Cancer Straight Talk (Memorial Sloan Kettering Cancer Center)

A recent clinical trial for rectal cancer headed up by Memorial Sloan Kettering has grabbed the attention of medical oncologists and cancer scientists around the world. Like a miracle, in a subset of patients with the right genetic makeup, an IV infusion of an immunotherapy caused a complete remission. The doctors were shocked. The cancer disappeared in every single patient enrolled on trial. The results are so impressive they were published in The New England Journal of Medicine and featured at the nation’s largest gathering of clinical oncologists in June 2022.

In this episode, Dr. Diane Reidy-Lagunes speaks with the designers of this study, Drs. Andrea Cercek and Luis Diaz, on what this groundbreaking news means for cancer patients and the scientific community moving forward.

Learn more about MSK’s Center for Young Onset Colorectal and Gastrointestinal Cancer

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In this episode, Dr. Diane Reidy-Lagunes speaks with Dr. Jeanne Carter, clinical psychologist and sexual health therapist, and Ashley Arkema, gynecological nurse practitioner, about women’s sexual health during and after cancer treatment. This episode includes an honest and frank conversation about the impact of treatment on a woman’s physical and emotional sexual health. Our experts provide helpful advice and tips. Some content may not be suitable for children.

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George Kolasa was living his dream life as a fashion executive in New York City when in February 2022, he was diagnosed with glioblastoma – the most common form of brain cancer. In this special episode, George and his husband Justin take us on their journey as cancer patient and caregiver as it has unfolded in real time over the past year.

We see George quickly evolve from accepting his disease to raising hundreds of thousands of dollars for rare cancer research through Cycle for Survival. George finds purpose in his diagnosis by helping others and spreading his message of hope, even as he confronts reality. As George’s memory, speech and ability to walk declines, Justin leans in to the challenges of being a caregiver and also learns the importance of asking for help. As we follow George to his many tests, treatments, and checkups with his neuro-oncologist Alexandra Miller and her compassionate team of nurses, we witness the special bond formed between patients and care teams at MSK and see a couple making the most of every moment together, living their life with dignity, purpose, and love.

Shortly after this podcast was completed, George passed away. We thank him and Justin for generously sharing their story to raise awareness and support for research. George was a remarkable person, whose legacy is everlasting.

Watch the video version of this podcast here.

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Twenty years ago, Dr. Charles Sawyers played a pivotal role in the development of a game-changing cancer drug that has gone on to save millions of lives and open doors for research and innovation. In this episode, Dr. Diane Reidy-Lagunes talks with Dr. Sawyers about what’s next in the field of cancer pharmaceuticals. Is another silver bullet on the horizon?

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Spanish episode #4   |   Episodio #4 en español

En este episodio, la Dra. Diane Reidy-Lagunes habla con el Dr. José Flores, cirujano urológico de MSK, sobre el tema de la salud sexual de los hombres después de un diagnóstico de cáncer. Es un tema que a menudo se pasa por alto, pero es de vital importancia. Exploran el amplio espectro de la disfunción sexual, cómo abordar este delicado tema con su médico y despejan los mitos y tabúes comunes que lo rodean. Descubra cómo los pacientes y los médicos están encontrando soluciones para mantener una vida sexual saludable antes, durante y después del tratamiento contra el cáncer. 

Vea todos los episodios de Cancer Straight Talk en Español.

A Man's Guide to Sex and Cancer 

In this episode, Dr. Diane Reidy-Lagunes talks with Dr. José Flores, urologic surgeon at MSK, about the often overlooked but vital topic of men's sexual health after a cancer diagnosis. They delve into the broad spectrum of sexual dysfunction, how to address this sensitive subject with your doctor, and break down common myths and taboos that surround it. Discover how patients and doctors are finding solutions to maintaining a healthy sex life before, during and after cancer treatment.

See all episodes of Cancer Straight Talk en Español.

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In this episode, Dr. Diane Reidy-Lagunes speaks with Dr. Jun Mao, Chief of MSK’s Integrative Medicine Service, and Jason Hou, herbalist and acupuncturist at MSK, to break down the facts about alternative medicine—an approach that combines conventional cancer treatments like surgery, radiation, chemo, immunotherapy and targeted treatments, with holistic therapies like acupuncture, mindfulness, natural herbs and supplements. They tackle common misconceptions about alternative medicine, explaining what the science says, what’s safe, and what to avoid. Offering guidance on how these natural therapies can complement other cancer treatments – and how to recognize misleading claims – this episode empowers patients and caregivers with the knowledge they need to make informed choices about their cancer care and the use of alternative therapies. 

Resources:
MSK's "About Herbs" Database
MSK's Meditation Library
MSK's Integrative Medicine at Home Program

Episode Chapters:
2:05 - Integrative vs. Alternative medicine
3:14 - Which integrative therapies are right for me?
6:29 - Do these therapies actually treat/kill cancer?
7:59 - The very real benefits of human connection
9:36 - Ivermectin
10:18 - Cannabis oil and Castor oil
11:55 - Vitamin C
13:53 - Turmeric
14:30 - Medicinal mushrooms
14:59 - Ashwagandha
15:42 - Traditional Chinese medicine
18:25 - The dangers of "Why not try?"
21:49 - Resources: herbs, meditation, yoga, music, etc.

