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Ninja Nerd (Ninja Nerd)

Explore every episode of Ninja Nerd

Dive into the complete episode list for Ninja Nerd. Each episode is cataloged with detailed descriptions, making it easy to find and explore specific topics. Keep track of all episodes from your favorite podcast and never miss a moment of insightful content.

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1–50 of 80

Pub. DateTitleDuration
03 Mar 2022Cardiac Tamponade00:24:51

This week, Rob and Zach will be teaching you everything you need to know about Cardiac Tamponade.

We will be discussing:

  • Definition of Cardiac Tamponade
  • Causes
  • Pathophysiology
  • Clinical Features
  • Physical Exam Findings
  • Diagnosis
  • Treatment

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org

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24 Feb 2022Ninja Nerd Trailer00:01:09

Ninja Nerds!

Join Rob and Zach as they give you a sneak peak of what's to come. Ninja Nerd Podcast premieres March 3rd!

 We will be hosting our podcast on our website: https://ninjanerd.org

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10 Mar 2022Infective Endocarditis00:33:00

This week, Rob and Zach will be teaching you everything you need to know about Infective Endocarditis.

We will be discussing:

  • Definition of Infective Endocarditis
  • Causes
  • Pathophysiology
  • Clinical Features
  • Physical Exam Findings
  • Diagnosis
  • Treatment
  • Prevention

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org

www.ninjanerd.org/podcast/infective-endocarditis

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17 Mar 2022Acid Base Disorders & ABG Interpretation00:26:25

This week, Rob and Zach will be teaching you everything you need to know about Acid Base Disorders & ABG Interpretation

We will be discussing:

  • Definition of Acidosis and Alkalosis
  • Complications
  • Compensation Mechanisms
  • ABG Interpretation

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/acid-base-disorders-abg-interpretation

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24 Mar 2022Respiratory Acidosis00:26:22

This week, Rob and Zach will be continuing our series on Acid Base Disorders and ABG interpretation and will be discussing Respiratory Acidosis.

We will be discussing:

  • Definition of Respiratory Acidosis
  • Causes
  • Clinical Features & Physical Exam Findings
  • ABG Case Examples
  • Diagnosis
  • Treatment

To follow along with Notes & Illustrations for our podcasts please become a member on our website! www.ninjanerd.org/podcast/respiratory-acidosis

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Song: Sub Urban - Cradles [NCS Release]
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Free Download/Stream: http://ncs.io/Cradles
Watch: http://youtu.be/Hn4sfC2PbhI

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31 Mar 2022Respiratory Alkalosis00:20:54

This week, Rob and Zach will be continuing our series on Acid Base Disorders and ABG interpretation and will be discussing Respiratory Alkalosis.

We will be discussing:

  • Definition of Respiratory Alkalosis
  • Causes
  • Clinical Features & Physical Exam Findings
  • ABG Case Examples
  • Diagnosis
  • Treatment

To follow along with Notes & Illustrations for our podcasts please become a member on our website! www.ninjanerd.org/podcast/respiratory-alkalosis
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07 Apr 2022Metabolic Alkalosis00:20:46

This week, Rob and Zach will be continuing our series on Acid Base Disorders and ABG interpretation and will be discussing Metabolic Alkalosis.

We will be discussing:

  • Definition of Metabolic Alkalosis
  • Causes
  • Clinical Features & Physical Exam Findings
  • ABG Case Examples
  • Diagnosis
  • Treatment

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/metabolic-alkalosis

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14 Apr 2022Metabolic Acidosis00:34:34

This week, Rob and Zach will be continuing our series on Acid Base Disorders and ABG interpretation and will be discussing Metabolic Acidosis.

We will be discussing:

  • Definition of Metabolic Acidosis
  • Causes
  • Clinical Features & Physical Exam Findings
  • ABG Case Examples
  • Diagnosis
  • Treatment

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/metabolic-acidosis

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21 Apr 2022Ninja Nerd Presents: Dr. Mike Todorovic01:44:10

This week, Rob and Zach will be welcoming and interviewing our guest, Dr. Mike Todorovic.  Dr. Mike is a Senior Lecturer and Medical Researcher at Griffith University in Australia. For the past five years it has been Dr. Mike's passion and joy to create medical lectures on his YouTube channel: Dr. Matt & Dr. Mike and medical Podcasts on Dr. Matt & Dr. Mike's Medical Podcast

We will be discussing:

  • Our Upcoming Research Study - Medical Education Videos on YouTube: An Analysis of Viewing Patterns during the COVID-19 Pandemic.
    • Our research question is: How has viewership of medical education videos on YouTube changed in response to the COVID-19 pandemic?
    • This research study will aim to analyze pre-pandemic and post-pandemic viewership analytics from both of our YouTube channels
    • Our goal is to show how important online medical education is and the major paradigm shift we are seeing in delivering online education across the globe
  • How Can YouTube medical educators remain accurate and credible- Dr. Mike and Zach weigh in on how they aim for complete accuracy when creating lectures
  • How does Zach prepare for a topic and how is this comparable to the way Dr. Mike prepares for a topic
  • How was Ninja Nerd formed?
  • How was Dr. Matt & Dr. Mike formed?
  • Australian and Hawaiian Slang: Dr. Mike and Zach define some slang terminology

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/ninja-nerd-presents-dr-mike-todorovic

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28 Apr 2022Shock00:36:09

This week, Rob and Zach will be teaching you everything you need to know about Shock. This will include the following subcategories of shock:

  • Hypovolemic
  • Cardiogenic
  • Obstructive
  • Distributive
    • Septic
    • Anaphylactic
    • Neurogenic

We will be discussing the following topics within this episode on shock!

