Product Manager at Gator Bio, a biotechnology company providing solutions to researchers studying protein-protein interactions. Kathryn obtained her BS in Chemistry from Carnegie Mellon University and went on to receive a Ph.D. in Pharmacology at the University of Michigan. Working under the supervision of Dr. John Traynor, Kathryn worked to develop and understand first-in-class allosteric modulators of opioid receptors. Research into their mechanism of action in purified systems formed the base of her thesis work. Following this, Kathryn did a post-doctoral fellowship at UCSF in the laboratory of Dr. Mark von Zastrow. There she researched the beta-2 adrenergic receptor and developed assays to investigate real-time activity in intact cellular systems. Kathryn’s passion is developing solutions to problems in whatever form is most efficient: novel instrumentation, novel methods, or novel communication.

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Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

-   Watch recorded #DRGPCR Virtual Cafe presentations:

https://www.youtube.com/channel/UCJvKL3smMEEXBulKdgT_yCw

-   Bring in a #GPCR Consultant

http://www.drgpcr.com/consulting/

-   Share your feedback with us:

http://www.drgpcr.com/audience-survey/

-   Become a #DrGPCR Ecosystem Member

http://www.drgpcr.com/membership/

Dr. Maria Waldhoer is originally from Austria. She earned her M.Sc. in Zoology and Neurobiology before completing a Ph.D. in Biology and Pharmacology at the University of Vienna. GPCRs led Maria to Thue W. Schwartz’s lab in Copenhagen where she completed her postdoctoral training. After working in the US and at the University in Graz in Austria, Maria worked several years at Novo Nordisk before joining InterAx Biotech in Switzerland as their Chief Scientific Officer. Even though Maria stumbled upon the GPCR field, her 20 years in both academia and in the industry working on GPCRs make her a strong and dedicated scientific leader.

Watch the video version of this podcast episode.⁠⁠

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⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠Individuals⁠⁠
• ⁠⁠Organizations⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠
• ⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠
• ⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠.

Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

Watch the video version of this podcast episode 

https://www.ecosystem.drgpcr.com/dr-gpcr-podcast

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Learn more about Dr. Nicola J. Smith 

https://www.ecosystem.drgpcr.com/search?q=Nicola+Smith

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How Users can benefit Dr. GPCR Ecosystem? 

https://www.ecosystem.drgpcr.com/explore-individuals

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How Organizations can benefit from Dr. GPCR Ecosystem? 

https://www.ecosystem.drgpcr.com/explore-organizations

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Become a #DrGPCR Ecosystem Member 

https://www.ecosystem.drgpcr.com/plans-pricing

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Imagine a world in which the vast majority of us are healthy.  

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.   

To build our #GPCR Ecosystem, we created various enabling outlets.  

- Individuals 

https://www.ecosystem.drgpcr.com/explore-individuals 

- Organizations 

https://www.ecosystem.drgpcr.com/explore-organizations

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Are you a #GPCR professional?   

-   Subscribe to #DrGPCR monthly newsletter 

http://www.drgpcr.com/newsletter/ 

-   Listen and subscribe to #DrGPCR Podcasts  

http://www.drgpcr.com/podcast/ 

-   Listen and watch GPCR focused scientific talks at #VirtualCafe 

https://www.drgpcr.com/virtual-cafe/

Listen to this fantastic round table discussion that I had the privilege to moderate with Alexander Hauser. Our guests were Maria Waldhoer, Tudor I. Oprea , Thomas Sakmar, Aurelien Rizk & Yaroslav Nikolaev.

The explosion of biomedical data such as in genomics, structural biology, and pharmacology can provide new opportunities to improve our understanding of human physiology and disease. In recent years, machine learning (ML) and artificial intelligence (AI) methods have received a significant boost of attention. ML/AI can be powerful for identifying abstract patterns within large data where traditional methods would be oblivious to. This comes without the need for manual feature engineering as systems can learn through implicit rules from the data provided. G protein-coupled receptors (GPCRs) mediate a vast variety of critical biological processes and provide an ideal case study for quantitative, and multi‐scale integration of these amounts of data to gain novel insights into receptor biology. How can we best leverage these exciting new techniques in areas such as protein structure prediction, bioactive ligand discovery, in vivo translationability or in our understanding of signalling determinants? Here, we would like to discuss opportunities, weaknesses, and advantages of these new technologies, which may contribute to probe our favorite targets at all scales.4- Banner photo:

Dr. Chris Tate obtained his Ph.D. from the University of Bristol in 1989 and then moved to the University of Cambridge (Dept of Biochemistry) to work on bacterial sugar transporters. In 2005 he started working on the development of conformational thermostabilization of GPCRs, which resulted in the structure of the β1-adrenoceptor. In 2016 mini-G proteins were developed as a tool for the structure determination of GPCRs in the fully active state. Join me to learn more about Chris’s work and his love for science.

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Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. 

To build our #GPCR Ecosystem, we created various enabling outlets.

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

Are you a #GPCR professional? 

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/ 

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts 

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

-   Watch recorded #DRGPCR Virtual Cafe presentations:

https://www.youtube.com/channel/UCJvKL3smMEEXBulKdgT_yCw

-   Bring in a #GPCR Consultant

http://www.drgpcr.com/consulting/

-   Share your feedback with us:

http://www.drgpcr.com/audience-survey/

-   Become a #DrGPCR Ecosystem Member

http://www.drgpcr.com/membership/

For more details, visit the #DrGPCR Podcast Episode #77 page

https://www.drgpcr.com/episode-77-with-Martin-Audet/

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About Dr. Martin Audet

Structural biologist, pharmacologist, and a professor of pharmacology at Université de Sherbrooke. He is the head of the AudetLab located at the Institute of Pharmacology of Sherbrooke and is an emerging leader in the structural biology of G Protein-Coupled Receptors and passive transporters. Strong education with a Doctor of Philosophy (Ph.D.) in biochemistry under the supervision of Michel Bouvier at Université de Montréal, followed by a Postdoctoral Fellow at Scripps Research in San Diego and the University of Southern California in Los Angeles as a member of Raymond Stevens group.

Dr. Martin Audet on the web

• LinkedIn
• Twitter
• Sherbrooke University
• Google Scholar

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Become a #DrGPCR Ecosystem Member

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

• Individuals
• Organizations

-------------------------------------------

Are you a #GPCR professional?

• Subscribe to #DrGPCR Monthly Newsletter
• Listen and subscribe to #DrGPCR Podcasts
• Listen and watch GPCR focused scientific talks at #VirtualCafe

Watch the video version of this podcast episode.

-------------------------------------------

Become a #DrGPCR Ecosystem Member 

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• Individuals
• Organizations

-------------------------------------------

Are you a #GPCR professional?

• Subscribe to #DrGPCR Monthly Newsletter
• Listen and subscribe to #DrGPCR Podcasts
• Listen and watch GPCR-focused scientific talks at #VirtualCafe.

For more details, visit the #DrGPCR Podcast Episode #78 page

https://www.drgpcr.com/episode-78-with-stuart-maudsley/ 

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About Dr. Stuart Maudsley

Stuart graduated from the University of Leeds in the U.K. with a First Class Honors degree in Pharmacology. At the end of his studies, he was awarded the Pfizer Prize for undergraduate research. He then completed his Ph.D. at Leeds as well as the University’s Ackroyd, Brotherton, and Brown Scholar.

Following his Ph.D., Dr. Maudsley was awarded a Howard Hughes Medical Institute Fellowship to train with Professor Robert Lefkowitz at Duke University. Following this tremendous experience, he was recruited to be the Principal Investigator of the Receptor Biology Section at the Medical Research Council (MRC) -Human Reproductive Sciences Unit within the University of Edinburgh.

At the MRC he developed novel prostate cancer therapeutics based upon his research into GPCR pluridimensional signaling. To broaden his biomedical skill-set Stuart next accepted the position of Head of the Receptor Pharmacology Unit at the National Institutes of Health – National Institute on Aging at the Johns Hopkins University Medical Center. At the NIH he was the recipient of the coveted NIH ‘Bench-to-Bedside’ Translational Research Grant Award, one of the few awards available within the intramural NIH program. Upon starting a new family, and returning to Europe, Dr. Maudsley continued his scientific journey with the award of the highly-valued Odysseus Program Type I Program Grant to work as both the Adjunct Director of the VIB Center for Molecular Neurology and also Vice-Chair of the Department of Biomedical Sciences at the University of Antwerp.