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In this episode (part 2 of 2), Dr. Diane Reidy-Lagunes speaks with a team of MSK experts to explore the complexities of breast cancer treatment and life afterwards. Breast medical oncologist Dr. Julia Brockway-Marchello and nurse Jenna Galinsky explain chemotherapy and hormone therapy, their potential side effects, and ways they can be alleviated. Nurse Adriana Olivo discusses how survivors can cope with emotional challenges, like the fear cancer will come back. Breast cancer patients and survivors offer advice on asking for support while navigating life during and after cancer treatment.

Listen to episode 52 "Breast Cancer Treatment Part 1: Surgery, Radiation and Reconstruction"

Listen to episode 39 "How to Manage Side Effects During Cancer Treatment: Fatigue, Hair Loss, Skin Care and More"

Listen to episode 12 "A Woman's Guide to Sex and Cancer"

Episode Chapters:
1:44 - Why use some treatments over others?
2:55 - Types of breast cancers & their treatments
4:50 - Patient testimonial on self-advocacy
6:02 - Length of treatment & why it can change
7:38 - Quality of life advice during treatment
9:10 - Mitigating chemotherapy side effects
9:57 - Maintaining sexual health during treatment
10:46 - When is taking estrogen a bad idea?
13:07 - Quality of life concerns & when to switch meds
16:16 - Mitigating hormone therapy side effects
17:32 - Patient testimonial on finishing treatment
18:22 - Managing fear & life after treatment
19:34 - Mitigating long-term side effects of treatment
21:24 - Patient testimonial on fear of recurrence
22:49 - Why scanning for recurrence isn't recommended
26:25 - The reason for all this: live your life!

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In this episode, Dr. Diane Reidy-Lagunes chats with medical oncologist Dr. Juan-Manuel Schvartzman about the cellular damage that causes cancer. Can we find its Achilles’s heel?

For more information or to ask a question, please visit MSKCC.org/podcast

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We’re listening back to one of our favorite episodes from December 2022. While the holidays are meant to be a season of celebration, reflection and spending time with family and friends, it can also be a time of anxiety, grief or loneliness for those living with the reality of cancer. How does one find peace and meaning in the swarm of emotions that cancer brings up? In this episode, Dr. Diane Reidy-Lagunes and MSK chaplain Brian Kelly share their thoughts on what makes life meaningful and how to find your light in the darkest of times.

This episode features a reflection from Anthony, an MSK patient. Sadly, earlier this year, Anthony passed away. We thank him for sharing his beautiful words and send our love to his family.

Read "Coping With Grief: 7 Things to Remember When Dealing with Loss"

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In this episode, Dr. Diane Reidy-Lagunes speaks with MSK colorectal surgeon Dr. Martin Weiser. They discuss what to expect when approaching surgery, innovations in the field of precision surgery, and how to make an informed decision.

For more information or to ask a question, please visit MSKCC.org/podcast

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In this episode, Dr. Diane Reidy-Lagunes sits down with Dr. Elizabeth Comen, author of "All in Her Head: The Truth and Lies Early Medicine Taught Us About Women's Health and Why It Matters Today." They discuss ways to empower women to advocate for their health when talking to doctors, and how a historic gender bias in medical research has influenced practices today. Tune in for an insightful conversation on tackling stigmas and reshaping the narrative around women's health.

Listen to Episode 12: "A Woman's Guide to Sex and Cancer"

Listen to Episode 30: "Achieving Excellent Healthcare for All: A Candid Conversation with MSK’s President & CEO, Dr. Selwyn Vickers"

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In this episode, Dr. Diane Reidy-Lagunes sits down with MSK’s Chief of Computational Oncology, Sohrab Shah, and Chair of the Department of Radiology, Lawrence H. Schwartz, to discuss the transformative role of artificial intelligence in cancer care. They explore how A.I. is making a real impact in radiology, from reducing the time patients spend getting scans to detecting cancerous lesions with more accuracy. By complementing researchers’ expertise, A.I. is already offering breakthroughs in early detection, as well as personalized predictions about the best treatment for patients. This conversation is a must-listen for those eager to explore how technology is leading to better patient care.

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In this episode (part 1 of 2), Dr. Diane Reidy-Lagunes speaks with a team of MSK experts to demystify three breast cancer treatment options: surgery, radiation, and reconstruction. Breast surgeon Dr. Tracy-Ann Moo explains the difference between a lumpectomy and a mastectomy, and why one isn’t always better than the other. Radiation oncologist Dr. Michael Bernstein discusses the role of radiation therapy in the treatment of breast cancer. Plastic and reconstructive surgeon Dr. Michelle Coriddi describes various breast reconstruction and preservation techniques, which can help patients maintain a positive body image after treatment.

Subscribe to Cancer Straight Talk to be notified when Part 2 airs, covering chemotherapy, hormone therapy and survivorship for people with breast cancer.

