Antibuddies (Antibuddies 204813)
Explorez tous les épisodes de Antibuddies
| Date | Titre | Durée | |
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| 23 Oct 2022 | Bep37 - You won't believe what your eosinophils are doing! | 00:47:57 | |
In this Buddisode, we sit down with Dr. Emilie Cosway from the Institute of Immunology and Immunotherapy at the University of Birmingham (UK) to discuss her recent paper about the mechanisms behind thymic regeneration. | |||
| 15 Nov 2022 | Bep38 - Yin and Yang of Tfh | 00:50:56 | |
In this Buddisode, we sit down with Dr. Simon Bélanger from the La Jolla Institute of Immunology (currently at Vir Biotechnology) to discuss his work on a transcription factor that can define early T follicular helper cell fate. | |||
| 02 Oct 2019 | Ep1 - The birth of Immunology | ||
In the first episode of the immunology 101 series, Autumn and Jatin talk about the pioneering scientists whose work gave birth to the field of immunology and medicine. Check out our memes on Facebook (@antibuddies) and Twitter (@antibuddies1). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Send us your queries/questions/suggestions at antibuddies1@gmail.com. Sources: 1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1200696/ 2. Kuby immunology (5th edition) | |||
| 02 Oct 2019 | Ep2 - Types of Immunity | ||
In the second episode, Autumn and Jatin talk about the various types of immunity. Check out our memes on Facebook (@antibuddies) and Twitter (@antibuddiesP). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Send us your queries/questions/suggestions at antibuddies1@gmail.com. Sources: 1. https://jnnp.bmj.com/content/71/1/62 2. https://www.nobelprize.org/prizes/uncategorized/nobel-prizes-and-the-immune-system 3. https://www.cdc.gov/vaccinesafety/concerns/autism.html | |||
| 18 Oct 2019 | Ep3 - Genesis of the immune system | ||
In the 3rd episode of our immunology 101 series, we talk about the birth of the immune system and faith of an immune cell after it has served its function. We also touch upon the role of stem cells and how differentiation works at the genetic and epigenetic level. Check out our memes on Facebook (@antibuddies) and Twitter (@antibuddiesP). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Send us your queries/questions/suggestions at antibuddies1@gmail.com. Sources: 1. Kuby Immunology 2. https://stemcells.nih.gov/info/2001report/chapter5.htm 3. https://www.nature.com/articles/pr2006122
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| 16 Nov 2019 | Ep4 - Cells of the immune system | ||
In the 4th episode of Immunology 101 series, Jatin tells a joke which is not even funny. We also talk about the cells of the immune system and what they do. Check out our memes on Facebook (@antibuddies) and Twitter (@antibuddiesP). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Send us your queries/questions/suggestions at antibuddies1@gmail.com. Sources:
1. Kuby Immunology | |||
| 08 Dec 2019 | Bep1 - Exosomes are cool | ||
In this buddisode, Dr. Winni Hui talks about her recently published work with exosomes secreted by salmonella infected macrophages. Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) You can read here paper here: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/29158431/ | |||
| 25 Feb 2020 | Bep2 - T cell responses against SARS Coronavirus | ||
In this buddisode, Tanu, a PhD student in virology, tells us about the SARS coronavirus that is related to the CoVID 19 currently in discussion worldwide. We then talk about an article looking at T cell responses to the SARS coronavirus. Nick, Jonathan, and Amari are undergrads joining this discussion. Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Check out our memes on Facebook (@antibuddies) and Twitter (@antibuddiesP). Send us your queries/questions/suggestions at antibuddies1@gmail.com. Source: | |||
| 30 Mar 2020 | Bep3 - Immunity against COVID19 / SARS CoV2 | ||
In this buddisode, Tanu and Jatin discuss about a SARS CoV2 patient case study who recovered from non-severe COVID19. Check out our memes on Facebook (@antibuddies) and Twitter (@antibuddiesP). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Send us your queries/questions/suggestions at antibuddies1@gmail.com. Source: | |||
| 07 Apr 2020 | Bep4 - Dieting improves T memory response | ||
