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The Energy Balance Podcast (Jay Feldman Wellness)

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Pub. DateTitleDuration
13 Jan 2022Ep. 79: Hyperthyroidism, Collagen Alternatives, and Forcing Mitochondrial Respiration (Q & A)01:10:54
In this episode we discuss:
  • Whether it’s beneficial to force increased mitochondrial respiration with supplements

  • How to determine the ideal amount of pro-metabolic supplements to take 

  • What to do if you react poorly to collagen or gelatin protein powder

  • Whether food additives like carrageenan, gums, nitrates, sorbates, MSG, microbial enzymes, cultures, and artificial colors are worth avoiding

  • Whether we need to be concerned about hyperthyroidism and whether hyperthyroidism can be caused by over-supplementing thyroid hormone

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-79-hyperthyroidism-collagen-alternatives-and-forcing-mitochondrial-respiration-q-a/ 

 

Timestamps:

2:39 – is it beneficial to “force” increased mitochondrial respiration and the oxidation of glucose

15:09 – alternatives to collagen or gelatin protein powder 

19:19 – which food additives are worth avoiding 

58:53 – whether hyperthyroidism is something we should be concerned about

 

04 Oct 2021Ep. 71: Weight Gain From Replenishing Glycogen & Calcium Sources Other Than Dairy (Q & A)00:44:49
In this episode we discuss:
  • How much weight gain can be attributed to increases in glycogen storage when adding in carbohydrates

  • At what point weight gain would be a sign of an underlying metabolic issue

  • The best ways to get calcium if you’re not eating dairy  

  • Potential ways to improve your tolerance to dairy

  • The best form of calcium to use as a calcium supplement 

  • Which calcium-containing vegetables might be worth including in your diet 

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-71-weight-gain-from-replenishing-glycogen-calcium-sources-other-than-dairy-q-a/ 

 

Timestamps:

3:13 – how much weight gain can be attributed to refilling glycogen

25:02 – calcium sources other than dairy

 

19 Nov 2024BV #4: Responding To Thomas Delauer, Ben Bikman on Insulin Resistance, and Layne Norton on Seed Oils02:07:18
In this episode we discuss:
  • What Layne Norton is missing regarding seed oils
  • What we think of Liver King’s steroid use and how this relates to fitness culture and unhealthy body image
  • Ben Bikman’s complete misapplication of a study regarding blood sugar and insulin resistance
  • Jay’s response to Thomas DeLauer regarding omega-3s and cod liver oil

 

 

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/

Danny's Telegram: https://t.me/dannyroddy

 

 

Timestamps:

0:00 – intro

0:28 – Andrew Huberman and Layne Norton on whether seed oils are inherently harmful

4:18 – why Layne Norton's "calories-only" view is flawed, as it ignores how the type of food actually affects our bodies

9:58 – whether animal studies are useful in nutritional research, or if only human randomized control trials (RTC) should be considered

15:57 – problematic assumptions and biases in nutritional research and how they can shape research outcomes

20:59 – why the reported health benefits of polyunsaturated fats in research are misleading and harmful

26:54 – the connection between chronic disease and polyunsaturated fats, and how focusing solely on calories relieves the food industry of responsibility for health outcomes

31:43 – Liver King's self-esteem, body image struggles, steroid use, health risks, and why his apology was commendable

41:36 – why cultural standards for physical appearances are unrealistic, unhealthy, and can lead to conflating steroid-enhanced bodies for genuine health

51:12 – health risks associated with steroid-use and having too much muscle mass

1:00:34 – Thomas Delauer and Derek from moreplatesmoredates discuss omega-3s

1:06:21 – whether the antioxidants in fish oil are worth the damage caused by lipid peroxidation

1:10:54 – whether cod liver oil is any better than fish oil

1:17:11 – how to effectively hydrate your cells and the importance of getting enough salt

1:24:44 – why consuming a lot of plain water without electrolytes actually impairs hydration, contributing to increased swelling, increased stress, and impaired energy production

1:32:38 – the importance of getting adequate potassium in addition to salt intake

1:38:03 – factors that may increase your need for water

1:40:02 – what Ben Bikman misses when it comes to blood glucose and insulin resistance

1:48:15 – the true relationship between insulin and blood sugar regulation

1:54:30 – Ben Bikman misapplies this study: it does not support that carbohydrates cause insulin resistance

2:00:38 – creating content in the health sphere, choosing high quality foods, and the benefits of tracking food (using Cronometer or another similar app)

10 May 2024Ep. 115: LMHR & The Lipid Energy Model: Implications For Metabolism & Hormones00:55:30
In this episode we discuss:
  • Whether you should be concerned about high LDL or high cholesterol on a low-carb diet
  • The validity of the Lean Mass Hyper-Responder (LMHR) Phenotype and Lipid Energy Model proposed by Dave Feldman
  • The metabolic state that drives the Lipid Energy Model
  • How the "Lean Mass Hyper-Responder" and Lipid Energy Model support the Bioenergetic view of cardiovascular disease

 

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

 

Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/

 

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

 

The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/

 

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-115-lmhr-and-the-lipid-energy-model-implications-for-metabolism-and-hormones

 

Timestamps:

0:00 – intro

1:14 – what is the Lean Mass Hyper-Responder (LMHR) phenotype

3:33 – how the Lipid Energy Model challenges the mainstream dogmatic view linking high cholesterol levels to heart disease

6:33 – the protective effects of cholesterol and why it does not cause heart disease, despite being necessary for atherosclerosis

9:49 – the distinction between Lean Mass Hyper-Responders and those with high cholesterol levels in the context of metabolic dysfunction

15:10 – what is the Lipid Energy Model

22:10 – how the body adapts to a lack of carbohydrates, leading to elevated cholesterol levels

27:22 – the hormonal and metabolic state underlying the Lean Mass Hyper-Responder phenotype

32:21 – how adding carbohydrates lowers cholesterol levels in those who don't have metabolic dysfunction at a cellular level

37:11 – whether Lean Mass Hyper-Responders are at increased risk of cardiovascular disease

42:00 – why the Lean Mass Hyper-Responder phenotype isn't ideal: stress and low thyroid function

51:10 – the parallels between the lipid energy model and physiological insulin resistance

27 Apr 2020Ep. 5: Blood Sugar Part 2: Cravings, Anti-Fructose Misconceptions, and the Best Starch Sources01:06:38

In this episode we discuss:

  • ​How different types of carbohydrates affect our blood sugar
  • The benefits of fructose and why much of the anti-fructose research is misguided
  • The relationship between carbs, stress hormones, and how you feel
  • Which starchy foods are the healthiest and which we should avoid
  • ​The best way to eat starch for blood sugar regulation
  • What cravings and hunger can tell us about our energy balance
  • How to stop restriction, binging, and “carb addiction”

Sign up for the free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy/

    Click here to check out the show notes: https://jayfeldmanwellness.com/ep-5-blood-sugar-part-2-cravings-anti-fructose-misconceptions-and-the-best-starch-sources/
19 Apr 2021Ep. 54: Sugar, Candida Overgrowths, & Whether a Calorie Surplus is Required to Build Muscle (Q & A)00:55:46
In this episode we discuss:
  • Whether a calorie surplus is needed to build muscle

  • How you can build muscle and lose fat at the same time (without a calorie deficit)

  • How you can build muscle while being in an energy deficit and why this comes at a major cost

  • Whether eating sugar will cause candida overgrowths

  • Whether refined sugar affects candida or other overgrowths differently from “natural sugars”

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-54-sugar-candida-overgrowths-whether-a-calorie-surplus-is-required-to-build-muscle-q-a/ 

 

Timestamps:

2:53 – whether a calorie surplus is required for muscle building and whether muscle can be built or maintained in an energy deficit

24:47 – thriving vs. surviving in terms of maintaining muscle mass and losing fat

32:42 – does sugar cause candida overgrowth

 

26 May 2021Ep. 59: How to Increase Carbon Dioxide and Minimize Lactate (Oxygenation, Swelling, and pH Balance Part 4)00:48:41
In this episode we discuss:
  • The major problem with Wim Hoff breathing and an alternative that supports carbon dioxide production

  • Why using thyroid, caffeine, and other metabolic stimulants can increase or decrease carbon dioxide production depending on the context

  • Why burning carbs leads to more than a 50% increase in carbon dioxide production relative to fat-burning

  • How PUFA consumption decreases carbon dioxide production

  • The best carbohydrate sources to oppose stress and support carbon dioxide production

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-59-how-to-increase-carbon-dioxide-and-minimize-lactate-oxygenation-swelling-and-ph-balance-part-4/

 

Timestamps:

4:20 – energy and the structuring of water as the drivers of health and life and opposition of aging

19:05 – the role of excess lactate and a lack of CO2 in neuropathy and nerve damage in diabetes, glaucoma, and epilepsy

20:18 – how increasing mitochondrial respiration increases carbon dioxide and the importance of using carbohydrates as a fuel instead of fat when it comes to carbon dioxide production

23:16 – how PUFA consumption decreases carbon dioxide production

27:43 – how thyroid, caffeine, and B vitamins can increase carbon dioxide production

29:56 – the problem with Wim Hoff breathing and alternatives that increase carbon dioxide production, including bag breathing and Buteyko breathing

39:57 – carbohydrate sources to oppose stress and support carbon dioxide production

43:48 – other considerations regarding Buteyko, other breathing techniques, and the double-edged sword of prometabolic supplements

 

29 Jun 2020Ep. 14: Listening To Our Bodies & Taking Our Health Into Our Own Hands (Q & A)00:42:33
In this episode we discuss:
  • Why listening to our bodies and experimenting is key if we want to improve our health
  • The dangers of relying on gurus or authority figures for our health information (and what to do instead)
  • Why open-mindedness is necessary for learning and progress
  • The dangers of identifying with any eating paradigm or belief system
  • Why it’s okay to be wrong
Sign up for a free call here: https://jayfeldmanwellness.com/call   Sign up for the free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy/   Click here to check out the show notes: https://jayfeldmanwellness.com/ep-14-listening-to-our-bodies-taking-our-health-into-our-own-hands-q-a/
06 Apr 2020Ep. 0: Protecting Yourself From COVID-19 and How to Support Your Immune System01:41:33

In this episode we discuss:

  • The direct physiological effects of COVID-19 and what they mean for our health
  • ​How we can protect ourselves from these effects of COVID-19
  • The relationship between our metabolic health and our immune system
  • Why COVID-19 is not unique and why we shouldn’t treat it as ​if it is
  • Which treatments currently used for COVID-19 we may want to avoid
  • What we should eat and what supplements we can use to keep our immune system functioning at its best
  • Which things we may NOT want to do to “support our immune system” (like taking omega-3s, drinking tons of water, and fasting)

 

Sign up for the free Energy Balance Mini Course here: https://jayfeldmanwellness.com/energy/

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-0-protecting-yourself-from-covid-19-and-how-to-support-your-immune-system/

19 May 2021Ep. 58: Altitude, Panic Attacks, Swelling, Heart Failure, & More (Oxygenation, Swelling, and pH Balance Part 3)01:07:56
In this episode we discuss:
  • How insulin resistance and diabetes are symptoms of excess glycolysis and lactate production, and how metformin makes these conditions worse

  • How excess lactate production and a lack of CO2 causes altitude sickness and anxiety and panic attacks

  • The benefits of altitude and the surprising parallel effects of stormy weather

  • The problem with 100% oxygen ventilation in critical illnesses like severe COVID-19 infections and sepsis

  • How glycolytic metabolism and the swelling that results contributes to high blood pressure and heart failure

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-58-altitude-panic-attacks-swelling-heart-failure-and-more-oxygenation-swelling-and-ph-balance-part-3/

 

Timestamps:

3:40 – health conditions and situations where we see impaired oxygenation and swelling

8:54 – insulin resistance as a presentation of inhibited glucose oxidation, excess glycolysis, and lactate production, and why metformin makes this worse

21:16 – respiratory alkalosis in altitude sickness

36:28 – respiratory alkalosis in panic attacks/anxiety attacks and hyperventilation

41:09 – adaptation to altitude, the lactate paradox, and stormy weather

43:59 – the problem with 100% oxygen ventilation in acute respiratory distress syndrome (ARDS), including sepsis and respiratory illness like COVID-19, and the protective effects of CO2 in these situations

54:49 – how a lack of CO2 and excess lactate causes pulmonary edema, impaired ventilation, impaired heart contractility, reduced circulation, high blood pressure, mineral imbalances, and edema

 

06 May 2021Ep. 56: Carbon Dioxide As A Key To Raising Metabolism (Oxygenation, Swelling, and pH Balance Part 1)01:05:57
In this episode we discuss:
  • Why increasing carbon dioxide production is key if we want to increase our metabolism

  • Whether burning carbohydrates is the best way to raise carbon dioxide

  • How carbon dioxide interacts with our cellular protein structure to create structured water

  • Carbon dioxide’s role in circulation and preventing high blood pressure

  • How carbon dioxide reduces swelling and water retention

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-56-carbon-dioxide-as-a-key-to-raising-metabolism-oxygenation-swelling-and-ph-balance-part-1/

 

Timestamps:

2:46 – an introduction to the relevance of carbon dioxide (CO2)

6:35 – the role of carbon dioxide in respiration (The Bohr and Haldane Effects)

13:45 –carbon dioxide as a driver of our metabolism and the importance of carbohydrate oxidation for CO2 production

27:10 – carbon dioxide as the primary vasodilator

32:50 – carbon dioxide as an antioxidant that protects against reactive oxygen species and reactive nitrogen species

38:22 – carbon dioxide in the context of hormesis and its anti-hormetic effects

41:29 – the value of the context provided by the bioenergetic view

47:40 – carbon dioxide’s role in the structuring of the cell and creating structured water, as well as reducing swelling and water retention

 

15 Dec 2023Ep. 106: Omega-3s INCREASE Inflammation and Oxidative Stress01:18:04
In this episode we discuss:
  • Studies showing that fish oil and cod liver oil supplementation increase oxidative damage in humans, even in the triglyceride form alongside antioxidants 
  • Why omega-3s are harmful in both healthy and unhealthy humans 
  • The harmful metabolic and hormetic effects of omega-3s (and why omega-3s aren’t beneficial due to hormesis) 
  • The research showing that omega-3s do not improve chronic health conditions or mortality in humans 

 

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

 

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

 

 

Click here to check out the show notes: https:/jayfeldmanwellness.com/ep-106-omega-3s-increase-inflammation-and-oxidative-stress/

 

Timestamps:

0:00 – intro

1:26 – a summary of the harmful effects of omega-3 consumption in humans

9:14 – omega-3 consumption amplifies the damage from stress (including fasting)

17:08 – vitamin E does not protect against lipid peroxidation from fish oil consumption

20:06 – studies showing that increased omega-3 consumption (including fish oil and cod liver oil) in humans and other animals increases lipid peroxidation, even in triglyceride form

31:45 - how omega-3s triggers hormesis, and why this doesn’t make omega-3s beneficial

39:50 – the context of the omega-3 research and its application

42:57 – studies showing that omega-3 supplementation doesn’t improve chronic health conditions or reduce mortality in humans

07 Feb 2022Ep. 80: How Much Exercise Is Too Much From The Bioenergetic View? (Fitness vs. Health Part 1)01:15:53
In this episode we discuss:
  • The harmful effects of excess exercise

  • Why increasing exercise beyond moderate amounts is NOT effective for weight loss

  • The harmful effects of excessive endurance training on cardiovascular health

  • How excess exercise can drive degeneration and contribute to various health issues

  • How much exercise is “too much”

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-80-how-much-exercise-is-too-much-from-the-bioenergetic-view-fitness-vs-health-part-1/ 

 

Timestamps:

2:37 – framing the question of where health and fitness meet from the bioenergetic view

13:12 – how excess exercise can cause degeneration and contribute to various health conditions  

21:03 – what level of exercise is harmful for cardiovascular health 

29:55 – how the expensive tissue hypothesis applies to exercise 

45:14 – how excess exercise can steal energy from other areas of our physiology, and how this affects the calorie equation 

1:08:23 - can moderate-intensity endurance training for 25 minutes 3 days per week be too much?

