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Explore every episode of I AM BIO

Dive into the complete episode list for I AM BIO. Each episode is cataloged with detailed descriptions, making it easy to find and explore specific topics. Keep track of all episodes from your favorite podcast and never miss a moment of insightful content.

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Pub. DateTitleDuration
28 Sep 2021How Drug Price Controls End Up Hurting Patients00:32:26

They are not the household names, but the medications they are researching and developing could be the lifeline patients are waiting for. Today we explore how drug price controls—now making their way through Congress—could have unintended consequences for the small biotechs that are the engine of the drug development ecosystem. And even worse, for the patients who need them most.  

 

Guests:

Ahmed Mousa, Pieris Pharmaceuticals  

Daphne Zohar, PureTech Health

Peter Kolchinsky, RA Capital

Michele Oshman, BIO

Clare Thorpe, Library Services (AU)

17 May 2022Drug Prices: A Dysfunctional Market Limits Patient Access00:25:55

A convoluted, confusing, and opaque system for pricing drugs has evolved that distorts the market and often limits patient access to the drugs they need to survive. In this episode, three experts explain how the system works—or doesn’t’—and the consequences of a dysfunctional pricing system.

Guests:

  • Dan Durham, Senior Health Policy Advisor, Biotechnology Innovation Organization
  • Anna Hyde, Vice President, Advocacy and Access, Arthritis Foundation
  • Dr. Vinay Rathi, Resident Physician, Otolaryngology, Massachusetts Eye and Ear and Mass General Brigham
26 Mar 2024Biotech for our Pets00:28:21

More than half of U.S. households include pets, but there has been a lack of medical treatments developed specifically for small animals. Biotech companies are working to change that with new treatment options that both borrow from and, potentially, advance human health discoveries.

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16 Aug 2021BONUS: Breaking Barriers in Science featuring Dr. Jennifer Doudna, Nobel Laureate and CRISPR Pioneer00:38:25

We are on summer break as we work to bring you another exciting season this fall. So, for the next few weeks we’re sharing some of our favorite sessions from the June 2021 BIO Digital. Today, check out our session Breaking Barriers in Science featuring Dr. Jennifer Doudna, Nobel Laureate and CRISPR Pioneer. This session is sponsored by Johnson & Johnson.  

Speakers:

Seema Kumar, Vice President of Innovation, Global Health and Policy Communication

Dr. Jennifer Doudna, Nobel Laureate and CRISPR Pioneer

23 May 2023Why are Katie Couric and 15K People Headed to Boston?00:16:09

During the last several decades Boston has become a biotech Mecca, with its Kendall Square attracting more than 120 biotech companies, both large and small. It is called the most innovative square mile on the planet.  This June BIO will bring over 15,000 biotech leaders to Boston for its 2023 BIO International Convention. Speakers including award-winning journalist and health advocate, Katie Couric, will talk about how they will “Stand up for Science”—the Convention’s theme. MassBIO CEO, Kendalle Burlin O’Connell joins host, Rachel King in a wide-ranging discussion about how Boston became the largest biotech hub in the world.

30 Nov 2020At Last, COVID Treatments00:31:40
Covid threatens those whose immune systems can’t make enough neutralizing antibodies to fight off the viral invaders. But what if scientists could make super-potent antibodies in the lab and infuse them into newly infected patients? That’s exactly what the first FDA-authorized coronavirus antibody treatment has achieved. Its maker, Eli Lilly, has generated clinical evidence that their therapy can significantly reduce COVID hospitalization rates when taken early.
22 Oct 2024How Love Combined with Science Leads to Hope for Rare Disease00:27:05

There are over 7000 rare diseases identified in the U.S. alone. Many of these diseases affect children, leaving families desperate for answers. In this episode, we talk with one of those families and the biotech company offering them new hope. We also talk with an expert on policy that has jump-started R&D for rare diseases.

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27 Feb 2024Is CRISPR the New Sickle Cell Savior?00:24:39

2023 ended with an exciting biotech breakthrough for sickle cell patients. A gene-editing therapy using the revolutionary CRISPR technology provides new hope and options for the nearly 100,000 Americans with sickle cell disease. In this episode, we talk with the company behind one of the life-changing therapies, CASGEVY, and speak with two advocates for sickle cell patients. 

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Visit us at https://www.bio.org/

23 Apr 2020COVID-19’s True Origins00:38:34
There's a joke among ecological health scientists that if “you don’t believe one person can change the world, try eating an undercooked bat.” However, what EcoHealth Alliance’s Dr. William Karesh — a world-renowned expert on zoonotic disease transmission — reveals about the trend line for animal-to-human viral transmission is no laughing matter. Hosted by Jim Greenwood.
10 Jan 2024How Biotechs Survive the Valley of Death (REDUX)00:25:05

For biotech companies, the valley of death describes the difficult path from initial discovery to FDA approval and commercialization. It's a treacherous journey—one that even promising innovations often don't complete. Adequate funding, regulatory hurdles and the immense complexity of the biotech landscape are among the never-ending challenges faced by early stage biotechs. In this episode we talk with two biotech executives about what it’s like to struggle and survive in this rough-and-tumble industry.  