In this buddisode, Antia and Jatin discuss about a recent study that shows improved secondary immune responses during dietary restriction. Also, Antia cannot pronounce glucocorticoids. Check out our memes on Facebook (@antibuddies) and Twitter (@antibuddiesP). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Send us your queries/questions/suggestions at antibuddies1@gmail.com. Source: | |||
| 17 Apr 2020 | Bep5 - B and T cells have different metabolic requirements | ||
In this buddisode, Antia and Jatin discuss about a recent study from 2016 that highlights the different metabolic requirements of T and B cells under homeostatic conditions. Also, Antia cannot pronounce the word "extrinsic". There is some background noise in the later half because someone had to cook food. Check out our memes on Facebook (@antibuddies) and Twitter (@antibuddiesP). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Send us your queries/questions/suggestions at antibuddies1@gmail.com. Source: | |||
| 24 Apr 2020 | Bep6 - The miracle drug for COVID19? | ||
In this buddisode, Tanu and Jatin discuss about the WHO mega trial, the breakthrough french study, and discuss some research articles investigating the efficacy of hydroxychloroquine and NHC.
Check out our memes on Facebook (@antibuddies) and Twitter (@antibuddiesP). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Send us your queries/questions/suggestions at antibuddies1@gmail.com.
Sources:
https://stm.sciencemag.org/node/213730.full
https://www.nature.com/articles/s41421-020-0156-0 | |||
| 07 May 2020 | Bep7 - Major love compatibility complex? | ||
In this buddisode, Tanu and Jatin discuss about HLA's association with body odor, mate selection, and procreation in humans.
Check out our memes on Facebook (@antibuddies) and Twitter (@antibuddiesP). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Send us your queries/questions/suggestions at antibuddies1@gmail.com.
Sources:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2519788/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1688704/
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| 30 May 2020 | Bep8 - Cancer nano-immunotherapy #1 | 00:56:30 | |
In this Buddisode, Antia and Jatin discuss about the recent developments in cancer nano medicine. Part 2 will be out soon. Check out our memes on Facebook (@antibuddies) and Twitter (@antibuddiesP). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Send us your queries/questions/suggestions at antibuddies1@gmail.com. Check out Public journal club here https://www.facebook.com/Publicjournalclub/ Sources: | |||
| 09 Jun 2020 | Bep9 - Cancer nano-immunotherapy #2 | 00:39:27 | |
In this Buddisode, Antia and Jatin continue to discuss about the recent developments in cancer nano medicine. Check out our memes on Facebook (@antibuddies) and Twitter (@antibuddiesP). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Send us your queries/questions/suggestions at antibuddies1@gmail.com. Sources: | |||
| 23 Jul 2020 | Bep10 - To IL2 or not to IL2 | 01:03:27 | |
In this Buddisode, Antia and Jatin discuss about the unique profiles of T cells that produce and/or respond to Interleukin 2. What determines whether a T cell will produce IL-2 or not? Find out in this episode. Check out our memes on Facebook (@antibuddies) and Twitter (@antibuddiesP). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our youtube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Sources: | |||
| 06 Aug 2020 | Monolog 1 - No mercy for cancer | 00:12:09 | |
In this monolog, Jatin briefly discusses the recent study from Lai et al. about FLT3L-secreting CAR T cells that successfully elicited a polyclonal immune response in Her2 and OVA co-expressing tumor models. Check out our memes on Facebook (@antibuddies) and Twitter (@antibuddiesP). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our Youtube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Sources: https://www.nature.com/articles/s41590-020-0676-7 (Original article) https://www.nature.com/articles/s41590-020-0740-3 (News and views) | |||
| 27 Aug 2020 | Monolog 2 - Don’t blame the butter for what the bread did | 00:09:25 | |
In this monolog, Tanu briefly discusses the recent study from Ang et al. about the effect of ketogenic diet on gut microbiota and Th17 cells. There are three diets discussed in the episode based on fat to carb ratio: the standard or baseline diet (35:50), high fat diet (75:10), and ketogenic diet (90:0). Check out our memes on Facebook (@antibuddies) and Twitter (@antibuddiesP). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our Youtube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com.
