The Rounds Table (Dr. John Fralick and Dr. Michael Fralick)

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Welcome back Rounds Table Listeners!

In this throwback episode, Drs. Mike and John Fralick discuss two papers exploring  early metformin in Gestational Diabetes and tirzepatide versus short-acting insulin when added to basal insulin regimens in patients with Type II Diabetes. 

1. Early Metformin in Gestational Diabetes: A Randomized Clinical Trial (0:00 – 9:28).
2. Tirzepatide vs Insulin Lispro Added to Basal Insulin in Type 2 Diabetes: The SURPASS-6 Randomized Clinical Trial (9:28 – 19:00).

And for the Good Stuff:

• N.B. woman meets her Mississippi bone marrow donor a decade after donation (19:00 – 19:45).
• The Intern at Work Podcast (19:45 – 21:10).

Questions? Comments? Feedback? We’d love to hear from you! @roundstable

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Welcome back Rounds Table Listeners!

We are back today with our Classic Rapid Fire Podcast!

This week, Dr. Mike Fralick and special guest, Dr. Laiya Carayannopoulos from the Intern at Work Podcast, discuss two recent papers exploring the role tenecteplase between 4.5 and 24 hours in ischemic stroke and comparing fidaxomicin with vancomycin in treating C. difficile when patients are receiving concurrent antibiotics. Two papers, here we go!

1. Tenecteplase for Stroke at 4.5 to 24 Hours with Perfusion-Imaging Selection (0:00 – 15:20).
2. Comparing Fidaxomicin with Oral Vancomycin for the Treatment of C. difficile Infection in Hospitalized Patients Receiving Concomitant Antibiotics for Concurrent Infections (15:20 – 28:58).

Questions? Comments? Feedback? We’d love to hear from you! @roundstable

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Welcome back Rounds Table Listeners!

We are back today with our Classic Rapid Fire Podcast!

This week, Drs. Mike Fralick and Emily Hughes discuss two recent papers exploring the role of beta blockers after myocardial infarction when there is preserved ejection fraction and the utility of Paxlovid in vaccinated versus unvaccinated adult outpatients with symptomatic COVID-19. Two papers, here we go!

1. Nirmatrelvir for Vaccinated or Unvaccinated Adult Outpatients with COVID-19 (0:00 – 14:02).
2.  Beta-Blockers after Myocardial Infarction and Preserved Ejection Fraction (14:02 – 27:24).

And for the Good Stuff:

•  A 65-Year-Old Woman with an Incorrect Operation on the Left Hand (27:24 – 31:04).
• Bradycardia associated with remdesivir therapy for COVID-19 in a 59-year-old man

Questions? Comments? Feedback? We’d love to hear from you! @roundstable

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Welcome back Rounds Table Listeners!

In this throwback episode, Drs. John and Mike Fralick discuss two papers – one, exploring IVIG in the treatment of dermatomyositis, and the second investigating the effect of tranexamic acid in patients with acute gastrointestinal bleeding.

1. Trial of Intravenous Immune Globulin in Dermatomyositis (0:00 – 8:38).
2. Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international, randomised, double-blind, placebo-controlled trial (8:38 – 18:04).

And for the Good Stuff:

• Alberta using humour to attract workers (18:04 – 18:50).
• CBME in Residency Education (18:50 – 21:02).

Questions? Comments? Feedback? We’d love to hear from you! @roundstable

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Welcome back Rounds Table Listeners!

We are back today with our Classic Rapid Fire Podcast!

This week, Drs. Mike and John Fralick discuss two recent papers exploring the role of ticagrelor with aspirin versus ticagrelor alone after percutaneous coronary intervention in acute MI and the efficacy of empagliflozin after acute MI. Two papers, here we go!

1. Ticagrelor alone versus ticagrelor plus aspirin from month 1 to month 12 after percutaneous coronary intervention in patients with acute coronary syndromes (ULTIMATE-DAPT) (0:00 – 9:22).
2.  Empagliflozin after Acute Myocardial Infarction (9:22 – 16:00).

And for the Good Stuff:

• Impact of presentation at conference with timed release of academic publication (16:00 – 17:32).
• Top spot in the PWHL and attendance record at stake in latest Montreal-Toronto showdown (17:32 – 19:59).

Questions? Comments? Feedback? We’d love to hear from you! @roundstable

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Welcome back Rounds Table Listeners!

In this throwback episode, Drs. Mike Fralick and Justin Boyle discuss two papers exploring intravenous iron infusions in heart failure with iron deficiency and in reducing blood transfusion requirements in patients with hip fracture. Check it out below!

1. Ferric Carboxymaltose in Heart Failure with Iron Deficiency (0:00 – 8:12).
2. Ferric derisomaltose and tranexamic acid, combined or alone, for reducing blood transfusion in patients with hip fracture (the HiFIT trial) (8:12 – 19:00).

And for the Good Stuff:

• Pop Culture Nostalgia (19:00 – 19:33).
• Thrombo Trial Files (19:33 – 20:48).

Questions? Comments? Feedback? We’d love to hear from you! @roundstable

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Welcome back Rounds Table Listeners!

We are back today with a solo episode with Dr. John Fralick!

This week, he will discuss a paper exploring a modification of the Valsalva manoeuvre for the treatment of supraventricular tachycardias. Here we go!

1. Postural modification to the standard Valsalva manoeuvre for emergency treatment of supraventricular tachycardias (REVERT) (0:00 – 7:00).

And for the Good Stuff:

•  Live Transcribe (7:00 – 8:16).

Questions? Comments? Feedback? We’d love to hear from you! @roundstable

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Welcome back Rounds Table Listeners!

We are back today with a solo episode with Dr. Mike Fralick!

This week, he will discuss a recent paper exploring the efficacy of tirzepatide in treating obstructive sleep apnea and obesity. Here we go!

1. Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity

Check out the New Motto!

Questions? Comments? Feedback? We’d love to hear from you! @roundstable

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Welcome back Rounds Table Listeners!

In this throwback episode, Drs. Mike and John Fralick discuss the use of semaglutide in patients with obesity without diabetes and changes in renal function after starting dapagliflozin in patients with heart failure. Check it out below!

1. Decline in Estimated Glomerular Filtration Rate After Dapagliflozin in Heart Failure With Mildly Reduced or Preserved Ejection Fraction: A Prespecified Secondary Analysis of the DELIVER Randomized Clinical Trial (0:00 – 09:40).
2. Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes (09:40 – 19:24).

And for the Good Stuff:

• How Ozempic and Weight Loss Drugs Are Reshaping Denmark’s Economy (19:24 – 19:58).
• How a Canadian scientist and a venomous lizard helped pave the way for Ozempic (19:58 – 23:36).