Episode Chapters:
1:27 - Surgery options: lumpectomy vs. mastectomy
2:32 - Family history, genetics, and BRCA mutation
3:30 - Which surgery has the best outcomes?
5:16 - Surgery patient testimony 
6:46 - Nipple-sparing mastectomy
7:36 - What is radiation?
8:49 - Why is radiation needed?
10:11 - What does a typical radiation plan entail?
11:19 - Radiation patient testimony
12:38 - Radiation side effects & how to mitigate them
14:25 - Exercise during treatment and recovery
15:10 - Reconstruction options after surgery
18:22 - Recovery after reconstruction
19:10 - Insurance coverage for breast reconstruction
19:31 - Reconstruction patient testimony
20:58 - Nipple tattoos and 3D areola reconstruction
22:00 - Surveillance and risks of breast implants
23:02 - Advice for patients

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Mark Lewis was inspired to become a cancer doctor after living through the highs and lows of his father’s cancer journey. On day one of his oncology fellowship, Mark developed an abdominal pain and was suddenly diagnosed with the very same cancer that took his father; a cancer, he learned, that can be passed down to his children as well. In this episode, Dr. Diane Reidy-Lagunes chats with Dr. Mark Lewis, Director of Gastrointestinal Oncology at Intermountain Healthcare, about how his diagnosis has changed the way he practices medicine, and what every person should know about genetic testing and hereditary cancers.

Hear more from Dr. Mark Lewis on his weekly podcast, "Is It Serious?"

Make an appointment with MSK's Clinical Genetics Service here.

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A cancer diagnosis is a life-altering event for anyone, especially for adolescents and young adults who are just getting their bearings in life. In this episode, Dr. Diane Reidy-Lagunes sits down with MSK social worker Hadley Maya to discuss the effects of a cancer diagnosis on a young person’s identity, career, relationships and more.

Learn more about MSK's Center for Adolescent and Young Adult Cancers.

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In this episode, Dr. Diane Reidy-Lagunes speaks with MSK physician-scientist Dr. Karuna Ganesh and epidemiologist Dr. Caitlin Murphy about the troubling rise in cancer rates among younger generations, specifically people born in the 1980s (Gen X) and 1990s (Millennials). The latest research suggests prenatal exposures, environmental toxins, and various lifestyle factors may be contributing to the alarming trend of young people getting cancer earlier in their lives than previous generations. These insights could reshape our understanding of cancer risk and impact our approach to screening and treatment in the future.

Learn more about how MSK is finding solutions through the Lisa and Scott Stuart Center for Adolescent and Young Adult Cancers and MSK’s Center for Young Onset Colorectal and Gastrointestinal Cancer

Episode Chapters:
2:01 - In utero and early life exposures
5:38 - Microbiome risk factors
8:15 - Environmental chemicals
9:56 - Cross-generational research methods
11:40 - Are young adult cancers unique on a cellular level?
14:02 - Moving past the "smoking gun" mindset
15:37 - What is the exposome and why is it promising?
17:01 - Who's responsible for monitoring risk factors?
20:19 - Updating screening guidelines

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In this special episode, Dr. Diane Reidy-Lagunes sits down with renowned journalist and cancer screening advocate Katie Couric at The Paley Center for Media in New York City. After losing her first husband to colon cancer in 1997, Katie made history when she received her first colonoscopy on-air as host of the Today show, inspiring millions of Americans to do the same in a phenomenon known as the Couric Effect. Her role as the “screen queen” has continued ever since, taking on new meaning last year when she revealed her own breast cancer diagnosis.

Learn more about breast cancer screening

Learn more about colon cancer screening

Watch the extended conversation with Katie on MSK's YouTube channel

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In this episode, Dr. Diane Reidy-Lagunes talks to medical oncologist and scientist Dr. Jedd Wolchok and cancer survivor Grace Dunn. Together, they help decode the emerging new defense against cancer: immunology.

For more information or to ask a question, please visit MSKCC.org/podcast

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In 2005, Andrew McMahon was on top of the world: His rock band Something Corporate had three albums under its belt, and Andrew was busy recording the debut soon-to-be smash album under his new solo moniker, Jack's Mannequin. Then, suddenly, he couldn't sing. At just 22, Andrew was diagnosed with acute lymphoblastic leukemia. In this episode, Dr. Diane Reidy-Lagunes talks with Andrew and his wife, Kelly, about their struggle to save not just Andrew's life but also their marriage, sense of purpose, and identities beyond the patient and caregiver roles they had gotten so used to.

Learn more about MSK's Survivorship Programs.

Learn more about MSK's Center for Adolescent and Young Adult Cancers.

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Spanish episode #2   |   Episodio #2 en español

Somos lo que comemos, y no hay duda de que ciertos estilos de vida aumentan el riesgo de padecer cáncer. Entonces, ¿cómo nos ayuda la comida a reducir ese riesgo? ¿Dónde puedo obtener ayuda para encontrar alimentos saludables? ¿Y qué debo comer si tengo cáncer? Médica oncóloga Diane Reidy-Lagunes habla con sus colegas de MSK, la nutricionista Karla Giboyeaux y la gastroenteróloga Delia Calo, sobre cómo formar buenos hábitos en nuestra vida diaria para reducir el riesgo de cáncer — incluso qué comprar y cocinar y la programación de exámenes regulares para la detección de cáncer.