Source: https://www.sciencedirect.com/science/article/abs/pii/S0092867420304906 | |||
| 20 Sep 2020 | Bep11 - Colonic Tregs and Mom | 01:06:00 | |
In this buddisode, Eugenio, Jatin, and Natalie discuss about the a unique mode of non-genetic multigenerational inheritance in colonic Tregs. Check out our memes on Facebook (@antibuddies) and Twitter (@antibuddiesP). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com.
Source: https://www.sciencedirect.com/science/article/abs/pii/S0092867420304931 | |||
| 04 Oct 2020 | Bep12 - Anxie-T cells | 01:06:04 | |
In this buddisode, Eugenio, Jatin, and Natalie discuss about the a the role T cells in anxiety in murine models. Check out our memes on Facebook (@antibuddies) and Twitter (@antibuddiesP). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com.
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| 26 Oct 2020 | Bep13 - Viruses STING! | 00:53:04 | |
In this episode, Eugenio, Jatin, and Natalie discuss about the a the role of STING's Interferon-independent pathways in T cells and macrophages. Check out our memes on Facebook (@antibuddies) and Twitter (@antibuddiesP). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com.
Source: https://www.sciencedirect.com/science/article/abs/pii/S1074761320302648?via%3Dihub | |||
| 06 Nov 2020 | Monolog 3 - Why aren't we all autoimmune? | 00:06:18 | |
In this monolog, Jatin talks about some pioneering studies from the early 2000s that unraveled the mystery behind central tolerance. Check out our memes on Facebook (@antibuddies) and Twitter (@antibuddiesP). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our Youtube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. | |||
| 21 Nov 2020 | Bep14 - Why B cells need co-stimulation? | 00:52:24 | |
In this buddisode, Eugenio, Jatin, and Natalie discuss about the requirement of 2nd signal in B cells.
Check out our memes on Facebook (@antibuddies) and Twitter (@antibuddiesP). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw
Send us your queries/questions/suggestions at antibuddies1@gmail.com. Article of discussion: https://www.nature.com/articles/s41590-020-0765-7 | |||
| 08 Dec 2020 | Bep15 - Mitochondria is the powerhouse of TILs. | 00:56:38 | |
In this buddisode, we sit down with Dr. Yi-ru Yu, a post doctoral researcher at the department of oncology (University of Lausanne, Switzerland) to talk about his recent article studying mitochondrial dynamics in the exhaustion of tumor infiltrating lymphocytes (TILs). Check out our memes on Facebook (@antibuddies) and Twitter (@antibuddiesP). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw
Send us your queries/questions/suggestions at antibuddies1@gmail.com. Article of discussion: Disturbed mitochondrial dynamics in CD8 + TILs reinforce T cell exhaustion | Nature Immunology | |||
| 17 Jan 2021 | Ep5 - Gene Rearrangement in B cells [Part 1] | 00:55:15 | |
In the 5th episode of Immunology 101 series, Eugenio, Jatin, Natalie, and Samriti talk about the how such an enormous antibody diversity is generated in B cells with limited antibody-coding genes. Jatin also tries to tell a joke which is not funny. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our bimonthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Sources:
1. Kuby Immunology 2. Fun fact sources: | |||
| 24 Jan 2021 | Bep16 - Decoy exosomes for defense | 00:57:04 | |
In this buddisode, we sit down with Dr. Ken Cadwell from New York University to talk about his recent article about decoy exosomes secreted by epithelial cells to defend against bacterial toxins. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Article of discussion: Decoy exosomes provide protection against bacterial toxins | Nature | |||
| 15 Feb 2021 | Bep17 - IgM: the key to early neoantigen recognition | 01:04:33 | |