Questions? Comments? Feedback? We’d love to hear from you! @roundstable

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Welcome back Rounds Table Listeners!

In this throwback episode, Drs. John Fralick and Justin Boyle discuss early versus late anticoagulation after stroke with atrial fibrillation and dual antiplatelet therapy versus alteplase in minor ischemic stroke.

1. Early versus Later Anticoagulation for Stroke with Atrial Fibrillation (0:00 – 8:48).
2. Dual Antiplatelet Therapy vs Alteplase for PatientsWith Minor Nondisabling Acute Ischemic Stroke: The ARAMIS Randomized Clinical Trial (8:48 – 16:20).

And for the Good Stuff:

• Taylor Swift makes history with more No. 1 albums than any female artist (16:20 – 17:03).
• ‘I finally did it’: Ottawa’s Michael Woods wins 9th stage of Tour de France (17:03 – 18:00).

Questions? Comments? Feedback? We’d love to hear from you! @roundstable

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Welcome back Rounds Table Listeners!

We are back today with our Classic Rapid Fire Podcast!

This week, Drs. John Fralick and Justin Boyle discuss two recent papers exploring the role of semaglutide in CKD in patients with Type II Diabetes and the utility of tirzepatide in metabolic dysfunction-associated steatohepatitis with liver fibrosis. Two papers, here we go!

1. Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes (0:00 – 09:32).
2. Tirzepatide for Metabolic Dysfunction-Associated Steatohepatitis with Liver Fibrosis (09:32 – 17:06).

And for the Good Stuff:

• Congratulations to everyone starting/progressing through residency/finishing their training! (17:06 – 17:43).
• Calgary officials aiming for 'low end' of repair timeline after pipes arrive from San Diego (17:43 – 19:06).

Questions? Comments? Feedback? We’d love to hear from you! @roundstable

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Welcome back Rounds Table Listeners!

We are back today with our Classic Rapid Fire Podcast!

This week, Drs. Mike and John Fralick discuss two recent papers exploring the role of acupressure in pain management for knee osteroarthritis and the utility of AI-enabled electrocardiography. Two papers, here we go!

1. Self-Administered Acupressure for Probable Knee Osteoarthritis in Middle-Aged and Older Adults (0:00 – 09:02).
2. AI-enabled electrocardiography alert intervention and all-cause mortality: a pragmatic randomized clinical trial (09:02 – 23:16).

And for the Good Stuff:

• 100-year-old veteran parachutes out of a plane, raising over $100K for SickKids hospital (23:16 – 23:50).
• One-Pagers for the Wards (23:50 – 25:15).

Questions? Comments? Feedback? We’d love to hear from you! @roundstable

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Welcome back Rounds Table Listeners!

We are back this week with a special podcast episode! Dr. Mike Fralick sits down with Dr. Dirk von Lewinski, an Interventional Cardiologist, Intensivist, and Scientist from the Medical University of Graz, to chat about his practicing changing trial!

Questions? Comments? Feedback? We’d love to hear from you! @roundstable

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Welcome to Medicine Pods! Your one stop shop for everything internal medicine, prn. Find us at www.medicinepods.com to find everything from The Intern at Work, The Rounds Table, Everything You Need To Know and Trial Files all in one place.

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Welcome back Rounds Table Listeners!

We are back today with our Classic Rapid Fire Podcast!

This week, Dr. Mike Fralick and special guest, Dr. Laiya Carayannopoulos from the Intern at Work Podcast and our new Medicine Pods collaboration, discuss two recent papers exploring the novel management of two rare diseases - ATTR Amyloidosis and Hereditary Angioedema. Two papers, here we go!

1. Patisiran Treatment in Patients with Transthyretin Cardiac Amyloidosis (0:00 – 14:15).
2. Efficacy and Safety of Donidalorsen for Hereditary Angioedema (14:15 – 25:14).

And for the Good Stuff:

• Medicine Pods! (25:14 – 26:23).

Questions? Comments? Feedback? We’d love to hear from you! @roundstable

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Welcome to a special series Medicine Pods has created in collaboration with the Canadian Society of Internal Medicine (CSIM)!

In the lead up to the CSIM Conference, we will be discussing the runners up for the ever popular 'Top Papers' session. This year's session will be chaired by Dr. Raj Hanmiah, who has kindly joined us as a special guest for this series. If you want to find out which papers made the final cut, make sure to join us at the 'Top Papers' session on October 17th, where we will be there recording live! 

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome to Part 2 of a special series Medicine Pods has created in collaboration with the Canadian Society of Internal Medicine (CSIM)!

In the lead up to the CSIM Conference, we will be discussing the runners up for the ever popular 'Top Papers' session. This year's session will be chaired by Dr. Raj Hanmiah, who has kindly joined us as a special guest for this series. If you want to find out which papers made the final cut, make sure to join us at the 'Top Papers' session on October 17th, where we will be recording live! 

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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There are everyday practices we can stop or reduce that don’t add value to patient care and harm the environment.

In this special CSIM episode, host Dr. Zahra Merali sits down with guests Dr. Mathilde Gaudreau @MathildeGSimard (General Internist, University of Ottawa), Dr. Nabha Shetty (General Internist, Dalhousie University) and Dr. Valeria Stoynova (General Internist, Island Health/UBC Island Medical Program) to discuss 4 of the Choosing Wisely Canada’s climate-conscious recommendations (https://choosingwiselycanada.org/climate/).  They were integral in creating these recommendations, and have a wealth of practical tips about how we can implement them into our own practice! 

Infographic by Julia Simone (medical student). 

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome to Part 3 of a special series Medicine Pods has created in collaboration with the Canadian Society of Internal Medicine (CSIM)!

In the lead up to the CSIM Conference, we will be discussing the runners up for the ever popular 'Top Papers' session. This year's session will be chaired by Dr. Raj Hanmiah, who has kindly joined us as a special guest for this series. If you want to find out which papers made the final cut, make sure to join us at the 'Top Papers' session on October 17th, where we will be recording live! 

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Up to 30% of all healthcare offers no clinical value to patients. Reducing this care has the co-benefit of decreasing healthcare's carbon footprint.

In this special CSIM episode, host Dr. Zahra Merali sits down with guests Dr. Billy Silverstein @WKSilverstein (General Internist, University of Toronto) and Dr. Owen Luv @OwenLuo5 (Internal Medicine Resident, McGill University) to discuss 4 of the Choosing Wisely Canada’s climate-conscious recommendations (https://choosingwiselycanada.org/climate/).  They were integral in creating these recommendations, and have a wealth of practical tips about how we can implement them into our own practice! 

Infographic by Julia Simone (medical student). 

If you have not heard Part 1 - make sure to go back and listen to other Canada-wide experts in this area.