Programa tu examen de detección de cáncer aquí.

Obtén más información sobre el Centro Ralph Lauren aquí.

Vea todos los episodios de Cancer Straight Talk en Español.

Lowering Your Cancer Risk with a Healthy Diet

We are what we eat, and there’s no doubt that certain lifestyles increase the risk of developing cancer. So how does food help us reduce that risk? Where can I get help finding healthy food? And what should I be eating if I have cancer? In this episode, medical oncologist Diane Reidy-Lagunes talks with her MSK colleagues, nutritionist Karla Giboyeaux and gastroenterologist Delia Calo, about building good habits in our daily lives to reduce the risk of cancer — from grocery shopping and cooking to scheduling regular screenings.

Schedule your cancer screening here.

Learn more about the Ralph Lauren Center here.

See all episodes of Cancer Straight Talk en Español.

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Dr. Selwyn Vickers was named President and CEO of Memorial Sloan Kettering Cancer Center in September 2022. His vision of a future with equal access and better outcomes for all has inspired the faculty and staff at MSK. In this episode, Dr. Diane Reidy-Lagunes gets to know Dr. Vickers’ philosophy on achieving health equity, from restoring trust in the system, to overcoming racial bias in the clinic, to improving people’s access to top hospitals like MSK.

Subscribe to Cancer Straight Talk from MSK to be notified of new episodes.

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You’ve received a cancer diagnosis. Now what? For George Kolasa, it was obvious: use his glioblastoma diagnosis for good. “I’ve been chosen,” he says. Since February, George has been spreading his message of hope, acceptance and overcoming adversity on social media, while husband Justin has taken on his new role as caretaker with military-grade precision and organization.

In this episode, Dr. Diane Reidy-Lagunes talks with George and Justin on their journey to accepting a life they never planned for, plus what advice they have for families going through the same thing.

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Recent research has shown that most, if not all, high grade serous ovarian cancers originate in the fallopian tubes. With no pronounced symptoms or tests to catch it early, ovarian cancer is usually detected in women with an average risk of cancer and in highly advanced stages. In this episode, gynecologic surgeons Kara Long-Roche (MSK) and Rebecca Stone (John Hopkins) join Dr. Diane Reidy-Lagunes to discuss a procedure that substantially decreases a person’s lifetime risk of developing the most common and deadly type of ovarian cancer: a salpingectomy, or removal of the fallopian tubes. Because of the simplicity of this procedure, Drs. Long-Roche and Stone are advocating for salpingectomies to become routine in women who are seeking permanent birth control, and opportunistic at the time of other abdominal surgeries.

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A cancer diagnosis can be frightening and overwhelming. Medical oncologist Diane Reidy-Lagunes talks with patients and experts to help better understand this disease. Our mission is to educate and empower people to make the right decisions and live happier, healthier lives.

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Navigating the dating world after a cancer diagnosis can be tricky. From the fear of disclosing a diagnosis to insecurities around bodily changes, to the emotional baggage patients feel they’re bringing into a relationship, diving back into the dating pool comes with its challenges. In this episode, Dr. Diane Reidy-Lagunes sheds light on the universality of these fears with advice from MSK psychologist Talia Zaider and cancer survivor Irene Dimatulac. Through personal anecdotes and expert insights, they provide a nuanced look at the dating experience for cancer survivors and offer guidance for how to move forward with readiness and self-love.

Listen to our episode on Women’s Sexual Heath and Cancer.

Listen to our episode on Men’s Sexual Heath and Cancer.

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In this episode, Dr. Diane Reidy-Lagunes sits down with two physician-scientists researching vaccines and novel immunotherapies, Dr. Vinod Balachandran and Dr. Dmitriy Zamarin. They discuss the power of the body’s immune system to prevent and treat cancers, the difference between preventative and therapeutic vaccines, which cancers are treatable with vaccines, and the challenges that lie ahead.

Read more about Dr. Balachandran’s recent research into a vaccine for pancreatic cancer.

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In this episode, Dr. Diane Reidy-Lagunes sits down with journalist, author and stage-four melanoma survivor, Mary Elizabeth Williams, to discuss what it was like being part of a phase-one clinical trial, how clear communication can affect health outcomes, how guilt often accompanies survival, and what not to say to a cancer patient. Mary Elizabeth’s book is A Series of Catastrophes and Miracles.

Listen to our episode with Mary Elizabeth’s doctor, Jedd Wolchok.

Learn more about MSK's Survivorship Programs.

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In this empowering episode, Dr. Diane Reidy-Lagunes speaks to a panel of onco-fertility experts about preserving fertility during cancer treatment. MSK oncologists Dr. Julia Brockway-Marchello and Dr. José Flores discuss the timing and options for patients who want to have biological children without delaying life-saving cancer treatments, like radiation and chemotherapy. Dr. Lucky Sekhon, reproductive endocrinologist and fertility specialist at RMA of New York, explains the safety, success rates, and evolving technologies used to freeze eggs and bank sperm. A nurse from MSK's fertility preservation program, Lauren Martino, explains what patients should know about the cost and the importance of early referrals. Emotional stories from cancer survivors, new parents, and patient advocates offer hope to anyone, man or woman, who faces cancer and wants to have a baby someday.