 

06 Mar 2025Ep. 129: The Forgotten Source of Oxalates: Your Body’s OWN Production01:36:55
In this episode we discuss:  
  • How much oxalate your body produces and how it compares to the amount you consume in your diet
  • Whether you need to be concerned about vitamin C, hydroxyproline, and glycine converting to oxalates
  • How you can reduce the amount of oxalates your body produces
  • Which nutrients decrease oxalate production
  • How metabolic dysfunction affects oxalate production

 

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

 

The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/

 

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-129-the-forgotten-source-of-oxalates-your-bodys-own-production/

 

Timestamps:

0:00 – intro 

1:12 – overview of endogenous vs. exogenous oxalates 

5:46 – how much oxalate comes from endogenous production vs. diet 

9:14 – when endogenous oxalate production matters more than dietary oxalate 

15:03 – rare genetic disorders that cause excessive oxalate production: primary hyperoxaluria 

22:36 – the pathways in the liver that lead to oxalate production 

32:41 – other biochemical pathways involved in endogenous oxalate production 

41:19 – deranged metabolic function as a primary driver of glyoxal production and lipid peroxidation 

45:14 – the extent to which glycine and vitamin C contribute to endogenous oxalate formation 

48:00 – how much does hydroxyproline contribute to oxalate production? 

52:06 – the primary precursor to oxalate that’s often ignored (glyoxal) 

55:08 – how oxidative stress drives oxalate production and how antioxidants help 

1:01:20 – what causes the high oxalate levels seen in type 2 diabetes, obesity, cardiovascular disease, and non-alcoholic fatty liver disease (NAFLD)? 

1:11:16 – the protective effects of glycine in states of excess oxalate production 

1:15:54 – elevated stress hormones and gluconeogenesis increase oxalate production 

1:22:43 – nutrient deficiencies that contribute to oxalate issues (vitamin B1, vitamin B6, and zinc)

22 Dec 2021Ep. 78: Why Maximizing Energy Production and Minimizing Stress Is Optimal For Health (Hormesis Part 4)01:16:03
In this episode we discuss:
  • How you can induce mitochondrial biogenesis and uncoupling without stress

  • Why you want tighter mitochondrial coupling if you want to induce uncoupling in a healthy way

  • The difference between reactive oxygen species production in a high energy state versus a low energy state

  • How many supposedly hormetic interventions, like exercise, fasting, and ketogenic diets, can be beneficial despite the stress they cause rather than because of it

  • How the fact that we can’t avoid stress fits into the bioenergetic, anti-hormetic view

  • What anti-hormesis looks like in a practical sense

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-78-why-maximizing-energy-production-and-minimizing-stress-is-optimal-for-health-hormesis-part-4/ 

 

Timestamps:

3:22 – the difference between producing ROS in a high energy state compared to a low energy state  

9:38 – how ATP protects against oxidative stress

21:55 – how CO2 protects against oxidative stress

26:31 – how tighter mitochondrial coupling is better for inducing uncoupling

27:48 – the broader context of why we want to adapt to a high-energy, low-stress state 

33:28 – how exercise can be beneficial despite the stress it causes, rather than because of it

47:06 – how low-carb/ketogenic diets can be beneficial despite the stress they cause, rather than because of it

57:40 – what to expect when moving away from a hormetic approach 

1:02:16 – how the fact that we can’t avoid stress fits into the bioenergetic, anti-hormetic view 

1:03:39 – what anti-hormesis looks like in a practical sense

 

03 Sep 2021Ep. 69: Carb Deficiencies, Saturated Fat Intake, & The Best Diet For Fatty Liver (NAFLD Part 7)01:02:29
In this episode we discuss:
  • How carbohydrate deficiencies can drive fatty liver disease

  • The particular type of fat you’ll want to avoid if you have fatty liver disease

  • The optimal amount of protein, fat, and carbs for reversing fatty liver disease

  • The order of dietary adjustments for fatty liver disease and why this matters

  • Whether reducing fructose intake is necessary for treating or reversing fatty liver disease 

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-69-carb-deficiencies-saturated-fat-intake-the-best-diet-for-fatty-liver-nafld-part-7/ 

 

Timestamps:

3:38 – the importance of dietary protein and choline for fatty liver

14:41 – the best types of fats and how much of these fats to eat for fatty liver

28:30 – the ideal carbohydrate sources for reversing fatty liver and major considerations to keep in mind

40:43 – the importance of experimentation when implementing dietary changes

47:05 – why carbohydrates are so effective at opposing stress, increasing metabolism, and reducing oxidative stress

49:22 – the importance of nutrient density and particular micronutrients for fatty liver disease

52:56 – why it’s important to minimize alcohol intake in fatty liver disease and how to protect against the effects of alcohol on the liver

56:12 – how diet, lifestyle, and supplements fit together to create a holistic approach to treating or reversing fatty liver

 

07 Nov 2024Ep. 125: Wendy Sellens on Estrogen: What She Got Wrong00:57:59

In this episode we discuss:

  • Whether estrogen is just a reproductive hormone
  • Whether you need to be concerned about testosterone converting to estrogen
  • How you can have excess estrogen production even after menopause
  • The best way to use progesteron
  • Whether Calcium D-glucarate is effective for lowering estrogen

 

 

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

 

Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/

 

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

 

 

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-124-forget-about-cico-a-smarter-approach-to-fat-loss/

 

 

Timestamps:

0:00 – intro 

1:07 – our thoughts on Wendy Sellens’ recent interviews with the Strong Sistas (Ashley and Sarah Armstrong) 

6:30 – the importance of reviewing research with an open mind, avoiding any rigid or authoritative stance 

9:38 – whether all research should be rejected due to Rockefeller funding and whether Dr Ray Peat was “Rockefeller trained” 

15:47 – whether reproductive hormones affect only reproductive organs 

20:35 – how hormonal imbalances affect all areas of health—reproduction, digestion, edema, bloating, cancer risk, weight gain, brain health, bone health, and muscle growth 

23:38 – whether Dr Hobbins’ experiments proved that there are no receptors for reproductive hormones in non-reproductive organs 

26:51 – why Wendy’s claim—that the rise in estrogen during pregnancy is caused by exogenous compounds (phytoestrogens and xenoestrogens)—is incorrect 

29:29 – estrogen’s role as a growth-promoting hormone and how progesterone counterbalances it by promoting cellular differentiation 

35:47 – whether testosterone can be converted into estrogen 

36:52 – how you can have excess estrogen production even after menopause and problems with estrogen testing 

40:19 – body fat as a major source of estrogen 

44:33 – why Wendy’s claim that calcium D-glucarate increases estrogen is incorrect 

46:56 – the mechanism through which calcium D-glucarate effectively lowers estrogen levels 

50:28 – confounding variables that make it difficult to accurately interpret the results of breast thermography scans 

11 Jun 2021Ep. 61: Undereating, Fad Diets, and Discovering the Bioenergetic View (Our Health Journeys Part 1)01:35:09
In this episode we discuss:
  • Mike’s severe gut issues that led to dangerous weight loss and eventually surgery

  • Jay’s experience with undereating/anorexia and how this shaped his health journey

  • How doing everything we were “supposed to do” led to us feeling our worst

  • Our experiences following various diets (vegetarian, paleo, keto, intermittent fasting, low-fat, bodybuilding) and how we navigated through them

  • Our experiences with symptoms like cold hands and feet, insomnia, low energy, low libido, anxiety, depression, hair loss, joint pain, bloating, weight gain, allergies, histamine intolerance, psoriasis, and viral and fungal issues

  • What led us to Ray Peat and the bioenergetic view

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-61-undereating-fad-diets-and-discovering-the-bioenergetic-view-our-health-journeys-part-1/

 

Timestamps:

3:40 – why we decided to share our stories

6:54 – the beginning of Mike’s health journey and his experience with severe gut issues, the conventional medical system, and surgery

41:24 – the earlier parts of Jay’s health journey and his experience with severe undereating, binging, and conventional nutrition information

1:06:23 – when we began to question mainstream ideas and low-carb

1:22:05 – our introduction to Ray Peat and the bioenergetic view through Danny Roddy

1:25:26 – our initial pro-metabolic/paleo combo diet

 

21 Sep 2023Ep. 102: How Western Culture & Mainstream Medicine Keep Us Sick01:04:49
In this episode we discuss:
  • Why culture matters and how we can effectively navigate it
  • The impact of the diet culture and the “eat less exercise more” paradigm
  • How Western culture blames the individual for their poor health and the toll that this takes 
  • The problems with excess work, time indoors, and sedentarism
  • How the modern medical system takes away your capacity to improve your health
  • Why the alternative health sphere can be just as problematic as mainstream medicine 

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

 

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-102-how-western-culture-mainstream-medicine-keep-us-sick/

 

Timestamps:

0:00 – why we’re discussing culture and our concerns with the culture in the US and the relationship between culture and health  

6:05 – frames through which we can view culture and the importance of Maslow’s hierarchy of needs

13:00 – how western culture degrades health: diet culture and the food industry

27:43 – how western culture degrades health: excess work, time indoors, and sedentarism 

34:30 – how easily we can become numb to the effects of our culture or environment 

38:07 – the broken modern medical system and the problems with the allopathic, symptom management model 

48:21 – problems with the alternative health sphere  

27 Jun 2023Ep. 93: How Cortisol Affects Your Mitochondria & Acute vs. Chronic Stress (Stress & Mitochondria Part 1)01:16:29
In this episode we discuss:
  • Why stress is not your friend

  • The effects of cortisol on your mitochondria

  • Hans Selye’s general adaptation syndrome

  • How cortisol causes mitochondrial dysfunction, heart disease, insulin resistance, autoimmunity, allergies & hypersensitivity, mineral imbalances, and cancer metabolism

  • Why acute stress does not lead to improved health via hormesis

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-93-how-cortisol-affects-your-mitochondria-acute-vs-chronic-stress-stress-mitochondria-part-1-ep-93/ 

 

Timestamps:

3:00 – an introduction to the paper: mitochondria as key components of the stress response   

4:03 – Hans Selye’s general adaptation syndrome and the process of stress in relation to energy balance  

23:30 – the 3 main effects of the stress hormones in the acute stress response and the cost to this response 

31:48 – long-term glucocorticoid exposure causes insulin resistance and the protective effects of high blood sugar in certain contexts 

34:04 – how long-term stress causes degeneration 

34:55 – functions of the mitochondria 

38:54 – mitochondria upregulate energy production in response to stress 

41:06 – the short-term vs. long-term effects of the glucocorticoids (cortisol)

44:03 – how stress causes hormetic adaptations and how the hormetic pathways cause degeneration over time

50:30 – how mitochondria respond to excess stress and how this relates to fat gain

59:04 – how chronic stress and exposure to cortisol causes impaired energy production, degeneration, immunosuppression & autoimmunity, mineral imbalance, swelling, allergies & hypersensitivity, and cancer metabolism

13 Feb 2024Ep. 109: Chris Palmer's “Brain Energy”, Type 1 Diabetes, and Low-Fat Diets For Weight Loss (Q & A)01:00:09
In this episode we discuss:
  • Our thoughts on Chris Palmer’s “Brain Energy” theory of mental health
  • Why low carb diets are not the solution for anxiety and depression and what to do instead
  • What most people miss when it comes to weight loss and why we shouldn’t focus on fat-burning
  • Strategies to optimally manage blood sugar for Type 1 Diabetes
  • Whether we should lower our fat intake to lose weight 

 

Sign up for the Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide 

 

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

 

Click here to check out the show notes: https:/jayfeldmanwellness.com/ep-109-chris-palmers-brain-energy-type-1-diabetes-and-low-fat-diets-for-weight-loss-qa

 

Timestamps:

0:00 – intro

1:19 – our take on Chris Palmer's “Brain Energy” theory of mental health disorders

5:04 – challenging the misconception of a separation between the brain and body

8:03 – why low-carb, ketogenic, and carnivore diets can produce temporary mental health benefits

10:36 – how impaired energy production underlies poor brain health and how to fix it without using low-carb diets

14:05 – how fat burning can temporarily relieve symptoms of poor glucose utilization (with a major cost)

18:29 – why fatty acid oxidation is our default metabolic state under stress and underlies all chronic disease

22:20 – whether ketogenic diets promote metabolic flexibility

24:53 – poor glucose metabolism as a driver of Alzheimer’s disease and other mental health conditions

28:13 – the adaptive benefit of burning fat during stress

31:31 – blood sugar management for Type 1 Diabetes and whether a low-carb diet is optimal

38:13 – whether lowering fat intake is necessary for burning and losing fat

42:09 – whether improving metabolic function alone is enough to reduce stored fat and when a decrease in dietary fat intake may be necessary

47:32 – the difference between subcutaneous fat and visceral fat and their potential implications

50:34 – how to fix our hunger signals to prevent excessive eating

54:33 – weighing the costs of extreme diets and the need for more innovative thinking around health

09 Nov 2020Ep. 33: Diet, Supplements, and Thyroid Health for Hypertension (Blood Pressure Part 3)00:47:16
In this episode we discuss:
  • ​How improving thyroid health will improve blood pressure regulation
  • The best supplements for managing blood pressure and vascular health
  • The role of vitamins A, D, E, and K in heart health and blood pressure regulation
  • How stress can cause elevated blood pressure
  • How to ensure that you have enough cellular energy to optimize vascular health and blood pressure
  Sign up for the free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy/   Click here to check out the show notes: https://jayfeldmanwellness.com/ep-33-diet-supplements-and-thyroid-health-for-hypertension-blood-pressure-part-3/
26 Sep 2024Ep. 123: Debunking the CICO Myth: Calorie Deficits Are NOT Required For Fat Loss01:33:39

In this episode we discuss:

  • Whether “calories in, calories out” is physiologically accurate
  • The many misconceptions related to “calories in, calories out”
  • Why a calorie deficit is NOT required for fat loss
  • Why “calories in, calories out” does not mean that eating less and exercising more is good advice for fat loss
  • What most people miss when it comes to “calories in, calories out”

 

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

 

Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/

 

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

 

 

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-123-debunking-the-cico-myth-calorie-deficits-are-not-required-for-fat-loss/

 

Timestamps:

0:00 – intro

1:07 – questions about the calories-in, calories-out (CICO) model of weight loss that I’ll be answering 

7:18 – what is (and isn’t) a calorie? 