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08 Jun 2020Vaccine Velocity00:33:17
How can global nonprofits like the Center for Epidemic Preparedness Innovations (CEPI) deliver a safe and effective vaccine against the novel coronavirus in just 12 to 18 months when the world record for vaccine approval is four years? CEPI CEO Richard Hatchett, a 9/11 hero, says it’s all about smart planning. By the time governments give the green light on the safety and efficacy of a covid vaccine, manufacturer capacity will be pre-scaled up and able to quickly churn out doses by the tens or hundreds of millions. Hosted by Jim Greenwood.
07 Sep 2020Sickle Cell Saviors (Redux)01:02:27
Need a dose of inspiration in a time of national tragedy? A remarkable biotech breakthrough from Global Blood Therapeutics offers fresh hope to patients living with sickle-cell disease.
11 Jan 2021COVID X-FACTOR (Redux)00:31:20
The diversity of our adaptive immune system is why people are reacting so differently to the novel coronavirus. No two people present the virus the exact same way to their immune systems. We’ve evolved in this way as humans to ensure no virus can eradicate our species. Hosted by Jim Greenwood.
04 Oct 2022Lessons from Monkeypox: Are We Prepared for the Next Pandemic?00:17:51

Monkeypox hit our shores in May of this year. How did our public health agencies and infrastructure perform? What went right, what went wrong, and what needs to improve? We talked with three experts in public health and biodefense about the threats on their radar screens and how the U.S. can better prepare for the next inevitable outbreak or pandemic.

Guests:

Dr. Asha George, Bipartisan Commission on Biodefense

Dr. Lynn Goldman, Milken Institute School of Public Health at the George Washington University

Dr. John Redd, Medical Countermeasures Coalition 

24 Jul 2024Is CRISPR the New Sickle Cell Savior? (REDUX)00:24:39

2023 ended with an exciting biotech breakthrough for sickle cell patients. A gene-editing therapy using the revolutionary CRISPR technology provides new hope and options for the nearly 100,000 Americans with sickle cell disease. In this episode, we talk with the company behind one of the life-changing therapies, CASGEVY, and speak with two advocates for sickle cell patients. 

15 May 2020Cancer in the COVID Era00:19:34
Overcrowded hospitals during the pandemic can pose treatment challenges for patients with other serious illnesses. As Kite Pharma CEO Christi Shaw says, “Cancer doesn’t stop in a crisis.” Neither do her company’s employees, who go to extraordinary lengths to get personalized CAR-T treatments to patients around the world. Hosted by Jim Greenwood.
30 Apr 2020Destroying COVID's Genome00:38:48
Alnylam Pharmaceuticals, which take its name from the center and brightest star in Orion’s Belt, is working on an RNAi therapy to destroy the genome of the novel coronavirus — and with it, its ability to replicate and kill. Hosted by Jim Greenwood.
23 Jan 2024The Synbio Revolution is Here (REDUX)00:26:14

Innovative companies are using synthetic biology to engineer organisms and create new materials that could transform every sector of our economy, from health care to food and energy production. Those companies say we’ve entered a synbio revolution, and it holds potential to improve the health of people and our planet. In this episode, we talk with three synbio experts about how this convergence of genetic engineering, computer science and other scientific disciplines is making our world more sustainable. 

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03 Aug 2020Clinical Trials and Tribulations00:29:21
As Moderna breaks the record for speed in starting the final stage of human testing for its covid vaccine, new BIO CEO Dr. Michelle McMurry-Heath tackles the thorny issue of how to best structure the historic Phase 3 clinical trial. The Boston biotech’s Chief Medical Officer reveals the strategy to test vaccine efficacy on communities of color and others hardest hit by the coronavirus. Hosted by Dr. Michelle McMurry-Heath
23 Nov 2021Antimicrobial Resistance: The Silent Pandemic00:26:53

We are on the precipice of a looming crisis. Antimicrobial resistance (AMR) is the evolution of deadly pathogens like bacteria and fungi to resist all current antimicrobial medicines. In this episode, we talk about how the dwindling supply of new antibiotics is fueling this silent pandemic, and why we need a continued pipeline of new antibiotics to avoid this crisis.

Guests:

Ankit Mahadevia, Spero Therapeutics

Henry  Skinner, AMR Action Fund

Mary Dwight, Cystic Fibrosis Foundation 

28 Jun 2021Improving Food Systems: The Case of the Banana00:26:29

The banana is an interesting case study. It is the world’s most popular fruit, yet it could very soon go missing from our store shelves due to a disease we’ve seen once before—leaving a large nutritional and economic hole in our society. The banana helps tell the story of how biotech is a key tool in strengthening our food systems to make our favorite foods more resilient, more sustainable, and more accessible. 

Featuring interviews with:

Anna Rath, President & CEO and Director of Vestaron

Dan Koeppel, author of Banana: The Fate of the Fruit that Changed the World

Betsy Booren, SVP of Regulatory and Technical Affairs at the Consumer Brands Association

Tom Vilsack, Secretary of United States Department of Agriculture

31 Jan 2020Superbuggin’00:27:39
Incurable gonorrhea and the deadly hospital superbug C. diff offer a frightening window into the gathering public health menace of antibiotic resistance. If society doesn’t wake up and tackle the problem, we could be headed toward a calamity on the magnitude of climate change. Hosted by Jim Greenwood.
22 Mar 2022Water Stress: Can We Avert a Looming Crisis?00:25:41

More than two-thirds of the Earth’s surface is water, and yet water that is safe enough for human consumption remains a finite resource. In this episode we speak to experts about the biggest threats to water—contamination, overuse, and plastic. We also learn how innovative new tools can ensure there is enough water to hydrate us, our plants, and our animals.  

Guests

14 Nov 2023“On My Own”—Desperate to Stop a Resistant Bacterial Infection00:27:42

Bradley Burnam woke up one morning, looked in the mirror and found one ear twice it’s normal size and his face swollen and discolored. He would spend the next several years in and out of the hospital fighting a relentless infection that would not respond to available treatments. The experience took him from patient to "mad scientist" to biotech company founder. In this episode, Bradley takes us through his desperate journey to find a cure. We also talk with the leader of an organization helping to get more antimicrobials to the marketplace.