Stuart’s current research, in the Receptor Biology Lab, focuses on the development of novel GPCR-based therapeutics that interdict diseases based on their gerontological underpinnings. This research stream is now forming the basis of a new technology-based start-up company, HeptOME, to help screen and develop novel longevity/disease-regulating compounds with multidimensional disease efficacy profiles.

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Become a #DrGPCR Ecosystem Member

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

• Individuals
• Organizations

-------------------------------------------

Are you a #GPCR professional?

• Subscribe to #DrGPCR Monthly Newsletter
• Listen and subscribe to #DrGPCR Podcasts
• Listen and watch GPCR focused scientific talks at #VirtualCafe

Watch the video version of this podcast episode.

-------------------------------------------

Become a #DrGPCR Ecosystem Member 

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• Individuals
• Organizations

-------------------------------------------

Are you a #GPCR professional?

• Subscribe to #DrGPCR Monthly Newsletter
• Listen and subscribe to #DrGPCR Podcasts
• Listen and watch GPCR-focused scientific talks at #VirtualCafe.

Watch the video version of this podcast episode 

-------------------------------------------

Become a #DrGPCR Ecosystem Member 

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• Individuals
• Organizations

-------------------------------------------

Are you a #GPCR professional?

• Subscribe to #DrGPCR Monthly Newsletter
• Listen and subscribe to #DrGPCR Podcasts
• Listen and watch GPCR-focused scientific talks at #VirtualCafe.

Eleonora Comeo is a doctoral candidate in Medicinal Chemistry and Drug Discovery in the joint program of the University of Nottingham in the UK and Monash University in Australia. We sat down to chat about GPCRs, synthesizing labeled ligands, and her unique position that allows her to work with GPCR scientists on 2 continents. We also touched on how COVID-19 affected her Ph.D. work.

Watch the video version of this podcast episode.⁠⁠⁠⁠⁠

-------------------------------------------

⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠.

To read the full #Newsletter click here:

https://www.drgpcr.com/november-2021/

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Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

In this episode of the Dr.GPCR podcast, my guest is Dr. Arun Shukla from the Indian Institute of Technology in Kanpur, India. Arun is currently an Associate Professor & Joy Gill Chair Professor, Intermediate Fellow, Wellcome Trust DBT India Alliance

Swarnajayanti Fellow & EMBO Young Investigator at the Department of Biological Sciences and Bioengineering. He earned his master's degree in biotechnology from Jawaharlal Nehru University in India and it was during a biochemistry class where he learned about cell signaling that he became curious and wanted to learn more about it. Arun first started working on GPCRs and their structural characterization at the Max Planck Institute of Biophysics where he completed his doctoral studies in the lab of Dr. Hartmut Michel.

Fascinated by GPCRs he wrote to Dr. Bob Lefkowitz and asked him if he could join his lab at Duke University. Dr. Shukla spent several years in the Lefkowitz lab and collaborated extensively with Dr. Brian Kolbika of Stanford University.

Join us and learn more about Dr. Shukla’s research and how working in the lab instead of going to classes made him realize that research is what he wants to do for the rest of his life.

⁠⁠Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠

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⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

Watch the video version of this podcast episode 

------------------------------------------- 

Become a #DrGPCR Ecosystem Member 

-------------------------------------------

For more details, visit the #DrGPCR Podcast Episode #90 page

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• Individuals
• Organizations

-------------------------------------------

Are you a #GPCR professional?

• Subscribe to #DrGPCR Monthly Newsletter
• Listen and subscribe to #DrGPCR Podcasts
• Listen and watch GPCR focused scientific talks at #VirtualCafe

Watch the video version of this podcast episode.

-------------------------------------------

Become a #DrGPCR Ecosystem Member 

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• Individuals
• Organizations

-------------------------------------------

Are you a #GPCR professional?

• Subscribe to #DrGPCR Monthly Newsletter
• Listen and subscribe to #DrGPCR Podcasts
• Listen and watch GPCR-focused scientific talks at #VirtualCafe.

For more details, visit the #DrGPCR Podcast Episode #74 page

http://www.drgpcr.com/episode-74-with-dr-daniel-wacker/

-------------------------------------------

About Dr. Daniel Wacker

I obtained my B.Sc. degree from the University of Munich performing work in the lab of Dr. Roland Beckmann with a brief stay at Cambridge University, UK, working in the lab of the late Dr. Kiyoshi Nagai. I then obtained an M.Sc. at the University in Munich working e.g. in the lab of Patrick Cramer. I next moved to Rockefeller University in NYC to work in the lab of the late Dr. Guenter Blobel, before starting my Ph.D. in 2009 at The Scripps Research Institute in La Jolla. There I obtained my Ph.D. in the lab of Dr. Ray Stevens in 2013 solving several GPCR crystal structures, including that of the first serotonin receptor. I then moved to UNC at Chapel Hill to do postdoctoral work in the lab of Dr. Bryan Roth where I established GPCR structural biology and learned the ins and outs of molecular pharmacology and in vitro drug discovery. In 2018 I started my own lab at the Icahn School of Medicine at Mount Sinai in NYC, where I have been working on structure-function and drug discovery of GPCRs and transporters.

Dr. Daniel Wacker on the web

• Website
• LinkedIn
• Twitter
• PubMed

-------------------------------------------

We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

Fill out the Ecosystem waitlist form today to be the first to explore our brand new and improved space!

For more details, visit our website http://www.DrGPCR.com/Ecosystem/

About Dr. JoAnn Trejo

Dr. JoAnn Trejo earned her Ph.D. at UC San Diego. She completed her postdoctoral fellowship at UC San Francisco under the guidance of Professor Shaun Coughlin where she worked on the newly discovered protease-activated GPCRs. Dr. Trejo joined the faculty in the Department of Pharmacology at the University of North Carolina in 2000 and then moved to UC San Diego School Medicine, Department of Pharmacology in 2008, where she quickly rose through the ranks to tenured professor in 2012. In 2014, she was appointed Vice-Chair of the Department of Pharmacology.

The long-term goal of Dr. Trejo’s research program is to gain a thorough and mechanistic understanding of processes that control cell signaling by protease-activated receptors (PARs) and the impact on vascular inflammation and cancer progression. PARs are GPCRs that are activated through an atypical irreversible proteolytic mechanism. The precise control of PAR signaling is critical for proper temporal and spatial dynamics of signaling and appropriate cellular responses. Discovering new aspects of PAR signaling is important for increasing the fundamental knowledge of GPCR biology and for the identification of drug targets and future drug development. Dr. Trejo’s research has focused on PAR1, which has important functions in hemostasis, thrombosis, inflammation, and cancer and is an important drug target. She has made numerous important discoveries related to the mechanisms that control PAR1 signaling and closely related family members and published extensively on this topic. Dr. Trejo has been continuously funded by the NIH for >20 years and was a recipient of the prestigious American Heart Association Established Investigator Award. Her laboratory is the recognized expert on protease-activated receptors, particularly PAR1, and over the years she has discovered novel aspects of GPCR biology, acquired critical expertise, and rigorous approaches to examine PAR1 function using human cultured cells and mouse models. Dr. Trejo has presented her studies at 52 national/international meetings and 66 academic seminars across the U.S.

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

-------------------------------------------

Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

-   Watch recorded #DRGPCR Virtual Cafe presentations:

https://www.youtube.com/channel/UCJvKL3smMEEXBulKdgT_yCw

-   Bring in a #GPCR Consultant

http://www.drgpcr.com/consulting/

- &

For more details, visit the #DrGPCR Podcast Episode #69 page

http://www.drgpcr.com/episode-69-history-of-the-gpcr-retreat-with-dr-stephen-ferguson/

-------------------------------------------

About Dr. Stephen Ferguson

Dr. Stephen Ferguson is a Professor in the Department of Cellular and Molecular Medicine at the University of Ottawa. He did B.Sc. in biology at McGill University and received his Ph.D. under the mentorship of Dr. Brian Collier in the Department of Pharmacology and Therapeutics at McGill University (1994).