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Take a listen to our live recording of The Canadian Conference of Internal Medicine Top papers of the year 2024 session!
 
We talk about recent studies involving alzheimer's dementia, community acquired pneumonia, atrial fibrillation, MASLD and long covid.

Host: Dr. Zahra Merali, Expert: Dr. Rajender Hanmiah.

Check out www.medicinepods.com for a live video recording. You can also see a link to each paper there. 

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners!

We are back today with a special Rapid Fire Podcast!

This week, Drs. Mike Fralick and Justin Boyle discuss top papers from the 2024 European of Society of Cardiology Congress. Here we go!

1. Edoxaban Antithrombotic Therapy for Atrial Fibrillation and Stable Coronary Artery Disease (0:00 – 9:25).
2. Beta-Blocker Interruption or Continuation after Myocardial Infarction (9:25 – 13:52).
3. Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction (13:52 – 21:20).
4. Continuation vs. Discontinuation of Renin-Angiotensin System Inhibitors Before Major Non-Cardiac Surgery (21:20 – 28:51).

Of note, for prescribers in Ontario, there is now a limited use code for finerenone for patients that have both T2DM and CKD. 

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners!

We are back today with our Classic Rapid Fire Podcast!

This week, Drs. Mike Fralick and Justin Boyle discuss two recent papers exploring the effect of sitting time reduction on blood pressure and the discontinuation of RAAS inhibition perioperatively. Two papers, here we go!

1. Sitting Time Reduction and Blood Pressure in Older Adults (0:00 – 11:35).
2. Discontinuation versus continuation of renin-angiotensin system inhibition before non-cardiac surgery: the SPACE trial (11:35 – 21:32).

And for the Good Stuff:

• Summer McIntosh becomes 1st Canadian to win 3 gold medals at a single Olympic Games (21:32 – 22:37).
• One-Pagers for the Wards by Dr. Mike Fralick! (22:37 – 24:13)

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners!

We are back today with our Classic Rapid Fire Podcast!

This week, Drs. Mike and John Fralick discuss two recent papers - the Balance Trial and the role of inhaled amikacin in preventing VAP. Two papers, here we go!

1. Inhaled Amikacin to Prevent Ventilator-Associated Pneumonia (0:00 – 8:24).
2. Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections (the Balance Trial) (8:24 – 17:24).

And for the Good Stuff:

• The Tragically Hip: No Dress Rehearsal (17:24 – 18:30).
• www.powercalc.ca (18:30 – 20:06)

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners!

We are back today with our Classic Rapid Fire Podcast!

This week, Drs. Justin Boyle and Emily Hughes discuss two recent papers - the effect of dietary sodium on blood pressure and the role of decolonization in nursing homes to prevent infection. Two papers, here we go!

1. Effect of Dietary Sodium on Blood Pressure (0:00 – 10:05).
2. Decolonization in Nursing Homes to Prevent Infection and Hospitalization (10:05 – 20:45).

And for the Good Stuff:

• What Do Trainees Want? The Rise of House Staff Unions (20:45 – 22:48).
• Initiation of opioid agonist therapy after hospital visits for opioid poisonings in Ontario (22:48 – 24:39)

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners!

We are back this week with a special podcast episode! Dr. Mike Fralick sits down with Dr. Kevin Venus, a General Internist at Toronto Western Hospital, to chat about perioperative medicine!

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Happy Holidays Rounds Table Listeners! For our penultimate episode of 2024, we are back with a special treat! This week, Drs. Mike and John Fralick chat about the top five RCTs published over the past year:

1. Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction (0:00 – 3:40).
2. Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity (3:40 – 9:00).
3. Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes (9:00 – 13:55).
4. Tirzepatide for Metabolic-Dysfunction Associated Steatohepatitis with Liver Fibrosis (13:55 – 20:00).
5. Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections (the Balance Trial) (20:00 – 23:30).

And for the Good Stuff:

• Toronto Star Santa Claus Fund, Calgary Food Bank, Epilepsy Canada (23:30 – 24:51).

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners!

We are back this week with a special podcast episode! Dr. Mike Fralick sits down with Dr. David-Dan Nguyen, a Urology Resident at the University of Toronto, to chat about his recent study, "Payments by Drug and Medical Device Manufacturers to US Peer Reviewers of Major Medical Journals", that has been recently published in JAMA.

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Dr. Zahra Merali (Host) sits down with Dr. Shaima Kaka (Internal Medicine resident) to discuss her first place winning clinical vignette (oral case report) from the Canadian Conference of Medicine Annual Meeting 2024.

Resources: Diabetic Striatopathy: An Updated Overview

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners!

We are back today with a solo episode with Dr. John Fralick!

This week, he will discuss a paper exploring whether Renin-Angiotensin System Inhibitors should be held before major non-cardiac surgery. Here we go!

1. Continuation versus Discontinuation of Renin-Angiotensin System Inhibitors Before Major Non-Cardiac Surgery: The Stop-or-Not Randomized Clinical Trial (0:00 – 6:16).

And for the Good Stuff:

• "Tweetorials" by Tony Breu (6:16 – 7:11).

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Dr. Laiya Carayannopoulos sits down with Nick Sanchez (MD student) to discuss his second place winning clinical vignette from the Canadian Society of Internal Medicine Annual Meeting 2024. 

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Dr. John Fralick sits down with Dr. Nicole Hawe, a first-year Internal Medicine resident at the University of British Columbia, to discuss her third place winning clinical vignette from the Canadian Society of Internal Medicine Annual Meeting 2024.

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners!

We are back today with our Classic Rapid Fire Podcast!

This week, Dr. Mike Fralick and special guest, Dr. Laiya Carayannopoulos from the Intern at Work Podcast and our Medicine Pods collaboration, discuss two recent papers exploring oxygenation in acute respiratory failure and the use of ablation versus anti-arrhythmic medication for ventricular tachycardia. Two papers, here we go!

1. High-Flow Nasal Oxygen vs Noninvasive Ventilation in Patients with Acute Respiratory Failure: The RENOVATE Randomized Clinical Trial (0:00 – 14:45).
2. Catheter Ablation or Antiarrhythmic Drugs for Ventricular Tachycardia (14:45 – 22:55).

And for the Good Stuff:

• Medicine Pods! (22:55 – 23:51).
• Sign-up to our mailing list to receive link to attend the Royal College Epidemiology Crash Course hosted by Dr. Mike Fralick

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners!

We are back today with our Classic Rapid Fire Podcast!

This week, Drs. Mike and John Fralick discuss two recent papers - whether aspirin should be held in patients with stable coronary artery disease and drug-eluting stents and the role of semaglutide in patients with obesity and knee osteoarthritis. Two papers, here we go!