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Click HERE to watch the documentary-style film Race Against Resistance presented by the AMR Action Fund and funding support from Pfizer Shionogi and MSD.

17 Aug 2020Respiratory Rescue?00:28:22
The engine powering Maryland vaccine maker Novavax is a recombinant nanoparticle platform that is impressing vaccinologists as well as government and nonprofit funders. Learn about the innovative biotech generating big buzz in the global covid vaccine race.
04 May 2020COVID-19’s True Origins (Redux)00:38:56
There's a joke among ecological health scientists that if “you don’t believe one person can change the world, try eating an undercooked bat.” However, what EcoHealth Alliance’s Dr. William Karesh — a world-renowned expert on zoonotic disease transmission — reveals about the trend line for animal-to-human viral transmission is no laughing matter. Hosted by Jim Greenwood.
07 May 2020“Herd” Immunity00:36:14
Biotech companies are working feverishly to develop antibody therapies to provide short-term protection against COVID-19. But what if the novel coronavirus mutates and outwits traditional monoclonal antibodies? Well, that’s where the super cows come in. Hosted by Jim Greenwood.
26 Apr 2021Solving an Unfashionable Problem00:24:28

The fashion industry is notoriously wasteful. As the climate crisis becomes more of everyone’s problem, scientists and designers are combining efforts to make fashion more sustainable. From using greenhouse gasses to create new materials to developing totally biodegradable clothing and accessories, big fashion houses are trying to produce sustainable materials and make fashion look good and feel great. 

This episode features conversations with:

Jennifer Holmgren, CEO of LanzaTech

Alejandra Espinosa, head of content at Luxiders Magazine

Bridgett Artise, sustainable fashion designer and professor at the Fashion Institute of Technology

Doris de Guzman, biotech journalist

Emilie Burfeind, creator of Sneature and teacher at the University of Art and Design at Offenbach at the Institute for Material Design 

31 Aug 2020COVID-19: We Were Warned (Redux)00:49:35
For years, leaders on the Bipartisan Commission on Biodefense told Congress and the White House that it wasn’t a matter of if, but when, a pandemic would happen. Exploring the panel’s unheeded recommendations can give the United States a blueprint for what to do going forward to protect us from the coronavirus and future threats.
05 Nov 2024The Horseshoe Crab Saved Us. Can We Save the Horseshoe Crab? (REDUX)00:28:02

The horseshoe crab has endured for over 450 million years. It has survived several mass extinctions including the one that killed off the dinosaurs. One reason for their incredible resiliency is their ability to fend off bacterial infection. Their blood contains cells that clot around invading bacteria, thereby protecting them from the attacking toxins.

In this episode we talk with three experts about how this animal’s unique blue blood has become essential to modern medicine. We also talk about why horseshoe crab populations are dwindling, and what biotech is doing to address the shortfall.

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Visit us at https://www.bio.org/

11 Apr 2023The New Age of CRISPR00:27:40

CRISPR has emerged as a powerful tool for altering DNA sequences with incredible precision, opening up new avenues of research into the treatment of disease. In this episode, we explore the science behind CRISPR, as well as its potential. From curing genetic disorders to creating new crop varieties, the possibilities seem endless. Our four guests today are scientists working to push these gene editing tools to the next frontier.

23 Mar 2020Coronavirus Lung Treatment Could be Ready In Weeks00:40:16
Regeneron’s rheumatoid arthritis drug shows promise to treat coronavirus-related lung syndrome and stop the inflammation that leads to death. The company also expects to test a preventative antibody shot in June. Hosted by Jim Greenwood.
06 Aug 2024What We Know About the Microbiome (REDUX)00:27:25

The gut microbiome, which consists of trillions of bacteria, viruses, and fungi, plays a crucial role in our health. However, there is still much to learn about this complex ecosystem. On this episode we talk with experts who tell us where the science is—how much we know, and how much we don’t. Two companies, Bloom Science and Seres Therapeutics, are leveraging the microbiome to develop new therapeutics. The potential of the microbiome is vast, and further research and technological advancements will continue to unlock its benefits.

22 Jun 2020COVID’s Essential Work00:29:50
The physician-wife of Roivant Sciences CEO Vivek Ramaswamy rushed back to the front lines at the pandemic’s peak — less than a month after giving birth to the couple’s first son. Meanwhile, dad cared for their newborn while testing a promising therapeutic that seeks to overcome deadly cytokine storms caused by the novel coronavirus. Hosted by Jim Greenwood.
31 Jan 2020First Dose00:42:44
One day before 16-year-old Izzy Thorpe-Wall takes her first dose of Vertex’s stunning Cystic Fibrosis breakthrough, Thorpe and her mother, Clare, open up about their emotional journey and one brave girl’s determination to stay healthy long enough to meet this day of her dreams. Hosted by Jim Greenwood.
06 Jul 2020COVID & the Plastics Problem00:32:06
Fear and misinformation about how the coronavirus is transmitted has led to dangerous backsliding in society’s efforts to address plastic pollution. But we don’t have to lose this battle to win the COVID war. A Georgia biotech is first to market with a green biopolymer material that looks and feels like plastic but dissolves in ocean water. Hosted by Jim Greenwood.
14 Sep 2020The Wrong Year to Skip Your Flu Shot00:31:13
Two potentially deadly respiratory viruses — the coronavirus and the influenza virus — will test our health care system and American common sense this fall. As millions return to school, campus and work this fall, the 2020 flu season is shaping up to be something of a pandemic pressure test for our nation. Vaccinations, social distancing and mask-wearing will be the key to containing both flu and COVID and saving countless lives. Guest hosted by Phyllis Arthur.
11 May 2020Biotech's Finest Hour (Redux)00:47:34
As the world waits for biotechnology to deliver COVID-19 treatments and a vaccine, Ambassador Deborah Birx tells BIO’s scientists: “Expectations are high because you’ve delivered for us before and I know that you can deliver for us again.” BIO chairman Jeremy Levin, a biotech pioneer, explains how the industry will rise to meet this moment. Hosted by Jim Greenwood.
15 Apr 2021I am BIO Uncut with Dr. Reed Tuckson00:16:44