11:49 – misapplications of CICO and why CICO is not physiologically accurate in the ways most people use it 

19:46 – why the idea that “a calorie is a calorie” is misleading 

29:11 – how energy in food is measured and the inaccuracy of food labels 

36:16 – the impact of behavioral compensation and metabolic adaptation on energy expenditure 

42:07 – how cutting calories lowers metabolism, reduces thyroid function, and increases stress hormones, appetite, and weight regain 

48:26 – Herman Pontzer’s Constrained Model of Energy Expenditure and the adverse effects of energy deficits 

52:21 – whether CICO can accurately represent physiology 

1:00:04 – a simplified version of CICO 

1:05:41 –why calories do not equal usable energy or weight 

1:13:27 – examples demonstrating the issues with common CICO misconceptions 

1:21:09 – summarizing the central issues with CICO and how you can lose body fat without a caloric deficit 

1:28:13 – whether there’s value to CICO

23 Nov 2020Ep. 34: Macros for Insulin Resistance & Diabetes and Melatonin & GABA for Sleep (Q & A)01:00:25
In this episode we discuss:
  • ​How to adjust macronutrient ratios for insulin resistance and diabetes
  • Factors that affect insulin sensitivity outside of macronutrient ratios
  • The problem with the vast majority of melatonin supplements
  • Whether GABA plays a role in sleep and how to support healthy GABA production
  • Why we may want to reconsider melatonin supplementation for better sleep and what we can do instead
  Sign up for the free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy/   Click here to check out the show notes: https://jayfeldmanwellness.com/ep-34-macros-for-insulin-resistance-diabetes-and-melatonin-gaba-for-sleep-q-a/
16 Oct 2024Ep. 124: Forget About CICO: A Smarter Approach to Fat Loss00:58:43

In this episode we discuss:

  • An alternative framework to CICO for conceptualizing fat loss
  • Why eating less and exercising more is not the best solution for fat loss
  • Why excess energy does not cause fat gain and instead leads to fat loss
  • How you can get stuck in a cycle of weight gain, undereating, and constant hunger, and how to get out of that cycle

 

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

 

Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/

 

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

 

 

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-124-forget-about-cico-a-smarter-approach-to-fat-loss/

 

Timestamps:

0:00 – intro

1:06 – recapping the problems with CICO

5:02 – the Energy Balance approach as an alternative to CICO for fat loss

12:12 – why calories do not equal energy and considering the possible fates of the food we consume

17:39 – efficient mitochondrial function as a central piece that determines whether substrate will be stored as body fat

19:39 – the amount of food you eat does matter

21:46 – conceptualizing Energy Balance with numerical units

24:00 – fat gain as a consequence of impaired mitochondrial function

29:01 – how you can lose fat while eating more

33:12 – the effects of energy availability on hunger and stress hormones

36:41 – how stress hormones, along with energy deficits, cause the body to break down muscle, bone, and skin for energy

43:16 – the benefits of having an energy surplus: improved sleep, immune function, digestion, cognitive function, and more

46:20 – comparing the Energy Balance approach with CICO and the major cost of the advice to “eat less and exercise more

11 Oct 2023Ep. 104: How Western Culture Keeps Us Distracted And Fighting Amongst Ourselves01:19:04
In this episode we discuss:
  • Individualism and competition vs. collaboration and communitarianism
  • Whether humans are inherently selfish and destructive 
  • The cost of social media and other forms of distraction
  • How drugs and alcohol can function as numbing agents 
  • Why many causes that appear worthy turn out to be distractions from the real problems

 

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

 

Download the Free Energy Balance Food Guide here: https://www.jayfeldmanwellness.com/guide/

 

Click here to check out the show notes: 

https://jayfeldmanwellness.com/ep-104-how-western-culture-keeps-us-distracted-and-fighting-amongst-ourselves/

 

Timestamps:

1:14 – individualism and competition vs. collaboration and communitarianism

25:45 – randomness, subjectivism, moral relativism, and the resulting nihilism

31:20 – the consequences of the idea that humans are selfish, destructive, and useless other than what we can produce

41:39 – how potentially beneficial advancements become co-opted to maintain the current power structure

48:04 – how western culture degrades esteem and prevents self-actualization

49:43 – the many aspects of modern technology and entertainment that distract us from what’s important

55:26 – how drugs and alcohol can also function as numbing agents

1:03:42 – how worthy causes become co-opted to prevent legitimate progress

1:13:18 – contrasting with cultures that are family-oriented and less distracted by technology

1:16:10 – the effects of culture in science, health, and everyday life   

14 Dec 2020Ep. 38: The Physiology of Fat Loss Without a Caloric Deficit01:13:55
In this episode we discuss:
  • The physiology of fat loss without a calorie deficit or cutting carbs or fat
  • Why insulin doesn’t cause fat gain
  • Where excess calories go if they aren’t stored as fat
  • Why increasing “fat-burning” doesn’t increase fat loss
  • Why it’s nearly impossible to accurately measure “calories in” and “calories out”
  • How an energy surplus can lead to healthy fat loss
  Sign up for the free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy/   Click here to check out the show notes: https://jayfeldmanwellness.com/ep-38-the-physiology-of-fat-loss-without-a-caloric-deficit/   Timestamps:   2:53  – the basics of fat loss without calorie, carb, or fat deficits 12:21 – the effects of hormones on fat gain and fat loss 21:12 – endotoxin and other factors that affect fat gain and fat loss 27:44 – a picture of fat loss without a calorie deficit 32:50 – is it even possible to accurately measure calories in and out? 36:56 – is the calorie in/calories out equation relevant to our physiology? 49:55 – the physiology of fat loss 53:36 – environmental factors as the culprit for weight gain 1:01:48 – how an energy surplus can support fat loss  
20 Aug 2021Ep. 68: Oxidative Stress, Choline Deficiency, and Exporting Liver Fat (NAFLD Part 6)01:06:37
In this episode we discuss:
  • How excess oxidative stress causes fat to accumulate in the liver

  • How a choline or methionine deficiency can contribute to fatty liver

  • Another mechanism by which PUFA cause fatty liver disease

  • How folate and vitamin B12 deficiencies can contribute to fatty liver

  • How PUFA decrease LDL and why this is NOT beneficial for general metabolic health or liver health

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-68-oxidative-stress-choline-deficiency-and-exporting-liver-fat-nafld-part-6/

 

Timestamps:

3:48 – how fat gets exported from our livers and why it matters in NAFLD

8:40 – how a choline, methionine, folate, or B12 deficiency can inhibit the liver’s ability to export fat

19:05 – how oxidative stress caused by PUFA and other factors inhibits the liver’s ability to export fat

27:50 – research showing that PUFA causes oxidative stress that inhibits the liver’s ability to export fat

42:11 – why lowering LDL by eating PUFA is NOT beneficial, both for general metabolic health and liver health

59:57 – other factors that drive oxidative stress and inhibit the liver’s ability to export fat

 

17 Jul 2021Ep. 65: How Fat-Burning And Low-Carb Diets Contribute to Fatty Liver (NAFLD Part 3)01:06:43
In this episode we discuss:
  • Why low-carb diets are NOT a good solution for fatty liver

  • How fat-burning and lipolysis actually contribute to fatty liver 

  • Why ketone production is a sign of stress and inhibited mitochondrial respiration

  • The role of uncoupling in NAFLD and why aiming to increase uncoupling is misguided 

  • Why low-fat diets don’t directly address the root cause of NAFLD

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-65-how-fat-burning-and-low-carb-diets-contribute-to-fatty-liver-nafld-part-3/

 

Timestamps:

3:56 – how fat-burning and lipolysis contribute to NAFLD

16:59 – the role of uncoupling in NAFLD

26:56 – how an energy failure and oxidative stress drive stress-processes in NAFLD

34:53 – the role of increases in stress hormones and fat-burning/lipolysis in NAFLD

37:54 – why low-carb diets drive stress and aren’t a good solution for fatty liver or insulin resistance

52:37 – the role of increases in stress hormones and fat-burning/lipolysis in NAFLD (cont.)

 

09 Aug 2021Ep. 67: Endotoxin and PUFA As Primary Causes of Fatty Liver Disease (NAFLD Part 5)01:47:45
In this episode we discuss:
  • How endotoxin drives inflammation and stress while downregulating our metabolism

  • Why alcoholic fatty liver disease isn’t all that different from non-alcoholic fatty liver disease

  • The protective effects of saturated fats in NAFLD

  • How endotoxin and polyunsaturated fats can cause NAFLD

  • Nutrient deficiencies that contribute to energy failure and NAFLD

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-67-endotoxin-and-pufa-as-primary-causes-of-fatty-liver-disease-nafld-part-5/ 

 

Timestamps:

3:57 – the role of endotoxin in NAFLD

23:43 – how endotoxin drives inflammation and stress while downregulating our metabolism

30:35 – research looking at endotoxin as the cause of NAFLD

38:30 – how endotoxin mediates alcoholic liver disease and the protective effects of saturated fats 

44:56 – endotoxin and other damaging factors in the larger context of NAFLD

52:52 – the role of PUFA in NAFLD

1:12:05 – the contrasting effects of saturated fats and PUFA in alcohol-induced liver damage

1:24:22 – how nutrient deficiencies can cause energy failure and drive NAFLD

1:34:57 – how alcohol causes fatty liver and why alcoholic liver disease doesn’t vary considerably from NAFLD

1:38:49 – other factors that contribute to energy failure and drive NAFLD, including psychological stress, fasting, low-carb diets, low-calorie diets, excessive exercise protective effects of saturated fats 

 

22 Jun 2020Ep 13: Lowering Cholesterol and The Role of Carbs in Ancestral Diets (Q & A)00:55:54
In this episode we discuss:
  • How you can lower blood cholesterol levels without medication (and why you may not want to)
  • Whether high cholesterol contributes to heart disease
  • Why the idea that carbohydrates weren’t available in ancestral diets is a fallacy
  • Whether we should shape our diets around ancestral or tribal diets
  • ​​The importance of carbohydrates for brain function and intelligence
   Sign up for the free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy/   Click here to check out the show notes: https://jayfeldmanwellness.com/ep-13-lowering-cholesterol-and-the-role-of-carbs-in-ancestral-diets-q-a/
12 Oct 2022Ep. 89: The Anti-Inflammatory Effects of Fruit Juice and The Hormonal Effects of PUFA vs. SFA01:05:22
In this episode we discuss:
  • Whether PUFA causes more oxidative stress than saturated fats

  • How PUFA intake affects testosterone

  • Whether fruit juice should be avoided for blood sugar regulation

  • The effects of fruit juice on inflammatory markers and endotoxin

  • Whether fruit juice has the same effects as soda

 

Check out the Energy Balance Solution group coaching program: https://jayfeldmanwellness.com/solution

 

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-89-the-anti-inflammatory-effects-of-fruit-juice-and-the-hormonal-effects-of-pufa-vs-sfa/ 

 

Timestamps:

4:10 – the effects of different dietary fat compositions on phospholipid and neutral lipid compositions in the testicles  

18:31 – the effects of different dietary fat composition on oxidative damage and antioxidant status in the testicles

29:44 – the effects of different dietary fat composition on hormone production and metabolism in the testicles 

38:26 – introducing the next study discussing the effects of orange juice on a high-fat, high-carbohydrate meal in terms of inflammation and endotoxin  

44:14 – the effects of orange juice on blood glucose and insulin sensitivity 

47:55 – the effects of orange juice on ROS production, TLR2 and TLR4 expression, and plasma endotoxin 

51:35 – factors that could account for the benefits of orange juice 

 

10 Jan 2025Ep. 127: Lipolysis and Fat Loss: Lose Body Fat Without Increasing Fat Burning00:54:30
In this episode we discuss:
  • Why increasing lipolysis through low-carb diets, cold plunges, fasting, and excess exercise is not necessary for fat loss
  • How less lipolysis can lead to more fat loss
  • The role of fat release and free fatty acids in diabetes, fatty liver disease, and obesity
  • What to focus on instead of lipolysis to support healthy fat loss

 

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

 

Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/

 

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

 

 

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-127-lipolysis-and-fat-loss-lose-body-fat-without-increasing-fat-burning/

 

Timestamps:

0:00 – intro

1:08 – the fat loss narrative: release more fat from your fat stores through intense exercise, fasting, cold plunges, and low-carb diets

4:08 – how fat gets released from our fat stores

8:40 – the baseline rate of fat release from our fat stores and the impact of degenerative states like cancer on lipolysis

12:09 – how fat is released from our fat stores in response to stressors like exercise

15:34 – the connection between lipolysis, metabolic syndrome, and fatty liver disease

23:29 – the research showing that decreasing lipolysis leads to less body fat (not more)

33:47 – whether we want to block hormone-sensitive lipase (HSL) activity

37:47 – the research showing that increasing fat burning and lipolysis does not increase fat loss

44:25 – how to lose body fat without relying on stress-driven fat oxidation

49:56 – strategies for fat loss without increased lipolysis: are exercise, fasting, and cold plunges the solution?

14 Apr 2020Ep. 3: Gut and Digestion Part 2: Ideal Foods For Our Gut00:47:43

In this episode we discuss:

  • How plant polyphenols shape our gut microbiome
  • ​Potential issues with fruits (and why fructose isn’t one of them
  • ​Why fats are essential for proper gut function and potential issues with low-fat diets
  • ​The importance of the migrating motor complex for a healthy gut and its relationship with our metabolic function
  • ​Why low-carb, keto, carnivore, and fasting (including intermittent fasting) aren’t ideal for our guts

Sign up for the free Energy Balance Mini Course here: https://jayfeldmanwellness.com/energy/

    Click here to check out the show notes: https://jayfeldmanwellness.com/ep-3-gut-and-digestion-part-2-ideal-foods-for-our-gut/ 
23 Jun 2022Ep. 84: Fructose and Uric Acid: Are David Perlmutter and Rick Johnson Wrong? (Part 1)01:32:22
In this episode we discuss:
  • Whether David Perlmutter and Rick Johnson are right about fructose and uric acid being drivers of poor metabolic health

  • Why fructose will not cause ATP depletion when it’s consumed in normal contexts

  • Why fructose and uric acid are not the drivers of metabolic syndrome and degenerative conditions

  • The protective effects of fructose in the liver

  • Why it’s extremely important to consider the different contexts in which uric acid is produced

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-84-fructose-and-uric-acid-are-david-perlmutter-and-rick-johnson-wrong-part-1/ 

 

Timestamps:

3:56 – why we’re discussing fructose and uric acid

8:38 – the general argument that fructose consumption drives uric acid production and that this is responsible for disease and degeneration

14:48 – our general counterargument that fructose consumption does not drive disease and degeneration via uric acid production

18:41 – whether fructose depletes ATP in the liver 

30:03 – fructose is extremely protective and generally increases ATP availability in the liver 

36:27 – how fructose can increase uric acid via ATP depletion

38:51 – why fructose doesn’t cause ATP depletion and uric acid production unless it’s given in extreme, non-physiologically relevant contexts

1:04:50 – whether uric acid is the driver of metabolic syndrome and many degenerative conditions by driving oxidative stress 

1:15:46 – why xanthine oxidase is a major confounding variable to consider when evaluating whether uric acid production is harmful

1:27:02 – whether the activation of AMP deaminase is a reason not to consume fructose

1:27:55 – average fructose intakes are far below the amounts that are typically used in research

 

08 Nov 2021Ep.74: Refuting Nutrition With Judy’s “Thoughts on the Ray Peat Diet” (Part 2)01:33:00
In this episode we discuss:
  • Why low-carb diets are inherently stressful

  • How carbohydrates oppose stress and decrease the stress hormones

  • Why carbohydrates ARE essential and why their intake plays a vital role in our endocrine systems  

  • Whether most people have hypothyroidism and how carnivore diets can cause hypothyroidism

  • Why carnivore diets are NOT ideal for gut health even if they improve symptoms in the short-term 

  • The real reason why people are moving from a carnivore diet to a “Ray Peat Diet”

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-74-refuting-nutrition-with-judys-thoughts-on-the-ray-peat-diet-part-2/ 

 

Timestamps:

3:03 – why low-carb diets drive physiological stress and carbohydrates oppose stress

21:51 – why carbohydrates are essential and why our endocrine systems are so tightly tuned to carbohydrate intake

29:19 – do most people have hypothyroidism?

44:38 – is hypothyroidism ever the root problem?

53:28 – how carnivore diets can cause hypothyroidism

1:01:36 – whether taking exogenous steroid hormones (like pregnenolone or progesterone) will increase cortisol

1:12:19 – should we focus on gut health over thyroid health?

1:23:31 – why are people really moving from carnivore to a “Ray Peat Diet?”