1. Aspirin Monotherapy vs. No Antiplatelet Therapy in Stable Patients With Coronary Stents Undergoing Low-to-Intermediate Risk Noncardiac Surgery (0:00 – 10:15).
2. Once-Weekly Semaglutide in Persons with Obesity and Knee Osteoarthritis (10:15 – 22:50).

And for the Good Stuff:

• "I'm making money from my terrible paintings" (22:50 – 23:25).
• Squid Game Season Two (23:25 – 24:43)

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners!

We are back today with a solo episode with Dr. John Fralick!

This week, he will discuss a paper exploring infliximab versus cyclophosphamide for the treatment of severe Behçet's Syndrome. Here we go!

1. Infliximab versus Cyclophosphamide for Severe Behçet's Syndrome (0:00 – 5:15).

And for the Good Stuff:

• Bob Ross and Painting (5:15 – 6:28).

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners!

We are back today with a solo episode with Dr. Mike Fralick!

This week, he will discuss a paper exploring the role of intravenous thrombolytic therapy in patients with minor ischemic stroke and intracranial vessel occlusion. Here we go!

1. Tenecteplase versus standard of care for minor ischaemic stroke with proven occlusion (TEMPO-2): a randomised, open-label, phase 3 superiority trial (0:00 – 6:18).

And for the Good Stuff:

• Trial Files (6:18 – 7:59).

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners!

We are back this week with a special podcast episode! Dr. Mike Fralick sits down with Dr. Amy Yu, a Stroke Neurologist, Clinician-Scientist, and Associate Professor of Medicine at the University of Toronto and Sunnybrook Hospital, to chat about her hot-off-the press publication - Population-Level Screening for Diabetes and Dyslipidemia After Pregnancies Complicated by Hypertension or Diabetes!

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners!

We are back today with our Classic Rapid Fire Podcast!

This week, Drs. Mike and John Fralick discuss two recent papers - the role of continuous glucose monitoring for diabetes management in hospital and the benefit of tirzepatide in patients with heart failure with preserved ejection fraction and obesity. Two papers, here we go!

1. Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity (0:00 – 11:26).
2. DIATEC: A Randomized Controlled Trial (11:26 – 19:56).

And for the Good Stuff:

• Surgeons successfully transplant genetically edited pig kidney into U.S. man (19:56 – 20:55).
• Diabetes Trial Files (20:55 – 22:25)

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. Mike Fralick. This week, he will discuss a paper exploring endovascular treatment (EVT) for acute ischemic stroke due to medium-vessel occlusion. Here we go!

• Endovascular Treatment of Stroke Due to Medium-Vessel Occlusion (0:00 – 6:02).

This episode is sponsored by Northern Ontario Resident Streamlined Training and Reimbursement Program (NORSTAR). Check out details here!

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners! We are back today with our Classic Rapid Fire Podcast! This week, Drs. Mike and John Fralick discuss two recent papers examining the effect of glucagon-like peptide-1 receptor agonists (GLP1's) on patients living with Parkinson’s disease. Two papers, here we go!

1. Trial of Lixisenatide in Early Parkinson's Disease (0:00 – 10:24).
2. Exenatide once a week versus placebo as a potential disease-modifying treatment for people with Parkinson's disease (10:25 – 17:40).

And for the Good Stuff:

• Port Blandford artist creates portraits from Scotch tape (17:41 – 18:33).
• Rheumatology for the Royal College podcast (18:34 – 19:42).

This episode is sponsored by Northern Ontario Resident Streamlined Training and Reimbursement Program (NORSTAR). Check out details here!

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners!

We are back this week with a special podcast episode! Dr. Mike Fralick sits down with Dr. Jeffrey Carson, Distinguished Professor of Medicine at the Rutgers Robert Wood Johnson Medical School and Provost at Rutgers University, to chat about his recent publication - Restrictive versus Liberal Transfusion in Myocardial Infarction — A Patient-Level Meta-Analysis. Here we go!

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners! In this throwback episode, Drs. Mike and John Fralick chat about five important research studies published in 2023:

1. Hydrocortisone in Severe Community-Acquired Pneumonia (0:00 – 5:39).
2. Tirzepatide vs Insulin Lispro Added to Basal Insulin in Type 2 Diabetes (5:40 – 8:48).
3. Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes (8:49 – 12:29).
4. Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection (12:30 – 17:49).
5. Early versus Later Anticoagulation for Stroke with Atrial Fibrillation (17:50 – 23:38).

And for the Good Stuff:

• The Beckham docuseries on Netflix (23:39 – 24:15)
• Upside Drinks (24:16 – 26:04).

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners! We are back today with our Classic Rapid Fire Podcast! This week, Dr. John Fralick and guest host Dr. Chunpeng Nie discuss two recent papers: resmetirom for the treatment of Nonalcoholic Steatohepatitis (NASH)—now known as Metabolic Dysfunction-Associated Steatohepatitis (MASH)—with liver fibrosis, and the effect of a Mediterranean diet on disease activity, inflammation, and the gut microbiome in patients with ulcerative colitis. Two papers, here we go!

1. A Phase 3, Randomized, Controlled Trial of Resmetirom in NASH with Liver Fibrosis (0:00 – 10:17)
2. A Mediterranean Diet Pattern Improves Intestinal Inflammation Concomitant with Reshaping of the Bacteriome in Ulcerative Colitis: A Randomised Controlled Trial (10:18– 15:45)

And for the Good Stuff:

• Shoutout to all the MTU teams supporting their R1's! (15:46 – 16:20).
• For the 1st time in Canada, surgeons put teeth in patients' eyes to restore sight (16:21 – 17:56)

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the role of high-dose Vitamin D therapy in reducing disease activity in patients with clinically isolated syndrome (CIS) typical of multiple sclerosis (MS). Here we go!

1. High-Dose Vitamin D in Clinically Isolated Syndrome Typical of Multiple Sclerosis: The D-Lay MS Trial (0:00 – 7:35).

Announcements (7:36 – 9:15):

• Canadian physicians, 2025 CMPA Council elections are underway in Alberta and Ontario! View the candidates and cast your ballot here.
• Check out Dr. Yatin Chada's podcast, beyondMD!

And we've launched qMonthly, a monthly blog highlighting headliners and hidden gem trials published each month. Check it out here!

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners! We are back today with a special Rapid Fire Podcast! This week, Drs. Mike and John Fralick discuss top papers from the 2025  American College of Cardiology (ACC) Annual Scientific Session. Hot off the presses, here we go!