This is the I Am BIO uncut series, where we bring you a full interview from Monday's episode complete and unfiltered. In this uncut episode, we share the conversation we had with Dr. Reed Tuckson, founder of the Black Coalition Against COVID-19. Check out the full episode Voices of Vaccine Hesitancy here: https://iambio.simplecast.com/episodes/voices-of-vaccine-hesitancy

05 Sep 2023The Horseshoe Crab Saved Us. Can We Save the Horseshoe Crab?00:28:02

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The horseshoe crab has endured for over 450 million years. It has survived several mass extinctions including the one that killed off the dinosaurs. One reason for their incredible resiliency is their ability to fend off bacterial infection. Their blood contains cells that clot around invading bacteria, thereby protecting them from the attacking toxins.

In this episode we talk with three experts about how this animal’s unique blue blood has become essential to modern medicine. We also talk about why horseshoe crab populations are dwindling, and what biotech is doing to address the shortfall.

10 Sep 2024A Doctor Fights to Save His Own Life: The David Fajgenbaum Story.00:21:33

David Fajgenbaum was in his third year of medical school when he was diagnosed with a rare and life-threatening disease that began shutting down his organs, bringing him perilously close to death. Although he survived the initial episode, he faced four additional relapses, each pushing him to the brink of death. In this episode, we speak with David about his relentless journey to discover the treatment that ultimately put his disease into remission. We also explore how his personal battle inspired the creation of a groundbreaking approach to help others suffering from rare diseases.

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02 Nov 2020The COVID Election00:34:12
The 2020 election will be held both during and about a global pandemic. Democratic strategist Steve Elmendorf and Republican Rai Downs preview the stakes for the biotech industry and what the outcome will mean for America’s COVID response.
19 Oct 2020The Greening of Medicine00:30:00
As the pandemic lays bare the links between human and environmental health, neuroscience leader Biogen lays out the most aggressive fossil fuel elimination plan of any Fortune 500 company while doubling down on efforts to lead on clinical trial diversity and racial equity.
20 Jul 2020The Other Pandemic: Beating “Nightmare Bugs” (Part 2 of 2)00:31:50
Viral pandemics can lead to secondary bacterial infections that kill millions, Dr. Anthony Fauci concluded after studying the 1918 Spanish flu. A century later, COVID and antibiotic resistance are proving to be a lethal combination. What are the biopharma industry and Congress doing to keep your loved ones safe from superbugs? Hosted by Jim Greenwood.
06 Feb 2024“On My Own”—Desperate to Stop a Resistant Bacterial Infection (REDUX)00:27:42

Bradley Burnam woke up one morning, looked in the mirror and found one ear twice it’s normal size and his face swollen and discolored. He would spend the next several years in and out of the hospital fighting a relentless infection that would not respond to available treatments. The experience took him from patient to mad scientist, to biotech company founder. In this episode, Bradley takes us through his desperate journey to find a cure. We also talk with the leader of an organization helping to get more antimicrobials to the marketplace.

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Visit us at https://www.bio.org/

29 Jun 2020“Herd” Immunity (Redux)00:36:14
Biotech companies are working feverishly to develop antibody therapies to provide short-term protection against COVID-19. But what if the novel coronavirus mutates and outwits traditional monoclonal antibodies? Well, that’s where the super cows come in. Hosted by Jim Greenwood.
18 Jul 2023The New Age of CRISPR (Redux)00:27:40

CRISPR has emerged as a powerful tool for altering DNA sequences with incredible precision, opening up new avenues of research into the treatment of disease. In this episode, we explore the science behind CRISPR, as well as its potential. From curing genetic disorders to creating new crop varieties, the possibilities seem endless. Our four guests today are scientists working to push these gene editing tools to the next frontier.

09 Mar 2020Trying our Patients00:35:38
As genetic sequencing gives scientists new tools to hone in on medical mysteries, Washington politicians flirt dangerously with policies that would stymie the genomic revolution while giving patients scant pricing relief at the pharmacy counter. Hosted by Jim Greenwood.
08 Oct 2024How Will We Secure our Food Future?00:26:15

As the global population approaches 10 billion by 2050, the challenge of providing safe, nutritious food is growing more urgent. Climate change is further straining food systems, impacting water availability, crop yields, and livestock health. In this episode, two experts discuss innovative biotech solutions aimed at addressing these pressing issues, offering hope for a sustainable path forward in feeding the world.

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14 Sep 2021The Elephant in the Room: What About HIV?00:29:48

For more than a year now, COVID has been society’s focus—and rightly so. But today we turn our attention to another virus—HIV. After 40 years, there is still no cure or a vaccine for the disease. In this episode, we hear from Dr. Anthony Fauci and CEO of innovative company American Gene Technologies, Jeff Galvin, about the past, present, and future of HIV treatments and medications. Is there a cure on the horizon?  