25 May 2020Ep. 9: Polyunsaturated Fats (PUFA) and Energy Balance00:57:17

In this episode we discuss:

  • ​​​The differences between saturated and unsaturated fats
  • ​Which fats encourage hibernation and slow our metabolism
  • ​Why ​removing one type of fats is one of the best things you can do to increase your cellular energy
  • ​Why polyunsaturated fats (PUFA) aren’t the “heart-healthy” fats we’re told they are
  • ​Which fats we should be eating to maximize our cellular energy
  Sign up for the free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy/   Click here to check out the show notes: https://jayfeldmanwellness.com/ep-9-polyunsaturated-fats-pufa-and-energy-balance/
14 Sep 2020Ep. 25: How to Slow Aging Part 3: Diet, Exercise, and Stress for Longevity and Anti-Aging00:47:08

In this episode we discuss:

  • The best types and amount of exercise to slow aging and increase lifespan
  • Why small amounts of stress (via hormesis) don’t contribute to longevity and slowed aging
  • How to balance amino acids and protein intake to slow aging and extend lifespan (without protein fasting)
  • The impact of stress hormones on longevity and aging and how to optimize gut health, carb intake, and calorie intake to minimize stress hormones
  • One of the most important factors when it comes to aging and lifespan that has nothing to do with nutrition and exercise

 

Sign up for the free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy/

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-25-how-to-slow-aging-part-3-diet-exercise-and-stress-for-longevity-and-anti-aging/

08 Jun 2020Ep. 11: Weight Loss Part 2: The True Cause of Weight Gain00:42:38
In this episode we discuss:
  • Why we don’t want to cut carbs, fat, or calories to lose weight
  • ​Why fat gain and low energy go hand-in-hand
  • Why “hyperpalatability” is not the cause of overeating (and what is)
  • ​Our personal experiences with “eating less and exercise more”
  • ​Why carbs and insulin are not responsible for weight gain
  • ​What causes dysregulated hunger signals, leaving you feeling full but starving
  Sign up for the free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy/   Click here to check out the show notes: https://jayfeldmanwellness.com/ep-11-weight-loss-part-2-the-true-cause-of-weight-gain/
19 Sep 2024BV #1: Bryan Johnson’s Longevity Diet, How Stress Affects Our Cells, & Whether Glucagon is Evil02:03:49

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

 

The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/

 

Danny's Telegram: https://t.me/dannyroddy

 

Timestamps:

0:00 – intro

0:33 – why we started this podcast

6:25 – our take on Bryan Johnson’s Longevity Blueprint and problems with biohacking

12:13 – whether we should adopt any of the strategies from Bryan Johnson’s Blueprint to achieve optimal health

14:50 – the cost of continually being in a caloric deficit and why this does not increase longevity

21:06 – issues with eating hard-to-digest foods and whether supplements can make up for missing nutrients in the diet

22:13 – the importance of avoiding reductionistic thinking around supplements touted for weight loss benefits

28:00 – potential pros and cons of Bryan Johnson’s Blueprint and how to measure health

32:39 – Bryan Johnson’s supplement protocol

41:09 – how low-carb diets negatively affect NAD+ to NADH ratios and estrogen status

46:20 – whether body fat percentage and cholesterol levels can be too low

52:20 – what is stress?

1:03:20 – issues with hormesis and the idea that stress is beneficial

1:07:34 – whether avoiding stress is possible and how to develop resilience to stress

1:13:17 – addressing Marty Kendall’s response to our take on glucagon and insulin

1:24:17 – glucagon’s short-term and long-term effects on metabolic function

1:26:46 – glucagon’s role in insulin resistance and type 2 diabetes

1:37:16 – metabolic dysfunction as a driver of insulin resistance

1:41:06 – whether we need to be concerned about wasting energy on hormone production

1:44:50 – whether we should always try to avoid gluconeogenesis

1:51:45 – how to use carbohydrates to stabilize your blood sugar

1:56:11 – habit stacking, simplifying supplementation, and adopting a long-term mindset when it comes to health

07 Nov 2022Ep. 90: Eating 5,000 Calories Per Day, Fish Oil, Water Weight vs. Body Fat, Paleo-Ketogenic Diet (Q & A)01:24:19
In this episode we discuss:
  • Whether fish oil is beneficial due to its anti-inflammatory and cholesterol-lowering effects

  • Our thoughts on the benefits from a paleo-ketogenic diet

  • What to do if you’re dealing with dental issues from sugar consumption

  • Our experiences eating 5,000 to 6,000 calories per day

  • The best time to eat the carrot salad

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-90-eating-5000-calories-per-day-fish-oil-water-weight-vs-body-fat-paleo-ketogenic-diet-q-a/ 

 

Timestamps:

2:44 – why fish oil shows anti-inflammatory and cholesterol-lowering effects, and why this doesn’t mean they’re beneficial 

11:25 – eating carrots with a meal versus away from a meal 

17:27 – our thoughts on the benefits from a paleo-ketogenic diet 

28:45 – which coral calcium supplement we recommend 

32:33 – dental issues from sugar consumption 

39:45 – what we think of orange juice with added calcium 

41:36 – how to determine whether weight gain is due to water weight or body fat  

51:57 – our experiences eating 5,000-6,000 calories per day 

1:03:23 – whether it’s helpful to use calorie calculators and context to consider when it comes to calorie calculators 

1:11:20 – how our current diets vary in contrast to when we were eating 5,000-6,000 calories per day

 

28 Mar 2024Ep. 111: Stevia vs. Sugar, Ketogenic Diets for Epilepsy, and Spore-Based vs Standard Probiotics (Q & A)01:02:33
In this episode we discuss:
  • How spore-based probiotics differ from typical probiotics and whether we should be using either of them to improve our gut health 
  • Whether low-carb or ketogenic diets are an ideal solution for epilepsy 
  • The role of gut health and metabolism in epileptic seizures
  • Concerns with using low- or no-calorie sweeteners
  • Whether stevia is actually any better than artificial sweeteners

 

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

 

Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/

 

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

 

The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/

 

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-111-stevia-vs-sugar-ketogenic-diets-for-epilepsy-and-spore-based-vs-standard-probiotics-qa

 

Timestamps:

0:00 – intro

1:17 – whether spore-based probiotics can cause bacterial overgrowths like SIBO

4:53 – the drawbacks of standard probiotic use and the limitations of stool testing

9:55 – how spore-based probiotics protect against pathogenic bacteria and endotoxin and which spore-based product Jay recommends

15:39 – long-term benefits of spore-based probiotics and how long you need to use them for these benefits

21:05 – whether low-carb or ketogenic diets are necessary to improve epilepsy 

29:25 – using ketones for fuel and why the production of ketones isn't the problem on a ketogenic diet 

30:48 – the main drivers of epileptic seizures and how ketones help to prevent or reverse them 

34:17 – the role of the gut microbiome in brain health and epilepsy

42:18 – concerns with low- or no-calorie sweeteners like stevia

48:03 – whether we should be concerned about the lack of nutrients in table sugar, honey, and maple syrup 

54:55 – stevia as a potential endocrine disruptor that may have negative effects on the thyroid, liver, and kidneys 

01 Feb 2021Ep. 45: Supplements for Autoimmune Conditions and Immune Health (Autoimmunity Part 4)00:53:31
In this episode we discuss:
  • The best supplements to help protect against and reverse autoimmune conditions

  • Why fighting against ourselves (and our immune systems) is NOT the answer for autoimmune conditions

  • How to use supplements in the context of a systemic, bioenergetic approach to autoimmune conditions

  • The problems with the term “autoimmune disease”

  • Effective supplements that support our metabolism and immune system

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-45-supplements-for-autoimmune-conditions-and-immune-health-autoimmunity-part-4/

 

Timestamps:

4:53 – B vitamins for autoimmune conditions

11:09 – antibiotics for autoimmune conditions

16:26– pro-metabolic and anti-inflammatory supplements for autoimmune conditions

23:02 – fat soluble vitamins (vitamins A, D, E, K) for autoimmune conditions

29:45 – taurine and glycine for autoimmune conditions

33:25 – other pharmaceuticals for autoimmune conditions

36:01 – why supplements aren’t the solution, but are rather one part of a systemic approach

42:42 – why we don’t want to fight against ourselves (and our immune systems) if we have an autoimmune condition

 
04 Jan 2021Ep. 41: Benefits of Progesterone and How to Restore Hormonal Health (Women’s Hormonal Health Part 2)01:04:19
In this episode we discuss:
  • Why estrogen dominance is one of the primary drivers of reproductive issues for women

  • The cost of suppressing hormonal and reproductive symptoms with birth control

  • Whether symptoms like breast soreness, bloating, cramps, heaviness, mood swings, migraines, PCOS, fibroids, and endometriosis can be resolved by correcting underlying dysfunction

  • Why estrogen is not the “female hormone” and is instead better classified as a stress hormone

  • The healthiest form of birth control/contraception

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-41-benefits-of-progesterone-and-how-to-restore-hormonal-health-womens-hormonal-health-part-2/

 

Timestamps:

4:10 – the harmful effects of various forms of contraception and using menstrual cycles as indicators of health status

13:44 – the beneficial effects of progesterone and its roles outside of reproduction

16:54 – context for hormone supplementation (including estrogen or progesterone supplementation and hormone replacement therapy)

28:25 – the problems with hormone blood tests and how this has led to misconceptions surrounding the effects of estrogen on our health

33:16  – nutrition to rebalance hormones without hormonal supplementation

55:44  – supplements (vitamin A, vitamin D, vitamin E, vitamin K, aspirin, progesterone, thyroid) to improve hormonal health

 
16 Aug 2024Ep. 121: How To Address Adrenal Fatigue, GAPS Diet Concerns, and Gallbladder Health (Q&A)01:26:28

In this episode we discuss:

  • How to fix adrenal fatigue and adrenal insufficiency and whether these are really adrenal problems
  • Whether it makes sense to use desiccated adrenal products or hydrocortisone for adrenal fatigue
  • How the GAPS diet can resolve autoimmune issues and whether you should consider trying it
  • How to improve fat digestion and bile flow
  • How to improve digestion without a gallbladder

 

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

 

Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/

 

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

 

The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/

 

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-121-how-to-address-adrenal-fatigue-gaps-diet-concerns-and-gallbladder-health/

 

Timestamps:

0:00 – intro

1:13 – what is adrenal insufficiency and what causes it?

7:02 – what is adrenal fatigue and how can we reverse it?

11:54 – the drivers of adrenal fatigue and issues with typical treatments

18:51 – the importance of establishing solid diet and lifestyle foundations before adding supplements for adrenal support

24:42 – whether our bodies lose the ability to produce hormones as we age

27:20 – concerns with the use of natural supplements like desiccated adrenal glandulars, licorice, and hormone replacement therapy (HRT)

36:07 – whether the GAPS diet is ideal for healing autoimmune conditions

40:01 – problems with the GAPS diet and other elimination diets

47:37 – the importance of individualizing your gut protocol and the problems with a cookie-cutter approach

52:09 – the connection between gut health, stress hormones, mental health, and autoimmunity

55:40 – how to improve digestion without a gallbladder

59:13 – common issues seen in those without a gallbladder

1:02:08 – long-term consequences of gallbladder removal and how to heal gallbladder issues

1:05:30 – when to use ox bile, TUDCA, taurine, glycine, or vitamin C

1:09:16 – how much fat to include in your diet to stimulate bile flow, and what types of fats are optimal

1:12:55 – strategies for preventing and resolving bile dumping and reflux

1:15:44 – additional consequences of gallbladder removal

1:17:36 – gallbladder issues in relation to hypothyroidism and estrogen dominance

13 Dec 2021Ep. 77: Why You DON’T Want to Force Autophagy, Mitochondrial Biogenesis, & Uncoupling (Hormesis Part 3)01:13:24
In this episode we discuss:
  • Why the stress caused by calorie restriction, exercise, cold thermogenesis, fasting, ketogenic diets, Wim Hoff breathing, and supplements like resveratrol is not supportive of our health

  • Why autophagy, mitochondrial biogenesis, and uncoupling are not always beneficial

  • Whether being tolerant to stress is a sign of health

  • Why it’s virtually impossible to apply hormesis in a practical sense

  • The difference between reactive oxygen species production in a high energy state versus a low energy state

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-77-why-you-dont-want-to-force-autophagy-mitochondrial-biogenesis-uncoupling-hormesis-part-3/ 

 

Timestamps:

3:27 – why reductions in adaptive responses in degenerative states and the benefits of “hormetic” interventions does not lend support to hormesis

13:49 – why improving tolerance to stress is not inherently beneficial and the cost of stress across generations

28:58 – how the fact that stress is cumulative throws a wrench in the idea of hormesis  

37:05 –the difference between producing ROS in a high energy state versus a low energy state

49:16 – the low energy, high ROS state is a feature of degenerative conditions

 

23 Nov 2020Ep. 35: Putting An End to Dieting, Binging, and Restriction (The Holiday Anti-Diet Part 1)00:57:39
In this episode we discuss:
  • ​How to get through the holidays without binges and weight gain without resorting to restriction
  • Why eating more, not less, is often the answer for healthy fat loss
  • How to prevent binging by ensuring you have enough cellular energy
  • Why weight gain and a lack of energy often go hand-in-hand
  • How to stop cravings and hunger without restriction and dieting
  Sign up for the free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy/   Click here to check out the show notes: https://jayfeldmanwellness.com/ep-35-putting-an-end-to-dieting-binging-and-restriction-the-holiday-anti-diet-part-1/
07 Dec 2020Ep. 37: Maximizing the Benefits of Coffee and Whether Fasting Protects Against Cancer (Q & A)01:00:52
In this episode we discuss:
  • ​The pro-metabolic effects of coffee that lead to cancer prevention, improved liver health, neurological protection, increased insulin sensitivity, and reduced all-cause mortality
  • How to drink coffee so that it improves your health instead of causing stress
  • Whether it’s okay to drink coffee every day or even drink multiple cups per day
  • How we can attain the benefits of fasting without the stress and without starving ourselves
  • Whether fasting is actually protective against cancer and longevity-promoting
  • Why fasting decreases muscle mass and drives hormonal imbalances
  Sign up for the free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy/   Click here to check out the show notes: https://jayfeldmanwellness.com/ep-37-maximizing-the-benefits-of-coffee-and-whether-fasting-protects-against-cancer-q-a/   Timestamps: 3:27 – the benefits of coffee, the best way to drink it, and how to tell if it’s helping or harming your health 15:43 – how much coffee is ideal and whether it’s okay to have coffee every day 21:32 – when to use supplements to protect against a suboptimal environment and the importance of context 31:20 – whether fasting can have benefits 36:20 – whether fasting protects against and/or destroys cancer 45:21 – the harmful effects of fasting and alternative strategies to achieve the same benefits  
28 Sep 2020Ep. 27: What We Eat in a Day, Diet Freedom and Variety, and the NAD+/NADH Ratio (Q & A)00:56:07
In this episode we discuss:
  • ​What Mike and I typically eat in a day
  • How to individualize your diet to your needs and various snack and meal ideas you can try
  • The problem with excessive diet rigidity and the idea of “cheating” on your diet
  • The importance of the NAD+/NADH ratio in metabolism, health, and aging
  • The consequences of the normalization of unhealthy diets and lifestyles
  Sign up for the free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy/   Click here to check out the show notes: https://jayfeldmanwellness.com/ep-27-what-we-eat-in-a-day-diet-freedom-and-variety-and-the-nad-nadh-ratio-q-a/
01 Mar 2021Ep. 49: Calorie Deficiencies, Carbohydrate Deficiencies, and Protein Excess (Men’s Hormonal Health Part 1)00:54:34
In this episode we discuss:
  • How to improve male reproductive health from the bioenergetic view

  • Why low-carb diets, intermittent fasting, and fasted cardio are inherently harmful to hormonal health

  • Why eating enough food is paramount for increasing libido, gaining muscle, and improving hormonal health