In this buddisode, Eugenio, Natalie, and Jatin sit down with Dr. Claudia Jakubzick from Dartmouth University. They discus Claudia's 2018 publication that elucidated the role of natural IgM in the recognition of neoantigens in absence of PAMPs. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Article of discussion: Immune Surveillance by Natural IgM Is Required for Early Neoantigen Recognition and Initiation of Adaptive Immunity (nih.gov) | |||
| 23 Feb 2021 | Monolog 4 - lnc between RNA and CSR. | 00:20:15 | |
In this monolog, Natalie talks about how long non-coding RNAs alter chromosomal conformation to affect class switching in B cells. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Article of discussion: Noncoding RNA transcription alters chromosomal topology to promote isotype-specific class switch recombination | Science Immunology (sciencemag.org) | |||
| 01 Mar 2021 | Bep18 - Extrafollicular T cells in SLE | 01:20:57 | |
In this Buddisode, Eugenio, Natalie, and Jatin sit down with Dr. Deepak Rao from Harvard Medical School and discuss about his lab's 2019 publication about peripheral helper T cells that could potentially be providing help to B cells outside the follicles. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Article of discussion: PD-1hiCXCR5– T peripheral helper cells promote B cell responses in lupus via MAF and IL-21 (nih.gov) | |||
| 14 Mar 2021 | Bep19 - A new spin to T cell flavors | 00:54:20 | |
In this Buddisode, Eugenio, Natalie, and Jatin sit down with Dr. Evgeny Kiner from Immunai and discuss about his earlier publication about a continuum of T helper phenotypes seen in vivo. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Article of discussion: Gut CD4 + T cell phenotypes are a continuum molded by microbes, not by T H archetypes | Nature Immunology
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| 28 Mar 2021 | Ep6 - Gene Rearrangement in B cells [Part 2] | 00:46:22 | |
In the 6th episode of Immunology 101 series, Jatin and Natalie talk about the mechanism of VDJ recombination, its epigenetic aspect, and the steps that follow a successful heavy chain rearrangement. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Join us on our bimonthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Sources:
1. Kuby Immunology 2. Most α/β T Cell Receptor Diversity Is Due to Terminal Deoxynucleotidyl Transferase (nih.gov) | |||
| 12 Apr 2021 | Ep7 - Gene Rearrangement in T cells | 00:24:21 | |
In the 7th episode of Immunology 101 series, Dara, Eugenio, Jatin, and Natalie talk about the discovery of the T cell receptors, the mechanism of VDJ recombination in T cells, and comparison of VDJ recombination in T and B cells. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Join us on our bimonthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Sources:
1. Kuby Immunology | |||
| 28 Apr 2021 | Bep20 - Germinal centers in severe COVID19 patients | 01:00:31 | |
In this Buddisode, Eugenio, Dara, and Jatin sit down with Dr. Shiv Pillai from Harvard medical school to discuss about his lab's recent publication about the state of germinal centers in severe COVID19 Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Article of discussion: The loss of Bcl-6 expressing T follicular helper cells and the absence of germinal centers in COVID-19 (nih.gov)
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| 11 May 2021 | Bep21 - Neuroinvasive SARS CoV2 | 01:17:10 | |
In this Buddisode, Eugenio, Tanu, and Jatin sit down with Dr. Eric Song from Yale School of Medicine to discuss his recent publication that associates neuroinvasive properties with SARS CoV2. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Article of discussion: Neuroinvasion of SARS-CoV-2 in human and mouse brain | Journal of Experimental Medicine | Rockefeller University Press (rupress.org)
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| 07 Jun 2021 | Ep8 - T cell development #1 | 00:33:23 | |