 

Guests:

Jeffrey Galvin, American Gene Technologies  

Anthony Fauci, National Institute of Allergy and Infectious Diseases

18 Oct 2022The Surprising Role of Patient Advocates in Drug Development00:20:55

Patient Advocates do more than raise money—they are active participants in the drug development process. While the ALS Ice Bucket Challenge garnered global attention, lesser-known patient advocates also flex their expertise to drive new treatments and cures.  In this episode, we talk with two moms, one who is a patient herself, about their work as partners in research and development, helping bring treatments for two rare diseases to the market. 

Susan Ruediger, Founder and Chief Mission Officer, CMT Research Foundation  

Nasha Fitter, CEO, FOXG1 Research Foundation  
 

10 May 2021Good Trouble for Good Medicine00:23:20

The COVID crisis has laid bare the inequities faced by certain populations in our health care system. It has become increasingly clear that the drug development process for a whole host of diseases often leaves these same populations behind through their absence or underrepresentation in clinical trials. This episode evaluates the problem and looks for ways to improve the process so that medicines and vaccines work for everyone who takes them. Hosted by Dr. Michelle McMurry-Heath with interviews from Gerren Wilson, Dr. Lisa Fitzpatrick, and RADM Richardae Araojo, Pharm.D., MS 

23 Nov 2020Who Gets Vaccinated First?00:26:45
As the vaccine race enters the homestretch, Pfizer and Moderna both announced that their mRNA vaccines was 95 percent effective in preventing COVID-19 during Phase 3 clinical trials. Emergency use authorization could be just weeks away. The National Academy of Sciences released an influential report about who gets vaccinated first while companies scale up vaccine production. The Academy makes a compelling case that prioritizing those with risky healthy conditions and risky, essential jobs is the surest way to mitigate death, serious disease, rising case counts and growing socioeconomic crises in vulnerable communities across the country.
21 Dec 2020The Frightening Campaign to Keep Us Unvaccinated00:42:49
Historic distrust of government institutions, a growing partisan disdain for peer-reviewed science, Russian bots, physical threats against public health officials, and an open spigot of online misinformation and disinformation raise the troubling specter that tens of millions of Americans will forgo COVID vaccination and forestall herd immunity in the United States. Learn how believers in science are uniting to fight back.
01 Nov 2022Psychedelics – Not Just For Hippies Anymore00:20:56

Not that long ago psychedelics were considered dangerous, and only enjoyed recreationally by a fringe element of society. Today, researchers are looking at drugs like psilocybin to develop treatments for depression, PTSD, addiction, and anxiety. This episode features guests steeped in the world of psychedelics who are finding new ways to treat mental health. 

Guests:

Dr. Frank Wiegand, Chief Medical Officer, Beckley Psytech

Kurt Rasmussen, Ph.D., Chief Scientific Officer, Delix Therapeutics

Clara Burtenshaw, Co-founder and Partner, Neo Kuma Ventures

20 Apr 2020COVID-19: We Were Warned00:49:35
For years, leaders on the Bipartisan Commission on Biodefense told Congress and the White House that it wasn’t a matter of if, but when, a pandemic would happen. Exploring the panel’s unheeded recommendations can give the United States a blueprint for what to do going forward to protect us from the coronavirus and future threats. Hosted by Jim Greenwood.
18 Jul 2021BONUS: Fighting the Climate Crisis Through Supply Chain Sustainability01:01:28

We are on summer break as we work to bring you another exciting season this fall. So, for the next few weeks we’re sharing some of our favorite sessions from the June 2021 BIO Digital. Today, check out our session Fighting the Climate Crisis Through Supply Chain Sustainability.  

Speakers:

Dr. Michelle McMurry-Heath

Lord David Prior, National  Health Service England

Rohin Mahtre, Biogen

Victor Dzau, MD, National Academy of Medicine 

15 Aug 2023Stand Up for Science—The Fight Against Misinformation (Redux)00:25:34

Wading through the torrent of information available online is challenging for everyone. It can be hard to know what and whom to believe. We talk with the FDA Commissioner and other leaders on the frontlines of health and science about how to be more aware of false and misleading information, and its risks to our wellbeing and future innovation. And we discuss ways to stand up for science and stop the spread of misinformation. 

14 Feb 2023Psychedelics – Not Just For Hippies Anymore (Redux)00:20:56

Not that long ago psychedelics were considered dangerous, and only enjoyed recreationally by a fringe element of society. Today, researchers are looking at drugs like psilocybin to develop treatments for depression, PTSD, addiction, and anxiety. This episode features guests steeped in the world of psychedelics who are finding new ways to treat mental health. 

Guests:

Dr. Frank Wiegand, Chief Medical Officer, Beckley Psytech

Kurt Rasmussen, Ph.D., Chief Scientific Officer, Delix Therapeutics

Clara Burtenshaw, Co-founder and Partner, Neo Kuma Ventures

07 Dec 2020CDC Vaccine Chief: No Corners Cut00:23:39
Dr. Nancy Messonnier leads the Centers for Disease Control and Prevention’s work to safely vaccinate the country. Whether the question is who to vaccine first, how to restore trust, or how to administer two doses of a vaccine stored at -70 degrees to a nation of 328 million people, she’s got the answers.
04 Jan 2021Can We Pass This COVID Test?00:36:02
Millions of travelers ignored public health warnings and packed into airports over the holidays to see their loved ones. As a result, U.S. hospitals are bracing for the deadliest COVID surge yet this month. Meanwhile, Sherlock Biosciences, which has already made history once with CRISPR, seeks to do so again with an inexpensive, accurate home test that could be a global game-changer.
17 Oct 2023How Biotechs Survive the Valley of Death00:25:05

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For biotech companies, the valley of death describes the difficult path from initial discovery to FDA approval and commercialization. It's a treacherous journey—one that even promising innovations often don't complete. Adequate funding, regulatory hurdles and the immense complexity of the biotech landscape are among the never-ending challenges faced by early stage biotechs. In this episode we talk with two biotech executives about what it’s like to struggle and survive in this rough-and-tumble industry. 