  • The problem with treating lab values rather than treating the person

  • How carbohydrate deficiencies can decrease androgens and drive hormonal imbalances

  • How eating too much protein can decrease your metabolism and harm hormonal health and the ideal amount of protein for hormonal health

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-49-calorie-deficiencies-carbohydrate-deficiencies-and-protein-excess-mens-hormonal-health-part-1/

 

Timestamps:

3:12 – androgens and men’s reproductive health in the bioenergetic context

16:36 – why eating enough food is paramount for increasing libido, gaining muscle, and improving hormonal health, and where to start when determining how much to eat

31:20 – why carbohydrates are vital for increasing androgens, building muscle, and supporting men’s reproductive health

43:49 – the problems with over-eating protein and the ideal protein intake for body composition and hormonal health

 

03 Oct 2022Ep. 88: Whether Soy Is Estrogenic And Causes Infertility00:50:33
In this episode we discuss:
  • The hormonal effects of compounds in soy

  • How the effects of BPA compare to soy 

  • Whether soy is estrogenic and causes infertility

  • Whether the amount of soy typically consumed is sufficient to create these effects

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-88-whether-soy-is-estrogenic-and-causes-infertility/ 

 

Timestamps:

3:06 – overview of the study we’ll be discussing 

5:57 – compounds in soy have potentially estrogenic thymic, immune, and hormonal effects 

10:20 – compounds in soy oppose testosterone and reduce its production 

13:33 – whether animal research translates to humans 

16:40 – BPA has anti-fertility effects in males that are parallel to supplemental estrogen 

27:39 – corn oil causes weight gain despite the same number of calories consumed

32:11 – the reproductive effects of soy, BPA, and estradiol 

44:50 – the amount of soy required to cause these reproductive effects 

 

25 Jan 2024Ep. 108: Herman Pontzer’s Burn, Ted Naiman’s PE Diet, and Increasing Calorie Intake to Raise Metabolism (Q & A)01:10:18
In this episode we discuss:
  • The unexpected costs of using excess exercise to lose weight 
  • Our thoughts on Herman Pontzer’s book Burn and the Constrained Model of Energy Expenditure 
  • Our thoughts on Ted Naiman’s protein to energy ratio diet (PE Diet) 
  • The cost of eating too much protein and what to do instead 
  • How to increase caloric intake to raise your metabolism and reverse hypothyroidism 
  • The major category of nutrients that’s often missed for optimizing mitochondrial function 

 

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

 

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

 

 

Click here to check out the show notes: https:/jayfeldmanwellness.com/ep-108-herman-pontzers-burn-ted-naimans-pe-diet-and-increasing-calorie-intake-to-raise-metabolism-qa/

 

Timestamps:

1:25 – Herman Pontzer’s Constrained Model of Energy Expenditure and the adverse effects of energy deficits

7:13 – problems with the additive model of energy expenditure and the physiological cost of excess exercise

10:40 – environmental factors that we can change to increase metabolism

16:42 – the unexpected costs of using excessive exercise to lose weight

19:16 – weight gain as an adaptive response to an energy deficit

22:46 – when eating too much can be a problem and how to identify your ideal calorie intake

32:18 – Ted Naiman’s protein to energy ratio diet and optimal protein intake

41:13 – the problems with using protein as an energy source

46:45 – how to increase caloric intake to raise metabolism and reverse hypothyroidism

50:47 – how to track your symptoms and progress to better guide your nutrient goals

56:55 – the best foods for increasing calorie intake and what to do if you have a low appetite

1:00:30 – the essential role of both macro and micronutrient density in promoting mitochondrial health

1:04:00 – why sugar cravings are not the same as sugar addiction

1:06:46 – easy ways to incorporate more macro and micro nutrient dense foods into your diet

01 Aug 2023Ep. 97: How To Properly Test For Thyroid Function (Hypothyroidism Part 3)01:24:47
In this episode we discuss:
  • What causes Hashimoto’s hypothyroidism 
  • How to properly interpret your thyroid bloodwork (and what your doctor likely doesn’t know about thyroid testing)
  • How your cholesterol values can be used as markers of thyroid status 
  • How symptoms like metabolic rate, body temperature, and pulse rate can be more helpful than blood tests when identifying thyroid status 
  • Ideal blood test values for optimal thyroid function 

 

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-97-how-to-properly-test-for-thyroid-function-hypothyroidism-part-3

 

Timestamps:

0:00 – intro 

1:17 – what causes Hashimoto’s hypothyroidism and autoimmunity in general

13:30 – how to interpret thyroid blood tests (TSH, T3, T4, rT3) 

31:34 – what reverse T3 means on a blood test and how to interpret rT3 values

34:44 – looking at all thyroid markers together to determine thyroid status 

37:05 – the anti-thyroid effects of reverse T3

40:38 – cholesterol levels as a marker of thyroid status, and the problems with cholesterol levels that are too high or too low

52:34 – the relationship between cholesterol, heart disease, and thyroid status

56:04 – other blood markers that can be indicative of thyroid status (SHBG, ferritin)

57:02 – how we can use symptoms like metabolic rate, body temperature, and pulse rate to determine thyroid status  

1:12:14 – other symptoms that can be used as indicators of thyroid status (low energy, fatigue, low immune function, dry or cracking skin, hair loss brittle nails, slow motility, weight gain, low mood)

24 Aug 2020Ep 22: Resolving Joint Pain and Whether Reducing Stress Hormones Works For Fat Loss (Q & A)00:55:49
In this episode we discuss:
  • Why the general notion that gaining body fat increases the risk of disease isn’t always the case
  • Whether whole foods are always healthier than processed foods (you might be surprised by this one)
  • Whether sugar and salt can support fat loss
  • Possible causes of chronic pain and how to resolve them
  • Why many common recommendations for joint pain can cause more harm than good (and what to do instead)
  Sign up for the free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy/   Click here to check out the show notes: https://jayfeldmanwellness.com/ep-22-resolving-joint-pain-and-whether-reducing-stress-hormones-works-for-fat-loss-q-a/
11 Jan 2021Ep. 42: Alternative Views of The Immune System and Autoimmunity (Autoimmunity Part 1)00:53:39
In this episode we discuss:
  • Why elimination diets and avoiding dietary triggers is not the solution for autoimmunity

  • The role of the gut health and intestinal permeability in autoimmune conditions (and why “leaky gut” isn’t the primary cause of autoimmunity)

  • The problems with immunosuppression and symptom management for autoimmune conditions

  • Alternative views of the immune system that create a completely different picture of autoimmunity

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-42-alternative-views-of-the-immune-system-and-autoimmunity-autoimmunity-part-1/

 

Timestamps:

3:45 – the autoimmunity epidemic

6:54 – the basics of our immune system

12:55 – the mainstream view of autoimmunity

17:20 – the functional medicine/paleo view of autoimmunity involving molecular mimicry and intestinal permeability (leaky gut)

31:12 – the problems with the functional medicine/paleo view of autoimmunity

41:45 – the problems with the conventional view of the immune system

48:06 – an alternative view of the immune system (William Koch’s theory natural immunity, Polly Matzinger’s danger theory, Jamie Cunliffe’s morphostasis theory)

 
10 Aug 2023Ep. 98: How To Optimize Your Diet & Lifestyle For Hypothyroidism (Hypothyroidism Part 4)00:51:56
In this episode we discuss:
  • How fasting decreases thyroid function  
  • Why carbs are essential for thyroid function 
  • Specific anti-thyroid foods to avoid  
  • Why interventions like cold thermogenesis, caloric restriction, and fasting are not the answer for hypothyroidism 
  • The impact of sleep on our thyroid health 

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

 

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-98-how-to-optimize-your-diet-lifestyle-for-hypothyroidism-hypothyroidism-part-4

 

Timestamps:

0:00 – intro 

1:06 – how to address and reverse hypothyroidism

2:36 – the importance of carbs, calories, and fat for improving thyroid function

16:24 – the importance of eating consistently (and not fasting) for thyroid function

18:00 – saturated fats vs. PUFA and micronutrients for thyroid function

19:45 – basic bioenergetic diet recommendations for hypothyroidism

22:14 – anti-thyroid foods (goitrogens) to avoid

23:08 – other diet considerations when transitioning to a bioenergetic approach

25:56 – low iron in women and excess iron from carnivore or keto diets

27:47 – cruciferous vegetables and thyroid health

28:43 – how to properly address nutrient deficiencies for thyroid health

35:06 – whether stressors like exercise, cold thermogenesis, caloric restriction, and fasting are supportive of thyroid health

47:54 – optimizing sleep for thyroid function

07 Jul 2021Ep. 64: The True Cause of Fatty Liver (NAFLD Part 2)01:01:12
In this episode we discuss:
  • Why fructose doesn’t cause leptin resistance

  • How our livers produce fat from fructose or dietary fat

  • How a failure of energy production (mitochondrial respiration) causes NAFLD 

  • Why increases in uncoupling, autophagy, mitophagy, and other stress pathways is often a sign of dysfunction and stress

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-64-the-true-cause-of-fatty-liver-nafld-part-2/ 

 

Timestamps:

4:54 – why fructose doesn’t cause leptin resistance 

11:56 – the physiology of triglyceride (fat) synthesis in the liver

28:03 – the role of inhibited, inefficient mitochondrial respiration in triglyceride synthesis in the liver

46:06 – the role of inhibited, inefficient mitochondrial respiration and stress pathways in NAFLD

 

06 Sep 2023Ep. 101: Building a Bioenergetic Diet: Optimal Carb, Fat, and Protein Sources00:40:50
In this episode we discuss:
  • Why you want to avoid vegetarian-fed chicken and acorn-fed pork 
  • The best bioenergetic fat, protein, and carb sources 
  • Why it’s best to avoid salmon and bluefin tuna, and what fish and seafood to have instead 
  • Whether we should be including vegetables and fiber in our diet 
  • How to avoid vegetable oils and what fats to use instead 
  • When it makes sense to include high-FODMAP foods 

 

Download the Free Energy Balance Food Guide here: https://www.jayfeldmanwellness.com/guide/

 

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-101-building-a-bioenergetic-diet-optimal-carb-fat-and-protein-sources/

 

Timestamps:

0:00 – intro 

1:34 - bioenergetic food guide 

2:59 - bioenergetic fat sources 

6:20 - bioenergetic protein sources 

15:01 - the importance of collagen/gelatin 

18:51 - bioenergetic carbohydrate sources 

31:25 – foods and additives to avoid 

34:15 – experimentation and context as primary components of the bioenergetic view 

 

30 Nov 2020Ep. 36: Fixing Our Dysfunctional Relationship with Food (The Holiday Anti-Diet Part 2)01:03:42
In this episode we discuss:
  • ​The process of removing judgement and morality from health and nutrition
  • Why ice cream can be considered a health food
  • Why losing weight through the mainstream model often comes at the cost of our health
  • How the diet and nutrition industries have caused us to develop a dysfunctional relationship with food
  • How to transition away from the “eat less and exercise more” paradigm of fat loss
  Sign up for the free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy/   Click here to check out the show notes: https://jayfeldmanwellness.com/ep-36-fixing-our-dysfunctional-relationship-with-food-the-holiday-anti-diet-part-2/
06 Jul 2020Ep. 15: The Failures of Modern Medicine Part 1: Industry Influence and Historical Mishaps00:54:00
In this episode we discuss:
  • Why conventional medicine is effective for treating acute illness and injury but not chronic health conditions or illness prevention
  • How the business side of healthcare often takes precedence over our health
  • What’s missing in medical education
  • Why we can’t always trust the research and need to consider it with a critical eye
  • Recent instances where damaging and dangerous treatments have been supported by conventional medicine
   Sign up for the free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy/   Click here to check out the show notes: https://jayfeldmanwellness.com/ep-15-the-failures-of-modern-medicine-part-1-industry-influence-and-historical-mishaps/
22 Nov 2022Ep. 91: Cod Liver Oil Dangers, The Croissant Diet, and Insulin-Resistant Fat Cells (Q & A)00:57:48
In this episode we discuss:
  • Whether cod liver oil is an ideal source of vitamin A/retinol

  • Whether we should be concerned about the omega-3 content of cod liver oil (CLO)

  • The idea that we want our fat cells to be insulin resistant to lose fat

  • Whether keeping insulin low is the key to fat loss

  • What hormones regulate fat loss

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-91-cod-liver-oil-dangers-the-croissant-diet-and-insulin-resistant-fat-cells-q-a/ 

 

Timestamps:

2:54 – what we think about cod liver oil as a vitamin A source  

9:50 – why someone may benefit from cod liver oil, and why it likely isn’t a result of the retinol  

10:56 – the immunosuppressive effects of omega-3s 

14:25 – the major problems with omega-3s, including cod liver oil specifically 

25:33 – clarifying our thoughts on the Croissant Diet 

28:26 – burning saturated fat versus burning PUFA and whether PUFA create more ROS than saturated fats  

31:41 – what we think of the idea that consuming saturated fats will allow for fat loss by causing insulin resistance in the adipocytes (fat cells)  

42:50 – why increasing fat burning doesn’t inherently lead to increased fat loss 

47:11 – whether increasing satiety is the key to fat loss 

 

15 Feb 2021Ep. 47: A Critique of The ROS Theory of Obesity (The Croissant Diet Part 1)01:12:03
In this episode we discuss:
  • The major issues with the ROS theory of obesity

  • Why fat-burning is inefficient and doesn’t lead to healthy fat loss

  • The real problem with PUFA (and why they don’t decrease ROS production)

  • Why carbohydrates and insulin don’t cause fat gain

  • How increasing cellular energy through efficient mitochondrial respiration is the key to healthy fat loss

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-47-a-critique-of-the-ros-theory-of-obesity-the-croissant-diet-part-1/

 

Timestamps:

3:26 – an introduction to The Croissant Diet and Fire In A Bottle

10:04 – an introduction to ROS and the varying ROS-producing effects of fats and carbs

16:10 – the ROS theory of obesity, Randle cycle confusion, and how fat-burning causes physiological insulin resistance

25:30 – the effect of fatty acid saturation on ROS production when oxidized in mitochondria

29:36 – the real problem with PUFA and why they lead to increases in ROS production rather than decreases

42:28 – why the inefficient mitochondrial respiration that’s fueled by fatty acid oxidation and produces excessive amounts of ROS harms our health

47:39 – the problems with the idea of hormesis

58:39 – why fat-burning doesn’t increase fat loss

1:05:45 – anti-hormesis and the bioenergetic view of obesity

 
09 Apr 2024Ep. 112: The Problems with Resistant Starch and Balancing the Calcium to Phosphorus Ratio (Q&A)00:39:53
In this episode we discuss:
  • Why you might want to think twice about using resistant starch for blood sugar regulation and gut health
  • Ways to increase or reduce the amount of resistant starch in the foods you eat 
  • How to tell if resistant starch is negatively impacting your gut health, and why non-resistant starch may also pose a problem
  • The optimal calcium to phosphorus ratio according to the research
  • The calcium paradox and why calcium intake doesn’t increase excitation or calcification
  • The hidden dangers of excess phosphorus intake 

 

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

 

Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/

 

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

 

The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/

 

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-112-the-problems-with-resistant-starch-and-balancing-the-calcium-to-phosphorus-ratio-qa

 

Timestamps:

0:00 – intro

1:00 – mainstream health claims about resistant starch and why we disagree

6:15 – whether there are any benefits to including resistant starch in your diet

11:07 – how to tell if resistant starch is negatively impacting your gut health and how to avoid it

16:05 – which starches are easiest to digest and the factors that affect our ability to digest starches optimally

21:38 – why we should pay attention to our calcium to phosphorus ratio and the risks of high parathyroid hormone levels

26:19 – the optimal calcium to phosphorus ratio and the calcium paradox in terms of regulating blood pressure 