In the 8th episode of Immunology 101 series, Dara, Jatin, and Natalie talk about the steps in the development of T cells and how self love is important, to an extent. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Join us on our bimonthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Sources:
1. Kuby Immunology | |||
| 29 Jun 2021 | Ep9 - T cell development #2 | 00:34:14 | |
In the 9th episode of Immunology 101 series, Dara, Jatin, and Natalie continue talking about T cell development with some details on the molecular level. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Join us on our bimonthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Sources:
1. Kuby Immunology | |||
| 05 Jul 2021 | Bep22 - Your immune cells determine how fast you age | 01:01:49 | |
In this Buddisode, Eugenio, Natalie, and Jatin sit down with Drs. Rafael Flores and Matthew Yousefzadeh to discuss their recent research that aims to dissect the role of the immune system in systemic aging. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Article of discussion: An aged immune system drives senescence and ageing of solid organs | Nature
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| 18 Jul 2021 | Monolog 5 - Endogenous retroviruses in skin immunity | 00:12:46 | |
In this monolog, Tanu talks about the effect of diet, microbiota, and the endogenous retroviral elements in skin inflammation. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Article of discussion: https://www.sciencedirect.com/science/article/abs/pii/S0092867421006504 | |||
| 25 Jul 2021 | Bep23 - B cells in the Brain | 01:03:08 | |
In this Buddisode, Eugenio, Natalie, and Jatin sit down with Dr. Wei-le Wang who is a posdoc in the lab of Dr. Marco Colonna lab at Washington University, St. Louis. The discussion entails Wei-le's recent publication that finds a unique niche around the CNS where new immune cells are formed. | |||
| 01 Aug 2021 | Bep24 - Type I vs Type II interferons in autoimmunity | 00:48:01 | |
In this Buddisode, Dara & Jatin sit down with Adam Fike from Ziaur Rahman's lab at Penn State University. The discussion entails their 2020 publication that teased apart the contribution of Type I and Type II interferons in TLR7-mediated systemic autoimmunity. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Article of discussion: Type II but Not Type I IFN Signaling Is Indispensable for TLR7-Promoted Development of Autoreactive B Cells and Systemic Autoimmunity | The Journal of Immunology (jimmunol.org)
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| 15 Aug 2021 | Ep10 - B cell development in the bone marrow | 00:35:04 | |
In the 10th episode of Immunology 101 series, Dara, Jatin, and Natalie talk about B cell development in the bone marrow, some key transcription factors involved in the process, and the hardy fractions. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Join us on our bimonthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Sources: 1. Kuby Immunology | |||
| 30 Aug 2021 | Bep25 - Microbe-specific thymocyte development | 00:52:32 | |
In this Buddisode, Dara, Eugenio, Natalie, & Jatin sit down with Daniel from Gretchen Diehl's lab at Memorial Sloan Kettering Cancer Center, NY. The discussion entails their 2021 paper about the development of bacteria-specific T cells in the thymus of young mice and all the implications surrounding this discovery. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Article of discussion: Thymic development of gut-microbiota-specific T cells | Nature
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| 14 Sep 2021 | Bep26 - Phase separation in Immune Signaling #1 | 00:47:37 | |
In this Buddisode, Eugenio, Natalie, & Jatin sit down with Xiaolei Su, Qian Xiao, and Ceara McAtee from Yale cancer center at Yale university to discuss their latest review article published in Nature Immunology Reviews in July of 2021. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Article of discussion: Phase separation in immune signalling | Nature Reviews Immunology