Episode Chapters:
2:26 - Timeline from diagnosis to preservation
3:17 - Why fertility preservation is recommended
4:27 - Preservation options for women
5:58 - Egg retrieval success rates
7:31 - Testing embryos for cancer-causing genes
9:12 - Breast cancer patient testimonial
10:23 - Embryos or eggs: Which is better to freeze?
12:39 - Testicular cancer patient testimonial
13:26 - Preservation options and timeline for men
14:43 - Will the preservation process delay my treatment?
16:14 - Will the preservation process worsen my cancer?
17:25 - Preservation options during/after treatment
19:25 - Pregnancy success rates for various methods
22:40 - Cost of sperm banking
23:16 - Cost of egg and embryo freezing
24:41 - Insurance and financial grants
28:23 - It takes a village

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Every year, tens of thousands of people across the country hop on stationary bikes to raise money for rare cancer research through Cycle for Survival, MSK’s largest fundraising event of the year. With the help of founding partner Equinox, Cycle for Survival has raised nearly $300 million since 2007. But how does pedaling raise money? And who is that money helping? In this episode, Dr. Diane Reidy-Lagunes sits down with the cofounder of Cycle for Survival Dave Linn, as well as rare cancer survivor and one of the movement’s biggest cheerleaders (and actual winner of TV’s Survivor: Africa), Ethan Zohn, to hear about their personal cancer stories and the power of Cycle for Survival. 

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In this episode, Dr. Diane Reidy-Lagunes is joined by Dr. Erica Lee, a dermatologist and Mohs surgeon at MSK, to discuss misconceptions around who can get skin cancer, how it presents on different skin types, and practical sun safety tips to help prevent skin cancer. They break down the different types of skin cancer, including basal cell carcinoma, squamous cell carcinoma, and melanoma. They also hear from Jocelyn, a Hispanic melanoma survivor who shares her surprise of being diagnosed with melanoma despite her Hispanic background, emphasizing the importance of routine skin checks for people of all skin types.

Episode Chapters:
1:30 - Types of skin cancer
4:39 - Who's most at risk?
7:13 - Warning signs to look out for
10:25 - What darker skin populations need to know
13:25 - Sun protection myths and tips

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In this episode, Dr. Diane Reidy-Lagunes has a meaningful conversation with Dr. Alan Carver, an MSK neurologist specializing in end-of-life and palliative care, and Hadley Vlahos, a hospice nurse with over 1 million social followers and author of "The In-Between: Unforgettable Encounters During Life's Final Moments." Together, they offer advice for both patients and caregivers about transitioning to hospice care, managing fear, and finding peace in one's final days. Sharing their own experiences, families describe how “joy and grief can walk together.”

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In this episode, Dr. Diane Reidy-Lagunes talks with MSK's infectious disease specialist and deputy physician-in-chief Dr. Monika Shah about the special concerns patients with cancer have about their risk for COVID-19 and vaccine safety while they’re in active treatment.

Learn more about MSK's COVID-19 Vaccine Information for Patients.

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In this episode, Dr. Diane Reidy-Lagunes speaks with Dr. Allison Applebaum, founder of the Caregivers Clinic at MSK, about the need to support cancer caregivers. She shares her own experience with her father and offers practical advice on navigating the healthcare system. This episode includes tips for managing intense emotions like anger, grief and guilt felt by people caring for a loved one with a serious illness. The challenge can be difficult and heartbreaking, but Dr. Applebaum says it’s possible to find profound meaning in the experience of being a cancer caregiver.

For more caregiver tips and support, listen to Episode 13: "Cancer and Caregivers: Navigating Stress, Worry and Other Challenges."

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Did you know lung cancer is more deadly than breast, colon and prostate cancers combined? Yet it gets less than half the funding. Why is that? In this episode, Dr. Diane Reidy-Lagunes sits down with thoracic surgeon and attending physician at MSK, Dr. Bernard Park, and chair of the Lung Cancer Research Foundation, Reina Honts, to discuss why one of the most common cancers is also the most stigmatized.

MSK’s lung screening tool

Episode Chapters:
3:38 – Causes and effects of stigma
8:12 – Risk factors and screening guidelines
15:58 – Awareness and fundraising hurdles
18:51 – Hope and advice

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In this episode, Dr. Diane Reidy-Lagunes speaks with MSK’s chair of psychiatry, Dr. William Breitbart, about the unique mental toll that a worldwide pandemic has on cancer patients and caregivers alike. Dr. Breitbart shares strategies for coping and finding hope in the midst of uncertainty.

Learn more about MSK's Support Services.

Learn more about MSK's COVID-19 Vaccine Information for Patients.

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Taking on the role of caregiver can be one of the most important — and overwhelming — jobs you’ll ever have. In this episode, Dr. Diane Reidy-Lagunes chats with MSK social worker Jacob Maier about what you need to know and how to care for yourself while caregiving.

Learn more about MSK's Caregiver Support Services.