31:21 – which phosphorus-containing foods we should avoid to optimize bone density 

34:36 – the calcium paradox and why consuming calcium doesn’t increase intracellular calcium

13 Jul 2020Ep. 16: The Failures of Modern Medicine Part 2: Dangerous Treatments and Medical Error00:48:34
In this episode we discuss:
  • How dogmatism interferes with science and medicine
  • Current treatments and medications that are dangerous and ineffective (including some of the most commonly prescribed drugs and surgeries)
  • ​How an overemphasis on labs and screenings has led to harmful over- and under-treatment
  • ​The fact that medical error is one of the leading causes of death
  • ​How we can best advocate for ourselves and ensure proper healthcare
  Sign up for the free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy/   Click here to check out the show notes: https://jayfeldmanwellness.com/ep-16-the-failures-of-modern-medicine-part-2-dangerous-treatments-and-medical-error/
27 Sep 2023Ep. 103: How Western Culture Keeps Us Poor And Destroys Our Family, Community, and Relationships01:03:15
In this episode we discuss:
  • How lower wages and higher costs have dramatically reduced our quality of life
  • How we’ve ended up working more and resting less with worse outcomes
  • Whether advancements in technology have improved the quality of life of the average person
  • How marketing and consumerism keep us on the hamster wheel
  • The hidden costs of convenience culture
  • Concerns surrounding the collusion between government and corporations
  • How divide and conquer tactics convince us to blame each other rather than the powers that oppress us

 

Download the Free Energy Balance Food Guide here: https://www.jayfeldmanwellness.com/guide/

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: 

https://jayfeldmanwellness.com/ep-103-how-western-culture-keeps-us-poor-and-destroys-our-family-community-and-relationships/

 

Timestamps:

1:34 – how western culture degrades safety and security through financial means

7:33 – how lower wages with higher costs reduces safety and forces people to prioritize work over quality of life

15:14 – we currently work more with less leisure time than ever before, with worse outcomes

20:24 – the cost of consumer culture and marketing as an engine that drives consumerism

30:53 – the cost of convenience culture: freedom, privacy, morals, ethics, and health

36:14 – the problems with profit-driven motives and the collusion between government and corporations

45:36 – how western society has become fragile and unstable

51:13 – how western culture degrades relationships and feelings of love and belonging

52:41 – continued how western culture degrades relationships and feelings of love and belonging

53:27 – divide and conquer tactics within western culture and encouraging the “us vs. them” mentality   

23 Nov 2021Ep. 75: Hormesis As An Anti-Scientific Defense For Industrial Pollution And Chemical Exposure (Hormesis Part 1)01:07:07
In this episode we discuss:
  • How the concept of hormesis defends our exposure to toxic chemicals, industrial contaminants and pollutants, and ionizing radiation

  • Why hormesis is a dangerous, anti-scientific idea masquerading as science

  • The suspicious history of hormesis and its current definitional problems 

  • The important distinction between stress and adaption

  • The problems with the terms “eustress” and “distress” 

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-75-hormesis-as-an-anti-scientific-defense-for-industrial-pollution-and-chemical-exposure-hormesis-part-1/ 

 

Timestamps:

3:36 – an introduction to hormesis as a means to reverse aging and reverse chronic health conditions 

6:45 – what is hormesis

12:34 – the suspicious history of hormesis  

16:20 – the definitional problems with hormesis

34:51 – how hormesis is influencing dangerous public health policies

47:35 – the difference between stressor effects and specific effects, creating a distinction between stress and adaptation, and the problems with the terms “eustress” and “distress”

 

15 Apr 2025Ep. 131: Should You Be Avoiding High Oxalate Foods? How To Fix Oxalate Issues01:15:19
In this episode we discuss:  
  • The impact of sugar consumption on oxalate production
  • Whether you really need to avoid all high oxalate foods
  • Different cooking and preparation methods to reduce oxalate exposure
  • Which supplements can make oxalate issues worse

 

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

 

The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/

 

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-131-whether-to-avoid-high-oxalate-foods-and-how-to-fix-oxalate-issues/

 

Timestamps:

0:00 – intro 

0:53 – whether fructose contributes to increased oxalate production 

3:42 – is sugar the culprit behind oxalate issues? 

9:14 – the problems with the research demonizing fructose 

14:45 – the optimal amount of dietary oxalate and how to determine whether oxalates are an issue for you 

17:57 – the importance of testing, experimentation, and listening to your symptoms 

25:10 – how to reduce your exposure to high-oxalate foods 

32:02 – the best cooking methods to reduce oxalates in food 

37:05 – foods highest in oxalates and whether salads are OK to eat 

40:17 – oxalate content in raw cacao vs chocolate 

45:26 – whether you need to avoid soybeans, potatoes, sweet potatoes, cassava, beets, and carrots due to their oxalate content 

49:05 – examples of bioenergetic diets with varying oxalate content 

57:01 – other dietary considerations for oxalate issues (PUFA, collagen, vitamin C, calcium, magnesium, carbohydrates, protein, and fat intake) 

1:06:22 – the best supplements to fix your oxalate issues  

1:11:45 – which supplements can make oxalate issues worse and whether to take probiotics for oxalate issues 

1:14:58 – the long-term impact of carnivore diets on liver and gut health

08 Jan 2024Ep. 107: Omega-3s DECREASE Lifespan and INCREASE Disease?01:09:55
In this episode we discuss:
  • Studies showing that omega-3 consumption decreases lifespan and increases disease processes 
  • The potentially harmful effects of omega-3 usage during pregnancy on offspring 
  • The impact of omega-3s on inflammation, endotoxin, and mitochondrial respiration 
  • The data in native cultures showing that omega-3 intake doesn’t improve cardiovascular disease or mortality 
  • Extremely healthy populations that consume high-carb and high-saturated fat diets with almost no omega-3s 

 

 

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

 

 

Download the Free Energy Balance Food Guide here: https://www.jayfeldmanwellness.com/guide/

 

 

Click here to check out the show notes: https:/jayfeldmanwellness.com/ep-107-omega-3s-decrease-lifespan-and-increase-disease

 

Timestamps:

0:00 – intro

1:30 – studies showing that omega-3 consumption decreases lifespan and increases disease processes in animals

13:55 – studies on animals showing the harmful effects of omega-3 consumption during pregnancy on offspring

17:37 – studies showing that omega-3 consumption contributes to disease processes, increases inflammation, causes oxidative stress, increases endotoxin, and interferes with mitochondrial respiration

29:23 – whether we should be concerned about saturated fats increasing endotoxin absorption

30:33 – how omega-3 consumption leaves us more susceptible to damage when we’re under stress

33:52 – whether we should be consuming fatty fish

37:00 – the lack of benefit of omega-3 consumption in native populations consuming large amounts of fatty fish and seafood

46:14 – low incidence of cardiovascular disease in native populations consuming very little omega-3s

1:05:18 – concluding thoughts on whether we should consume omega-3s based on the data on omega-3s in RBCs and phospholipids and mortality

11 Jul 2024Ep. 119: Vitamin A Toxicity: Examining the Evidence for Vitamin A Deficiency01:33:13
In this episode we discuss:
  • Whether vitamin A toxicity exists and is something you need to be worried about
  • Whether Grant Genereux’s claims about vitamin A deficiency are valid
  • Whether vitamin A is actually a poison rather than a vitamin
  • What we think about the current state of the Ray Peat forum
  • The research on vitamin A deficiencies and whether vitamin A deficiencies exist

 

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

 

Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/

 

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

 

The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/

 

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-119-vitamin-a-toxicity-examining-the-evidence-for-vitamin-a-deficiency

 

Timestamps:

0:00 – intro

1:09 – why we’re discussing vitamin A toxicity and Grant Genereux’s perspective

4:53 – closedmindedness within the “low vitamin A” sphere and how it compares to Ray Peat’s work

7:33 – how a low vitamin A diet can have benefits

9:27 – cautioning against the idea of "detox" as an excuse for negative effects and vitamin A toxicity as an unfalsifiable hypothesis

12:33 – the importance of evaluating information objectively while avoiding censorship, tribalism, fearmongering, and religiosity

21:17 – concerns with the current state of the Ray Peat Forum and how to recognize unsubstantiated claims

26:45 – Grant's initial critiques of the original studies on vitamin A deficiency are extremely weak and unsubstantiated

41:48 – introducing Wolbach’s 1925 study on vitamin A deficiency

45:47 – refuting Grant's argument that the retinoic acid in the vitamin-free casein would have caused toxicity

52:35 – refuting Grant's argument regarding confounding variables in lard and butter

1:02:53 – research on vitamin A deficiency and whether vitamin A deficiencies exist

1:20:32 – the necessity of vitamin A for pregnancy, fetal growth, and development

02 Dec 2021Ep. 76: Why Caloric Restriction Is NOT Responsible For Lifespan Extension (Hormesis Part 2)01:40:32
In this episode we discuss:
  • How the largest body of evidence cited in favor of hormesis actually doesn’t support it at all

  • Why caloric restriction is NOT responsible for slowing aging and extending lifespan (and what is actually responsible)

  • The many factors that confound the calorie restriction research (including differences between organisms, poor research design, amino acid restriction, PUFA, endotoxin, and more)

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-76-why-caloric-restriction-is-not-responsible-for-lifespan-extension-hormesis-part-2/ 

 

Timestamps:

3:36 – the physiology of hormesis and the general support for hormesis

12:54 – outlining the problems with hormesis

18:51 – how differences between organisms confound the caloric restriction research 

37:34 – the problem with using proxy markers to evaluate health effects and the importance of context

48:20 – how differences between organisms confound the caloric restriction research (cont.)

51:58 – how hydration status and macronutrient ratios confound the caloric restriction research

55:57 – how the myopic hormetic view leads to the ignorance of many confounding variables

1:02:00 – how the restriction of particular amino acids, ad libitum feeding, and a refined diet confound the caloric restriction research

1:11:58 – how PUFA confounds the caloric restriction research

1:30:09  – how endotoxin and gut health confound the caloric restriction research

 

12 Oct 2020Ep. 29: Cholesterol Part 1: Statin Dangers and Whether Cholesterol Causes Heart Disease00:47:01
In this episode we discuss:
  • ​Where the mainstream view that high cholesterol levels cause heart disease went wrong
  • Why we may want to reconsider statin use for the vast majority of cases
  • Why we don’t need to avoid high-cholesterol foods, even if we have high cholesterol levels
  • The protective, beneficial effects of cholesterol
  • What actually increases cholesterol levels and why statins don’t effectively address these factors
  • Why the cholesterol-lowering drugs are often more harmful than helpful
  Sign up for the free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy/   Click here to check out the show notes: https://jayfeldmanwellness.com/ep-29-cholesterol-part-1-statin-dangers-and-whether-cholesterol-causes-heart-disease/
02 Nov 2020Ep. 32: The Causes of Hypertension And Nutrition as a Solution (Blood Pressure Part 2)00:46:36
In this episode we discuss:
  • ​What actually causes high blood pressure and why the mainstream guidelines do little to address these causes
  • Why hypertension is a protective, adaptive response
  • The physiology of a dysfunctional vascular system and the involvement of swelling/edema, fibrosis, and calcification
  • Whether the blood pressure medications address the causes of hypertension and are the best option for its treatment
  • Nutrients that improve hypertension and foods to avoid that worsen vascular health​
  Sign up for the free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy/   Click here to check out the show notes: https://jayfeldmanwellness.com/ep-32-the-causes-of-hypertension-and-nutrition-as-a-solution-blood-pressure-part-2/
10 Aug 2020Ep. 20: Intuitive Eating, 5,000 Calories per day, and Whether to go “All In”01:11:01
In this episode we discuss:
  • Why “all in” and intuitive eating work for upregulating our metabolism
  • Where these eating methods fall short and how the same benefits can be achieved without many of the negative symptoms
  • Why what we eat matters and may be more important than how much
  • ​How we can turn off excessive hunger by understanding how our hunger signals work
  • Why eating intuitively works well if we’re eating the right types of foods (and which foods are the “right ones”)
  Sign up for the free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy/   Click here to check out the show notes: https://jayfeldmanwellness.com/ep-20-intuitive-eating-5000-calories-per-day-and-whether-to-go-all-in/
25 Jan 2021Ep. 44: Pro-Metabolic Nutrition for Autoimmune Conditions (Autoimmunity Part 3)00:47:03
In this episode we discuss:
  • The problem with using fish oil and omega-3s to decrease inflammation

  • How to lower the stress hormones with carbohydrates and why this is key for autoimmune conditions

  • Why fasting and low-calorie diets make autoimmune conditions worse in the long run

  • Why reducing PUFA consumption is paramount for autoimmune conditions

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-44-pro-metabolic-nutrition-for-autoimmune-conditions-autoimmunity-part-3/

 

Timestamps:

3:03 – the importance of eating enough food and not fasting for autoimmune conditions

8:27 – the effects of PUFA (omega-3s and omega-6s) on autoimmune conditions

34:57 – the importance of carbohydrate supply and blood sugar stability for autoimmune conditions

 
30 Apr 2024Ep. 114: Fat-Burning Drives Insulin Resistance And Eating Carbohydrates Improves Insulin Sensitivity00:56:49
In this episode we discuss:
  • How increasing carbohydrate intake actually improves insulin sensitivity, even in people with type 2 diabetes 
  • The research showing that fatty liver disease and cardiovascular disease are both characterized by excess fatty acid oxidation 
  • The research showing that fatty liver disease and cardiovascular disease are both characterized by excess fatty acid oxidation 
  • Why strategies such as intermittent fasting, cold plunges, and OMAD (one meal a day) are not effective for improving insulin sensitivity 

 

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

 

Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/

 

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

 

The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/

 

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-114-fat-burning-drives-insulin-resistance-and-eating-carbohydrates-improves-insulin-sensitivity/

 

Timestamps:

0:00 – intro

1:17 – stress hormones (glucagon, epinephrine, and cortisol) are major contributors to insulin resistance and diabetes 

4:05 – elevated glucagon levels, not carbohydrates, are the driving force behind high fasting blood glucose levels

6:43 – glucagon is a driver of insulin resistance, while insulin is just a symptom

12:46 – the research showing that blocking stress hormones directly improves insulin sensitivity

15:14 – “hormetic” stressors like intermittent fasting, cause insulin resistance

19:30 – fat burning drives insulin resistance and keeps us in a catabolic state, driving weight gain and muscle wasting 

22:15 – cortisol drives insulin resistance and why serum cortisol levels don’t provide the full picture

25:00 – low-carb diets reduce insulin sensitivity while carbohydrate intake improves it 

29:40 – decreasing fatty acid oxidation by increasing carb intake improves our ability to tolerate carbohydrates

33:46 – burning fat contributes to increased disease processes and does not lead to losing more body fat

38:04 – fatty acid oxidation damages our mitochondria and increases fat storage

46:22 – type 2 diabetes directly contributes to heart disease by upregulating fatty acid oxidation 

52:05 – how to decrease fatty acid oxidation and improve glucose metabolism

30 Oct 2024BV#3: Georgi Dinkov Responds To Estrogen Criticism, Serotonin Confusion, & Low Thyroid On Carnivore02:17:53

In this episode we discuss:

  • The criticism of Georgi regarding estrogen and cancer
  • The major point that Siim Land is missing when it comes to increasing NAD+
  • Why we think Dr. Berg is completely wrong on serotonin
  • Nutrition With Judy’s suggestion that thyroid issues on a carnivore diet are not caused by the lack of carbohydrates, and why we think this isn’t the case
  • Dave Asprey’s recommendation to drink orange juice and whether it’s for the right reasons

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

 

The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/

 

Danny's Telegram: https://t.me/dannyroddy

 

Timestamps:

0:00 – intro

1:10 – whether estrogen is a carcinogen 

6:13 – estrogen’s role in driving weight gain and chronic diseases such as cancer, Alzheimer’s disease, and Type 2 Diabetes 

8:03 – the dangers of synthetic progesterone (progestin) use 

10:14 – the difference between estrone and estradiol and the problems with estrogen testing 

16:14 – whether estrogen therapy should be used in post-menopausal women 

17:17 – the difference between oral and transdermal estrogen use 

24:44 – the connection between inflammation and estrogen production 

27:57 – why estrogen levels are not actually low in post-menopausal women 

37:59 – our take on Siim Land's post on NAD+ and mitochondrial uncoupling 

48:25 – why intentionally seeking hormetic responses, like the activation of heat-shock proteins, should be avoided 

50:37 – which form of CoQ10 is better: ubiquinone or ubiquinol 

53:34 – what Siim Land and many others get wrong when it comes to raising NAD+  

55:44 – does fasting and AMPK upregulation cause cancer? 