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| 21 Sep 2021 | Bep27 - Phase separation in Immune Signaling #2 | 00:35:26 | |
In the 2nd part of the phase separation series, Eugenio, Natalie, & Jatin sit down with Xiaolei Su, Qian Xiao, and Ceara McAtee continue their discussion. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Article of discussion: Phase separation in immune signalling | Nature Reviews Immunology
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| 26 Sep 2021 | Bep28 - Origin of Eukaryotes and the TCA cycle #1 | 00:47:33 | |
In the 1st part of the Origin of Eukaryotes series, Dara and Jatin sit down with Dr. Dylan G Ryan from University of Cambridge (formerly at Trinity College Dublin) to discuss his 2020 perspective article about the role of TCA cycle in Eukaryogenesis. | |||
| 02 Oct 2021 | Bep29 - Origin of Eukaryotes and the TCA cycle #2 | 00:31:27 | |
In the 2nd part of the Origin of Eukaryotes series, Dara and Jatin sit down with Dr. Dylan G Ryan from University of Cambridge (formerly at Trinity College Dublin) to discuss his 2020 perspective article about the role of TCA cycle in Eukaryogenesis. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Article of discussion: TCA cycle signalling and the evolution of eukaryotes (nih.gov)
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| 19 Oct 2021 | Ep11 - B cell development in the spleen | 00:30:01 | |
Immunology 101 | |||
| 26 Oct 2021 | Monolog 6 - TIM3 and Breast cancer | 00:15:22 | |
In this breast cancer awareness month special monolog, Tanu talks about the challenges faced for breast cancer research and finding an effective treatment that works for everyone. | |||
| 10 Nov 2021 | Ep12 - Innate immunity and TLR signaling | 00:36:44 | |
In the 12th episode of Immunology 101 series, Natalie and Jatin shift gears to talk about Innate immunity with a focus on TLR signaling. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Join us on our bimonthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Sources: Kuby Immunology | |||
| 24 Nov 2021 | Ep13 - Innate immunity and other PRRs | 00:34:18 | |
In the 13th episode of Immunology 101 series, Natalie and Jatin continue talking about PRR signaling. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Join us on our bimonthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Sources: Kuby Immunology | |||
| 05 Jan 2022 | Monolog 7 - Cancer is an immune disease | 00:14:21 | |
In this monolog, Natalie explains how cancer is a disease of the immune system. | |||
| 17 Jan 2022 | Bep30 - Finding the right clone | 00:59:01 | |
We sit down with Dr. Yosuke Kumamoto from Rutgers new jersey medical school to discuss the role of a specific subset of DCs that retain lymphocytes in the SLOs to scan the repertoire post-immunization. | |||
| 29 Jan 2022 | Monolog 8 - Neuroimmune interactions | 00:09:38 | |
In this monolog, Vijay highlights some of the interactions between the neurons and the immune cells that show an intricately woven neuroimmune network. | |||
| 08 Feb 2022 | Monolog 9 - Why do we lose smell after COVID19? | 00:08:07 | |
In this monolog, Tanu breaks down a recent study that elucidates the mechanism behind the loss of sense of smell in COVID19 patients. | |||
| 18 Feb 2022 | Bep31 - 6 shades of NF-kB #1 | 00:49:54 | |
We sit down with Dr. Adewunmi Adelaja (M.D., Ph.D.) from the University of California Los Angeles to discuss NFkB signaling and how signals to different stimuli are relayed inside macrophages. | |||
| 27 Feb 2022 | Bep32 - 6 shades of NF-kB #2 | 00:52:19 | |
We continue our discussion with Dr. Adewunmi Adelaja (M.D., Ph.D.), from the University of California Los Angeles, about NFkB signaling and how signals to different stimuli are relayed inside macrophages. | |||
| 21 Mar 2022 | Bep33 - Transgenerational trained immunity | 00:52:32 | |