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Spanish episode #3   |   Episodio #3 en español

Un reciente ensayo clínico para el cáncer de recto dirigido por Memorial Sloan Kettering ha captado la atención de médicos oncólogos y científicos del cáncer alrededor del mundo. Como un milagro, en un subconjunto de pacientes con la composición genética adecuada, una infusión intravenosa de inmunoterapia provocó una remisión completa. Los médicos se sorprendieron. El cáncer desapareció en todos los pacientes inscritos en el ensayo clínico. Los resultados son tan impresionantes que se publicaron en The New England Journal of Medicine y se presentaron en la reunión de oncólogos clínicos más grande del país en junio de 2022.

En este episodio, la Dra. Diane Reidy-Lagunes habla con los diseñadores de este estudio, los Dres. Andrea Cercek y Luis Diaz, sobre lo que significa esta noticia innovadora para los pacientes con cáncer y la comunidad científica en el futuro.

Más información sobre el Centro para el cáncer colorrectal y gastrointestinal de aparición temprana de MSK.

Vea todos los episodios de Cancer Straight Talk en Español.

Breakthrough Rectal Cancer Drug Trial: What It Means For You

A recent clinical trial for rectal cancer headed up by Memorial Sloan Kettering has grabbed the attention of medical oncologists and cancer scientists around the world. Like a miracle, in a subset of patients with the right genetic makeup, an IV infusion of an immunotherapy caused a complete remission. The doctors were shocked. The cancer disappeared in every single patient enrolled on trial. The results are so impressive they were published in The New England Journal of Medicine and featured at the nation’s largest gathering of clinical oncologists in June 2022.

In this episode, Dr. Diane Reidy-Lagunes speaks with the designers of this study, Drs. Andrea Cercek and Luis Diaz, on what this groundbreaking news means for cancer patients and the scientific community moving forward.

Learn more about MSK’s Center for Young Onset Colorectal and Gastrointestinal Cancer

See all episodes of Cancer Straight Talk en Español.

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Spanish episode #1   |   Episodio #1 en español

En la víspera de Navidad de 2004, Belkis Chalas se enteró de que tenía cáncer del intestino delgado en etapa 4 y apenas meses de vida. Como madre de dos hijos, no pudo evitar preguntar: "¿Por qué yo?" Luego encontró Memorial Sloan Kettering. En este episodio, la Dra. Diane Reidy-Lagunes habla con Belkis, ahora una de sus pacientes más queridas. Conversaron sobre cómo manejó su devastador diagnóstico hace 18 años y pudo continuar construyendo una vida satisfactoria a pesar de las incógnitas diarias. La enfermera de Belkis, Elizabeth Cruz, también se une al programa para compartir ideas sobre cómo se propaga el cáncer, qué podemos hacer para prevenirlo y su filosofía de atención compasiva.

Vea todos los episodios de Cancer Straight Talk en Español.

“My Children Were My Motivation”: One Mother’s Fight to Stay Alive

On Christmas Eve 2004, Belkis Chalas learned she had stage 4 cancer of the small intestine and months to live. As a mother of two, she couldn’t help but ask, “Why me?” Then she found Memorial Sloan Kettering. In this episode, Dr. Diane Reidy-Lagunes talks to Belkis – now one of her dearest patients – about how she handled her devastating diagnosis 18 years ago and went on to build a fulfilling life despite the daily unknowns. Belkis’ nurse, Elizabeth Cruz, also joins the show to share insights into how cancer spreads, what we can do to prevent it, and her philosophy of compassionate care.

See all episodes of Cancer Straight Talk en Español.

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In this episode, Dr. Diane Reidy-Lagunes talks to medical oncologist Dr. Santosha Vardhana about sugar and cancer. What is our favorite food’s metabolic role in cancer and in treatment?

For more information or to ask a question, please visit MSKCC.org/podcast

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While the holidays are meant to be a season of celebration, reflection and spending time with family and friends, it can also be a time of anxiety, grief or loneliness for those living with the reality of cancer. How does one find peace and meaning in the swarm of emotions that cancer brings up? In this episode, Dr. Diane Reidy-Lagunes and MSK chaplain Brian Kelly share their thoughts on what makes life meaningful and how to find your light in the darkest of times.

Listen to last year’s conversation with MSK psychologist Dr. Wendy Lichtenthal on gratitude and grief at the holidays.

Read "Coping With Grief: 7 Things to Remember When Dealing with Loss"

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In this episode, Dr. Diane Reidy-Lagunes and Dr. Alex Drilon, Chief of MSK's Early Drug Development Service, answer the most common questions about participating in clinical trials. Through hearing the experience of patients, they discuss the practical aspects as well as the fears and misconceptions associated with clinical trials. They explain their rigorous development, different phases, and potential to save patients’ lives now and in the future.

MSK is proud to support the key initiatives of the National Cancer Plan by helping to develop effective treatments and end cancer as we know it. Click here to learn more about the National Cancer Plan.

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In this episode, Dr. Diane Reidy-Lagunes talks to pain management physician Dr. Neal Rakesh, and neurologist Dr. Anna DeForest, about the many options patients and doctors have to treat pain, including different therapies, safely managed painkillers, injections, and the possibility (and effectiveness) of psychedelics in the future.