  • Definition of Shock
  • Causes / Pathophysiology
  • Clinical Features
  • Physical Exam Findings: Hemodynamic Parameters
  • Diagnosis
  • Treatment

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/shock

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05 May 2022Atrial Fibrillation00:27:48

This week, Rob and Zach will be teaching you everything you need to know about Atrial Fibrillation.

We will be discussing the following topics within this episode on atrial fibrillation!

  • Definition of AFib
  • Causes / Pathophysiology
  • Clinical Features
  • Physical Exam Findings
  • Diagnosis
  • Treatment

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/atrial-fibrillation

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12 May 2022Aortic Dissection00:20:28

This week, Rob and Zach will be teaching you everything you need to know about Aortic Dissection.

We will be discussing the following topics within this episode on aortic dissection!

  • Definition of Aortic Dissection
  • Causes / Pathophysiology
  • Clinical Features
  • Physical Exam Findings
  • Diagnosis
  • Treatment

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/aortic-dissection

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19 May 2022Stroke01:22:27

This week, Rob and Zach will be teaching you everything you need to know about Strokes. This will be a special episode to raise awareness for strokes during the month of May, which is #StrokeMonth

During this episode we are going to be using our medical notes on acute ischemic stroke to discuss this topic and help you master this difficult disease. We highly recommend you follow along with us! Acute Ischemic Stroke Notes

This episode will be talking about ischemic strokes and we will cover hemorrhagic strokes in another episode. During this episode we will be going over the following categories in detail:

  • Definition of Ischemic Stroke
  • Causes / Pathophysiology
  • Stroke Syndromes & Clinical Features
  • Diagnosis
  • Treatment
  • Complications

YouTube Videos to watch on this subject:
Acute Ischemic Stroke
Stroke Syndromes
Ischemic and Hemorrhagic Strokes | High Yield
Case Study #2 Acute Ischemic Stroke

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/stroke

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26 May 2022Vasopressors00:50:46

This week, Rob and Zach will be teaching you everything you need to know about Vasopressors!

We will be discussing the mechanism of action, indications, titration parameters, pros/cons, and routes of administration during this episode on Vasopressors! 

The categories of Vasopressors we will be discussing will include:

  • Inodilators
  • Inopressors
  • Pure Vasopressors
  • Other Vasopressors
  • Oral Vasopressor

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/vasopressors

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02 Jun 2022Pulmonary Embolism00:45:40

This week, Rob and Zach will be teaching you everything you need to know about Pulmonary Emboli.

We will be discussing the following topics within this episode on Pulmonary Embolism!

  • Definition of Pulmonary Embolism
  • Causes / Pathophysiology
  • Clinical Features
  • Physical Exam Findings
  • Diagnosis
  • Treatment

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/pulmonary-embolism

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09 Jun 2022Pneumothorax00:27:57

This week, Rob and Zach will be teaching you everything you need to know about a Pneumothorax.

We will be discussing the following topics within this episode on Pneumothorax!

  • Definition of Pneumothorax
  • Lung Anatomy
  • Causes / Pathophysiology
  • Clinical Features
  • Physical Exam Findings
  • Diagnosis
  • Treatment

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/pneumothorax

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16 Jun 2022Acute Respiratory Distress Syndrome | ARDS00:44:16

This week, Rob and Zach will be teaching you everything you need to know about Acute Respiratory Distress Syndrome (ARDS).

We will be discussing the following topics within this episode on ARDS!

  • Definition of ARDS
  • Causes / Pathophysiology
  • Clinical Features
  • Physical Exam Findings
  • Diagnosis
  • Treatment

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org

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23 Jun 2022Chronic Kidney Disease | CKD00:20:58

This week, Rob and Zach will be teaching you everything you need to know about Chronic Kidney Disease (CKD).

We will be discussing the following topics within this episode on CKD!

  • Definition of CKD
  • Causes / Pathophysiology
  • Clinical Features
  • Physical Exam Findings
  • Diagnosis
  • Treatment

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/chronic-kidney-disease-ckd

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30 Jun 2022Hyperkalemia00:20:10

This week, Rob and Zach will be teaching you everything you need to know about Hyperkalemia.

We will be discussing the following topics within this episode on Hyperkalemia!

  • Definition of Hyperkalemia
  • Causes / Pathophysiology
  • Clinical Features
  • Physical Exam Findings
  • Diagnosis
  • Treatment

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/hyperkalemia

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07 Jul 2022Acute Pancreatitis00:19:15

This week, Rob and Zach will be teaching you everything you need to know about Acute Pancreatitis.

We will be discussing the following topics within this episode on Acute Pancreatitis!

  • Definition of Acute Pancreatitis
  • Causes / Pathophysiology
  • Clinical Features
  • Physical Exam Findings
  • Diagnosis
  • Treatment

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/acute-pancreatitis

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14 Jul 2022GI Bleed00:27:36

This week, Rob and Zach will be teaching you everything you need to know about a GI Bleed.

We will be discussing the following topics within this episode on GI Bleed!

  • Definition of GI Bleed
  • Causes / Pathophysiology
  • Clinical Features
  • Physical Exam Findings
  • Diagnosis
  • Treatment

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/gi-bleed

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21 Jul 2022Inflammatory Bowel Disease (IBD): Crohn's Disease & Ulcerative Colitis00:21:05

This week, Rob and Zach will be teaching you everything you need to know about Inflammatory Bowel Disease (IBD): Crohn's Disease & Ulcerative Colitis.

We will be discussing the following topics within this episode on IBD!

  • Introduction to Crohn's & Ulcerative Colitis
  • Causes / Pathophysiology
  • Clinical Features
  • Physical Exam Findings
  • Diagnosis
  • Treatment

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org

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28 Jul 2022Hypoparathyroidism00:16:27

This week, Rob and Zach will be teaching you everything you need to know about Hypoparathyroidism.

We will be discussing the following topics within this episode on Hypoparathyroidism!