He did his postdoctoral training with Dr. Marc G. Caron at Duke University (1994-1997), where he and his colleagues investigated the role of G protein-coupled receptor kinases and beta-arrestin in regulating G protein-coupled receptor endocytosis, trafficking, and signaling. He has held four Canada Research Chairs since 2001 and was previously a Heart and Stroke Foundation of Canada MacDonald Scholar (1998-2003) and Heart and Stroke Foundation of Ontario Career Investigator (2003-2016).

He was a recipient of Canada's Top 40 under 40 award in 2004 and received Queen Elizabeth II, Diamond Jubilee Medal, in 2012. He has also received both Junior (2001) and Senior (2005) investigator awards from the Pharmacological Society of Canada. Most recently, in 2021, he was elected as a Fellow of the Canadian Academy of Health Science (FCAHS). His research career has focused on the investigation of the regulation of G protein-coupled receptors signaling mechanisms in health and disease. He currently holds multiple research grants from the Canadian Institutes of Health Research (CIHR) for his research investigating the role of metabotropic glutamate receptor signaling in Huntington’s and Alzheimer’s disease.

-------------------------------------------

Dr. Stephen Ferguson on the web

• Carlton University
• Canada Research Chairs
• Twitter
• ResearchGate
• LinkedIn

-------------------------------------------

Great Lakes GPCR Retreat on the web

• 21st Great Lakes GPCR Retreat
• More about previous GPCR Retreat meetings

-------------------------------------------

We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

Fill out the Ecosystem waitlist form today to be the first to explore our brand new and improved space!

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

''Brian Arey is Senior Director of Mechanistic Pharmacology within Leads Discovery and Optimization at Bristol-Myers, Squibb Co. in Lawrenceville, NJ. He obtained both his MS and Ph.D. in Neuroendocrine Physiology at Florida State University before completing his postdoctoral training at Northwestern University. He then moved to work in the pharmaceutical industry where he has held positions of increasing responsibility. He currently leads a team that provides mechanistic understanding of small molecule drug candidates across the entire portfolio of BMS. Brian has contributed to the discovery or development of 5 marketed drugs through his work spanning molecular, biochemical, cellular, and in vivo assessment of drug candidates in many different physiological systems.

Dr. Arey’s laboratory discovered the first described synthetic agonists and antagonists of the FSHR and has been an early champion of signaling bias as a physiological mechanism of gonadotropin action. He continues to pioneer in drug discovery studying GPCRs and other target classes. His recently published book on signaling bias, Biased Signaling in Physiology, Pharmacology, and Therapeutics is available on Amazon.

I sat down with Brian to chat about GPCRs, working in industry, and being a leader. This is part 2 of our conversation.''

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

-   Watch recorded #DRGPCR Virtual Cafe presentations:

https://www.youtube.com/channel/UCJvKL3smMEEXBulKdgT_yCw

-   Bring in a #GPCR Consultant

http://www.drgpcr.com/consulting/

-   Share your feedback with us:

http://www.drgpcr.com/audience-survey/

-   Become a #DrGPCR Ecosystem Member

http://www.drgpcr.com/membership/

Watch the video version of this podcast episode 

-------------------------------------------

Become a #DrGPCR Ecosystem Member 

-------------------------------------------

For more details, visit the #DrGPCR Podcast Episode #90 page

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• Individuals
• Organizations

-------------------------------------------

Are you a #GPCR professional?

• Subscribe to #DrGPCR Monthly Newsletter
• Listen and subscribe to #DrGPCR Podcasts
• Listen and watch GPCR focused scientific talks at #VirtualCafe

⁠Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠

-------------------------------------------

⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠.

⁠Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

⁠⁠⁠⁠⁠⁠⁠Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

⁠Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

Watch the video version of this podcast episode

-------------------------------------------

Become a #DrGPCR Ecosystem Member 

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• Individuals
• Organizations

-------------------------------------------

Are you a #GPCR professional?

• Subscribe to #DrGPCR Monthly Newsletter
• Listen and subscribe to #DrGPCR Podcasts
• Listen and watch GPCR-focused scientific talks at #VirtualCafe.

⁠⁠⁠⁠Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

Watch the video version of this podcast episode.⁠⁠⁠⁠

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⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠Individuals⁠⁠⁠⁠
• ⁠⁠⁠⁠Organizations⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠
• ⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠
• ⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠.

Dr. Bender completed his undergraduate studies at Colgate University in upstate New York with a degree in Biochemistry. Between undergraduate and graduate school Brian worked as a technician in an academic lab before moving to Nashville, TN for graduate work at Vanderbilt University where he joined the Department of Pharmacology. Brain’s work there primarily focused on structure prediction of GPCRs from sparse experimental data. He then moved to the University of California in San Francisco to continue his training as a postdoctoral researcher where he used structural models of GPCRs to virtually screen large compound libraries with the goal of finding new chemical matter to probe understudied and orphan receptors.

Brian is involved in organizing the GRC/GRS Molecular Pharmacology meeting, which has been postponed to 2023. Brian is one of the organizers of the upcoming Transatlantic ECI GPCR Symposium.

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Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

-   Watch recorded #DRGPCR Virtual Cafe presentations:

https://www.youtube.com/channel/UCJvKL3smMEEXBulKdgT_yCw

-   Bring in a #GPCR Consultant

http://www.drgpcr.com/consulting/

-   Share your feedback with us:

http://www.drgpcr.com/audience-survey/

-   Become a #DrGPCR Ecosystem Member

http://www.drgpcr.com/membership/

Watch the video version of this podcast episode.⁠⁠⁠⁠

-------------------------------------------

⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠Individuals⁠⁠⁠⁠
• ⁠⁠⁠⁠Organizations⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠
• ⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠
• ⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠.

Watch the video version of this podcast episode 

------------------------------------------- 

Become a #DrGPCR Ecosystem Member 

-------------------------------------------

For more details, visit the #DrGPCR Podcast Episode #87 page

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• Individuals
• Organizations

-------------------------------------------

Are you a #GPCR professional?

• Subscribe to #DrGPCR Monthly Newsletter
• Listen and subscribe to #DrGPCR Podcasts
• Listen and watch GPCR focused scientific talks at #VirtualCafe

Watch the video version of this podcast episode.⁠⁠⁠

-------------------------------------------

⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠Individuals⁠⁠⁠
• ⁠⁠⁠Organizations⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠
• ⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠
• ⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠.

⁠⁠⁠⁠⁠⁠⁠Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

Watch the video version of this podcast episode.

-------------------------------------------

Become a #DrGPCR Ecosystem Member 

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• Individuals
• Organizations

-------------------------------------------

Are you a #GPCR professional?

• Subscribe to #DrGPCR Monthly Newsletter
• Listen and subscribe to #DrGPCR Podcasts
• Listen and watch GPCR-focused scientific talks at #VirtualCafe.

⁠Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠

-------------------------------------------

⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

⁠Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

To read the full #DrGPCRNewsletter, click here:  

https://www.ecosystem.drgpcr.com/dr-gpcr-newsletter

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Read #ClassifiedGPCRNews here:  

https://www.ecosystem.drgpcr.com/classified-gpcr-news

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Follow #GPCRNews to get the weekly report in your inbox:  

https://www.ecosystem.drgpcr.com/profile/gpcr-news/profile 

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How can Users benefit Dr. GPCR Ecosystem? 

https://www.ecosystem.drgpcr.com/explore-individuals

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How can Organizations benefit from Dr. GPCR Ecosystem? 

https://www.ecosystem.drgpcr.com/explore-organizations

----- 

Become a #DrGPCR Ecosystem Member 

https://www.ecosystem.drgpcr.com/plans-pricing

For more details, visit #DrGPCR Podcast Episode #61 page

https://www.drgpcr.com/episode-61-with-dr-marta-filizola/

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About Dr. Marta Filizola

Dr. Marta Filizola is the Sharon & Frederick A. Klingenstein-Nathan G. Kase, MD Professor in the Departments of Pharmacological Sciences, Neuroscience, and Artificial Intelligence and Human Health, as well as the Dean of The Graduate School of Biomedical Sciences at the Icahn School of Medicine at Mount Sinai, in New York, USA. The overall goal of her research program is to obtain rigorous mechanistic insights into the structure, dynamics, and function of important classes of membrane proteins and prominent drug targets, including G protein-coupled receptors (GPCRs), transporters, channels, and 3 integrins. To this end, her lab uses several computational structural biology tools and rational drug design approaches, ranging from molecular modeling, bioinformatics, cheminformatics, molecular dynamics simulations, free-energy perturbations, machine learning, etc. A native of Italy, she received her Bachelor’s and Master’s degrees in Chemistry from the University Federico II in Naples. She pursued a Ph.D. in Computational Chemistry at the Second University of Naples and a postdoctorate in Computational Biophysics at the Molecular Research Institute in California, USA.