1:00:29 – fat fuels cancer and why not to restrict sugar for cancer 

1:09:56 – Dr Berg’s take that serotonin is the “happy hormone” – why we disagree 

1:19:06 – serotonin’s role in driving chronic diseases and conditions including depression, anxiety, IBS, and cancer 

1:27:24 – Nutrition with Judy claims that the low thyroid levels generally seen on the carnivore diet have nothing to do with a lack of carbohydrates 

1:39:01 – how the rate of living theory changed mainstream medicine’s view that thyroid health is important 

1:45:37 – how excessive exercise raises stress hormones, setting you up for weight regain 

1:51:30 – why the combination of fasting and exercise is detrimental to our health 

1:53:44 – how estrogen is used to fatten animals  

2:02:42 – why Dave Asprey is talking about endotoxin and orange juice 

2:07:00 – whether the sugar in orange juice feeds bacteria and increases endotoxin 

2:09:40 – why the low-carb trend keeps resurfacing, despite the growing evidence against it 

2:14:41 – where to find Georgi and IdeaLabs 

03 Mar 2022Ep. 81: Whether Intense Exercise and Endurance Training Should Be Avoided (Fitness vs. Health Part 2)01:10:51
In this episode we discuss:
  • How to determine how much exercise is right for you

  • Why working out regularly is not enough to make up for sitting all day

  • Why fitness and health are not synonymous

  • Whether lactic acid production, breathlessness, and fat oxidation due to exercise should be avoided at all costs

  • Whether intense exercise and being highly active is always more harmful than helpful

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-81-whether-intense-exercise-and-endurance-training-should-be-avoided-fitness-vs-health-part-2/ 

 

Timestamps:

2:55 – the benefits of movement and exercise 

6:41 – whether intense exercise involving lactate production and heavy breathing/breathlessness is harmful 

10:13 – whether endurance training involving fat oxidation is harmful 

18:31 – drawing a line between fitness and health 

25:06 – how to determine how much exercise is right for you

38:23 – whether intense exercise and being highly active is always more harmful than helpful

43:33 – why “eat less and exercise more” doesn’t work and ignores major aspects of our physiology 

 

01 Apr 2021Ep. 53: Supplements To Boost Testosterone and Increase Metabolism (Men’s Hormonal Health Part 5)00:56:45
In this episode we discuss:
  • Which protein powders are ideal and when it’s best to use them

  • Which supplements can help to boost testosterone, increase muscle mass, and raise our metabolism

  • Whether hormone tests are necessary or helpful

  • When it makes sense to supplement with hormones and factors to consider when doing so

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Sign up for a free call here: https://jayfeldmanwellness.com/call

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-53-supplements-to-boost-testosterone-and-increase-metabolism-mens-hormonal-health-part-5/

 

Timestamps:

3:52 – ideal protein powders and when it’s best to use then

14:38 – the problems with fish oil and omega-3s

19:34 – using vitamins A, D, E, and K to improving hormonal health

26:35 – using BCAAs, taurine, glycine, and other amino acids to support liver health, muscle building, and hormonal health

31:04 – the various benefits of using creatine and whether it’s necessary to supplement

34:28 – energy is at the core of hormonal health

38:45 – why hormone tests must be considered in context and other indicators that can be used to gauge hormonal health

43:33 – when to supplement with exogenous hormones and factors to consider when doing so

 

04 May 2020Ep. 6: Blood Sugar Part 3: The Best Sugar Sources00:52:19

In this episode we discuss:

  • ​The best fruits and why quality is so important
  • ​Why fruit juices are great sugar sources and berries aren’t the “holy grails” of fruits
  • ​The differences between honey, table sugar, and corn syrup
  • ​Why table sugar is not “toxic” or a “poison” but still may be problematic
  • ​Why white sugar is better than “raw” sugar
  • ​How much sugar/carbohydrates we should be eating for optimal health

Sign up for the free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy/

    Click here to check out the show notes: https://jayfeldmanwellness.com/ep-6-blood-sugar-part-3-the-best-sugar-sources/
04 Jun 2024Ep. 117: Fructose Malabsorption, Protecting Against Alcohol, & Brain Injuries and Inflammation (Q & A)01:03:29
In this episode we discuss:
  • Concerns surrounding fructose malabsorption and whether fructose is really a FODMAP
  • Whether you need to be concerned about excess fructose in foods
  • Whether you should avoid sugar and supplement with fish oil for brain inflammation
  • Diet and supplement strategies for brain injuries
  • The impacts of drinking alcohol from the Bioenergetic view

 

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

 

Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/

 

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

 

The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/

 

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-117-fructose-malabsorption-protecting-against-alcohol-and-brain-injuries-and-inflammation-q-and-a

 

Timestamps:

0:00 – intro

1:15 – how fructose gets absorbed in the small intestine

4:24 – the optimal fructose to glucose ratio and how to tell if you have fructose malabsorption

8:41 – the details of how glucose helps with fructose absorption

12:04 – which foods have a high fructose to glucose ratio

16:24 – issues with FODMAP categorization and whether fructose is really a FODMAP

21:23 – listening to your body and understanding individual context vs following rigid “food rules”

27:39 – anti-inflammatory diets and whether we should avoid sugar and supplement with fish oil to reduce brain inflammation

32:06 – dietary and supplement strategies to promote an anti-inflammatory state in the brain

39:15 – the effectiveness of red-light therapy, methylene blue, progesterone, exogenous ketones, and polyphenols in treating brain injuries

44:31 – why we don’t want to prioritize omega 3s in the diet and whether eating fish is any better than fish oil supplementation

47:21 – reducing inflammation with the use of aspirin

47:53 – the main concerns with drinking alcohol: intestinal permeability, endotoxin production, and liver health

52:32 – stress-relieving supplement alternatives to alcohol and the effects of alcohol on vitamins and minerals

54:37 – strategies to mitigate the effects of alcohol in the short-term

58:14 – whether it makes sense to drink alcohol, alcohol use as a coping mechanism, and the impact of culture

1:00:07 – more strategies for mitigating the effects of alcohol in the short and long term

29 Dec 2020Ep. 40: Why Estrogen and Birth Control Are Not The Solution (Women’s Hormonal Health Part 1)01:03:41
In this episode we discuss:
  • Why estrogen dominance is one of the primary drivers of reproductive issues for women
  • The cost of suppressing hormonal and reproductive symptoms with birth control
  • Whether symptoms like breast soreness, bloating, cramps, heaviness, mood swings, migraines, PCOS, fibroids, and endometriosis can be resolved by correcting underlying dysfunction
  • Why estrogen is not the “female hormone” and is instead better classified as a stress hormone
  • The healthiest form of birth control/contraception

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-40-why-estrogen-and-birth-control-are-not-the-solution-womens-hormonal-health-part-1/

  Timestamps:  

0:00 – intro

3:13 – the influence of industry in the perception of estrogen and birth control

18:18 – the harmful effects of estrogen and birth control

24:29–the balance between estrogen and progesterone and considering estrogen dominance as a major driver of reproductive issues for women

29:10 – the cost of the conventional medical approach to female hormonal health and reproduction

53:47 – the healthiest alternatives to hormonal birth control/contraception and using menstrual cycles as indicators of health status

 
19 Oct 2020Ep. 30: Cholesterol Part 2: How to Lower Your Cholesterol And Heart-Healthy Fats00:50:07
In this episode we discuss:
  • ​What actually causes plaque buildup (and why cholesterol isn’t the culprit)
  • Why omega-3s and omega-6s aren’t the heart-healthy fats
  • How you can lower cholesterol levels in a healthy way
  • Why eating lots of whole grains, nuts and seeds, vegetable oils, and fatty fish like salmon isn’t the way to go for heart health
  • The importance of gut and thyroid health for lowering cholesterol
  Sign up for the free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy/   Click here to check out the show notes: https://jayfeldmanwellness.com/ep-30-cholesterol-part-2-how-to-lower-your-cholesterol-and-heart-healthy-fats/
18 Aug 2020Ep. 21: Drink Less Water And Eat More Salt (And How to Address High Blood Pressure)01:07:06
In this episode we discuss:
  • Why drinking lots of water isn’t an effective solution for headaches, better skin, flushing out toxins, boosting our immune system, reducing swelling, or increasing our metabolism
  • Why eating less salt isn’t a good option for lowering blood pressure and what you can do instead to resolve hypertension
  • How drinking too much water and eating too little salt causes stress
  • ​How eating more salt and less water can reduce swelling and water retention
  • The best indicators for our water and salt needs
  Sign up for the free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy/   Sign up for a free call here: https://jayfeldmanwellness.com/call   Click here to check out the show notes: https://jayfeldmanwellness.com/ep-21-drink-less-water-and-eat-more-salt-and-how-to-address-high-blood-pressure/
24 Aug 2023Ep. 100: Building a Bioenergetic Diet: Macros, Calories, and Meal Timing01:04:12
In this episode we discuss:
  • Optimal macronutrient breakdowns for meals and snacks
  • How to calculate your protein, carbohydrate, and fat needs
  • How to use taste, cravings, hunger, and experimentation to guide your macro intake
  • How to find your starting calorie intake
  • The optimal number of meals and snacks to have in a day

 

Download the Free Energy Balance Food Guide here: https://www.jayfeldmanwellness.com/guide/

 

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

 

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-100-building-a-bioenergetic-diet-macros-calories-and-meal-timing/

 

Timestamps:

0:00 – intro 

1:21 – context for these dietary guidelines and the importance of the “why” 

7:58 – guidelines for optimal protein intake from the bioenergetic view 

14:46 – guidelines for optimal fat intake from the bioenergetic view 

29:27 – guidelines for optimal carb intake from the bioenergetic view  

31:32 – how to find your starting calorie intake 

35:29 – guidelines for optimal carb intake from the bioenergetic view (continued) 

42:00 – using taste, cravings, hunger, and experimentation to adjust these guidelines 

45:35 – guidelines for optimal meal and snack timing and composition from the bioenergetic view 

 

28 Jun 2021Ep. 63: Why Fructose Does NOT Cause Fatty Liver (NAFLD Part 1)01:15:07
In this episode we discuss:
  • Why fructose does not cause fatty liver

  • The 3 major problems with the research suggesting that fructose causes fatty liver

  • How fat production in the liver can be protective

  • The role of PUFA and endotoxin in de novo lipogenesis and inflammation

  • Why overeating is not the cause fatty liver

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-63-why-fructose-does-not-cause-fatty-liver-nafld-part-1/ 

 

Timestamps:

3:54 – an introduction to non-alcoholic fatty liver disease (NAFLD)

15:34 – the basics of fat production in the liver

17:24 – what happens to carbohydrates when they reach the liver

20:16 – the basics of why fructose doesn’t cause fatty liver

26:24 – the details of why fructose doesn’t cause fatty liver

47:11 – what actually happens when humans consume fructose, even in large amounts

55:15 – whether low-calorie diets or avoiding fructose and saturated fats are practical dietary strategies

1:09:52 – what actually happens when humans consume fructose, even in large amounts (cont.)

 

26 Oct 2020Ep. 31: Mineral Balance and Energy are the Keys to Regulating Blood Pressure (Blood Pressure Part 1)01:14:06
In this episode we discuss:
  • ​Why low-sodium diets and drinking lots of water aren’t the solution for hypertension
  • How blood pressure medications work and why they don’t solve the underlying causes of high blood pressure
  • How much salt someone should be consuming if they have high blood pressure (it’s probably more than you think)
  • The relationships between the various electrolytes (sodium, potassium, magnesium, calcium)
  • How salt opposes stress
  • Why the heart may not function as a pump and how energy can drive circulation and oxygenation
  Sign up for the free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy/   Click here to check out the show notes: https://jayfeldmanwellness.com/ep-31-mineral-balance-and-energy-are-the-keys-to-regulating-blood-pressure-blood-pressure-part-1/
05 Oct 2020Ep. 28: Restoring Gut Health, Why Not to Use Probiotics, and Ray Peat’s Carrot Salad (Q & A)00:51:38
In this episode we discuss:
  • ​How to restore gut health after antibiotics or antifungals
  • Whether the Ray Peat inspired carrot salad is an effective antibiotic
  • Why probiotics may not be a good idea for maintaining or replenishing your gut microbiome (and what to do instead)
  • How to keep your bowels regular and improve gut motility
  • Simple tips to make healthy eating easier
  Sign up for the free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy/   Sign up for a free call here: https://jayfeldmanwellness.com/call   Click here to check out the show notes: https://jayfeldmanwellness.com/ep-28-restoring-gut-health-why-not-to-use-probiotics-and-ray-peats-carrot-salad/
21 Dec 2020Ep. 39: Nutrition For a Compromised Gut, Food Additives, & Skincare Products (Q & A)01:00:48
In this episode we discuss:
  • How to eat more food when your gut is compromised
  • How to support your digestion and restore gut health using nutrition and supplements
  • Whether food excipients like citric acid, ascorbic acid, and soy lecithin should be avoided
  • Why body odor and skin care needs depend on our health state
  • Which personal care ingredients to use and avoid
  • Why beauty care and skincare products aren’t the solution for skin symptoms like acne, dry skin, rosacea, eczema, and psoriasis
  Sign up for the free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy/   Click here to check out the show notes: https://jayfeldmanwellness.com/ep-39-nutrition-for-a-compromised-gut-food-additives-skincare-products-q-a/   Timestamps:  

3:11 – what to eat when your gut health is compromised; how to navigate compromised gut health

12:22 – supplements that can help restore gut health

22:58 – the harmful effects of food excipients like citric acid, ascorbic acid, and soy lecithin, and whether they’re worth avoiding

31:45 – Mike’s personal care routine

37:16 – why personal care, skincare, and beauty care products can be more harmful than helpful

43:56 – Jay’s personal care routine and moisturizing ingredients

46:25 – personal care products/companies and ingredients to use or avoid

49:14 – personal care products generally don’t solve the underlying problems that lead to skin symptoms in the first place

55:07 – other important considerations for personal care and cleaning products

 
24 Jul 2023Ep. 96: Avoid Low-Carb Diets, Fasting, and Caloric Restriction If You Have Hypothyroidism (Hypothyroidism Part 2)01:31:03
In this episode we discuss:
  • The factors that affect thyroid hormone production, conversion, transport, and uptake

  • How high TSH levels cause damage to the thyroid gland

  • High-carb diets vs. low-carb diets for thyroid health

  • Why restricting calories is not the way to go if you’re struggling with hypothyroidism

  • The effects of PUFA and endotoxin on thyroid hormone activity

  • The problems with both deficiencies and excesses of iron, iodine, and vitamin A for thyroid health

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-96-avoid-low-carb-diets-fasting-and-caloric-restriction-if-you-have-hypothyroidism-hypothyroidism-part-2/

 

Timestamps:

0:00 – intro 

1:28 – the factors that affect thyroid hormone production, conversion, transport, and uptake