  • Introduction to Hypoparathyroidism
  • Causes / Pathophysiology
  • Clinical Features
  • Physical Exam Findings
  • Diagnosis
  • Treatment

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/hypoparathyroidism

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04 Aug 2022Hyperparathyroidism00:32:44

This week, Rob and Zach will be teaching you everything you need to know about Hyperparathyroidism.

We will be discussing the following topics within this episode on Hyperparathyroidism!

  • Introduction to Hyperparathyroidism
  • Causes / Pathophysiology
  • Clinical Features
  • Physical Exam Findings
  • Diagnosis
  • Treatment

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/hyperparathyroidism

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11 Aug 2022Acute Kidney Injury (AKI)00:47:41

This week, Rob and Zach will be teaching you everything you need to know about Acute Kidney Injury (AKI).

We will be discussing the following topics within this episode on AKI!

  • Definition of AKI
  • Causes / Pathophysiology
  • Clinical Features
  • Physical Exam Findings
  • Diagnosis
  • Treatment

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/acute-kidney-injury-aki

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18 Aug 2022Multiple Sclerosis (MS)00:35:46

This week, Rob and Zach will be talking about Multiple Sclerosis (MS).

We will be discussing the following topics within this episode on MS!

  • Introduction / Types of Multiple Sclerosis
  • Causes / Pathophysiology
  • Clinical Features
  • Physical Exam Findings
  • Diagnosis
  • Treatment

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/multiple-sclerosis-ms

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25 Aug 2022Types of Headaches00:46:00

This week, Rob and Zach will be talking about Types of Headaches including Primary and Secondary Headaches. 

We will be discussing the following topics within this episode on Types of Headaches!

  • Introduction to Types of Headaches
  • Definition, Causes, Pathophysiology, Clinical Features, Diagnosis, Treatment of Secondary Headaches:
    • Mass Occupying Lesions
    • Non-Mass Occupying Lesions
    • Pathology Outside of the CNS
  • Definition, Causes, Pathophysiology, Clinical Features, Diagnosis, Treatment of Primary Headaches:
    • Migraines
    • Cluster Headaches
    • Tension Headaches

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/types-of-headaches

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01 Sep 2022COPD00:23:32

This week, Rob and Zach will be talking about Chronic Obstructive Pulmonary Disease (COPD).

We will be discussing the following topics within this episode on COPD!

  • Introduction to COPD
  • Causes / Pathophysiology
  • Clinical Features
  • Physical Exam Findings
  • Diagnosis
  • Treatment

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/copd

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08 Sep 2022Asthma00:26:58

This week, Rob and Zach will be talking about Asthma.

We will be discussing the following topics within this episode on Asthma!

  • Introduction to Asthma
  • Causes / Pathophysiology
  • Clinical Features
  • Physical Exam Findings
  • Diagnosis
  • Treatment

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/asthma

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15 Sep 2022Pneumonia00:45:31

This week, Rob and Zach will be talking about Pneumonia.

We will be discussing the following topics within this episode on Pneumonia!

  • Introduction to Pneumonia
  • Causes / Pathophysiology
  • Clinical Features
  • Physical Exam Findings
  • Diagnosis
  • Treatment

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/pneumonia

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22 Sep 2022Tuberculosis00:27:45
This week, Rob and Zach will be talking about Tuberculosis.

We will be discussing the following topics within this episode on Tuberculosis!

  • Introduction to Tuberculosis
  • Causes / Pathophysiology
  • Clinical Features
  • Physical Exam Findings
  • Diagnosis
  • Treatment

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/tuberculosis

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29 Sep 2022Antihypertensive Drugs00:51:03

This week, Rob and Zach will be talking about Antihypertensive Drugs to supplement our YouTube lecture on Antihypertensive Drugs.

We will be discussing the following topics within this episode on Antihypertensive Drugs!

  • Defining Hypertension
  • Mechanism of Hypertension
  • Mechanisms of Antihypertensive Agents
  • Indications and Adverse Drug Reactions of Antihypertensive Agents
  • Drug Categories of Antihypertensive Agents
    • Centrally Acting
    • Beta Blockers
    • Nondihydropyridine Calcium Channel Blockers
    • Alpha Blockers
    • Alpha + Beta Blockers
    • Dihydropyridine Calcium Channel Blockers
    • Direct Acting
    • RAAS Inhibitors
    • Thiazide Diuretics
    • Loop Diuretics
    • Aldosterone Antagonists

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/antihypertensive-drugs

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06 Oct 2022Antianginal Drugs00:28:31

This week, Rob and Zach will be talking about Antianginal Drugs.

We will be discussing the following topics within this episode on Antianginal Drugs!

  • Defining Angina
  • Pathophysiology of Angina
  • Mechanism of Antianginal Drugs
  • Indications and Adverse Drug Reactions of Antianginal Drugs
  • Drug Categories of Antianginal Agents will include:
    • Beta Blockers
    • Calcium Channel Blockers
    • Nitrates
    • Ranolazine

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/antianginal-drugs

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13 Oct 2022Drugs for Hyperlipidemia00:39:51

This week, Rob and Zach will be talking about Drugs for Treating Hyperlipidemia. Make sure you stick around for the entire episode, this one is a beauty, unlike my coronary vessels...

We will be discussing the following topics within this episode on Hyperlipidemia Drugs!

  • Defining Hyperlipidemia
  • Pathophysiology & Complications of Hyperlipidemia
  • Drug Categories of Hyperlipidemia Drugs:
    • HMG CoA Reductase Inhibitors
    • Niacin
    • Fibrates
    • Bile Acid Sequestrants
    • Cholesterol Absorption Inhibitors
    • PCSK9 Inhibitors
  • ACC/AHA Guidelines for Hyperlipidemia
  • Combination Therapy

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https:// www.ninjanerd.org/podcast/drugs-for-hyperlipidemia

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20 Oct 2022Drugs for Heart Failure01:00:13

This week, Rob and Zach will be talking about Drugs for Treating Heart Failure - Let's master this topic together, Ninja Nerds!