1. Extended Reduced-Dose Apixaban for Cancer-Associated Venous Thromboembolism (0:00 - 5:55)
2. Dapagliflozin in Patients Undergoing Transcatheter Aortic-Valve Implantation (DapaTAVI) (5:56 - 9:51)
3. Oral Semaglutide and Cardiovascular Outcomes in High-Risk Type 2 Diabetes (9:52 - 14:04)
4. Semaglutide and walking capacity in people with symptomatic peripheral artery disease and type 2 diabetes (STRIDE) (14:05 - 18:36)

The Good Stuff:

• The Studio TV series on Apple (18:37 - 19:11)
• Cardiology Trial Files (19:12 - 20:40)

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. John Fralick. This week, he discusses a recently published trial examining liberal fluid intake vs. fluid restriction in chronic heart failure. Here we go!

1. Liberal fluid intake versus fluid restriction in chronic heart failure: a randomized clinical trial (0:00 – 4:20).

And for the Good Stuff:

• starpowerdrummer on YouTube (4:21 – 5:20).

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table listeners! To kick off the new year we have a very special episode, discussing what is known and what is not known about COVID-19 and pregnancy. Our guest is Dr. Verena (Vreni) Kuret She is the section head of the Maternal Fetal Medicine program in the Department of Obstetrics and Gynecology ...

The post Episode 21 – COVID-19 and Pregnancy with Dr. Kuret appeared first on Healthy Debate.

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Welcome back Rounds Table Listeners! Today we are back with a throwback to our interview with Dr. Robbie Goldstein early in the COVID-19 pandemic. Back in April, we interviewed Dr. Robbie Goldstein to find out how Mass General Hospital (MGH) in Boston has prepared, and adapted, to a massive influx of patients with COVID-19. Dr. ...

The post TBT – Dr. Robbie Goldstein on COVID-19 appeared first on Healthy Debate.

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This Week: Travis and Amol want you to: 1. Recognize IL-25 levels are good predictors of steroid-responsiveness in asthma. 2. Understand that the majority of patients who undergo elective percutaneous coronary intervention for stable angina are misinformed about its benefits. Continuing Medical Education Internists can receive 0.5 hours of Continuing Medical Education credit for each podcast ...

The post Unintended Puns: Predicting Steroid Response in Asthma and Patient Perceptions of PCI appeared first on Healthy Debate.

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Originally Aired September 10, 2014: Simvastatin in Secondary Progressive Multiple Sclerosis and Communicating With Patients About Risk Rebecca and Amol want you to: 1. Recognize that simvastatin reduces the rate of whole brain atrophy in secondary progressive MS, which may be a promising new use for statins. 2. Understand that effective strategies to communicate risk include: Using ...

The post 100% Bullish: Simvastatin in MS, Communicating Risk appeared first on Healthy Debate.

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Implementation of a Handoff Program in Pediatric Hospitals and Treating Depression in Cancer Patients Nathan and Amol want you to: 1.Recognize that a standardized handoff program reduced medical errors in academic pediatric hospitals. 2. Appreciate that a targeted program to treat depression in cancer patients was more effective than usual care. Continuing Medical Education Internists can ...

The post Dubious Acronyms: Handoff Quality and Treating Depression in Cancer Patients appeared first on Healthy Debate.

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This Week: Baseline cardiovascular risk calculators and hypertension treatment, and dual antiplatelet treatment after coronary stenting This week, Fahad and Amol want you to understand that: 1. A cardiovascular risk calculator can predict the degree of treatment benefit that patients may derive  from blood pressure treatment. 2. There is limited evidence to recommend continuing dual antiplatelet therapy beyond ...

The post Getting Cardiovascular: Baseline Risk and Hypertension Treatment and Dual Antiplatelet Therapy in Coronary Stents appeared first on Healthy Debate.

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This week, Travis and Amol want you to recognize that: 1. Recognize whole exome sequencing is an important new method of identifying genetic mutations associated with disease. 2. Understand that the 4-year follow-up of the PROTECT AF study showed that left atrial appendage closure devices may be superior to warfarin in preventing strokes in patients with atrial ...

The post Value Judgments: Whole exome sequencing and left atrial appendage closure devices appeared first on Healthy Debate.

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Originally Aired September 24, 2014: Fecal Transplantation & Probiotics for C. difficile; Prone Positioning in ARDS; Steroids in COPD; Hospital Management of Diabetes. Fahad and Amol want you to gain familiarity with a number of major studies in hospital medicine published in 2013. 1. Fecal transplantation is effective for recurrent C. difficile infection. 2. Probiotics are ...

The post Best of Hospital Medicine 2013 Part I appeared first on Healthy Debate.

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Originally Aired October 1, 2014: Blood Transfusions in Upper GI Bleeding, Aspirin in DVT prophylaxis, Vasopression and Steroids in Cardiac Arrest, MRSA Decolonization, Fluid and Sodium Restriction in Heart Failure Fahad and Amol want you to gain familiarity with a number of major new studies in hospital medicine published in 2013. Continuing Medical Education Internists can ...

The post Best of Hospital Medicine 2013 Part II appeared first on Healthy Debate.

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Neighbourhood Disadvantage and 30-day Rehospitalization; Teixobactin – a Novel Antibiotic Reena and Amol want you to understand the following: 1. Neighbourhood disadvantage was associated with an increased risk of readmission similar to the presence of chronic diseases like COPD. 2. Teixobactin is a new antibiotic with activity against gram positive organisms that was discovered using ...

The post From SES to Soil: Neighbourhood Disadvantage and A Groundbreaking New Antibiotic appeared first on Healthy Debate.

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Eosinophilic esophagitis Samir and Amol want you to understand the following: 1. Eosinophilic esophagitis is an important and under-recognized clinical condition that causes significant symptoms and is very treatable. 2. Endoscopy, and particularly duodenoscopy, is an important potential source of infection transmission. 3. The rise of outpatient endoscopy clinics requires the development of an appropriate remuneration, regulatory, ...

The post Special Gastroenterology Edition with Dr. Samir Grover, Gastro-naut appeared first on Healthy Debate.

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Factor XI Antisense Oligonucleotides for Post-operative VTE and Intra-arterial Treatment for Stroke Nathan and Amol want you to understand the following: 1. Factor XI is a promising treatment target for preventing VTE, with a recent study showing that an antisense oligonucleotide was more effective in reducing VTE and had less associated bleeding than enoxaparin. 2. Intra-arterial ...

The post These are not real stock tips: Post-op DVT Prophylaxis and Intra-arterial Treatment of Stroke appeared first on Healthy Debate.

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Originally aired July 2, 2014: Cryptogenic Stroke and Atrial Fibrillation, Naloxegol for Opioid-Induced Constipation Fahad and Amol want you to: 1. Appreciate the importance of subclinical atrial fibrillation in cryptogenic stroke and consider longer monitoring to detect it. 2. Recognize Naloxegol as a targeted therapy for opioid-induced constipation that is more effective than placebo but its effectiveness has not been compared directly ...