Eugenio and Jatin sit down with Dr. Jorge-Dominguez Andres (Ph.D.) from Radboud University to discuss trained immunity and its transgenerational inheritance in mice. | |||
| 31 Mar 2022 | Ep14 - Innate Immune Cells | 00:28:15 | |
In the 14th episode of Immunology 101 series, Natalie and Jatin talk about the cellular facet of the innate immune system. | |||
| 21 Apr 2022 | Ep15 - Regulation of Innate Immunity | 00:33:09 | |
Natalie and Jatin talk about positive and negative regulation in immune response, how the cells of the innate immunity interact with the adaptive, and the ubiquity of the immune system across phyla. | |||
| 21 Jun 2022 | Bep34 - A tale of labor, pre-term birth, and IL-22 | 01:15:17 | |
We sit down with Dr. Nardhy Gomez-Lopez from the Department of Obstetrics and Gynecology at Wayne State University to discuss her recent paper about the role of IL-22 in pregnancy and pre-term births. | |||
| 09 Aug 2022 | Ep16 - Pathways of the Complement System | 00:30:43 | |
In the 16th episode of Immunology 101 series, Natalie and Jatin talk about an undergrad's worst nightmare 2 months into the immunology course - The complement system. | |||
| 07 Sep 2022 | Bep35 - Aging affects Central Tolerance | 01:02:44 | |
We sit down with Dr. Jessica Lancaster from the Department of Immunology, Mayo clinic to discuss her recent paper about the effect of Aging on Central Tolerance and Treg induction. | |||
| 29 Sep 2022 | Bep36 - IL17A and ICI-induced autoimmune thyroiditis | 00:43:32 | |
In this buddisode, we sit down with Dr. Melissa Lechner from the Division of Endocrinology, Diabetes, and Metabolism at the UCLA David Geffen School of Medicine to discuss her recent paper about the mechanisms behind immune checkpoint inhibitor-induced autoimmune thyroiditis. | |||
| 25 Jun 2023 | Ep22 - B cells in the germinal center | 00:29:03 | |
In the 22nd episode of our Immunology 101 series, Ash, Koshika, and Jatin talk about the events of the germinal centers. | |||
| 15 Jul 2023 | Ep23 - Somatic hypermutation and Class switching | 00:22:42 | |
In the 23rd episode of our Immunology 101 series, Ash, Koshika, and Jatin discuss the events taking place inside the germinal center - class switching and somatic hypermutation. | |||
| 13 Aug 2023 | Ep24 - Antibody effector functions | 00:22:18 | |
In the 24th episode of our Immunology 101 series, Ash and Jatin discuss the various effector functions of Antibodies | |||
| 10 Sep 2023 | Ep25 - Fc receptors & Antibody isotypes | 00:32:42 | |
In the 25th episode of our Immunology 101 series, Koshika and Jatin discuss Fc receptors and Antibody isotypes and relate them to specific effector functions. | |||
| 21 Oct 2023 | Ep26 - Cytotoxic T cells | 00:30:26 | |
In the 26th episode of our Immunology 101 series, Ash and Jatin shift gears from humoral immunity to cellular immunity and discuss cytotoxic T cell activation. | |||
| 12 Nov 2023 | Ep27 - The kiss of death | 00:28:12 | |
In the 27th episode of our Immunology 101 series, Ash and Jatin talk about how cytotoxic T cells deliver the kiss of death to their targets. | |||
| 23 Dec 2023 | Ep28 - The Natural killers | 00:36:09 | |
In the 28th episode of our Immunology 101 series, Ash and Jatin talk continue discussion on cytotoxic T cells and transition into their functional cousins - the natural killer cells. | |||
| 16 Jan 2024 | Monolog 12 - Gut is the multiverse of neuroimmune activities | 00:09:35 | |
In this monolog, Vijay talks about a 2016 article from Rockefeller University about the complex crosstalk in the gut between the neurons and macrophages. | |||
| 21 Jan 2024 | Monolog 13 - Sleep tight, don't let the cytokine storm bite | 00:12:42 | |
In this monolog, Casey talks about a 2023 article from the National Institute of Biological Sciences (Beijun, China) about the role of cytokines and immune cells in sleep deprivation-induced mortality.