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In this episode, Dr. Diane Reidy-Lagunes speaks with medical oncologist Dr. Matthew Matasar. They drill down to the cancer basics, explaining the staging system, the treatment options, and the role of clinical trials.

For more information or to ask a question, please visit MSKCC.org/podcast

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How does one find gratitude while living with cancer? Can gratitude and grief exist at the same time? What are some tools for managing the two? Join us as Dr. Diane Reidy-Lagunes and MSK clinical psychologist Dr. Wendy Lichtenthal hear from past guests of the podcast – patients, caregivers and clinicians – on how they're finding gratitude this holiday season. 

Read "Coping With Grief: 7 Things to Remember When Dealing with Loss"

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In this special episode, MSK patients, caregivers and clinicians share the miracles they’ve witnessed, even in the darkest of times. From life-saving medicine to gratitude for caregivers and a surprise romance, these stories remind us of the power of human connection.

Episode Chapters:
1:15 - A Marathon Bond
5:09 - 2000 Miles Apart, United by a Breakthrough
7:55 - Showing Up for the Little Things
9:42 - Love After Loss, With Help from Two Angels
13:10 - More Time, More Memories: Marley’s Gift
14:57 - A Village for Ryan: MSK’s Creative Care
19:39 - The Healing Touch: Cecilia’s Miracle
22:13 - Cancer Hits Home for Dr. Reidy
23:28 - The Gift of Meaning: Michael's "Revelation"

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In this episode, Dr. Diane Reidy-Lagunes speaks with Dr. John Mulhall, director of Male Sexual and Reproductive Medicine at MSK and editor-in-chief of The Journal of Sexual Medicine, to discuss the impacts of cancer and its treatment on men’s sexual health. Dr. Mulhall gives advice to help men regain their sexual function, both physically and emotionally, and provides insights on the latest therapies, products, and myths surrounding the subject. Some content may not be suitable for children.

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In this episode, Dr. Diane Reidy-Lagunes sits down with MSK oncodermatologist Dr. Mario Lacouture and clinical nurse Sheryl Scott to discuss the most effective ways of preventing or mitigating the side effects of chemotherapy and radiation. They provide tips for living with fatigue, keeping or regrowing hair, soothing skin rashes, protecting nails, reducing nausea and more.

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In this episode, Dr. Diane Reidy-Lagunes sits down with MSK’s Dr. Neil Iyengar, a nationally recognized expert on the relationship between obesity, metabolic health, and cancer. Together, they discuss the intriguing connection between a new class of weight loss drugs, called GLP-1 agonists, and cancer risk reduction. They explore how medications like Ozempic, Wegovy, Mounjaro and others, which were originally designed for diabetes, are not only effective for weight loss but may also lower the risk of developing obesity-related cancers. They explain how those drugs work within the body to deliver potential benefits, the limitations of current studies, and what weight loss drugs mean for both cancer prevention and treatment.

Episode Chapters:
1:35 - How do these drugs cause weight loss?
3:08 - What cancers could these drugs help prevent?
4:29 - How exactly do they prevent cancer?
6:10 - Should people with cancer take these drugs?
7:42 - What happens when you stop taking them?
10:56 - Potential side effects
12:25 - Limitations of recent study and breast cancer prevention
14:36 - 3 lifestyle tips to prevent and treat cancer

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Discover the revolutionary potential of CAR T-cell therapy as a possible cure for some types of cancer. In this episode, Dr. Diane Reidy-Lagunes speaks with the pioneer of CAR T-cell therapy, MSK immunologist Dr. Michel Sadelain, as well as cellular therapist Dr. Jae Park, about the intricate process of modifying a patient’s own immune cells to target and eliminate cancer cells. They discuss its origin, clinical success in treating blood cancers like lymphoma and leukemia, and potential side effects. Dr. Sadelain addresses cost concerns, proposing strategies to enhance accessibility, while both doctors express optimism for CAR T-cell therapy’s future in treating, and maybe curing, a wider range of cancers, including solid tumors.

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In this episode, Dr. Diane Reidy-Lagunes chats with Dr. Lee Jones, exercise scientist at MSK, and Charlie Sweeney, marathon runner and cancer survivor, about the recent findings on the benefits of exercise and its role in the prevention and treatment of cancer. 

For more information or to ask a question, please visit MSKCC.org/podcast

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In this episode, Dr. Diane Reidy-Lagunes speaks with 3 women breaking new ground in the field of cancer research: Dr. Karuna Ganesh studies metastasis and how cancer spreads, Dr. Chrysothemis Brown is unlocking secrets of our immune system to fight cancer, and Marie-Josée Kravis has donated generously to support women in cancer research. Together, they discuss their pioneering research, the importance of mentorship in science, and the critical role philanthropy plays in the biggest breakthroughs.

Learn more about the work of women at MSK.

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In this episode, Dr. Diane Reidy-Lagunes speaks with Dr. Neil Iyengar, a breast medical oncologist and MSK’s leading researcher on diet, metabolism, and cancer. Together, they debunk myths surrounding diet trends, exercise, and the relationship between fat tissue and cancer.