The post Getting “Travis-y”: Stroke and AFib, Naloxegol for Opioid Constipation appeared first on Healthy Debate.

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Effects of participation in the National Surgical Quality Improvement Program and Prednisone in Community Acquired Pneumonia Nathan and Amol want you to understand the following: 1. Participation in the National Surgical Quality Improvement Program has not appeared to improve overall patient outcomes or cost. 2. Adjunct prednisone treatment in community acquired pneumonia reduces time to clinical ...

The post The Royal We: Effects of Participation in NSQIP, Steroids for Pneumonia appeared first on Healthy Debate.

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The CHIPS trial of Hypertension in Pregnancy and TIPPS trial of Thrombophilia in Pregnancy Janice and Amol want you to understand the following: 1. Tight blood pressure control in pregnancy does not affect fetal outcomes in pregnancy compared with loose blood pressure control. The only difference in maternal outcomes is a reduced risk of severe hypertension ...

The post Obstetrical Medicine Special: Hypertension and Thrombophilia in Pregnancy appeared first on Healthy Debate.

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VOICE: Tenofovir and Emtricitabine for HIV pre-exposure prophylaxis in African women and SARAH: Hand exercises in Rheumatoid Arthritis Fahad and Amol want you to understand the following: 1. Pre-exposure prophylaxis was not effective in a population of African women. Medication adherence was apparently excellent based on self-report and pill counting, however serum drug levels demonstrated that it ...

The post SARAH’s VOICE: Pre-exposure prophylaxis in HIV and exercise for the rheumatoid hand appeared first on Healthy Debate.

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Originally aired March 11, 2014: obesity, palliative care, hepatitis c Amol, Fahad, and Travis want you to: 1. Understand trends in obesity prevalence in adults and children. 2. Appreciate the effect of early palliative care on quality of life in patients with advanced cancer. 3. Recognize new therapeutic options in chronic Hepatitis C infection and their associated cost ...

The post We turned one! “Too rich for my blood: Obesity, palliative care, hepatitis c” appeared first on Healthy Debate.

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This week: New studies of PCSK9 inhibitors for lipid lowering and a randomized controlled trial of early peanut exposure to prevent allergy Fahad and Amol want you to understand the following: 1. PCSK9 inhibitors are new cholesterol-lowering monoclonal antibodies that have been shown to reduce LDL beyond standard therapy with statins and have been associated with reduced ...

The post Peanut Placebo, Nocebo, PCSK9: Lipid lowering and peanut allergy appeared first on Healthy Debate.

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This week: The TITRE2 trial about hemoglobin transfusion strategies after cardiac surgery and the RETRACE study about intracranial bleeding in patients on warfarin. Nathan and Amol want you to understand the following: 1. In cardiac surgery patients, a restrictive transfusion strategy was no different than liberal transfusion in terms of combined clinical outcomes of infectious and vascular events ...

The post All About Bleeding: Transfusion targets after cardiac surgery and intracranial bleeding on warfarin appeared first on Healthy Debate.

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Originally aired September 3, 2014: Perioperative AFib and Long-Term Risk of Ischemic Stroke; Paracetamol not more effective than placebo in acute low back pain Nathan and Amol want you to: 1. Understand that perioperative atrial fibrillation is associated with increased long-term risk of ischemic stroke. 2. Recognize that a high quality Randomized Controlled Trial demonstrates that paracetamol is ...

The post Replay: We’re Back (pain)! Perioperative Atrial Fibrillation, Paracetamol and back pain appeared first on Healthy Debate.

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This week: Empiric antibiotic choices for community acquired pnuemonia and clindamycin versus trimethoprim-sulfamethoxazole for skin and soft tissue infections. Fahad and Amol want you to understand the following: 1. A large, high quality RCT showed that there was no significant difference between an empiric treatment strategy of beta-lactam vs beta-lactam plus macrolide vs respiratory fluoroquinolone for the ...

The post The Antibiotics Jam: Community Acquired Pneumonia and Skin Infections appeared first on Healthy Debate.

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This week: A Randomized Controlled Trial of Resident Call Schedules in the ICU and The Natural History of Benign Thyroid Nodules. Nathan and Amol want you to understand the following: 1. There was no significant difference between three different call schedules in the ICU in terms of resident sleepiness or patient outcomes. 2. Benign thyroid nodules are ...

The post Take me to the Bank: Resident call schedules in the ICU and Thyroid Nodules appeared first on Healthy Debate.

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Effects of participation in the National Surgical Quality Improvement Program and Prednisone in Community Acquired Pneumonia Nathan and Amol want you to understand the following: 1. Participation in the National Surgical Quality Improvement Program has not appeared to improve overall patient outcomes or cost. 2. Adjunct prednisone treatment in community acquired pneumonia reduces time to clinical ...

The post Replay-The Royal We: Effects of Participation in NSQIP, Steroids for Pneumonia appeared first on Healthy Debate.

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This week: The MARQUIS study of interventions to reduce medication errors in hospital, super-utilizer patients, and the potential of community health workers for population health and medical education. Amol and Shail want you to understand the following: 1. Medication errors are an important problem in hospital and a multi-faceted intervention can be effective in addressing this issue. 2. ...

The post What we loved at SGIM 2015: Medication Safety, Super-Utilizers, and Community Health Workers appeared first on Healthy Debate.

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Amol and Nathan want you to understand the following: 1. A large randomized evaulation of a quality improvement intervention demonstrated a modest but significant reduction in rates of cesarean-section in Quebec. 2. A large double-blind randomized-controlled-trial of over 1100 patients showed that pentoxifylline is not beneficial in the treatment of alcoholic hepatitis and prednisolone may have mild ...

The post A Hippocratic Dilemma: Reducing rates of c-sections and prednisolone vs. pentoxifylline for alcoholic hepatitis. appeared first on Healthy Debate.

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Originally Aired Jan 30: Eosinophilic esophagitis, outbreaks associated with duodenoscopy, and the rise of private endoscopy clinics Samir and Amol want you to understand the following: 1. Eosinophilic esophagitis is an important and under-recognized clinical condition that causes significant symptoms and is very treatable. 2. Endoscopy, and particularly duodenoscopy, is an important potential source of infection transmission. ...

The post Re-Play: Gastroenterology Edition with Dr. Samir Grover, Gastro-naut appeared first on Healthy Debate.

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Amol and Janice want you to understand the following: 1. Several RCTs and observational studies suggest that Transcatheter Aortic Valve Replacement reduces mortality and improves symptoms in frail, elderly patients. 2. A historical analysis demonstrates that the sugar industry had heavy influence in setting national dental research priorities in the 1970s, which is relevant for industry relations ...