We will be discussing the following topics within this episode on Drugs for Heart Failure!

  • Defining Congestive Heart Failure (CHF)
  • Pathophysiology of CHF
  • Drug Categories used to Treat Heart Failure:
    • Beta Blockers
    • ACE Inhibitors
    • Angiotensin II Receptor Blockers (ARBs)
    • Neprilysin Inhibitors + ARB (Known as ARNi)
    • Hydralazine + Isosorbide Dinitrate
    • Diuretics
    • Ivabradine
    • Positive Inotropes (Digoxin, Dobutamine, Milrinone, Dopamine)
  • NYHA Heart Failure Classification
  • Acute Heart Failure
    • Causes
    • Pathophysiology
    • Complications
    • Treatment

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/drugs-for-heart-failure

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27 Oct 2022Antiarrhythmic Drugs00:52:56

This week, Rob and Zach will be talking about Antiarrhythmic Drugs

We will be discussing the following topics within this episode on Antiarrhythmic Drugs!

  • Defining an Arrhythmia
  • Pathophysiology of an Arrhythmia:
    • Abnormal Automaticity
    • Increased Triggered Activity
    • Re-Entrant Circuits
  • Antiarrhythmic Drug Categories:
    • Class I: Sodium Channel Blockers (Type Ia, Ib, Ic)
    • Class II: Beta Blockers
    • Class III: Potassium Channel Blockers
    • Class IV: Calcium Channel Blockers
    • Class V: Miscellaneous
      • Adenosine
      • Magnesium
      • Digoxin

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https:// www.ninjanerd.org/podcast/antiarrhythmic-drugs 

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03 Nov 2022Diuretics00:35:15

This week, Rob and Zach will be talking about Diuretics

We will be discussing the following topics within this episode on Diuretics!

  • Defining a Diuretic
  • Diuretics Drug Categories:
    • Osmotic Diuretics
    • Carbonic Anhydrase Inhibitors
    • Loop Diuretics
    • Thiazide Diuretics
    • Potassium Sparing Diuretics
  • Diuretics MOA
  • Therapeutic Indications
  • Adverse Drug Reactions (ADR's)

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/diuretics

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10 Nov 2022Anticoagulants, Thrombolytics, and Antiplatelet Agents01:13:37

This week, Rob and Zach will be talking about Anticoagulants, Thrombolytics, and Antiplatelet Agents

We will be discussing the following topics within this episode on Anticoagulants, Thrombolytics, and Antiplatelet Agents!

  • Hemostasis: Coagulation Cascade, Extrinsic + Intrinsic Pathway
  • Anticoagulants:
    • Heparin
      • UFH
      • LMWH
      • Fondaparinux 
    • Direct Factor Inhibitors
      • Xa Inhibitors:
        • Rivaroxaban
        • Apixaban
        • Edoxaban
      • Thrombin Inhibitors:
        • Dabigatran
        • Argatroban
        • Bivalirudin
    • Vitamin K Antagonists:
      • Warfarin (Coumadin)
  • Thrombolytics (tPA):
    • Alteplase
    • Reteplase
    • Tenecteplase
    • Streptokinase
    • Urokinase
  • Antiplatelets:
    • Aspirin
    • P2y12 Receptor Blockers:
      • Clopidogrel
      • Ticagrelor
      • Prasugrel
      • Ticlopidine
    • GP2b/3a Inhibitors:
      • Abciximab
      • Eptifibatide
      • Tirofiban
    • PDE-3 Inhibitors:
      • Cilostazol
  • Anticoagulants, Thrombolytics, Antiplatelet Agents MOA
  • Therapeutic Indications
  • Adverse Drug Reactions (ADR's)
  • Drug Complications

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/anticoagulants-thrombolytics-and-antiplatelet-agents

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17 Nov 2022Autonomic Pharmacology: Adrenergic Agonists01:11:14

This week, Rob and Zach will be talking about Adrenergic Agonists within our short four part series on Autonomic Pharmacology

We will be discussing the following topics within this episode on Adrenergic Agonists!

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/autonomic-pharmacology-adrenergic-agonists

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24 Nov 2022Autonomic Pharmacology: Adrenergic Antagonists00:42:18

This week, Rob and Zach will be talking about Adrenergic Antagonists within our short four part series on Autonomic Pharmacology

We will be discussing the following topics within this episode on Adrenergic Antagonists!

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org

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01 Dec 2022Autonomic Pharmacology: Cholinergic Agonists00:36:11

This week, Rob and Zach will be talking about Cholinergic Agonists within our short four part series on Autonomic Pharmacology

We will be discussing the following topics within this episode on Cholinergic Agonists!

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/autonomic-pharmacology-cholinergic-agonists

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29 Dec 2022Parkinson's Disease Drugs00:38:02

This week, Rob and Zach will be talking about Parkinson's Disease (PD) Drugs

We will be discussing the following topics within this episode on Parkinson's Disease (PD) Drugs!

  • Anatomy of Basal Ganglia
    • Direct vs. Indirect Pathway
  • Pathophysiology and Mechanism of Action of PD Drugs
  • PD Drug Categories
    • L-dopa & Carbidopa
    • Dopamine Agonists
    • COMT-Inhibitors
    • MAO-B-Inhibitors
    • Amantadine
    • Anticholinergics
  • Complications
  • Adverse Drug Effects

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/parkinsons-disease-drugs

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08 Dec 2022Autonomic Pharmacology: Muscarinic Antagonists00:24:05

This week, Rob and Zach will be talking about Muscarinic Antagonists within our short four part series on Autonomic Pharmacology

We will be discussing the following topics within this episode on Muscarinic Antagonists!