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What makes a good pain remedy – chemically, mentally, legally? Is it better as an edible, oil or vapor? And how does one even begin to figure out dosing? These are the questions Dr. Diane Reidy-Lagunes explores in this discussion with MSK’s Director of Pediatric Integrated Medicine, Dr. Nirupa Raghunathan, and cancer survivor and winner of TV’s “Survivor: Africa”, Ethan Zohn. In this episode, Dr. Raghunathan and Ethan break down the chemical components of one of nature’s best pain remedies and outline what we still don’t know about the little green herb that’s going from taboo to commonplace on prescriptions across America.

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The negative impact of medical expenses on patients is known as financial toxicity. It’s one of the most universal and devastating side effects among cancer patients and their families, and it’s growing. Is there any hope on the horizon? In this episode, Dr. Diane Reidy-Lagunes gets answers and advice from two champions of this issue: Dr. Fumiko Chino, radiation oncologist and inaugural winner of the ASCO Excellence in Equity Award; and Dr. Emeline Aviki, gynecologic surgeon and former head of the Affordability Working Group. Dr. Chino and Dr. Aviki share tips for choosing the right insurance plan, oral versus IV treatments, planning ahead with your loved ones and resources for aid. 

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In this episode, Dr. Diane Reidy-Lagunes speaks with her patient Christine about the difficult decision to end treatment.

Watch the video of their conversation here.

For more information or to ask a question, please visit MSKCC.org/podcast

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Learn what you need to know about early-stage prostate cancer, from risk factors to treatment options and how to tackle their side effects. In this episode, Dr. Diane Reidy-Lagunes is joined by medical oncologist Dr. Dana Rathkopf, radiation oncologist Dr. Sean McBride, and urologic surgeon Dr. Behfar Ehdaie. Together, they provide an overview of treatment options for people diagnosed with prostate cancer, including active surveillance, internal and external radiation, surgery and hormone therapy. They offer guidance on navigating these choices and mitigating their side effects with state-of-the-art technology and holistic support services. 

Episode Chapters:
1:24 – Risk factors and screening
4:12 – Active surveillance
6:12 – Radiation
11:31 – Surgery 
14:53 – Hormone therapy 
20:38 – New and upcoming treatments

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For nearly half of all breast cancer patients – those with low levels of the HER2 protein – targeted treatment options have always been limited. Palliative chemo has been the standard of care in stage 4 metastatic patients – until now. In this episode, Dr. Diane Reidy-Lagunes talks with Dr. Shanu Modi, the lead researcher of a groundbreaking MSK trial that proved a drug that combines an antibody with a chemotherapy – trastuzumab deruxtecan (T-DXd) – can control cancer cells and extend survival in stage 4 HER2-low breast cancer patients. With a fresh FDA approval, T-DXd is now being tested on other cancers and changing the way oncologists treat their patients.

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In this episode, Dr. Diane Reidy-Lagunes speaks with Elizabeth Cruz, a registered nurse at MSK, and Stacey Peltz, an eight-year cancer survivor and warrior. Together, they’ll run down what you need to know to prepare for treatment and how to live well on chemotherapy.

For more information or to ask a question, please visit MSKCC.org/podcast

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In this episode, Dr. Diane Reidy-Lagunes talks with former New York Mets president and MSK patient, Sandy Alderson, along with his dedicated team of doctors at Memorial Sloan Kettering. They discuss Sandy’s unique journey with appendix cancer and how experts from various disciplines came together to save his life, a testament to MSK’s multidisciplinary care model. Sandy also dives into the reasons he kept his diagnosis private for eight years, and highlights the power of mental distractions and trust in your medical team when living with cancer.

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In this episode, Dr. Diane Reidy-Lagunes welcomes MSK exercise scientist Dr. Lee Jones back to the show to discuss the most recent findings about the effects of exercise on cancer prevention, treatment and recovery. Dr. Jones provides advice for patients to stay physically fit and battle fatigue, as well as the most effective training regimen for anybody, with or without cancer. 

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In this episode, Dr. Diane Reidy-Lagunes speaks with two MSK clinical social workers, Hadley Maya and Natalie Santos, about how parents who've been diagnosed with cancer can talk to their children. They offer compassionate guidance on being honest with kids to prepare them for changes in family routines or treatment side effects, helping them feel more secure during a difficult time. With practical tips and real-life examples, this conversation offers advice for parents navigating one of the hardest discussions imaginable, while making sure their children feel supported and can continue being kids.

Learn more about MSK’s Talking with Children about Cancer program

Additional resources mentioned in this episode:
Red Door Community
CancerCare
Bright Spot Network

Episode Chapters:
1:14 - Should I tell my child I have cancer?
3:01 - Should it be one conversation or more?
4:16 - Advice from a mother with cancer
5:27 - Should I put on a brave face? What if I cry?
8:30 - How do I explain side effects like hair loss?
10:36 - Advice from a mother who lost her hair
11:43 - How do I tell my child I may die from cancer?
14:24 - Advice from a mother with months to live
16:02 - Age-appropriate guidelines for talking to kids
21:30 - Advice from a father on age-appropriate talks
22:39 - Advice from a daughter on having a sick mother
24:32 - What if my teenager doesn't respond well?
25:32 - Advice for the surviving parent
26:17 - Resources to help parents with cancer
28:09 - A note on trusting your child

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