Source: Prolonged sleep deprivation induces a cytokine-storm-like syndrome in mammals - PubMed (nih.gov) | |||
| 30 Jan 2024 | Monolog 14 - Sterile inflammation | 00:11:10 | |
In this monologue, Akshat talks about sterile inflammation, or leucocyte activation in the absence of inflammatory responses. These carefully regulated "internal affairs" of the immune system can be pathological or protective. | |||
| 04 Feb 2024 | Ep29 - Barrier immunity & the gut | 00:21:46 | |
In the 29th episode of our Immunology 101 series, Ash and Tanu start the new year 2024 with a discussion on Barrier Immunity with a focus on the gut. | |||
| 07 Mar 2024 | Monolog 15 - The Liver is Bile-lingual | 00:16:12 | |
In this Monolog, Akshat discusses how the liver "speaks" both immunity and metabolism via bile to control hepatic tumors. Liver X Receptors also make an appearance. | |||
| 29 Jul 2024 | Monolog 17 - CAR-T and TCR-T Cells Face Off! | 00:15:28 | |
In this episode, Akshat outlines the salient features of CAR or TCR-engineered T cells, and deigns to ponder: is one modality just objectively better than the other? | |||
| 27 Aug 2024 | Monolog 18 - Interleakin' | 00:12:45 | |
In this monolog, Akshat ponders about the spatiotemporal underpinnings of cytokine concentrations in tissue niches...and how it all appears to function like a gossip network.
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| 23 Sep 2024 | Monolog 19 - Term vs Pre-term immune development | 00:11:33 | |
In this monolog, Vijay discusses the difference in immune system development in term and pre-term babies.
Sources: https://pubmed.ncbi.nlm.nih.gov/30142345/ | |||
| 07 Oct 2024 | Monolog 20 - The Fountain of IL-11 Youth | 00:10:51 | |
In this monolog, Casey discusses a 2024 article about the increase in health and lifespan in mammals after IL-11 inhibition. | |||
| 27 Dec 2022 | Monolog 10 - Evolution of Immunity | 00:12:20 | |
In this monolog, Natalie talks about the evolutionary history of the immune system. | |||
| 05 Feb 2023 | Ep17 - T cell activation | 00:40:11 | |
In the 17th episode of Immunology 101 series, Natalie and Jatin talk about the T cell activation process and make some very lame jokes. | |||
| 15 Mar 2023 | Bep39 - How SARS CoV2 aces cytotoxic T cells | 01:13:46 | |
In this Buddisode, we sit down with Drs. Cosima T Baldari & Rino Rappuoli to discuss their work on a unique immune evasion strategy deployed by SARS CoV2 to paralyze cytotoxic T cells. | |||
| 26 Mar 2023 | Ep18 - T helper classification and polarization | 00:31:06 | |
In the 18th episode of Immunology 101 series, Ash, Koshika, and Jatin talk about classification of T helper cells and their functions. | |||
| 02 Apr 2023 | Ep19 - Memory T cells | 00:28:09 | |
In the 19th episode of the Immunology 101 series, Ash, Koshika, and Jatin talk continue their conversation about T cell subsets with a focus on memory T cells. | |||
| 23 Apr 2023 | Ep20 - B cells are mean | 00:26:00 | |
In the 20th episode of Immunology 101 series, Ash, Koshika, and Jatin shift gears to talk about B cell activation and draw parallels with T cell activation process. | |||
| 05 May 2023 | Monolog 11 - Neuro-Pancreas Chat | 00:11:59 | |
In this monolog, Vijay talks about a recent article describing the communication between the vagus nerve and the pancreas. | |||
| 15 May 2023 | Bep40 - Non-canonical T cell activation in TDLNs | 01:11:43 | |
In this Buddisode, we sit down with Dr. Nataliya Prokhnevska to discuss her work on the fate and role of non-cytotoxic CD8+ T cells found in the tumor-draining lymph nodes of cancer patients.
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| 04 Jun 2023 | Ep21 - Fate of a B cell | 00:40:13 | |
In the 21st episode of our Immunology 101 series, Ash and Jatin talk about the fate of the B cell after it encounters the antigen and how it travels through the various compartments of a secondary lymphoid organ. | |||