10 Jan 2023Antimicrobial Resistance: The Silent Pandemic (Redux)00:26:53

We are on the precipice of a looming crisis. Antimicrobial resistance (AMR) is the evolution of deadly pathogens like bacteria and fungi to resist all current antimicrobial medicines. In this episode, we talk about how the dwindling supply of new antibiotics is fueling this silent pandemic, and why we need a continued pipeline of new antibiotics to avoid this crisis.

Guests:

Ankit Mahadevia, Spero Therapeutics

Henry  Skinner, AMR Action Fund

Mary Dwight, Cystic Fibrosis Foundation 

20 Dec 2022New Season of I am BIO; plus Hope for Alzheimer's (Redux)00:22:47

I am BIO will begin a new season of exciting topics on Feb 28. During our hiatus, we are bringing back some of our most popular episodes beginning with “Hope for Alzheimer's.”

Alzheimer’s disease is a heartbreaking diagnosis and tragically there is no cure. But every day, researchers, scientists and the medical community are working to change that. In this episode, we speak with three guests who are fighting to bend the trajectory of Alzheimer’s disease and, in doing so, offering hope for the millions suffering from this devastating illness.

28 Dec 2020First Dose (Redux)00:42:30
One day before 16-year-old Izzy Thorpe-Wall takes her first dose of Vertex’s stunning Cystic Fibrosis breakthrough, Thorpe and her mother, Clare, open up about their emotional journey and one brave girl’s determination to stay healthy long enough to meet this day of her dreams. Hosted by Jim Greenwood.
30 Mar 2020COVID-19 Could Generate 1st Computerized Vaccine00:59:46
Futuristic biotech Moderna is the first to clinically test a coronavirus vaccine, created in weeks using only the virus’ genetic code. The company’s messenger RNA breakthrough may be just in time as a former CDC director warns that animal viruses spilling over to humans is the new normal. Hosted by Jim Greenwood.
14 Dec 2020Destroying COVID's Genome (REDUX)00:33:50
Alnylam Pharmaceuticals, which take its name from the center and brightest star in Orion’s Belt, is working on an RNAi therapy to destroy the genome of the novel coronavirus — and with it, its ability to replicate and kill. Hosted by Jim Greenwood.
26 Oct 20201st Alzheimer’s Prevention Trial: Thwarting the Brain’s Betrayal00:29:54
The first clinical study dedicated to preventing Alzheimer’s disease is now in its late stages. The participants are 300 members of the same Colombian family with a rare gene mutation that gives them a 100 percent chance of developing Alzheimer’s disease. Armed with this new data, could neuroscientists be closing in on an elusive breakthrough to defeat neurodegeneration?
28 Feb 2023Cracking the Code on Pain Relief00:26:02

Imagine living with excruciating pain that prevents you from walking or doing the things most of us take for granted. We all experience pain, and 50 million people cope with chronic, debilitating pain. The market for pain therapies is estimated at $74 billion. And yet, investment in new pain and addiction treatments is falling short of what is needed, according to a new BIO report, which shows a 44% decrease in clinical drug programs for pain over the past five years. Our guests on this episode talk about the challenges of living with and treating pain, as well as research and development on new, non-addictive and safer pain therapies. 

15 Jun 2020Deep Diving for COVID Cures00:43:23
By studying our earliest evolutionary ancestors in the ocean, marine biotech researchers are gaining fresh insights about everything from anti-virals to coronavirus nasal swab testing to the inner workings of our adaptive immune systems. Learn what sea sponges, lugworms and sharks can teach us about improving human health during this crisis. Hosted by Jim Greenwood.
12 Mar 2024What We Know About the Microbiome00:27:25

The gut microbiome, which consists of trillions of bacteria, viruses, and fungi, plays a crucial role in our health. However, there is still much to learn about this complex ecosystem. On this episode we talk with experts who tell us where the science is—how much we know, and how much we don’t. Two companies, Bloom Science and Seres Therapeutics, are leveraging the microbiome to develop new therapeutics. The potential of the microbiome is vast, and further research and technological advancements will continue to unlock its benefits.

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13 May 2021I am BIO Uncut with Gerren Wilson00:50:52

This is the I Am BIO Uncut Series, where we bring you a full interview from Monday's episode complete and unfiltered. In this Uncut episode, we share the conversation we had with Gerren Wilson, Head of Inclusion & Partnering in the Chief Diversity Office at Genentech, the pharmaceutical biotech company. Check out the full episode here: https://iambio.simplecast.com/episodes/solving-an-unfashionable-problem

05 Apr 2022Science Helped Save the World from COVID. What will Vaccine Technology do Next?00:24:39

2021 was the unofficial year of mRNA—and deservedly so. But the science behind the technology is not always easy to understand. In this episode, we will dive into the miracle technology that saved countless lives and talk about what it holds for the future. We also speak to a biotech company about its non-mRNA vaccine technology for COVID and why the healthcare ecosystem will always need multiple options.

18 May 2020COVID X-FACTOR00:31:50
The diversity of our adaptive immune system is why people are reacting so differently to the novel coronavirus. No two people present the virus the exact same way to their immune systems. We’ve evolved in this way as humans to ensure no virus can eradicate our species. Hosted by Jim Greenwood.
15 Nov 2022Microbes, Bioplastics … and Art: Solutions to Plastic Pollution00:24:19

Plastic is polluting our waterways and oceans, but biotechnology may deliver solutions. Plant-based bioplastics that can break down in months are one solution. Another is mighty microbes bioengineered to speed up consumption of plastic. This episode spotlights scientists, companies and even a filmmaker and artist who are working in different ways to tackle the growing problem of plastic waste. 