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

-------------------------------------------

Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

-   Watch recorded #DRGPCR Virtual Cafe presentations:

https://www.youtube.com/channel/UCJvKL3smMEEXBulKdgT_yCw

- Bring in a #GPCR Consultant

http://www.drgpcr.com/consulting/

-   Share your feedback with us:

http://www.drgpcr.com/audience-survey/

-   Become a #DrGPCR Ecosystem Member

http://www.drgpcr.com/membership/

⁠⁠⁠⁠⁠⁠⁠Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

About Dr. Nyla Naim

Nyla is a Senior Scientist on the Scientific Support Team at Addgene. She received her Ph.D. at the University of Pittsburgh and continued her postdoctoral research at the University of Vermont studying cellular signaling, biosensors, and optogenetics. Nyla supports biomedical research by connecting researchers with resources and promoting reproducible science.

About Dr. Michael Lemieux

''My name is Michael (Mike) Lemieux and I am a Connecticut native. I completed my Ph.D. in molecular and cell biology at UConn and then joined Addgene as a Quality Control Scientist in 2015. Since then I transitioned into a Scientific Support role to leverage my passion for helping people! Beyond my interest in science, I am a strong advocate for graduate education reform and I love to write.''

About Dr. Jason Nasse

Dr. Jason Nasse is a senior scientist at Addgene specializing in the use of AAV viral vectors. He obtained his Ph.D. in Neuroscience from Ohio State University focusing on synaptic plasticity and adrenergic receptor modulation of both pre-and postsynaptic properties. By taking a very non-traditional path to obtain a Ph.D. Dr. Nasse has had the opportunity to experience how science is performed across different sectors and around the country. Prior to his role at Addgene, Jason held roles in academia, big pharma, and non-profit research organizations.

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

-   Watch recorded #DRGPCR Virtual Cafe presentations:

https://www.yo&a

For more details, visit the #DrGPCR Podcast Episode #80 page

https://www.drgpcr.com/episode-80-with-andrew-tobin/

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About Dr. Andrew Tobin

Andrew Tobin studied Biochemistry at Queen Mary College, the University of London obtaining first-class honors before studying for a D.Phil at the University of Oxford. Following a post-doctoral period at Bristol Myers Squibb in Princeton USA, Andrew returned to the UK to establish his own laboratory at the University of Leicester. Funded through three consecutive Wellcome Trust Senior Research Fellowships Andrew established a reputation in the field of receptor signaling.

Now at the University of Glasgow, his primary research interests are focused on the rational design of novel drugs to treat the three global health challenges of dementia, asthma, and malaria. In this Andrew runs a research laboratory of around 15 staff supported by basic research grants investigating aspects of disease biology and the action of drugs in the context of disease. The vehicle by which Andrew is translating fundamental findings to commercial products is Keltic Pharma Therapeutics Ltd, a biotechnology company co-founded by Andrew with series A funding from the European Union.

Andrew is also the Director of the Advanced Research Centre (ARC) a collaborative initiative at the University of Glasgow underpinned by a £118M new build that will house over 550 researchers designed to drive interdisciplinary research.

Dr. Andrew Tobin on the web

• University of Glasgow 
• ResearchGate
• Google Scholar
• Twitter
• Dr. GPCR Ecosystem

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Become a #DrGPCR Ecosystem Member

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

• Individuals
• Organizations

-------------------------------------------

Are you a #GPCR professional?

• Subscribe to #DrGPCR Monthly Newsletter
• Listen and subscribe to #DrGPCR Podcasts
• Listen and watch GPCR focused scientific talks at #VirtualCafe

Michel Bouvier is a professor of Biochemistry and Molecular Medicine and the CEO of the Institute for Research in Immunology and Cancer (IRIC) at the Université de Montréal.

Following his Ph.D. in Neurological Sciences at the same university in 1985, he completed a post-doctoral fellow at Duke University in the laboratory of R.R. Lefkowitz. In 1989, he returned to Montréal as a professor of biochemistry and a scholar of the Medical Research Council of Canada at the Faculty of Medicine of the Université de Montréal.

Since 2001, he holds the Canada Research Chair in Signal Transduction and Molecular Pharmacology. Dr. Bouvier is the author of 300 scientific papers and 15 patents and delivered close to 500 invited conferences. He is a world-renowned expert in the field of cell signaling and GPCRs and made seminal contributions to our understanding of this major class of drug targets. In addition to paradigm shifts including inverse agonism, biased signaling, and pharmacological chaperones, his work on bioluminescence resonance energy transfer (BRET) resulted in the development of screening assays that are now widely used for drug discovery.

His work received more than 30,000 citations yielding an h-index of 95. He has supervised the research work of 75 graduate students and 40 post-doctoral fellows. Michel’s scientific contributions were recognized by the attribution of many awards and distinctions including his election as a fellow of the Royal Society of Canada (2014), the Julie Axelrod award from the American Society of Pharmacology and Exerimental Therapeutics (2017), the Wilder Penfield award from the Quebec Government (2017), the innovation award of ADRIQ (2019) and the 2021 Killam prize form the Canada Council for the Arts.

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

-   Watch recorded #DRGPCR Virtual Cafe presentations:

https://www.youtube.com/channel/UCJvKL3smMEEXBulKdgT_yCw

-   Bring in a #GPCR Consultant

http://www.drgpcr.com/consulting/

-   Share your feedback with us:

http://www.drgpcr.com/audience-survey/

-   Become a #DrGPCR Ecosystem Member

http://www.drgpcr.com/membership/

For more details, visit #DrGPCR Podcast Episode #67 page

https://www.drgpcr.com/episode-67-with-graham-ladds/

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About Dr. Graham Ladds

Graham studied Biochemistry at the University of Birmingham before completing a Ph.D. in yeast pheromone signaling at Warwick. He continued to work at Warwick as a post-doc studying pro-hormone convertases before securing a 5-year independent fellowship funded through the NHS. This project enabled him to return to his interest in GPCRs.

He progressed through the ranks at Warwick to become an Associate Professor before leaving in 2015 to join the Department of Pharmacology at Cambridge, where he is also a Fellow of St John’s College. In 2020, he was promoted to a Readership/Professor in Receptor Pharmacology and was elected a Fellow of the British Pharmacological Society.

His research group uses a combination of pharmacological investigations and mathematical modeling to study factors that control agonist bias at GPCRs. These investigations have enabled him to foster strong collaborations with the pharmaceutical industry (GSK, Takada, and Firmenich) which have recently been enhanced through him being awarded a Royal Society Industry Fellowship to collaborate with AstraZeneca.

Dr. Graham Ladds on the web

• Twitter
• ResearchGate
• LinkedIn
• Google Scholar
• PubMed

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We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

Fill out the Ecosystem waitlist form today to be the first to explore our brand new and improved space!

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

-------------------------------------------

Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

-   Watch recorded #DRGPCR Virtual Cafe presentations:

https://www.youtube.com/channel/UCJvKL3smMEEXBulKdgT_yCw

-   Share your feedback with us:

http://www.drgpcr.com/audience-survey/

For more details, visit #DrGPCR Podcast Episode #60 page

https://www.drgpcr.com/episode-60-with-dr-josephine-pina-cardarelli/

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About Dr. Josephine (Pina) Cardarelli  

Dr. Pina Cardarelli, CSO for GPCR Therapeutics Inc., based in South Korea, has recently been named President of GPCR Therapeutics, USA, a newly incorporated Biotechnology company in the Bay Area. The company’s mission is to discover and develop highly effective cancer therapeutics by targeting heteromers of G protein-coupled receptors (GPCR). Burixafor, their most advanced clinical candidate, will be in Phase II clinical trial next year. Additionally, they have a library of target GPCR heteromers for Oncology. Dr. Cardarelli heads the team of talented researchers that will be expanding at the US site.  