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/autonomic-pharmacology-muscarinic-antagonists

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15 Dec 2022Hyponatremia01:19:21

This week, Rob and Zach will be talking about Hyponatremia.

We will be discussing the following topics within this episode on Hyponatremia!

  • Introduction to Hyponatremia
  • Causes / Pathophysiology
  • Clinical Features
  • Physical Exam Findings
  • Diagnosis
  • Treatment

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/hyponatremia

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22 Dec 2022Hypernatremia00:26:11

This week, Rob and Zach will be talking about Hypernatremia.

We will be discussing the following topics within this episode on Hypernatremia!

  • Introduction to Hypernatremia
  • Causes / Pathophysiology
  • Clinical Features
  • Physical Exam Findings
  • Diagnosis
  • Treatment

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/hypernatremia

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05 Jan 2023Drugs for Epilepsy00:27:29

This week, Rob and Zach will be talking about Drugs for Epilepsy.

We will be discussing the following topics within this episode on Drugs for Epilepsy!

  • Classification between Seizures & Epilepsy
  • Causes / Pathophysiology
  • Mechanism of Anti Epileptic Drugs (AEDs)
  • Clinical Approach to Epilepsy
  • Adverse Drug Reactions & Systematic Involvement

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/drugs-for-epilepsy

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12 Jan 2023Anxiolytic & Hypnotic Drugs00:43:39

This week, Rob and Zach will be talking about Anxiolytic & Hypnotic Drugs.

We will be discussing the following topics within this episode on Anxiolytic & Hypnotic Drugs!

  • Pathophysiology
    • Anxiety
    • Insomnia
  • Mechanism of Action
    • Anxiolytics
    • Hypnotics
  • Treatment Approach
    • Anxiety
    • Insomnia
  • Adverse Drug Reactions
    • Anxiolytics
    • Hypnotics

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/anxiolytic-hypnotic-drugs

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19 Jan 2023Cushing's Syndrome00:27:58

This week, Rob and Zach will be talking about Cushing's Syndrome.

We will be discussing the following topics within this episode on Cushing's Syndrome!

  • The Cortisol Pathway and Normal Physiology
  • Cortisol Target Organs & Effects
  • Causes of High Cortisol
  • Diagnostic Workup
  • Treatment

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/cushings-syndrome

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26 Jan 2023Hyperaldosteronism00:26:47

This week, Rob and Zach will be talking about Hyperaldosteronism.

We will be discussing the following topics within this episode on Hyperaldosteronism!

  • The Aldosterone Pathway and Normal Physiology
  • Aldosterone Target Organs & Effects
  • Causes of High Aldosterone
  • Diagnostic Workup
  • Treatment

To follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.org/podcast/hyperaldosteronism

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14 May 2024Volume Disorders00:33:29

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Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we explore the intricacies of hypovolemia and hypervolemia. You'll learn about the causes, symptoms, and treatment options for both conditions. We'll discuss clinical cases to highlight key diagnostic and management strategies, ensuring you're well-prepared for your exams and clinical practice. Whether you're a medical student, resident, or practicing clinician, this episode offers valuable insights to enhance your understanding of volume disorders.

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12 Jul 2024Acid-Base Disorders00:53:23

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Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we discuss Acid-Base Disorders. You'll learn about the causes, symptoms, and treatment options for Metabolic Acidosis, Metabolic Alkalosis, Respiratory Acidosis, and Respiratory Alkalosis. We'll discuss clinical cases to highlight critical diagnostic and management strategies, ensuring you're well-prepared for your exams and clinical practice. Whether you're a medical student, resident, or practicing clinician, this episode offers valuable insights to enhance your understanding of Acid-Base Disorders. Please support us below!

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19 Jul 2024Sodium Disorders00:33:46

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Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we discuss Sodium Disorders. You'll learn about the causes, symptoms, and treatment options for Hyponatremia and Hypernatremia. We'll discuss clinical cases to highlight critical diagnostic and management strategies, ensuring you're well-prepared for your exams and clinical practice. Whether you're a medical student, resident, or practicing clinician, this episode offers valuable insights to enhance your understanding of Sodium Disorders. Please support us below!

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26 Jul 2024Potassium Disorders00:32:42

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Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we discuss Potassium Disorders. You'll learn about the causes, symptoms, and treatment options for Hypokalemia and Hyperkalemia. We'll discuss clinical cases to highlight critical diagnostic and management strategies, ensuring you're well-prepared for your exams and clinical practice. Whether you're a medical student, resident, or practicing clinician, this episode offers valuable insights to enhance your understanding of Potassium Disorders. Please support us below!

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25 Oct 2024Vasculitis00:58:24

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Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we discuss Vasculitis. You'll learn about the causes, symptoms, and treatment options for Large, Medium, and Small Vessel Vasculitis. We'll discuss clinical cases to highlight critical diagnostic and management strategies for diseases such as Giant Cell Arteritis, Takayasu's Arteritis, Polyarteritis Nodosa, Kawasaki Disease, Granulomatosis with Polyangiitis (GPA), Eosinophilic Granulomatosis with Polyangiitis (EGPA), Microscopic Polyangiitis (MPA), IgA Vasculitis, and Cryoglobulinemic Vasculitis. Whether you're a medical student, resident, or practicing clinician, this episode offers valuable insights to enhance your understanding of Vasculitis. Please support us below!

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02 Aug 2024Calcium Disorders00:36:42

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Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we discuss Calcium Disorders. You'll learn about the causes, symptoms, and treatment options for Hypocalcemia and Hypercalcemia. We'll discuss clinical cases to highlight critical diagnostic and management strategies, ensuring you're well-prepared for your exams and clinical practice. Whether you're a medical student, resident, or practicing clinician, this episode offers valuable insights to enhance your understanding of Calcium Disorders. Please support us below!