Guests:

Scott Tuten, Chief Marketing and Sustainability Officer, Danimer Scientific

Andrew Held, Vice President of Engineering & Business, Virent

Dr. Tae Seok Moon, Associate Professor of Energy, Environmental & Chemical Engineering, Washington University in St. Louis, Founder and head of the Scientific Advisory Board, Moonshot Bio

Ben Lear, Independent Film Producer/Director

27 Apr 2020Vaccines are a Virtue00:33:12
As biotech researchers work around the clock on a covid vaccine, ill-informed, anti-science anti-vaxxers must be denounced and excoriated in the public square. BIO’s head of infectious disease policy Phyllis Arthur administers a vital dose of vaccine education, because none of us is safe until we all are. Hosted by Jim Greenwood.
28 Mar 2023Accelerating Hope: The Pathway for Cures00:23:00

When people were dying from AIDS in the 1980s and 90s, Congress found a way to expedite the drug approval process and saved countless lives. Established in 1992, the Accelerated Approval Program allows the FDA to speed approval of drugs for patients with serious and life-threatening conditions. In this episode we talk with the father of children with a rare disease, a company CEO working to treat rare diseases and two policy experts on Accelerated Approval.

24 Aug 2020A Nation Traumatized00:27:45
The pandemic has unleashed overwhelming levels of fear, isolation, anxiety and loss in our society. A CDC mental health survey this summer found that 1 in 10 people had “seriously considered” suicide within the last month. As America comes to grips with the severity of our ongoing mental health crisis, telepsychiatry has emerged as a virtual lifeline to help patients access treatment from home.
17 Mar 2021I Am BIO Will Be Right Back!00:01:34

The I AM BIO podcast has gone on a brief hiatus while we reimagine the format, dream up interesting topics, and dive deep with riveting guests. Listen for a sneak preview into the new season. 

04 Jun 2020What Can Iceland Tell Us About COVID?00:31:33
The people of Iceland — a country of 360,000 — eagerly volunteered for genetic research on how the coronavirus affects a homogeneous population. Amgen’s work in the Land of Fire and here at home could deliver answers and antibodies to help mitigate the pandemic threat. Hosted by Jim Greenwood.
23 Apr 2024Editing Cells Within the Body—a New CRISPR Frontier00:21:21

With its potential to expand the horizons of what’s possible for patients, CRISPR is the new darling of biotech. Reaching an important milestone in 2023 with the FDA approval of a sickle cell treatment using CRISPR, the technology is poised to break new barriers for treating patients in the near future. In this episode we talk with two companies working together on the next generation of CRISPR: editing cells within the body.  We discuss the progress and the challenge in making this breakthrough a reality. 

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12 Oct 2020Bullish00:29:33
Biotechnology investors, armed with troves of data and “misfit” minds, have become key-decision makers in everything from when to open up the states to which medicines can turn the tide in this pandemic the quickest. As the BIO Investor Forum kicks off virtually today, a biomedical renaissance has Wall Street bullish on biotech’s future.
19 Nov 2024The Faceless Middleman Between You and Your Doctor00:26:43

A troubling disconnect between medical expertise and insurance mandates is putting patients' health at risk. Policies like step therapy and prior authorization are forcing individuals into treatments not recommended by their doctors—often with devastating consequences. In this episode, we hear from a patient who endured months of suffering due to her insurer's 'fail-first' requirements. We also talk with a doctor navigating this impossible system and a biotech leader fighting to ensure innovative treatments reach the patients who need them most. 

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13 Apr 2020Biotech’s Finest Hour00:52:36
As the world waits for biotechnology to deliver COVID-19 treatments and a vaccine, Ambassador Deborah Birx tells BIO’s scientists: “Expectations are high because you’ve delivered for us before and I know that you can deliver for us again.” BIO chairman Jeremy Levin, a biotech pioneer, explains how the industry will rise to meet this moment. Hosted by Jim Greenwood.
03 Oct 2023Biotech Women Striking at the Glass Ceiling00:24:38

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The biotech industry offers unique opportunities for women to advance as executives and entrepreneurs. There are headwinds, however, including unequal access to venture capital. In this episode, we talk with three executives who are part of a wave of women-led companies in biotech. Our guests speak to why women’s leadership matters and the barriers that remain to breaking the glass ceiling. They also tell us about a new networking initiative—the biotech sisterhood—to catalyze women’s success in corporate leadership and mentor the next generation of women executives.    

For more resources, visit Women In BIO, Lean In, and The Economist’s glass-ceiling index

20 Jun 2023Why AI and Biotech are BFFs (Redux)00:21:49

The convergence of Artificial Intelligence (AI) and biotechnology has emerged as one of the most exciting and transformative areas of science. Researchers are developing new tools and technology that could bring about breakthroughs to revolutionize the fields of medicine and health care.  In this episode, we talk with scientists who are using AI to unlock new possibilities in the search for novel drugs, cures, and treatments.

25 Apr 2023Is Space the Next Frontier for Biotech?00:27:18

The International Space Station has been orbiting in lower earth since 1998 and has been continually inhabited since November 2000. The ISS was originally conceived as a staging base for future missions into deep space. As it turns out, lower earth orbit is an ideal setting for scientific research, from physics and meteorology to astronomy and the life sciences. In this episode we talk with three scientists whose projects are using lower earth orbit to deepen our knowledge of biotechnology and its benefits for mankind.