Dr. Cardarelli is a drug development leader with extensive experience driving drug discovery teams in bringing biologics to clinical proof of concepts. She has expertise in cell biology, pharmacology, translational medicine, oncology, immuno-oncology, immunology, and clinical development. Previously, she held the position of Vice President of Cell Biology & Pharmacology, at Bristol-Myers Squibb. She was an integral contributor to two therapeutics that are FDA approved, Yervoy and Opdivo. She was a participant in numerous due diligence (anti-CXCL8 mAb) and has managed external collaborations and alliances. Prior to this, she held the position of Vice President, at Medarex, Inc. While at BMS and Medarex, she led programs from target ID to clinical development that included, CXCL10 (Eldelumab), CXCR4 (Ulocuplumab), CD30, CD19, Fucosyl GM-1, & mesothelin-ADC, Glypican-3-ADC, CD70-ADC.

She oversaw early discovery programs IL-23 p19 and IL23 p19/IL-17 bispecifics. At Medarex, she initiated and identified the lead mAb for the type I interferon-alpha receptor project, licensed to AstraZeneca (Saphnelo™ Anifrolumab) that has just received FDA approval for systemic lupus erythematosus. She has extensive experience working with Biologics, and Antibody Drug Conjugates as well as experience in IND fillings, IB updates, and responding to FDA inquiries. She is an inventor on 39 issued U.S. patents including anti-PD-1 patents, 22 EP patents, and greater than 100 global patents centered around therapeutic development. She has also authored forty-six peer-reviewed publications. Dr. Cardarelli received her Ph.D. in Physiology from Albany Medical College.     

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Dr. Josephine (Pina) Cardarelli on the web

LinkedIn 

https://www.linkedin.com/in/josephine-pina-cardarelli/

Website  

http://gpcr.co.kr/

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Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

-------------------------------------------

Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

⁠⁠⁠⁠⁠⁠Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

For more details, visit #DrGPCRPodcast Episode #58 page

https://www.drgpcr.com/episode-58-with-juan-jose-fung/

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About Dr. Juan José Fung

Dr. Juan José Fung is a Principal Scientist at GPCR Therapeutics, Inc, a drug discovery company focused on targeting GPCR heteromers in cancer, headquartered in Seoul, Korea, with an R&D facility in the SF Bay Area. Dr. Fung received his Ph.D. from the Stanford University School of Medicine under the mentorship of Dr. Brian Kobilka, studying the dimerization of GPCRs. Dr. Fung continued his Postdoctoral training in Dr. Kobilka’s lab contributing to the elucidation of high-resolution structures of various GPCRs. Dr. Fung has spent significant time in the industry studying membrane proteins, antibodies, and HTS methods for drug discovery. His current work is mainly focused on screening and assay development to bridge the gap between in vitro and in vivo GPCR pharmacology.

Dr. Juan José Fung on the web

• LinkedIn
• Website

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

-------------------------------------------

Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

-   Watch recorded #DRGPCR Virtual Cafe presentations:

https://www.youtube.com/channel/UCJvKL3smMEEXBulKdgT_yCw

-   Bring in a #GPCR Consultant

http://www.drgpcr.com/consulting/

Watch the video version of this podcast episode.⁠

-------------------------------------------

⁠Become a #DrGPCR Ecosystem Member ⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠Individuals⁠
• ⁠Organizations⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠Subscribe to #DrGPCR Monthly Newsletter⁠
• ⁠Listen and subscribe to #DrGPCR Podcasts⁠
• ⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠.

⁠Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠

-------------------------------------------

⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

Dr. Terry Hebert wanted to be a microbiologist. Instead, he ended up getting interested in membrane protein as he followed the biology of a bacterial toxin that affects a mammalian ion channel. Today he and his team are working on understanding receptor signaling in specialized cellular environments to gain a better grasp of receptor function in pathophysiological settings with a special interest in the cardiovascular system. His favorite GPCR is the angiotensin 1 receptor especially for its ability to activate a large variety of signaling pathways. Terry is also very active on social media. With over 2000 followers on Facebook and Twitter, he shares the latest available information on GPCR research daily.

⁠Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

Dr. Debbie Hay is presently a professor at the Department of Pharmacology and Toxicology at the University of Otago after spending 18 years at the University of Auckland. Her work is primarily focused on class B GPCRs and their interactions with RAMPs. Debbie obtained a Ph.D. in Molecular Pharmacology from Imperial College London in the UK. She has gained experience from working in academia and at GSK as an industrial trainee.

Join me and learn more about Debbie’s career and what she learned through her experiences as a scientist.

⁠Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

Undergraduate BSc with Honours in Pharmacology from University of Sydney (1987, snake neurotoxins), Ph.D. from Department of Pharmacology, University of Washington (1992, mentor Charley Chavkin, sigma receptors). Postdoc with Graeme Henderson (Bristol, opioids and Ca signaling) and Mac Christie (Sydney, opioids in neurons, novel spider toxins). Grant-funded independent research positions from 2001 at University of Sydney (opioids and sensory neurons), Vollum Institute Portland (visiting scientist with Ed McCleskey, sensory neuron properties); Pain Management Research Institute (more opioids, cannabinoids and T-type Ca channels) and Brain and Mind Research Institute (Sydney). 2009, appointed Professor of Pharmacology at Macquarie University. Focus on study of drugs and toxins on GPCR (opioid, cannabinoid receptor) and ion channel (K, Ca, TRP channel) function; mostly electrophysiology and fluorescence-based reporters, but can grind and bind. Currently pursuing molecular pharmacology of phytocannabinoids and novel synthetic cannabinoids, with a focus on efficacy and novel targets. Interested in orthosteric and allosteric interactions, and still looking for some bias ... anywhere ... these days human only.

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

-------------------------------------------

Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

-   Watch recorded #DRGPCR Virtual Cafe presentations:

https://www.youtube.com/channel/UCJvKL3smMEEXBulKdgT_yCw

-   Bring in a #GPCR Consultant

http://www.drgpcr.com/consulting/

-   Share your feedback with us:

http://www.drgpcr.com/audience-survey/

-   Become a #DrGPCR Ecosystem Member

http://www.drgpcr.com/membership/

Brian Arey is Senior Director of Mechanistic Pharmacology within Leads Discovery and Optimization at Bristol-Myers, Squibb Co. in Lawrenceville, NJ. He obtained both his MS and Ph.D. in Neuroendocrine Physiology at Florida State University before completing his postdoctoral training at Northwestern University. He then moved to work in the pharmaceutical industry where he has held positions of increasing responsibility. He currently leads a team that provides a mechanistic understanding of small molecule drug candidates across the entire portfolio of BMS. Brian has contributed to the discovery or development of 5 marketed drugs through his work spanning molecular, biochemical, cellular, and in vivo assessment of drug candidates in many different physiological systems.

Dr. Arey’s laboratory discovered the first described synthetic agonists and antagonists of the FSHR and has been an early champion of signaling bias as a physiological mechanism of gonadotropin action. He continues to pioneer in drug discovery studying GPCRs and other target classes. His recently published book on signaling bias, Biased Signaling in Physiology, Pharmacology, and Therapeutics is available on Amazon.

I sat down with Brian to chat about GPCRs, working in the industry, and being a leader. This is part 1 of our conversation.

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Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

-   Watch recorded #DRGPCR Virtual Cafe presentations:

https://www.youtube.com/channel/UCJvKL3smMEEXBulKdgT_yCw

-   Bring in a #GPCR Consultant

http://www.drgpcr.com/consulting/

-   Share your feedback with us:

http://www.drgpcr.com/audience-survey/

-   Become a #DrGPCR Ecosystem Member

http://www.drgpcr.com/membership/

Watch the video version of this podcast episode 

------------------------------------------- 

Become a #DrGPCR Ecosystem Member 

-------------------------------------------

For more details, visit the #DrGPCR Podcast Episode #82 page

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• Individuals
• Organizations

-------------------------------------------

Are you a #GPCR professional?

• Subscribe to #DrGPCR Monthly Newsletter
• Listen and subscribe to #DrGPCR Podcasts
• Listen and watch GPCR focused scientific talks at #VirtualCafe

For more details, visit the #DrGPCR Podcast Episode #73 page

https://www.drgpcr.com/episode-73-with-dr-aylin-hanyaloglu/

-------------------------------------------

About Dr. Aylin Hanyaloglu

Dr. Aylin Hanyaloglu has been a Principal Investigator at Imperial College London since 2007. She received her BSc in Human Biology from King’s College London in 1997, and while her Ph.D. commenced at the MRC Human Reproductive Sciences Centre, Edinburgh, a move to Perth, Australia resulted in her Ph.D. in Molecular Endocrinology being awarded in 2002 with Distinction from the University of Western Australia.