The post The Sweet Truth: Transcatheter Aortic Valve Replacements and Sugar Industry Influence on Research Priorities appeared first on Healthy Debate.

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Amol and Fahad want you to understand the following: 1. There are dramatic hospital-level variations in the care of extremely pre-term infants. 2. A randomized trial showed that an electronic alert to identify hospital patients with acute kidney injury was not effective in improving patient outcomes. Continuing Medical Education Internists can receive 0.5 hours of Continuing Medical ...

The post Lifelong Learning: Variations in Care of Pre-term Infants and Electronic Alerts for Acute Kidney Injury appeared first on Healthy Debate.

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Amol and Nathan want you to understand the following: 1. A short duration (4 days) of antibiotics for intra-abdominal sepsis was equivalent to a longer duration (approx. 8 days) of antibiotics for intra-abdominal sepsis after an appropriate source control procedure. 2. A population-based cohort study of elderly patients showed that lipid lowering therapy for primary prevention was ...

The post On Our Soapbox: Antibiotics in intraabdominal sepsis and lipid therapy in the elderly appeared first on Healthy Debate.

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Amol and Reena want you to understand the following: 1. When added to moderate dose statin, the IMPROVE-IT randomized trial showed that ezetimibe improved clinical outcomes in patients after acute coronary syndrome. 2. A network meta-analysis showed that no blood pressure lowering therapy improved mortality in patients with diabetes and chronic kidney disease. The combination of ACE-inhibitors and ...

The post Debatable Landmarks: Ezetimibe and clinical outcomes, BP lowering in diabetes and kidney disease appeared first on Healthy Debate.

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Originally Published December 5, 2014: Travis and Amol want you to recognize that: 1. Recognize whole exome sequencing is an important new method of identifying genetic mutations associated with disease. 2. Understand that the 4-year follow-up of the PROTECT AF study showed that left atrial appendage closure devices may be superior to warfarin in preventing strokes in patients ...

The post Repeat: Value Judgments – Whole exome sequencing and left atrial appendage closure devices appeared first on Healthy Debate.

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Amol wants you to: 1. Consider how the evidence helps us decide whether to prescribe a patient warfarin or a novel oral anticoagulant for stroke prevention in atrial fibrillation. Continuing Medical Education Internists can receive 0.5 hours of Continuing Medical Education credit for each podcast they listen to through the Canadian Society of Internal Medicine (MOC Category 1) ...

The post Flying Solo: Warfarin vs. New Oral Anticoagulants, what does the evidence say? appeared first on Healthy Debate.

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Fahad and Amol want you to recognize that: 1. Idarucizumab as an agent that specifically reverses the hemostatic effects of dabigatran.  2. A post-hoc analysis of the ROCKET-AF study showed that digoxin is associated with increased mortality in patients with atrial fibrillation. The papers Idaracizumab for Dabigatran reversal. Digoxin use and mortality in ROCKET-AF. Good stuff http://www.smacc.net.au/about-us/welcome/ http://emupdates.com/wp-content/uploads/2015/06/Strayer-Opioid-Misuse-SMACC-Slideset.pdf ...

The post Season Finale: Dabigatran Reversal and Digoxin Mortality appeared first on Healthy Debate.

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Aired April 23: Empiric antibiotic choices for community acquired pnuemonia and clindamycin versus trimethoprim-sulfamethoxazole for skin and soft tissue infections. Fahad and Amol want you to understand the following: 1. A large, high quality RCT showed that there was no significant difference between an empiric treatment strategy of beta-lactam vs beta-lactam plus macrolide vs respiratory fluoroquinolone for ...

The post Summer Replay: Community Acquired Pneumonia and Skin Infections appeared first on Healthy Debate.

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Amol and Nathan want you to understand the following: 1. A large randomized evaulation of a quality improvement intervention demonstrated a modest but significant reduction in rates of cesarean-section in Quebec. 2. A large double-blind randomized-controlled-trial of over 1100 patients showed that pentoxifylline is not beneficial in the treatment of alcoholic hepatitis and prednisolone may have mild ...

The post Summer Replay 2: Reducing c-sections and prednisolone vs. pentoxifylline for alcoholic hepatitis appeared first on Healthy Debate.

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Originally aired May 22, 2015. Amol and Janice want you to understand the following: 1. Several RCTs and observational studies suggest that Transcatheter Aortic Valve Replacement reduces mortality and improves symptoms in frail, elderly patients. 2. A historical analysis demonstrates that the sugar industry had heavy influence in setting national dental research priorities in the 1970s, which ...

The post Summer Replay 3: Transcatheter Aortic Valve Replacements and Sugar Industry Influence on Research Priorities appeared first on Healthy Debate.

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Amol and Reena want you to understand the following: 1. When added to moderate dose statin, the IMPROVE-IT randomized trial showed that ezetimibe improved clinical outcomes in patients after acute coronary syndrome. 2. A network meta-analysis showed that no blood pressure lowering therapy improved mortality in patients with diabetes and chronic kidney disease. The combination of ACE-inhibitors and ...

The post Summer Replay 4: Ezetimibe and clinical outcomes, BP lowering in diabetes and kidney disease appeared first on Healthy Debate.

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Season 2 of The Rounds Table kicks off next week. To get things started, here’s a short episode with ‘good stuff’ recommendations from our excellent new team: Jennifer Peng, Anthony Maher, and Annie Wang. Good Stuff Jennifer: http://www.theatlantic.com/health/archive/2014/11/the-dutch-village-where-everyone-has-dementia/382195/  Anthony: http://blogs.plos.org/globalhealth/2013/11/jojewell2/?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+plos%2Fblogs%2Fblogosphere+%28Blogs+-+Blogosphere%29 Annie: http://freakonomics.com/2015/08/27/are-you-ready-for-a-glorious-sunset-a-new-freakonomics-radio-episode/  Music Credits (Creative Commons): In your Robotic Heart – Nicolai Heidlas https://soundcloud.com/nicolai-heidlas/in-your-robotic-heart Drive – Nicolai Heidlas https://soundcloud.com/nicolai-heidlas/drive-fresh-upbeat-pop-background-music Piano ...

The post Season 2 Promo: “Good Stuff” from our great new team appeared first on Healthy Debate.

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Amol and Fahad discuss: 1. A randomized controlled trial shows that a new approach to vagal maneuvers for supraventricular tachyarrhythmia was shown to be significantly more effective than traditional maneuvers. 2. A survey in California adolescents shows that there is an association between eCigarette use and subsequent tobacco use, raising concerns about a ‘gateway’ effect. The ...

The post New Beginnings: Better Vagal Maneuvers for Arrhythmias and eCigarettes in Adolescents appeared first on Healthy Debate.