09 Nov 2020A Time to Heal00:31:28
Joe Biden’s election as 46th President of the United States is a chance to soothe our bitter body politic so we can unite to defeat an enemy that infects and kills without regard to partisan affiliation.
16 Nov 2020An Alternative to Flying Dirty (Redux)00:39:57
While Swedish climate activist Greta Thunberg has kindled a global dialogue about the ravages of climate change and the role of airline emissions, a Colorado biotech is putting forward a jaw-dropping alternative to flight shaming: actual jet fuel with no carbon footprint. Hosted by Jim Greenwood.
31 May 2022Investors Become Goldilocks in a Bear Market00:25:50

Current market trends have put investors in a “flight-to-safety” mentality, especially when it comes to biotech companies. What does this mean for getting biotech innovations to the marketplace? This episode explores the daunting challenge of raising capital in a bear market.

Speakers:

  • Bill Newell, Sutro Biopharma
  • Dr. Lisa Drakeman, Biotech Entrepreneur
  • Sougato Das, PRISM.science

 

20 Sep 2022Data Storage Crisis: DNA to the Rescue00:25:10

You might be surprised to learn that data storage currently requires huge amounts of land and energy, and we're running out of both. In this episode, we speak with a small group of researchers who are working to revolutionize the way we store the massive amounts of data we produce every day. Their solution: use DNA.

Speakers:

  • Emily Leproust, Twist Bioscience
  • Jeff Nivala, University of Washington
  • Kyle Tomek, DNAli Technologies
03 Apr 2020Sickle Cell Saviors01:02:27
Need a dose of inspiration in a time of national tragedy? A remarkable biotech breakthrough from Global Blood Therapeutics offers fresh hope to patients living with sickle-cell disease. Hosted by Jim Greenwood.
09 Nov 2021Pressure on STEM from Covid and Inequity00:27:18

Not only do we need STEM students, but we also need them from every corner of the population, because innovation thrives through diverse perspectives; through the people who bring both their talents and backgrounds to the work.  In this episode, we dig into the importance of kids learning about STEM early in their educations, the impact of the pandemic on students and teachers, and what the future of STEM education looks like. 

Guests:

Barak Balva, Sanofi

Kimberly Bryant, Black Girls Code

Jen Colvin, Learning Undefeated 

Jo Webber, STEMconnector

 

14 Mar 2023Why AI and Biotech are BFFs00:21:49

The convergence of Artificial Intelligence (AI) and biotechnology has emerged as one of the most exciting and transformative areas of science. Researchers are developing new tools and technology that could bring about breakthroughs to revolutionize the fields of medicine and health care.  In this episode, we talk with scientists who are using AI to unlock new possibilities in the search for novel drugs, cures, and treatments.

29 Nov 2022Let’s Get Uncomfortable: Talking About Women’s Health00:24:47

Talking about women’s health has been a taboo subject for some time, contributing to a lack of innovation in the sector. Still today, many are uncomfortable discussing the topic. Consequently, only 2% of medical products in the pipeline are for women’s health and only 2% of all venture capital dollars go into developing these products. In this episode, we talk with two women in biotech who are trying to change that narrative and infuse more investment in innovations that meet the needs of half the population.

Sabrina Martucci Johnson, CEO
Daré Bioscience

Elizabeth Baily, Managing Director
RH Capital

 

28 Nov 2023The Horseshoe Crab Saved Us. Can We Save the Horseshoe Crab? (REDUX)00:28:02

The horseshoe crab has endured for over 450 million years. It has survived several mass extinctions including the one that killed off the dinosaurs. One reason for their incredible resiliency is their ability to fend off bacterial infection. Their blood contains cells that clot around invading bacteria, thereby protecting them from the attacking toxins.

In this episode we talk with three experts about how this animal’s unique blue blood has become essential to modern medicine. We also talk about why horseshoe crab populations are dwindling, and what biotech is doing to address the shortfall.

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07 May 2024Listener takeover: Your Biotech Questions Answered00:21:29

YOU asked, and we answered. In this episode, we had our experts on standby to answer questions from you, our listeners. We discuss topics ranging from the safety of genetically modified foods (GMOs), to the new era of personalized medicine, feeding the world by 2050, and even what makes start-up companies attractive to investors.

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18 Jan 2021BIO Blocks President’s Rule To Ration Drugs In Medicare00:27:33
Trailing in the polls this fall, President Trump dusted off the 2016 campaign playbook and went after the drug companies again. But channeling anger at the companies the whole world is depending on to end the pandemic was always dicey politics. Post-election, the Trump administration hastily issued a final rule setting Medicare Part B reimbursement rates at the lowest levels charged by counties in the developed world, which ration medicines and leave the sick untreated. BIO took the administration to court, and we won when a federal court issued an injunction blocking the rule.
31 Jan 2023Green Fuels Have Taken Off (Redux)00:19:59

Last December, a United Airlines’ flight from Chicago to Washington DC was the first ever passenger flight powered with 100% sustainable aviation fuel. The achievement demonstrated the potential for the aviation sector to reduce its carbon footprint. Our guests in this episode each played a key role in in helping the airline reach this exciting milestone.

25 May 2020Bats Don’t Have Passports00:33:01
Modernity is plowing new frontiers, bringing us closer to exotic wildlife rich in viruses that our immune systems have not evolved to fight. Preventing future pandemics will require global cooperation, local action and a comprehensive strategy to monitor infectious disease hotspots to reduce the risk of zoonotic disease. Hosted by Jim Greenwood.

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