Dr. Hanyaloglu undertook her postdoctoral training at the University of California, San Francisco with Professor Mark von Zastrow where she identified novel core cellular machinery critical for G protein-coupled receptor trafficking and signaling.

Her research focuses on understanding the fundamental cell biological mechanisms regulating GPCR activity, including spatial control of GPCR signaling and receptor crosstalk, and applying these mechanisms for distinct GPCRs in diverse physiological and pathophysiological systems, with particular focus on women's health, pregnancy, and nutrient sensing in the gut. Her work is currently funded by Biotechnology and Biological Sciences Research Council (BBSRC), Diabetes UK, Wellcome Trust, and the Medical Research Council.

Dr. Aylin Hanyaloglu on the web

• LinkedIn
• Researchgate
• Twitter
• Imperial College London
• Elsevier
• Loop

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We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

Fill out the Ecosystem waitlist form today to be the first to explore our brand new and improved space!

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

-------------------------------------------

Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

-   Watch recorded #DRGPCR Virtual Cafe presentations:

https://www.youtube.com/channel/UCJvKL3smMEEXBulKdgT_yCw

-   Share your feedback with us:

http://www.drgpcr.com/audience-survey/

For more details, visit #DrGPCR Podcast Episode #63 page

https://www.drgpcr.com/episode-63-with-dr-khaled-abdelrahman/

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Dr. Khaled Abdelrahman graduated in 2006 with a BSc in Pharmaceutical Sciences from Alexandria University (Egypt) followed by MSc in Pharmacology in the same university that was conferred in 2009. He joined the laboratory of Dr. William Cole at the University of Calgary in 2010 for his Ph.D. where he studied the molecular basis underlying altered cerebrovascular function and blood flow in type 2 diabetes. In 2015, He joined Dr. Stephen Ferguson’s laboratory in the Departments of Cellular & Molecular Medicine and Neuroscience at the University of Ottawa as a Postdoctoral Fellow to explore novel G protein-coupled receptor (GPCR) candidates that can be targeted pharmacologically to slow neurodegeneration. He has been also studying what aspects of GPCR signaling are regulated in a sex-selective manner and how this can influence drug discovery in the area of neurodegenerative diseases.

He is also a Registered Pharmacist in Canada and held two of the most prestigious Clinician Postdoctoral Fellowships offered by Alberta Innovates and Canadian Institutes of Health Research. He received the Canadian Society of Pharmacology and Therapeutics Postdoctoral and Publication awards along with many Young Scientist Awards from the American Society for Pharmacology and Experimental Therapeutics.

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

-------------------------------------------

Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

-   Watch recorded #DRGPCR Virtual Cafe presentations:

https://www.youtube.com/channel/UCJvKL3smMEEXBulKdgT_yCw

- Bring in a #GPCR Consultant

http://www.drgpcr.com/consulting/

-   Share your feedback with us:

http://www.drgpcr.com/audience-survey/

-   Become a #DrGPCR Ecosystem Member

http://www.drgpcr.com/membership/

⁠⁠⁠⁠⁠⁠⁠Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠.

For more details, visit #DrGPCR Podcast Episode #68 page

https://www.drgpcr.com/episode-68-with-dr-matthew-eddy/

-------------------------------------------

About Dr. Matthew Eddy

Matthew Eddy earned his BA in Chemistry from Oberlin College, where he trained with solid-state NMR expert Professor Manish Mehta. He then earned his Ph.D. in physical chemistry from the Massachusetts Institute of Technology, training under the mentorship of Prof. Robert Griffin. Following this, Dr. Eddy began learning and investigating human GPCRs while training in the laboratories of Professors Raymond Stevens and Kurt Wüthrich at The Scripps Research Institute.

Dr. Matthew Eddy on the web

• Website

-------------------------------------------

We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

Fill out the Ecosystem waitlist form today to be the first to explore our brand new and improved space!

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

-------------------------------------------

Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

-   Watch recorded #DRGPCR Virtual Cafe presentations:

https://www.youtube.com/channel/UCJvKL3smMEEXBulKdgT_yCw

-   Share your feedback with us:

http://www.drgpcr.com/audience-survey/

For more details, visit #DrGPCR​​​ Podcast Episode #56 page:

http://www.drgpcr.com/episode-56-with-dr-adriano-marchese/

-------------------------------------------

Adriano Marchese is a Professor of Biochemistry at the Medical College of Wisconsin. Adriano received his Bachelor of Science degree in Pharmacology in 1991 from the University of Toronto. He continued his graduate studies at the University of Toronto where he earned his MSc (1994) and Ph.D. (1998) in Pharmacology. He then moved to Thomas Jefferson University in Philadelphia, PA, for his postdoctoral training in Jeff Benovic’s laboratory studying the regulation of G protein-coupled receptor trafficking and signaling. In 2004 Adriano joined the faculty of the Department of Pharmacology at Loyola University Chicago. In 2016 he decided to move his lab to the Medical College of Wisconsin in Milwaukee, WI.

Adriano’s research has contributed to our understanding of the role that ubiquitin plays in GPCR signaling and trafficking. His laboratory is interested in understanding the mechanisms that govern spatial and temporal regulation of GPCR signaling by -arrestins and post-translational modifications (PTMs), such as phosphorylation, ubiquitination, and SUMOylation. His lab has shown a role for -arrestins and PTMs in GPCR trafficking and signaling and has leveraged this knowledge to reveal the spatial and temporal requirements for GPCR activation of signaling pathways related to cell survival, proliferation, and migration. The ultimate goal of Adriano’s research is to target novel aspects of GPCR signaling for therapeutic development.

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

For more details, visit our website http://www.DrGPCR.com/Ecosystem/

-------------------------------------------

Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

⁠Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠

-------------------------------------------

⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

''Dr. Ross Cheloha is an Investigator at the National Institutes of Health in the Laboratory of Bioorganic Chemistry in Bethesda, MD, where he started in October 2020. He completed his postdoctoral training at MIT and Harvard Med School in the lab of Hidde Ploegh where he developed new applications of single domain antibodies (nanobodies). He earned his PhD in Chemistry at the University of Wisconsin-Madison in the lab of Sam Gellman on the study of analogs of the GPCR peptide ligand parathyroid hormone. Work in his independent laboratory is focused on developing new pharmacological tools via chemistry and protein engineering to interrogate GPCR signaling.

Ross and I chatted about his work and his transition to an independent investigator, Join me to learn more about class B GPCRs and Dr. Cheloha’s work.''

Watch the video version of this podcast episode 

-------------------------------------------

Become a #DrGPCR Ecosystem Member 

-------------------------------------------

For more details, visit the #DrGPCR Podcast Episode #90 page

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• Individuals
• Organizations

-------------------------------------------

Are you a #GPCR professional?

• Subscribe to #DrGPCR Monthly Newsletter
• Listen and subscribe to #DrGPCR Podcasts
• Listen and watch GPCR focused scientific talks at #VirtualCafe

Sam completed his Ph.D. in biochemistry, studying allosteric modulation of dopamine receptors, from the University of Kent, United Kingdom. He then moved to the National Institute of Mental Health, researching pharmacological mechanisms of Class B GPCRs as part of his postdoctoral training.

Today, Sam is a pharmacology data analyst and the founder of Pharmechanics LLC, a consultancy and data analysis company supporting pharmaceutical, life science, and academic scientists in the development of new therapeutics and the understanding of receptor systems. As an industry pharmacologist, he consults with numerous pharma and biotechs in understanding and applying in vitro pharmacology data to advance drug discovery. He specializes in kinetic analysis of drug action and is known for applying binding kinetics to the development of effective therapeutics, particularly GPCR antagonists.

Before founding Pharmechanics in 2016, Dr. Hoare was a pharmacology leader in the pharmaceutical industry for 15 years at Neurocrine Biosciences. He guided the in vitro biology efforts of the company for numerous drug discovery campaigns. Sam is known for demystifying complicated and newly-emerging pharmacology concepts, enabling them to be applied by project teams in optimizing new molecules.

I very much enjoyed chatting with Sam about his love for GPCRs, kinetics, and decorticate the complexities of GPCR function to better target receptors.