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09 Aug 2024Acute Kidney Injury (AKI)00:48:31

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Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we discuss Acute Kidney Injury (AKI). You'll learn about the causes, symptoms, and treatment options for Prerenal, Intrarenal, and Postrenal AKI. We'll discuss three clinical cases to highlight critical diagnostic and management strategies, ensuring you're well-prepared for your exams and clinical practice. Whether you're a medical student, resident, or practicing clinician, this episode offers valuable insights to enhance your understanding of Acute Kidney Injury (AKI). Please support us below!

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16 Aug 2024Chronic Kidney Disease (CKD)00:42:52

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Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we discuss Chronic Kidney Disease (CKD). You'll learn about the causes, symptoms, and treatment options for CKD. We'll discuss clinical cases to highlight critical diagnostic and management strategies, ensuring you're well-prepared for your exams and clinical practice. Whether you're a medical student, resident, or practicing clinician, this episode offers valuable insights to enhance your understanding of Chronic Kidney Disease (CKD). Please support us below!

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23 Aug 2024Glomerular Diseases00:41:43

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Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we discuss Glomerular Diseases, including Nephrotic and Nephritic Syndrome. You'll learn about the causes, symptoms, and treatment options for Glomerular Diseases. We'll discuss clinical cases to highlight critical diagnostic and management strategies, ensuring you're well-prepared for your exams and clinical practice. Whether you're a medical student, resident, or practicing clinician, this episode offers valuable insights to enhance your understanding of Glomerular Diseases. Please support us below!

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20 Sep 2024Cystic Kidney Disease00:19:51

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Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we discuss Cystic Kidney Disease. You'll learn about the causes, symptoms, and treatment options for Cystic Kidney Disease. We'll discuss clinical cases to highlight critical diagnostic and management strategies, ensuring you're well-prepared for your exams and clinical practice. Whether you're a medical student, resident, or practicing clinician, this episode offers valuable insights to enhance your understanding of Cystic Kidney Disease. Please support us below!

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27 Sep 2024Approach to Hematuria00:19:34

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Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we discuss the Approach to Hematuria. You'll learn about the causes, symptoms, and treatment options for Hematuria. We'll discuss clinical cases to highlight critical diagnostic and management strategies, ensuring you're well-prepared for your exams and clinical practice. Whether you're a medical student, resident, or practicing clinician, this episode offers valuable insights to enhance your understanding of Hematuria. Please support us below!

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04 Oct 2024IV Fluids00:21:05

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Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we discuss IV Fluids. You'll learn about the causes, symptoms, and treatment options for IV Fluids. We'll discuss clinical cases to highlight critical diagnostic and management strategies, ensuring you're well-prepared for your exams and clinical practice. Whether you're a medical student, resident, or practicing clinician, this episode offers valuable insights to enhance your understanding of IV Fluids. Please support us below!

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11 Oct 2024Diuretics00:22:34

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Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we discuss Diuretics. You'll learn about the causes, symptoms, and treatment options for Diuretics. We'll discuss clinical cases to highlight critical diagnostic and management strategies, ensuring you're well-prepared for your exams and clinical practice. Whether you're a medical student, resident, or practicing clinician, this episode offers valuable insights to enhance your understanding of Diuretics. Please support us below!

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18 Oct 2024Nephrolithiasis00:35:11

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Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we discuss Nephrolithiasis. You'll learn about the causes, symptoms, and treatment options for Nephrolithiasis. We'll discuss clinical cases to highlight critical diagnostic and management strategies, ensuring you're well-prepared for your exams and clinical practice. Whether you're a medical student, resident, or practicing clinician, this episode offers valuable insights to enhance your understanding of Nephrolithiasis. Please support us below!

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02 Nov 2024Microcytic Anemia00:42:19

Ninja Nerds!
Welcome to the Ninja Nerd Podcast with Zach and Rob! This episode is on Microcytic Anemia, covering the major types such as iron deficiency anemia, thalassemia, anemia of chronic disease, and sideroblastic anemia. Enjoy the podcast and support us below!

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08 Nov 2024Normocytic Anemia01:15:58

Ninja Nerds!
Welcome to the Ninja Nerd Podcast with Zach and Rob! This episode dives into Normocytic Anemia, exploring the primary types, including Aplastic Anemia, Paroxysmal Nocturnal Hemoglobinuria (PNH), G6PDH Deficiency, Hereditary Spherocytosis, Autoimmune Hemolytic Anemia (AIHA), Sickle Cell Anemia, Microangiopathic Hemolytic Anemia (MAHA), Acute Blood Loss Anemia (ABLA). Enjoy the podcast, and be sure to support us below!

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15 Nov 2024Macrocytic Anemia00:31:44

Ninja Nerds!
Welcome to the Ninja Nerd Podcast with Zach and Rob! This episode dives into Macrocytic Anemia. During this discussion, we will review B12 Deficiency Anemia, Folate Deficiency Anemia, and Non-Megaloblastic Anemia. We have three cases we will be working through, so please listen along and see if you can figure out these cases.  Enjoy the podcast, and be sure to support us below!

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22 Nov 2024Blood Transfusions01:00:31

Ninja Nerds!
Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we dive into blood transfusions, breaking down the essential components and clinical uses. We will discuss packed red blood cell transfusions (PRBC) for anemia management, platelet transfusions for thrombocytopenia and bleeding risk, and the role of Fresh Frozen Plasma (FFP) transfusions in reversing anticoagulation or treating coagulopathies. You will also learn about Prothrombin Complex Concentrate (PCC) transfusions for rapid anticoagulant reversal, Cryoprecipitate Transfusions for fibrinogen replacement, and how to manage complications like transfusion-related acute lung injury (TRALI). Lastly, we will tackle the massive transfusion protocol (MTP), also known as a Code Crimson, highlighting its life-saving importance in critical care settings. Enjoy the podcast, and please support us below!