3:45 – the impact of stress on thyroid hormone production and conversion 

5:02 – how the stress hormones and inflammatory cytokines affect thyroid hormone production and conversion

16:44 – thyroid hormones increase sensitivity to stress hormones 

21:44 – elevated free fatty acids, especially PUFA, inhibit thyroid hormone binding

23:26 – how a lack of energy prevents the cells from taking up thyroid hormone

30:00 – how oxidative stress affects thyroid hormone production and the effects of TSH on oxidative stress

38:25 – how a low-carb diet affects thyroid hormone production and conversion, causing a hypothyroid state; high-carb diets vs. low-carb diets for thyroid health

47:46 – insulin resistance is associated with reduced thyroid hormone conversion, but this doesn’t mean you should avoid carbohydrates  

51:39 – how caloric restriction affects thyroid status

55:04 – the effects of fasting on thyroid status

56:42 – T3 has positive feedback on its own production and what this means for thyroid hormone replacement

1:00:01 – the effects of PUFA and endotoxin on thyroid hormone activity

1:04:30 – the effects of micronutrients, specifically iron, vitamin A, selenium, and iodine, on thyroid hormone production, conversion, and activity

1:16:30 – increased thyroid activity increases macronutrient and micronutrient needs, but also improves micronutrient retention in the long-term

1:19:15 – the effects of environmental toxins (pesticides, industrial chemicals, heavy metals, etc.) on thyroid hormone production, conversion, and activity

1:25:20 – the effect of sleep on thyroid hormone production and conversion 

24 May 2024Ep. 116: The TRUTH About LDL And Heart Disease: LMHR & The Lipid Energy Model01:33:58
In this episode we discuss:
  • The validity of the counterarguments against the Lipid Energy Model
  • Whether the Lipid Energy Model means that high LDL does not increase cardiovascular disease risk
  • How thyroid and metabolism relate to high LDL on a low-carb diet
  • What the Lean Mass Hyper-Responder phenotype means in terms of metabolic health
  • Whether low-carb diets are ideal for cardiovascular disease health and health in general

 

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

 

Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/

 

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

 

The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/

 

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-116-the-truth-about-ldl-and-heart-disease-lmhr-and-the-lipid-energy-model/

 

Timestamps:

0:00 – intro

1:17 – the primary counterarguments against the Lipid Energy Model 

4:15 – BMI, not saturated fat, correlates with the LMHR phenotype 

8:15 – eating carbs dramatically lowers cholesterol in LMHR 

11:14 – whether Oreos are more effective at lowering cholesterol than statins 

17:30 – high cholesterol levels in the LMHR phenotype are not due to excess saturated fat intake or cholesterol production 

19:25 – prominent cardiologists and researchers dismissing the lipid energy model due to dogmatism interferes with progress in science and medicine 

24:40 – Dr. Shawn Baker’s carbohydrate experiment and contextual considerations when reintroducing carbs into the diet 

28:46 – further support for the lipid energy model and the relationship with thyroid function 

33:32 – the difference between saturated, monounsaturated, and polyunsaturated fats in relation to lipid profiles 

34:40 – whether LDL cholesterol and ApoB cause heart disease and plaque formation 

42:18 – how the Lipid Energy Model helps uncover the underlying cause of heart disease 

45:15 – LDL levels as a marker of metabolic health rather than a cause of cardiovascular disease and why we may not always want to lower LDL 

55:02 – evidence suggesting that LDL does not drive cardiovascular disease 

1:05:43 – the difference between high LDL due to metabolic dysfunction and high LDL due to a low-carb diet 

1:09:58 – lipid values don’t tell us the whole picture: the Kitavans 

1:16:54 – why decreases in insulin, glucose, and HbA1C as well as increased lipolysis and fat oxidation on a low-carb diet is not necessarily a sign of improvement 

1:22:57 – increased lipolysis on low-carb diets does not lead to body-fat loss 

1:24:25 – whether the Lipid Energy Model proves that low-carb diets are optimal for health

06 Apr 2020Ep. 1: Energy is Everything00:46:10

In this episode we discuss:

  • Why energy is at the center of our health and virtually all symptoms and conditions 
  • ​The various factors that affect our body’s ability to produce energy from the food we eat 
  • ​Why too much exercise can be harmful 
  • ​Why burning more calories isn’t the answer for fat loss or health 
  • ​Where the calories-in/calories-out equation went wrong and how it leads to a low metabolism
  • ​The different types of energy production (and which one we want to favor to improve out health) 
  • ​The hormones that govern our energy systems

 

Sign up for the free Energy Balance Mini Course here: https://jayfeldmanwellness.com/energy/

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-1-energy-is-everything/

13 May 2022Ep. 83: How Nutrient Partitioning Affects Eating Behavior and Fat Loss01:20:49
In this episode we discuss:
  • How our bodies partition nutrients and why this matters for optimizing our health

  • Why hyperpalatable food and stress-eating are not the primary drivers of overeating

  • How being sedentary can mimic starvation and excess stress

  • How excessive fat-burning causes metabolic derangement and overeating 

  • Why an energetic deficit is not required for fat loss and instead causes fat gain 

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-83-how-nutrient-partitioning-affects-eating-behavior-and-fat-loss/ 

 

Timestamps:

2:48 – overview of the study we’ll be discussing

6:21 – why excess energy and overeating don’t cause fat gain

13:59 – the flow of energy through our metabolic systems determines health

18:25 – insulin resistance is an adaptive process that allows for nutrient partitioning

22:31 – insulin resistance occurs in stress states, such as caloric restriction, fasting, and low-carb diets, to divert fuel to the most essential tissues 

29:24 – hunger and appetite are determined by the amount of energy available, not number of calories taken in

47:46 – physical inactivity results in the same harmful metabolic effects as starvation and excess exercise

56:31 – hyperpalatable sugar- and fat-containing foods do not cause obesity

1:00:26 – other factors that affect nutrient partitioning

1:09:46 – considerations to keep in mind when reading and evaluating research

1:13:35 – why an energetic deficit is not required for fat loss

 

17 Jun 2021Ep. 62: Diving in to the Bioenergetic View and Our Mistakes Along the Way (Our Health Journeys Part 2)01:32:05
In this episode we discuss:
  • The many mistakes we made after finding Ray Peat and the bioenergetic view

  • Our re-feeding periods that involved eating over 5,000 calories and 700g of carbs per day

  • Our experimentation with various supplements (thyroid, B vitamins, fat-soluble vitamins, pro-metabolic hormones, antibiotics, methylene blue, inosine) and what we learned along the way

  • How long it took for us to see major improvements and stability in our health (it’s probably longer than you think)

  • Why nutrition alone is not enough for optimal health (and what other factors we should consider)

  • Our experiences in authoritarian environments (especially within the education system) and working to shed dogmatism

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-62-diving-in-to-the-bioenergetic-view-and-our-mistakes-along-the-way-our-health-journeys-part-2/ 

 

Timestamps:

4:11 – going all-in on a bioenergetic, Ray Peat inspired diet and experimenting with milk and low-fat diets

17:28 – Mike’s journey with milk, a carnivore diet, and refining his bioenergetic diet

26:40 – Jay’s lingering issues and experiments that helped resolve them

33:53 – Mike’s continued experimentation and the factors outside of nutrition that had major impacts on his health

46:49 – Jay’s continued experimentation and how stress and a lack of sleep affected his health

53:03 – creating an optimal environment is always a work in progress

59:19 – Mike’s depressive period following college and Jay’s experience with depression

1:06:06 – our experiences in authoritarian environments (especially within the education system) and working to shed dogmatism

1:20:51 – the value of intuition and listening to how you feel as well as working to understand the physiology

 

22 Mar 2021Ep. 52: Workout Supplements To Avoid & Decreasing Stress (Men’s Hormonal Health Part 4)01:08:06
In this episode we discuss:
  • How stress can decrease muscle mass, increase body fat, and disrupt our hormones

  • How you can decrease and manage stress to improve hormonal health

  • Whether popular fitness like supplements nitric oxide boosters, pre-workouts, and intra-workout carbohydrates are supportive on the bioenergetic level

  • Why supplements are not the answer for improving body composition and hormonal health and when it makes sense to use supplements

  • Why most weight loss supplements and “fat-burners” are not a good idea and what can be done instead to lose fat

  • Whether it makes sense to use exogenous hormones to improve our hormonal state

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Sign up for a free call here: https://jayfeldmanwellness.com/call

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-52-workout-supplements-to-avoid-decreasing-stress-mens-hormonal-health-part-4/

 

Timestamps:

3:58 – the impact of stress on muscle mass, body fat, and hormonal health

11:17 – how to decrease and manage stress

25:52 – popular supplements used for building muscle, losing fat, and improving hormones that are best avoided

30:47 – why supplements are not the answer for improving body composition and hormonal health

36:36 – whether nitric oxide boosters, pre-workouts, and intra-workout carbohydrates are supportive on the bioenergetic level

49:15 – whether weight loss supplements and “fat-burners” are a good idea for losing body fat and what can be done instead

56:48 – whether it makes sense to use exogenous hormones to improve the hormonal state

 

31 Aug 2020Ep. 23: How to Slow Aging Part 1: Increasing Your Metabolism And Competing Theories00:58:12

In this episode we discuss:

  • Why increasing our metabolism allows us to age slower and live longer
  • Why PUFA oppose health, shorten lifespan, and drive aging
  • The role of free radicals and oxidative stress in aging
  • Why the current views of aging are incomplete
  • The problems with aging and lifespan research and how this has lead to misguided recommendations

 

Watch this episode on Youtube here: https://youtu.be/Vmle5ksNQ9o

 

Sign up for the free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy/

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-23-how-to-slow-aging-part-1-increasing-your-metabolism-and-competing-theories/

15 Oct 2021Ep. 72: Dental Health on a High-Sugar Diet & How To Determine What’s Blocking Energy Production (Q & A)00:58:27
In this episode we discuss:
  • Which vitamins and minerals are most relevant to dental health

  • How our gut health and microbiome can affect oral health 

  • How to prevent potential dental harm on a high-sugar diet/from consuming fruits and other sugar-containing foods  

  • How to determine the order of operations for making lifestyle adjustments 

  • The first step to addressing virtually all health issues

 

Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy

 

Click here to check out the show notes: https://jayfeldmanwellness.com/ep-72-dental-health-on-a-high-sugar-diet-how-to-determine-whats-blocking-energy-production-q-a/ 

 

Timestamps:

2:49 – factors to consider for supporting dental health and preventing tooth erosion and decay

23:10 – how to determine the order with which to address different aspects of health to address first and how to determine what’s blocking our energy production

 

13 Feb 2025Ep. 128: Are Oxalates the Problem, or Is It Your Gut?01:31:02
In this episode we discuss:
  • Whether the harmful effects of oxalates are legitimate or overblown

  • How your gut health impacts your susceptibility to oxalate issues

  • Which nutrients help decrease oxalate absorption

  • How fat digestion relates to oxalate absorption

  • Whether a candida overgrowth may be at the root of your oxalate issues

 

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

 

The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/

 

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-128-are-oxalates-the-problem-or-is-it-your-gut/

 

Timestamps:

0:00 – intro 

1:08 – common misconceptions about oxalates and whether oxalate concerns are justified

5:21 – symptoms often attributed to oxalates and whether they are truly responsible for most health problems

12:48 – what are oxalates? 

16:18 – oxalates cause kidney damage and reduce mineral bioavailability

21:34 – oxalates and cardiovascular disease

24:43 – oxalates as a driver of gut dysbiosis and decreased bile acid production

29:16 – metabolic damage caused by oxalates

37:06 – how a low-PUFA diet and vitamin E can protect against oxalate damage

43:19 – high oxalate foods and factors that impact oxalate absorption

53:29 – soluble vs. insoluble oxalates

57:04 – how calcium affects oxalate absorption and the impact of parathyroid hormone and 1,25-Dihydroxyvitamin D

1:07:41 – the effects of magnesium on oxalate absorption

1:12:44 – how deficiencies in vitamin B1 (thiamine) and vitamin B6 can increase oxalate levels

1:14:44 – how gut health relates to oxalate issues (fat digestion, intestinal permeability, and oxalate degrading bacteria)

1:22:23 – “oxalate dumping” on low-carb diets and carnivore diets may be due to poor gut health

1:26:15 – whether candida infections or other fungal infections cause excess oxalate production

20 Apr 2020Ep 4: Blood Sugar Part 1: Blood Sugar Regulation and Energy Balance00:42:43

In this episode we discuss:

  • ​The relationship between our blood sugar and energy balance
  • ​Why sugar and other carbohydrates are some of the most protective, anti-stress compounds
  • ​How insulin helps to ​lower stress hormones
  • ​Why “lowering blood sugar” isn’t a good goal for improving health
  • ​Why protein doesn’t “stabilize our blood sugar”
  • ​Why diabetes is NOT caused by elevated insulin or blood sugar levels

Sign up for the free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy/

    Click here to check out the show notes: https://jayfeldmanwellness.com/ep-4-blood-sugar-part-1-blood-sugar-regulation-and-energy-balance/
27 Jul 2020Ep. 18: How to Fix Your Sleep Part 2: Nutrition, Supplements, and Routines01:05:56
In this episode we discuss:
  • Why eating enough of the right nutrients is vital to improving sleep (and which of these nutrients are most important)
  • Why avoiding carbs or fats is one of the worst things you can do for your sleep
  • The best supplements to help you fall asleep and stay asleep (and which ones to watch out for)
  • How eating the right foods before bed and in the morning can improve our sleep
  Sign up for the free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy/   Click here to check out the show notes: https://jayfeldmanwellness.com/ep-18-how-to-fix-your-sleep-part-2-nutrition-supplements-and-routines/
18 Apr 2024Ep. 113: Carbohydrates Don’t Cause Insulin Resistance or Diabetes; Evidence For The Bioenergetic View00:54:41
In this episode we discuss:
  • Insulin resistance and type 2 diabetes are diseases of excess fat burning and impaired glucose metabolism
  • How increasing carbohydrate intake improves insulin sensitivity, even in people with type 2 diabetes
  • Evidence supporting the bioenergetic view of insulin resistance and type 2 diabetes
  • Why carbs are not actually the cause of insulin resistance and diabetes

 

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

 

Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/

 

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

 

The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/

 

Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-113-carbohydrates-dont-cause-insulin-resistance-or-diabetes-evidence-for-the-bioenergetic-view

 

Timestamps:

0:00 – intro

1:28 – what the mainstream view of insulin resistance gets wrong when it comes to what causes insulin resistance and diabetes

3:24 – glycolysis and fat oxidation are favored, and glucose oxidation is inhibited in insulin resistance and diabetes

8:39 – what happens to glucose in diabetic cells

10:32 – why insulin resistance is a symptom rather than the driver of diabetes

12:55 – research showing that insulin resistance is driven by poor glucose metabolism

20:50 – impaired glucose uptake is not caused by excess insulin; fat-burning and impaired glucose metabolism are the culprits 

27:10 – the problems with relying on fat oxidation over carbohydrate oxidation 

30:43 – how increasing blood glucose levels or increasing insulin can restore normal glucose uptake in diabetes

35:28 – how insulin actually lowers blood sugar and the effects of insulin on cortisol and other stress hormones

37:16 - why fatty acid oxidation is NOT the underlying cause of insulin resistance

40:06 – factors that support or block mitochondrial respiration

41:20 – how excess fatty acid oxidation contributes to the pathology of insulin resistance and can impair glucose metabolism over time

42:49 - how insulin actually lowers blood sugar and the effects of insulin on cortisol and other stress hormones (cont.)

47:08 – why we don’t want to blame insulin for insulin resistance and what really causes high fasting blood glucose

49:22 – how low-carb diets increase stress hormones and decrease insulin sensitivity

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