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Nathan discusses a randomized trial about breast cancer screening that found that sending women information about both the risks and the benefits of breast cancer screening resulted in more women making an “informed choice” and fewer wanting to undergo screening mammography. Amol discusses the BRIDGE trial, which found that not bridging patients’ anticoagulation around the ...

The post Arithmetic Operations: Breast Cancer Screening Choices and Anticoagulation Bridging appeared first on Healthy Debate.

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It’s phototherapy without the need for electricity. Fahad discusses how filtered sunlight is found to be equivalent to conventional phototherapy in treating infants with elevated bilirubin levels. The film that filters the sunlight is low cost and low-tech, yet has the potential for global impact. Amol discusses using text messages to battle cardiovascular disease. Semi-personalized motivational ...

The post Brave New World: Filtered Sunlight for Jaundice and Text Messages for Healthy Lifestyle appeared first on Healthy Debate.

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The “broken heart syndrome” – not always caused by a broken heart? A multi-national, multi-centered observational study on takotsubo cardiomyopathy found that physical triggers are more common than emotional triggers, patients present predominantly with chest pain, ECG changes, and troponin elevation. The study also generated surprising hypotheses about what medications have long-term benefit for these ...

The post What the Heart Wants: Takotsubo Cardiomyopathy and Cardiovascular Benefits of Empagliflozen appeared first on Healthy Debate.

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Amol and Janice, general internal medicine residents at the University of Toronto, discuss 2 recent studies that challenge 2 widely accepted medical practices. Does using acetaminophen to treat fever improve outcomes? A randomized control trial found that giving acetaminophen to critically ill patients did lower their fever, but did not affect the number of ICU ...

The post Questioning Convention: Acetaminophen for Fever and Calcium for Fractures appeared first on Healthy Debate.

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This week we are replaying one of our favourite old episodes, due to many of our team members being away at the Canadian Society of Internal Medicine Conference. Originally aired on April 17, 2015, Nathan and Amol want you to understand the following: 1. There was no significant difference between three different call schedules in ...

The post Replay: Resident Call Schedules in the ICU and Thyroid Nodules appeared first on Healthy Debate.

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Amol, general internal resident at the University of Toronto, and Janice, general internist at the Mount Sinai Hospital in Toronto, discuss 2 recent studies: Dying with dignity is not easy, especially in a highly charged environment like the Intensive Care Unit. Janice talks about a mixed methods study that examined the impact of soliciting and fulfilling ...

The post Wishes and Pills: Fulfilling Wishes for Dying Patients and Medications for Back Pain appeared first on Healthy Debate.

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Amol, general internal resident at the University of Toronto, and Raed Joundi, neurology resident at the University of Toronto, discuss 2 recent studies: Is early mobilization helpful for stroke patients? A randomized control trial showed that early aggressive rehabilitation for acute stroke patients resulted in worse outcomes. Amol and Raed speculate reasons behind this counter-intuitive ...

The post Brain Week: Early Rehab for Stroke and Drug Interaction Increases Bleeding in Brain appeared first on Healthy Debate.

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This week we are replaying one of our favourite episodes from earlier this season: Originally aired on October 3, 2015, Amol, general internal resident at the University of Toronto, and Fahad, Staff Internist at St. Michael’s Hospital in Toronto, discuss two papers. It’s phototherapy without the need for electricity. Fahad discusses how filtered sunlight is found to ...

The post Replay: Filtered Sunlight for Jaundice and Text Messages for Healthy Lifestyle appeared first on Healthy Debate.

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This week, Amol, general internal resident at the University of Toronto, and Reena, General Internist at St. Michael’s Hospital in Toronto, discuss two papers: Reena shares a large registry-based study that found adult patients with Type 2 Diabetes in Sweden had a 15% higher mortality rate than the general population. Amol and Reena wonder why this ...

The post Diabetes Week: Mortality in Diabetes and DPP-4 Inhibitors Compared to Sulfonylureas appeared first on Healthy Debate.

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Amol, general internal medicine resident at the University of Toronto, and Nathan, general surgery resident at the University of Toronto, discuss 2 recent studies: Does it matter which hospital patients return to after surgery? A large retrospective cohort study showed that when post-operative patients are re-admitted to the same hospital where they had their surgery, ...

The post Changing the Tune: Post-operative Readmission and Music as Perioperative Therapy appeared first on Healthy Debate.

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This week, Amol, resident in General Internal Medicine at University of Toronto, and Mike Fralick, chief medical resident at St. Michael’s Hospital in Toronto, talk about 2 blood pressure studies: A meta-analysis and systematic review found that more intensive blood pressure lowering was associated with improved cardiovascular outcomes and albuminuria. Amol discusses the trade-offs of ...

The post The SPRINT to lower blood pressure appeared first on Healthy Debate.

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This week we are replaying our first episode of the season. Originally aired on September 18, 2015, Amol and Fahad discuss: 1. A randomized controlled trial shows that a new approach to vagal maneuvers for supraventricular tachyarrhythmia was shown to be significantly more effective than traditional maneuvers. 2. A survey in California adolescents shows that there is ...

The post Replay: Better Vagal Maneuvers for Arrhythmias and eCigarettes in Adolescents appeared first on Healthy Debate.

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This week, Amol, general internal medicine resident at the University of Toronto, and Fahad, general internist at St. Michael’s hospital in Toronto, discuss two recent papers: Fahad and colleagues recently published a study in JAMA that looks at severe adult undernutrition in low and middle income countries. Using 20-year health survey data collected by USAID, ...

The post Fahad’s Work and Fahad Gets Worked Up: Prevalence of severely underweight women and peripheral arterial disease appeared first on Healthy Debate.

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Happy new year! In our first episode of 2016, Amol, general internal medicine resident at the University of Toronto, talk about his 10 favourite papers of 2015. Rate us on iTunes! Follow us on Twitter @roundstable. The Papers 1. Teixobactin, a new antibiotic:  http://www.nature.com/nature/journal/v517/n7535/full/nature14098.html 2. Modified Valsalva manoeuvre: http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2815%2961485-4/abstract 3. Prednisolone or pentoxifylline for alcoholic ...

The post Amol’s 10 Favourite Papers of 2015 appeared first on Healthy Debate.

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Amol, general internal medicine resident at the University of Toronto, and Reena, staff physician in internal medicine at St. Michael’s hospital, discuss 2 recent papers: Opioid prescription is an increasing public health crisis. A retrospective cohort study found that patients who experience non-fatal opioid overdose almost always get re-prescribed opioids at large doses a month ...

The post The Upbeat Episode: Opioid Prescription and High Sensitivity Troponin Assay appeared first on Healthy Debate.