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29 Nov 2024Platelet Disorders00:58:22

Ninja Nerds!

Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we explore Platelet Disorders, breaking down the essential concepts and clinical applications. We will discuss Heparin-Induced Thrombocytopenia (HIT), focusing on its pathophysiology and management. Learn about Antiphospholipid Syndrome (APLS) and its role in thrombosis and pregnancy complications. We’ll also cover Disseminated Intravascular Coagulation (DIC), including its triggers and treatment strategies, and Hemolytic Uremic Syndrome (HUS), with an emphasis on its pediatric presentations. Dive into Thrombotic Thrombocytopenic Purpura (TTP) and its life-threatening manifestations, Von Willebrand Disease (vWD) as the most common inherited bleeding disorder, and Immune Thrombocytopenic Purpura (ITP), highlighting its diagnostic approach and treatment. Enjoy the podcast, and please support us below!

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17 Jan 2025Coagulopathy00:39:33

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Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we explore Coagulopathy, focusing on key bleeding and clotting disorders. Topics include Hemophilia A and B, their genetic causes, and modern treatments; Von Willebrand Disease (vWD), the most common inherited bleeding disorder; and Heparin-Induced Coagulopathy, with its paradoxical effects. We also cover Acquired Factor VIII Inhibitors in autoimmune and malignancy settings, Vitamin K Deficiency as a cause of bleeding, Disseminated Intravascular Coagulation (DIC) and its management challenges, and coagulopathy in Cirrhosis, linking liver dysfunction to bleeding and thrombosis. Enjoy the episode, and support us below!

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24 Jan 2025Hypercoagulable States00:39:33

Ninja Nerds!

Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we discuss Hypercoagulable States, covering key disorders and their clinical significance. Topics include Antiphospholipid Syndrome (APLS), its role in thrombosis and pregnancy loss; Factor V Leiden Mutation, the most common inherited thrombophilia; and Prothrombin Gene Mutation and its increased clotting risk. We also explore Protein C and S Deficiency, Antithrombin Deficiency, and acquired states like Cancer-Associated Thrombosis, Heparin-Induced Thrombocytopenia (HIT), and Paroxysmal Nocturnal Hemoglobinuria (PNH). Tune in to learn more, and support us below!

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31 Jan 2025Antiplatelets, Anticoagulants, and Thrombolytics00:47:19

Ninja Nerds!
Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we explore Antiplatelets, Anticoagulants, and Thrombolytics, focusing on their mechanisms and clinical uses. Topics include the pharmacology of antiplatelet agents such as aspirin and P2Y12 inhibitors, the role of anticoagulants like heparins, direct oral anticoagulants (DOACs), and warfarin in preventing thromboembolic events, and the use of thrombolytics like tPA in acute ischemic stroke and myocardial infarction. We also discuss strategies for managing bleeding risks, reversal agents, and clinical considerations for optimizing anticoagulation therapy. Enjoy the episode, and support us below!

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07 Feb 2025Plasma Cell Disorders00:27:25

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Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we take a closer look at Plasma Cell Disorders, focusing on their pathophysiology, clinical features, and management. Topics include the mechanisms behind multiple myeloma, monoclonal gammopathy of undetermined significance (MGUS), and Waldenström macroglobulinemia, as well as the role of paraproteins and their clinical implications. We discuss diagnostic approaches such as serum protein electrophoresis (SPEP), immunofixation, and bone marrow biopsy, along with treatment options like proteasome inhibitors, immunomodulatory drugs, and monoclonal antibodies. We also explore complications like hypercalcemia, renal impairment, anemia, and bone lesions, ensuring a high-yield overview for exams and clinical practice. Enjoy the episode, and support us below!

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14 Feb 2025Myeloproliferative Neoplasia00:37:25

Ninja Nerds!

Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we explore Myeloproliferative Neoplasms, covering their pathophysiology, clinical presentation, and management. We discuss Polycythemia Vera, Essential Thrombocythemia, Chronic Myeloid Leukemia, and Primary Myelofibrosis, focusing on key mutations like JAK2, CALR, and BCR-ABL. Our discussion includes diagnostic tools such as peripheral blood smear, bone marrow biopsy, and laboratory markers like erythropoietin levels, leukocyte alkaline phosphatase, and BCR-ABL testing. We also review treatment options, including tyrosine kinase inhibitors, cytoreductive therapy, and JAK inhibitors, as well as complications like thrombosis, bleeding, and transformation to acute leukemia. This episode provides a high-yield review for exams and clinical practice. Enjoy the episode, and support us below!

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21 Feb 2025Acute Leukemias00:45:29

Ninja Nerds,

Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we dive deep into Acute Leukemias, breaking down their pathophysiology, clinical presentation, and management. We explore the key differences between Acute Myeloid Leukemia (AML) and Acute Lymphoblastic Leukemia (ALL), focusing on the genetic mutations, risk factors, and cellular mechanisms driving these malignancies. Our discussion includes high-yield diagnostic approaches such as peripheral blood smear, bone marrow biopsy, flow cytometry, and cytogenetic analysis. We also cover essential treatment strategies, including induction chemotherapy, targeted therapies, and hematopoietic stem cell transplantation (HSCT), while highlighting critical complications like tumor lysis syndrome and leukostasis. This episode is packed with clinically relevant insights and board exam pearls—tune in and support us below!

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28 Feb 2025Chronic Leukemias00:35:23

Ninja Nerds,

Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we explore Chronic Leukemias, focusing on their pathogenesis, clinical features, and modern treatment strategies. We compare Chronic Myeloid Leukemia (CML) and Chronic Lymphocytic Leukemia (CLL), discussing the role of BCR-ABL in CML and the implications of smudge cells and monoclonal B-cell proliferation in CLL. Our conversation covers key diagnostic tools such as PCR, flow cytometry, and blood smear findings, as well as cutting-edge treatment options like tyrosine kinase inhibitors (TKIs) for CML and targeted monoclonal antibody therapy for CLL. We also discuss disease progression, complications like Richter transformation, and indications for therapy in asymptomatic patients. This high-yield episode is perfect for both exam prep and clinical application—enjoy and support us below!