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

-   Watch recorded #DRGPCR Virtual Cafe presentations:

https://www.youtube.com/channel/UCJvKL3smMEEXBulKdgT_yCw

-   Bring in a #GPCR Consultant

http://www.drgpcr.com/consulting/

-   Share your feedback with us:

http://www.drgpcr.com/audience-survey/

-   Become a #DrGPCR Ecosystem Member

http://www.drgpcr.com/membership/

Watch the video version of this podcast episode.⁠

-------------------------------------------

⁠Become a #DrGPCR Ecosystem Member ⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠Individuals⁠
• ⁠Organizations⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠Subscribe to #DrGPCR Monthly Newsletter⁠
• ⁠Listen and subscribe to #DrGPCR Podcasts⁠
• ⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠.

Watch the video version of this podcast episode 

------------------------------------------- 

Become a #DrGPCR Ecosystem Member 

-------------------------------------------

For more details, visit the #DrGPCR Podcast Episode #88 page

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• Individuals
• Organizations

-------------------------------------------

Are you a #GPCR professional?

• Subscribe to #DrGPCR Monthly Newsletter
• Listen and subscribe to #DrGPCR Podcasts
• Listen and watch GPCR focused scientific talks at #VirtualCafe

⁠Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

To read the full #Newsletter click here:

http://www.drgpcr.com/february-2022/

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

⁠Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠

-------------------------------------------

⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

⁠Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

Watch the video version of this podcast episode.

https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-160-with-dr.-remi-janicot

---------------------------------

Become a #DrGPCR Ecosystem Member

---------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

---------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• Individuals
• Organizations

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

⁠⁠⁠⁠⁠⁠⁠Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

In this science-focused episode of the Dr. GPCR podcast, we meet Dr. Ian Chronis, a freshly minted PhD from the University of Michigan. While his academic roots started in classical history and ancient Greek, Ian’s curiosity pulled him toward chemistry, then pharmacology, and eventually into the complex world of GPCR signaling. His story is a testament to the power of staying open to change and following emerging scientific questions wherever they lead.

Ian’s doctoral work focused on two key GPCR systems: the well-characterized β2-adrenergic receptor and the lesser-known proton-sensing receptor GPR65. In the former, he explored how PKA phosphorylation modulates receptor interactions and discovered a regulatory role for 14-3-3 proteins. But it’s GPR65 — a receptor that constitutively internalizes and signals from acidic endosomes — that has captured Ian’s attention and become the centerpiece of his current research. Unlike classical GPCRs, GPR65 uses non-canonical internalization mechanisms, presenting new opportunities to uncover novel biology.

The receptor’s ability to signal within the tumor microenvironment and immune cells makes it an emerging drug target, especially in cancer immunotherapy. However, there are still major gaps: no selective ligands, little clarity on its internalization machinery, and limited tools to modulate its function. Ian’s wish list? A high-affinity agonist and antagonist to begin untangling these questions. Until then, he's carefully optimizing pH-based assays and preparing for next steps in a postdoctoral lab focused on more physiological and therapeutic systems.

Whether he’s decoding novel trafficking pathways or reflecting on career strategy, Ian brings a balanced perspective that’s both ambitious and grounded. His advice to peers? Attend talks outside your field, learn constantly, and surround yourself with people who make science sustainable. This episode is a must-listen for those navigating the intersection of curiosity, technical rigor, and translational potential in the GPCR research community.

Watch the video version of this podcast episode:

https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-164-with-dr.-ian-chronis

---------------------------------

Become a #DrGPCR Ecosystem Member

---------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of #GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

---------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• Premium Yearly
• Premium Yearly for Teams
• Developing Countries

Are you a #GPCR professional?

• Subscribe to the Classified GPCR Weekly News
• Listen and subscribe to #DrGPCRPodcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Watch the video version of this podcast episode 

https://www.ecosystem.drgpcr.com/dr-gpcr-podcast

------------------------------------------- 

Learn more about Dr. Graciela Pineyro 

https://www.ecosystem.drgpcr.com/search?q=Graciela+Pineyro

------------------------------------------- 

How Users can benefit Dr. GPCR Ecosystem? 

https://www.ecosystem.drgpcr.com/explore-individuals

------------------------------------------- 

How Organizations can benefit from Dr. GPCR Ecosystem? 

https://www.ecosystem.drgpcr.com/explore-organizations

------------------------------------------- 

Become a #DrGPCR Ecosystem Member 

https://www.ecosystem.drgpcr.com/plans-pricing

-------------------------------------------  

Imagine a world in which the vast majority of us are healthy.  

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.   

To build our #GPCR Ecosystem, we created various enabling outlets.  

- Individuals 

https://www.ecosystem.drgpcr.com/explore-individuals 

- Organizations 

https://www.ecosystem.drgpcr.com/explore-organizations

-------------------------------------------  

Are you a #GPCR professional?   

-   Subscribe to #DrGPCR monthly newsletter 

http://www.drgpcr.com/newsletter/ 

-   Listen and subscribe to #DrGPCR Podcasts  

http://www.drgpcr.com/podcast/ 

-   Listen and watch GPCR focused scientific talks at #VirtualCafe 

https://www.drgpcr.com/virtual-cafe/

⁠Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

To read the full #DrGPCRNewsletter click here: ⁠https://www.ecosystem.drgpcr.com/dr-gpcr-newsletter/24-03-dr-gpcr-newsletter⁠ ------------------------------------------- How can Users benefit Dr. GPCR Ecosystem? ⁠https://www.ecosystem.drgpcr.com/explore-individuals⁠ ------------------------------------------- How can Organizations benefit from Dr. GPCR Ecosystem? ⁠https://www.ecosystem.drgpcr.com/explore-organizations⁠ ------------------------------------------- Become a #DrGPCR Ecosystem Member ⁠https://www.ecosystem.drgpcr.com/plans-pricing⁠ ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. To build our #GPCR Ecosystem, we created various enabling outlets. Individuals ⁠https://www.ecosystem.drgpcr.com/explore-individuals⁠ Organizations ⁠https://www.ecosystem.drgpcr.com/explore-organizations⁠ ------------------------------------------- Are you a #GPCR professional? - Subscribe to #DrGPCR monthly newsletter ⁠http://www.drgpcr.com/newsletter/⁠ - Listen and subscribe to #DrGPCR Podcasts ⁠http://www.drgpcr.com/podcast/⁠ - Listen and watch GPCR-focused scientific talks at #VirtualCafe ⁠https://www.drgpcr.com/virtual-cafe/

⁠Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠

-------------------------------------------

⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

In this Episode 0 of the podcast, I, Dr. Yamina Bechiche, your host, and founder of DrGPCR introduce you to the very first podcast dedicated to GPCR researchers and their work.  This podcast is part of the Dr. GPCR Ecosystem.  The goal is to bring us together GPCR scientists, biotech, and pharma leaders as well as suppliers working on GPCRs. We want to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together to accelerate GPCR drug discovery and improve human health. 

For more information visit us at DrGPCR.com/Podcast and join the DrGPCR Ecosystem at DrGPCR.com/Ecosystem. Don't forget to subscribe to our monthly newsletter at DrGPCR.com/Newsletter.

About Dr. Sudha Shenoy

Dr. Sudha Shenoy is currently an Associate Professor in Medicine & Cell Biology in the Division of Cardiovascular Medicine, Duke University Medical Center. She received her Ph.D. from Oklahoma State University and completed her postdoctoral training with Dr. Robert J. Lefkowitz (Nobel Laureate, 2012) at Duke University. Dr. Shenoy’s postdoctoral research discovered that ubiquitination of mammalian G protein-coupled receptors is a tag for lysosomal degradation, whereas ubiquitination of the adaptor protein, β-arrestin, is a tag for receptor internalization and formation of signaling endosomes. Her laboratory has continued to work on identifying the molecular mechanisms that ascribe ubiquitin code on GPCRs and β-arrestins. Current efforts aim to understand the regulation of GPCR and beta-arrestin signaling in the heart and vascular endothelium by the deubiquitinating enzymes USP20 and USP33.