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07 Mar 2025Lymphoma00:34:14

Ninja Nerds,

Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we dive deep into Lymphoma, breaking down its pathogenesis, clinical presentation, and the latest advancements in treatment. We explore the key differences between Hodgkin and Non-Hodgkin Lymphoma, examining the role of Reed-Sternberg cells, CD markers, and genetic mutations that define these malignancies.

Our discussion includes high-yield diagnostic tools like lymph node biopsy, flow cytometry, PET/CT imaging, and molecular studies, helping you differentiate between indolent and aggressive subtypes. We also analyze cutting-edge treatments, including immunotherapy, targeted monoclonal antibodies (e.g., rituximab), chemotherapy regimens like R-CHOP, and the role of stem cell transplantation in refractory cases.

Additionally, we cover disease progression, prognostic factors, and complications such as tumor lysis syndrome and secondary malignancies. Whether you’re studying for boards, preparing for clinical rotations, or just love hematology-oncology, this episode is packed with high-yield pearls you don’t want to miss!

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14 Mar 2025Amyloidosis00:30:35

Ninja Nerds,

Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we explore Amyloidosis, a complex disorder characterized by the misfolding and deposition of insoluble amyloid fibrils in tissues. We break down the different subtypes, including AL (light chain), AA (secondary), ATTR (transthyretin), and Aβ2M (β2 microglobulin), highlighting their unique pathogenesis, clinical manifestations, and diagnostic approaches.

Our discussion covers the systemic vs. localized forms of the disease, exploring how amyloid deposition can impact critical organs like the heart (restrictive cardiomyopathy), kidneys (nephrotic syndrome), nervous system (autonomic and peripheral neuropathy), and gastrointestinal tract. We also walk through essential diagnostic tools, including serum and urine electrophoresis, fat pad biopsy with Congo red staining, mass spectrometry, and advanced imaging techniques like cardiac MRI and PYP scanning for ATTR amyloidosis.

Finally, we break down the latest treatment strategies, from chemotherapy and autologous stem cell transplant for AL amyloidosis. Whether you’re preparing for exams, rotations, or just want to master this challenging topic, this episode is packed with high-yield insights to boost your understanding!

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21 Mar 2025Breast Cancer00:44:06

Ninja Nerds,

Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we explore Breast Cancer's pathogenesis, risk factors, and the latest advancements in screening, diagnosis, and treatment. We break down the molecular subtypes of breast cancer, including hormone receptor-positive, HER2-positive, and triple-negative disease, and discuss their clinical implications and targeted therapies.

Our discussion covers essential diagnostic tools, such as mammography, breast ultrasound, MRI, and core needle biopsy, emphasizing how to interpret imaging findings and pathology reports. We also analyze prognostic factors, including TNM staging, to guide medical therapies.

Additionally, we explore cutting-edge treatment strategies, including endocrine therapy, HER2-targeted monoclonal antibodies (e.g., trastuzumab), chemotherapy regimens, and advancements in immunotherapy for triple-negative disease. We also discuss surgical options, radiation therapy, and complications such as lymphedema and cardiotoxicity from trastuzumab.

Whether you’re studying for boards, preparing for clinical rotations, or just passionate about oncology, this episode is packed with high-yield pearls you don’t want to miss!

Join the Millionaires in Medicine Club!

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28 Mar 2025Myelodysplastic Syndrome (MDS)00:26:35

Ninja Nerds,
Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we explore Myelodysplastic Syndrome (MDS), a group of hematologic disorders characterized by ineffective hematopoiesis and a risk of progression to acute myeloid leukemia (AML). We also discuss the pathophysiology of MDS, highlighting the clonal stem cell mutations that lead to dysplastic bone marrow changes and peripheral blood cytopenias.

Our discussion explores the clinical presentation of MDS, from common findings like fatigue, pallor, and bleeding tendencies to more concerning signs such as transfusion dependence and infection risk. We also cover the diagnostic approach, emphasizing the importance of bone marrow biopsy findings such as dysplastic cell morphology, ring sideroblasts, and blast percentages. Key scoring systems like the Revised International Prognostic Scoring System (IPSS-R) are discussed to guide risk stratification and treatment decisions.

In this episode, we break down treatment strategies for both low-risk and high-risk MDS, including supportive care with transfusions and growth factors, the role of hypomethylating agents like azacitidine and decitabine, and advanced interventions such as allogeneic stem cell transplantation.

Whether you’re preparing for exams, clinical rotations, or looking to expand your knowledge of hematology, this episode is packed with high-yield insights to help you understand this challenging topic.

Enjoy the episode and support us below! 🔬🩸

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04 Apr 2025Lung Cancer00:46:06

Ninja Nerds,
Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we discuss Lung Cancer, a leading cause of cancer-related mortality worldwide. We explore the pathophysiology, risk factors, and key differences between non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) to help you master this complex topic.

Our discussion covers the clinical presentation of lung cancer, including subtle early symptoms like cough, hemoptysis, and chest pain, as well as advanced findings such as pleural effusions, superior vena cava syndrome, and paraneoplastic syndromes.

Finally, we break down treatment strategies based on staging and tumor type, covering surgical interventions, chemotherapy regimens, immunotherapy, and targeted therapies such as EGFR and ALK inhibitors. We also review the latest advancements in precision medicine and the evolving role of molecular markers in guiding therapy.

Whether you’re preparing for exams or rotations or seeking a deeper understanding of lung cancer, this episode is packed with high-yield insights to boost your clinical knowledge and critical thinking.

Enjoy the episode and support us below! 🌬️🫁

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