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

For more details, visit our website http://www.DrGPCR.com/Ecosystem/

-------------------------------------------

Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

Dr. Niv is currently an associate professor and vice dean for research at the Hebrew University of Jerusalem. The Niv lab is also part of the Global Consortium for Chemosensory Research. Masha earned her Bachelor’s degree in chemistry, followed by a direct Ph.D. at the Institute of Chemistry, at The Hebrew University of Jerusalem in Israel. Dr. Niv trained as a postdoctoral fellow at Weill Cornell Medical College. Her work focuses on both sweet and bitter taste receptor GPCRs and her lab established the BitterDB.

⁠Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

⁠⁠⁠⁠⁠⁠⁠Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

Fiona Marshall got fascinated with GPCRs after attending a lecture on how the beta-adrenergic receptor in the heart is activated by adrenaline, during her undergraduate studies at Bath University. She then pursued her Ph.D. in neuroscience from Cambridge University. An expert in GPCR biology, Fiona published the first description of the cloning and structural requirements of the GABAB receptor. One of her career path defining moments came from when she visited Dr. Chris Tate and Dr. Richard Henderson at the Laboratory of Molecular Biology in Cambridge, UK. As a co-founder of Heptares Therapeutics, now called Sosei Heptares, a GPCR focused drug discovery and development biotechnology company, Fiona and her team made considerable breakthroughs in the field of GPCR stabilization and structure-based drug design. Today, Dr. Marshall is the VP Head of Neuroscience Discovery and Head of Discovery UK, Global Head of Neuroscience discovery research leading teams in West Point, Boston, and London at MSD. Join me and learn more about her fascinating career trajectory.

Stuart graduated from the University of Leeds in the U.K. with a First Class Honors degree in Pharmacology. At the end of his studies, he was awarded the Pfizer Prize for undergraduate research. He then completed his Ph.D. at Leeds as well as the University’s Ackroyd, Brotherton, and Brown Scholar.

Following his Ph.D., Dr. Maudsley was awarded a Howard Hughes Medical Institute Fellowship to train with Professor Robert Lefkowitz at Duke University. Following this tremendous experience, he was recruited to be the Principal Investigator of the Receptor Biology Section at the Medical Research Council (MRC) -Human Reproductive Sciences Unit within the University of Edinburgh. At the MRC he developed novel prostate cancer therapeutics based upon his research into GPCR pluridimensional signaling. To broaden his biomedical skill-set Stuart next accepted the position of Head of the Receptor Pharmacology Unit at the National Institutes of Health – National Institute on Aging at the Johns Hopkins University Medical Center. At the NIH he was the recipient of the coveted NIH ‘Bench-to-Bedside’ Translational Research Grant Award, one of the few awards available within the intramural NIH program. Upon starting a new family, and returning to Europe, Dr. Maudsley continued his scientific journey with the award of the highly-valued Odysseus Program Type I Program Grant to work as both the Adjunct Director of the VIB Center for Molecular Neurology and also Vice-Chair of the Department of Biomedical Sciences at the University of Antwerp.

Stuart’s current research, in the Receptor Biology Lab, focuses on the development of novel GPCR-based therapeutics that interdict diseases based on their gerontological underpinnings. This research stream is now forming the basis of a new technology-based start-up company, HeptOME, to help screen and develop novel longevity/disease-regulating compounds with multidimensional disease efficacy profiles.

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

To build our #GPCR Ecosystem, we created various enabling outlets.

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

Are you a #GPCR professional?

- Register to become a Virtual Cafe speaker

http://www.drgpcr.com/virtual-cafe/

-   Subscribe to our Monthly Newsletter

http://www.drgpcr.com/newsletter/

-   Listen and subscribe to #DrGPCR Podcasts

http://www.drgpcr.com/podcast/

-   Support #DrGPCR Ecosystem with your Donation.

http://www.drgpcr.com/sponsors/

-   Reserve your spots for the next #DrGPCR Virtual Cafe

http://www.drgpcr.com/virtual-cafe/

-   Watch recorded #DRGPCR Virtual Cafe presentations:

https://www.youtube.com/channel/UCJvKL3smMEEXBulKdgT_yCw

-   Bring in a #GPCR Consultant

http://www.drgpcr.com/consulting/

-   Share your feedback with us:

http://www.drgpcr.com/audience-survey/

-   Become a #DrGPCR Ecosystem Member

http://www.drgpcr.com/membership/

⁠Watch the video version of this podcast episode.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠

-------------------------------------------

⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Become a #DrGPCR Ecosystem Member ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Imagine a world in which the vast majority of us are healthy.

The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

-------------------------------------------

To build our #GPCR Ecosystem, we created various enabling outlets.

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Individuals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Organizations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

-------------------------------------------

Are you a #GPCR professional?

• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to #DrGPCR Monthly Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and subscribe to #DrGPCR Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠
• ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Listen and watch GPCR-focused scientific talks at #VirtualCafe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

For more details, visit the #DrGPCR Podcast Episode #72 page

https://www.drgpcr.com/episode-72-with-stuart-maudsley/

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About Dr. Stuart Maudsley

Stuart graduated from the University of Leeds in the U.K. with a First Class Honors degree in Pharmacology. At the end of his studies, he was awarded the Pfizer Prize for undergraduate research. He then completed his Ph.D. at Leeds as well as the University’s Ackroyd, Brotherton, and Brown Scholar.

Following his Ph.D., Dr. Maudsley was awarded a Howard Hughes Medical Institute Fellowship to train with Professor Robert Lefkowitz at Duke University. Following this tremendous experience, he was recruited to be the Principal Investigator of the Receptor Biology Section at the Medical Research Council (MRC) -Human Reproductive Sciences Unit within the University of Edinburgh.

At the MRC he developed novel prostate cancer therapeutics based upon his research into GPCR pluridimensional signaling. To broaden his biomedical skill-set Stuart next accepted the position of Head of the Receptor Pharmacology Unit at the National Institutes of Health – National Institute on Aging at the Johns Hopkins University Medical Center. At the NIH he was the recipient of the coveted NIH ‘Bench-to-Bedside’ Translational Research Grant Award, one of the few awards available within the intramural NIH program. Upon starting a new family, and returning to Europe, Dr. Maudsley continued his scientific journey with the award of the highly-valued Odysseus Program Type I Program Grant to work as both the Adjunct Director of the VIB Center for Molecular Neurology and also Vice-Chair of the Department of Biomedical Sciences at the University of Antwerp.

Stuart’s current research, in the Receptor Biology Lab, focuses on the development of novel GPCR-based therapeutics that interdict diseases based on their gerontological underpinnings. This research stream is now forming the basis of a new technology-based start-up company, HeptOME, to help screen and develop novel longevity/disease-regulating compounds with multidimensional disease efficacy profiles.

Dr. Stuart Maudsley on the web

• Maudsley Lab
• LinkedIn
• Google Scholar
• ResearchGate
• Maudsley Lab on Facebook
• Receptor Biology Lab Facebook Group
• Twitter
• Semantic Scholar
• Instagram
• Neurotree
• Dimensions
• Reddit

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We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.

Fill out the Ecosystem waitlist form today to be the first to explore our brand new and improved space!

For more details, visit our website http://www.DrGPCR.com/Ecosystem/.

Watch the video version of this podcast episode 

https://www.ecosystem.drgpcr.com/dr-gpcr-podcast

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Learn more about Dr. Paul Insel 

https://www.ecosystem.drgpcr.com/search?q=paul+insel

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How Users can benefit Dr. GPCR Ecosystem? 

https://www.ecosystem.drgpcr.com/explore-individuals

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How Organizations can benefit from Dr. GPCR Ecosystem? 

https://www.ecosystem.drgpcr.com/explore-organizations

------------------------------------------- 

Become a #DrGPCR Ecosystem Member 

https://www.ecosystem.drgpcr.com/plans-pricing

-------------------------------------------  

Imagine a world in which the vast majority of us are healthy.  

The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.   

To build our #GPCR Ecosystem, we created various enabling outlets.  

- Individuals 

https://www.ecosystem.drgpcr.com/explore-individuals 

- Organizations 

https://www.ecosystem.drgpcr.com/explore-organizations

-------------------------------------------  

Are you a #GPCR professional?   

-   Subscribe to #DrGPCR monthly newsletter 

http://www.drgpcr.com/newsletter/ 

-   Listen and subscribe to #DrGPCR Podcasts  

http://www.drgpcr.com/podcast/ 

-   Listen and watch GPCR focused scientific talks at #VirtualCafe 

https://www.drgpcr.com/virtual-cafe/